CN1274306C - 包含加巴喷丁或其类似物和α-氨基酰胺的药物组合物及其止痛应用 - Google Patents

包含加巴喷丁或其类似物和α-氨基酰胺的药物组合物及其止痛应用 Download PDF

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Publication number
CN1274306C
CN1274306C CNB028185897A CN02818589A CN1274306C CN 1274306 C CN1274306 C CN 1274306C CN B028185897 A CNB028185897 A CN B028185897A CN 02818589 A CN02818589 A CN 02818589A CN 1274306 C CN1274306 C CN 1274306C
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CN
China
Prior art keywords
gbp
gabapentin
pharmaceutical composition
alpha
pain
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB028185897A
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English (en)
Chinese (zh)
Other versions
CN1556720A (zh
Inventor
P·萨尔瓦提
O·维恩罗尼
R·马吉
R·法里洛
L·贝纳蒂
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Newron Pharmaceuticals SpA
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Newron Pharmaceuticals SpA
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Publication date
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Publication of CN1556720A publication Critical patent/CN1556720A/zh
Application granted granted Critical
Publication of CN1274306C publication Critical patent/CN1274306C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB028185897A 2001-09-03 2002-08-09 包含加巴喷丁或其类似物和α-氨基酰胺的药物组合物及其止痛应用 Expired - Lifetime CN1274306C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01121069 2001-09-03
EP01121069.7 2001-09-03

Publications (2)

Publication Number Publication Date
CN1556720A CN1556720A (zh) 2004-12-22
CN1274306C true CN1274306C (zh) 2006-09-13

Family

ID=8178510

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028185897A Expired - Lifetime CN1274306C (zh) 2001-09-03 2002-08-09 包含加巴喷丁或其类似物和α-氨基酰胺的药物组合物及其止痛应用

Country Status (20)

Country Link
US (2) US8084447B2 (https=)
EP (1) EP1423168B1 (https=)
JP (1) JP4350508B2 (https=)
KR (1) KR100890875B1 (https=)
CN (1) CN1274306C (https=)
AT (1) ATE317280T1 (https=)
AU (1) AU2002333374B2 (https=)
BR (1) BRPI0212298B8 (https=)
CA (1) CA2459470C (https=)
DE (1) DE60209152T2 (https=)
DK (1) DK1423168T3 (https=)
ES (1) ES2253579T3 (https=)
IL (2) IL160523A0 (https=)
MX (1) MXPA04002009A (https=)
NO (1) NO331298B1 (https=)
NZ (1) NZ531586A (https=)
PT (1) PT1423168E (https=)
RU (1) RU2295337C2 (https=)
SI (1) SI1423168T1 (https=)
WO (1) WO2003020273A2 (https=)

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EP1963280B1 (en) 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
HUE030233T2 (en) 2006-06-19 2017-04-28 Newron Pharm Spa High purity 2- [4- (3- and 2-fluorobenzyloxy) benzylamino] propanamides for use as medicaments and pharmaceutical compositions containing them
PT2155663T (pt) 2007-06-15 2018-01-16 Newron Pharm Spa Derivados de 2-[2-(fenil)etilamino]alcanamida substituídos e sua utilização como moduladores dos canais de sódio e/ou de cálcio
CA2936209C (en) 2007-12-11 2020-02-11 Newron Pharmaceuticals S.P.A. Process for the production of 2-[4-(3- or 2-fluorobenzyloxy)benzylamino]propanamides with high purity degree
US9192681B2 (en) 2009-02-24 2015-11-24 Nektar Therapeutics Oligomer-amino acid conjugates
JP5808392B2 (ja) 2010-04-27 2015-11-10 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー ラルフィナミドメタンスルホネート塩またはそのr−エナンチオマーの製造方法
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IT201900006602A1 (it) * 2019-05-07 2020-11-07 Acraf Composizione farmaceutica per il trattamento del dolore neuropatico

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Also Published As

Publication number Publication date
US20040248978A1 (en) 2004-12-09
RU2295337C2 (ru) 2007-03-20
ES2253579T3 (es) 2006-06-01
CN1556720A (zh) 2004-12-22
US8710040B2 (en) 2014-04-29
AU2002333374A2 (en) 2003-03-18
WO2003020273A3 (en) 2003-09-04
IL160523A (en) 2009-02-11
CA2459470C (en) 2010-10-12
CA2459470A1 (en) 2003-03-13
NZ531586A (en) 2005-09-30
BRPI0212298B1 (pt) 2015-11-03
IL160523A0 (en) 2004-07-25
KR100890875B1 (ko) 2009-03-31
AU2002333374B2 (en) 2007-03-22
EP1423168B1 (en) 2006-02-08
DK1423168T3 (da) 2006-05-15
NO20040907L (no) 2004-05-14
RU2004110041A (ru) 2005-03-10
SI1423168T1 (sl) 2006-06-30
US20120142777A1 (en) 2012-06-07
NO331298B1 (no) 2011-11-21
ATE317280T1 (de) 2006-02-15
HK1070305A1 (en) 2005-06-17
PT1423168E (pt) 2006-05-31
JP4350508B2 (ja) 2009-10-21
JP2005504782A (ja) 2005-02-17
BRPI0212298B8 (pt) 2021-05-25
WO2003020273A2 (en) 2003-03-13
US8084447B2 (en) 2011-12-27
MXPA04002009A (es) 2004-07-08
KR20040034686A (ko) 2004-04-28
EP1423168A2 (en) 2004-06-02
BR0212298A (pt) 2004-09-14
DE60209152T2 (de) 2006-08-03
DE60209152D1 (de) 2006-04-20

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