ATE317280T1 - Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung - Google Patents

Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung

Info

Publication number
ATE317280T1
ATE317280T1 AT02797573T AT02797573T ATE317280T1 AT E317280 T1 ATE317280 T1 AT E317280T1 AT 02797573 T AT02797573 T AT 02797573T AT 02797573 T AT02797573 T AT 02797573T AT E317280 T1 ATE317280 T1 AT E317280T1
Authority
AT
Austria
Prior art keywords
aminoamide
analogue
alpha
pharmaceutical composition
analgesic use
Prior art date
Application number
AT02797573T
Other languages
German (de)
English (en)
Inventor
Patricia Salvati
Orietta Veneroni
Roberto Maj
Ruggero Fariello
Luca Benatti
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of ATE317280T1 publication Critical patent/ATE317280T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02797573T 2001-09-03 2002-08-09 Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung ATE317280T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01121069 2001-09-03

Publications (1)

Publication Number Publication Date
ATE317280T1 true ATE317280T1 (de) 2006-02-15

Family

ID=8178510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02797573T ATE317280T1 (de) 2001-09-03 2002-08-09 Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung

Country Status (20)

Country Link
US (2) US8084447B2 (https=)
EP (1) EP1423168B1 (https=)
JP (1) JP4350508B2 (https=)
KR (1) KR100890875B1 (https=)
CN (1) CN1274306C (https=)
AT (1) ATE317280T1 (https=)
AU (1) AU2002333374B2 (https=)
BR (1) BRPI0212298B8 (https=)
CA (1) CA2459470C (https=)
DE (1) DE60209152T2 (https=)
DK (1) DK1423168T3 (https=)
ES (1) ES2253579T3 (https=)
IL (2) IL160523A0 (https=)
MX (1) MXPA04002009A (https=)
NO (1) NO331298B1 (https=)
NZ (1) NZ531586A (https=)
PT (1) PT1423168E (https=)
RU (1) RU2295337C2 (https=)
SI (1) SI1423168T1 (https=)
WO (1) WO2003020273A2 (https=)

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US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
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EP1557166A1 (en) 2004-01-21 2005-07-27 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders
DK1809271T5 (da) * 2004-09-10 2010-12-06 Newron Pharm Spa Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer
US20070043241A1 (en) * 2005-05-10 2007-02-22 Lilach Hedvati Optical resolution of 3-carbamoylmethyl-5-methylhexanoic acid
CN100410242C (zh) * 2005-06-23 2008-08-13 江苏恩华药业股份有限公司 普瑞巴林中间体及其制备方法
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EP1798236A1 (en) * 2005-12-13 2007-06-20 EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. Process for the preparation of 3-pyridyl-1-hydroxyethylidene-1,1- biphosphonic acid and hydrated forms thereof
EP1963280B1 (en) 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
HUE030233T2 (en) * 2006-06-19 2017-04-28 Newron Pharm Spa High purity 2- [4- (3- and 2-fluorobenzyloxy) benzylamino] propanamides for use as medicaments and pharmaceutical compositions containing them
CA2689561C (en) 2007-06-15 2015-11-17 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
US8530701B2 (en) 2007-12-11 2013-09-10 Newron Pharmaceuticals, S.P.A. High purity 2-[4-(3- OR 2-fluorobenzyloxy)benzylamino]propanamides and methods of use thereof
US9192681B2 (en) 2009-02-24 2015-11-24 Nektar Therapeutics Oligomer-amino acid conjugates
SI2563355T1 (sl) 2010-04-27 2016-10-28 Newron Pharmaceuticals S.P.A. Postopek za izdelavo metansulfonatnih soli ralfinamida ali njihovih R-enantiomerov
CN112955145A (zh) * 2018-09-04 2021-06-11 密涅瓦神经科学有限公司 使用苯氧丙胺化合物治疗疼痛的方法
IT201900006602A1 (it) * 2019-05-07 2020-11-07 Acraf Composizione farmaceutica per il trattamento del dolore neuropatico
CN120025292B (zh) * 2025-01-06 2026-04-28 江苏海洋大学 一种具有协同镇痛作用的化合物及其药物组合物、制备方法和用途

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Also Published As

Publication number Publication date
WO2003020273A3 (en) 2003-09-04
RU2004110041A (ru) 2005-03-10
EP1423168A2 (en) 2004-06-02
BR0212298A (pt) 2004-09-14
KR20040034686A (ko) 2004-04-28
JP4350508B2 (ja) 2009-10-21
US20040248978A1 (en) 2004-12-09
DK1423168T3 (da) 2006-05-15
HK1070305A1 (en) 2005-06-17
WO2003020273A2 (en) 2003-03-13
DE60209152T2 (de) 2006-08-03
EP1423168B1 (en) 2006-02-08
US8710040B2 (en) 2014-04-29
JP2005504782A (ja) 2005-02-17
ES2253579T3 (es) 2006-06-01
CN1556720A (zh) 2004-12-22
RU2295337C2 (ru) 2007-03-20
PT1423168E (pt) 2006-05-31
DE60209152D1 (de) 2006-04-20
AU2002333374A2 (en) 2003-03-18
NO20040907L (no) 2004-05-14
BRPI0212298B1 (pt) 2015-11-03
KR100890875B1 (ko) 2009-03-31
CA2459470C (en) 2010-10-12
CA2459470A1 (en) 2003-03-13
NO331298B1 (no) 2011-11-21
IL160523A0 (en) 2004-07-25
US8084447B2 (en) 2011-12-27
IL160523A (en) 2009-02-11
MXPA04002009A (es) 2004-07-08
US20120142777A1 (en) 2012-06-07
BRPI0212298B8 (pt) 2021-05-25
AU2002333374B2 (en) 2007-03-22
CN1274306C (zh) 2006-09-13
NZ531586A (en) 2005-09-30
SI1423168T1 (sl) 2006-06-30

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