CN1059516A - 联苯甲腈的制备方法 - Google Patents

联苯甲腈的制备方法 Download PDF

Info

Publication number
CN1059516A
CN1059516A CN91105206A CN91105206A CN1059516A CN 1059516 A CN1059516 A CN 1059516A CN 91105206 A CN91105206 A CN 91105206A CN 91105206 A CN91105206 A CN 91105206A CN 1059516 A CN1059516 A CN 1059516A
Authority
CN
China
Prior art keywords
formula
compound
alkyl
group
palladium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN91105206A
Other languages
English (en)
Chinese (zh)
Inventor
D·A·罗伯特斯
S·T·拉塞尔
J·D·皮塔姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10680408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1059516(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of CN1059516A publication Critical patent/CN1059516A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Glass Compositions (AREA)
  • Turning (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Air Bags (AREA)
  • Electrotherapy Devices (AREA)
CN91105206A 1990-08-09 1991-07-29 联苯甲腈的制备方法 Pending CN1059516A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909017482A GB9017482D0 (en) 1990-08-09 1990-08-09 Manufacturing process
GB9017482.2 1990-08-09

Publications (1)

Publication Number Publication Date
CN1059516A true CN1059516A (zh) 1992-03-18

Family

ID=10680408

Family Applications (1)

Application Number Title Priority Date Filing Date
CN91105206A Pending CN1059516A (zh) 1990-08-09 1991-07-29 联苯甲腈的制备方法

Country Status (23)

Country Link
EP (1) EP0470795B2 (enExample)
JP (1) JP3001298B2 (enExample)
KR (1) KR920004337A (enExample)
CN (1) CN1059516A (enExample)
AT (1) ATE117672T1 (enExample)
AU (1) AU646473B2 (enExample)
CA (1) CA2047369A1 (enExample)
CS (1) CS241391A3 (enExample)
DE (1) DE69106977T3 (enExample)
ES (1) ES2067159T3 (enExample)
FI (1) FI913640A7 (enExample)
GB (2) GB9017482D0 (enExample)
HU (1) HU207841B (enExample)
IL (1) IL98862A0 (enExample)
NO (1) NO174502B (enExample)
NZ (1) NZ239026A (enExample)
PL (1) PL291370A1 (enExample)
PT (1) PT98608A (enExample)
RU (1) RU2026285C1 (enExample)
TW (1) TW198710B (enExample)
YU (1) YU137891A (enExample)
ZA (1) ZA915566B (enExample)
ZW (1) ZW9591A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117623932A (zh) * 2023-11-30 2024-03-01 江苏康恒化工有限公司 中间体2，2’-二硝基联苯的合成方法

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ATE117294T1 (de) * 1989-08-11 1995-02-15 Ici Plc Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
FR2688507B1 (fr) * 1992-03-16 1994-05-06 Synthelabo Derives de l'acide tetrazolylbenzeneboronique, leur preparation et leur utilisation comme intermediaires de synthese.
FR2689887B1 (fr) * 1992-04-13 1995-06-23 Sanofi Elf Procede de preparation d'un derive de biphenyle.
FR2696746B1 (fr) * 1992-10-12 1994-11-18 Synthelabo Dérivés de l'acide benzèneborinique, leur préparation et leur utilisation comme intermédiaires de synthèse.
DE4423061C1 (de) * 1994-07-01 1996-01-18 Hoechst Ag Verfahren zur Herstellung von Biphenylen mit Palladacyclen als Katalysatoren
DE4426671A1 (de) * 1994-07-28 1996-02-01 Hoechst Ag Verfahren zur Kreuzkupplung von aromatischen Borverbindungen mit aromatischen Halogenverbindungen oder Perfluoralkylsulfonaten
KR100354802B1 (ko) * 1994-10-20 2002-12-26 한국화학연구원 테트라졸유도체의제조방법
JP2928982B2 (ja) 1994-10-27 1999-08-03 住化ファインケム株式会社 ４’−ブロモメチル−２−シアノビフェニルの製造法
DE19620023C2 (de) * 1996-05-17 2001-03-08 Celanese Chem Europe Gmbh Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane
US5922898A (en) * 1997-04-08 1999-07-13 Catalytica Pharmaceuticals, Inc. Process for preparing biaryl compounds
US6194599B1 (en) 1997-04-08 2001-02-27 Catalytica, Inc. Process for preparing biaryl compounds
WO1999047474A1 (en) 1998-03-18 1999-09-23 Ciba Specialty Chemicals Holding Inc. Coupling reactions with palladium catalysts
US6962999B2 (en) 2001-07-25 2005-11-08 Pharmacore, Inc. Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles
DE10211597A1 (de) 2002-03-15 2003-10-02 Merck Patent Gmbh Verfahren zur Herstellung von Ringverbindungen
ES2259412T3 (es) 2002-04-29 2006-10-01 Teva Pharmaceutical Industries Ltd. Procedimientos para la preparacion de losartan y losartan potasico.
DK1535901T3 (da) 2002-06-12 2008-04-07 Sumitomo Chemical Co Fremgangsmåde til fremstilling af 4' -brommethyl-2-cyanobiphenyl
US7105467B2 (en) 2003-07-08 2006-09-12 Pharmacore, Inc. Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives
US7105707B2 (en) 2003-12-17 2006-09-12 Pharmacore, Inc. Process for preparing alkynyl-substituted aromatic and heterocyclic compounds
JP2006151946A (ja) * 2004-04-30 2006-06-15 Konishi Kagaku Ind Co Ltd ジアリール誘導体の製造方法
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
JP5546451B2 (ja) 2007-06-04 2014-07-09 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP3241839B1 (en) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
DK2473476T3 (en) * 2009-08-31 2015-04-20 Bayer Ip Gmbh Tetraarylborat method for producing substituted biphenyls
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
HK1220696A1 (zh) 2013-03-15 2017-05-12 Bausch Health Ireland Limited 鸟苷酸环化酶激动剂及其用途
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
EP4424697A3 (en) 2013-06-05 2024-12-25 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
JP5975081B2 (ja) * 2013-09-30 2016-08-23 ダイキン工業株式会社 含フッ素ビアリール化合物の製造方法
CA3237199A1 (en) 2021-11-02 2023-05-11 Flare Therapeutics Inc. Pparg inverse agonists and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
JP2633338B2 (ja) * 1987-10-19 1997-07-23 イギリス国 側方がシアノ―置換されているテルフェニル
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
ATE117294T1 (de) * 1989-08-11 1995-02-15 Ici Plc Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117623932A (zh) * 2023-11-30 2024-03-01 江苏康恒化工有限公司 中间体2，2’-二硝基联苯的合成方法

Also Published As

Publication number Publication date
ZW9591A1 (en) 1992-06-10
PL291370A1 (en) 1992-11-16
IL98862A0 (en) 1992-07-15
PT98608A (pt) 1992-06-30
HU912481D0 (en) 1991-12-30
ATE117672T1 (de) 1995-02-15
AU8043691A (en) 1992-02-13
FI913640A7 (fi) 1992-02-10
GB9115244D0 (en) 1991-08-28
EP0470795A1 (en) 1992-02-12
KR920004337A (ko) 1992-03-27
ES2067159T3 (es) 1995-03-16
AU646473B2 (en) 1994-02-24
HUT59662A (en) 1992-06-29
DE69106977T3 (de) 2001-07-19
DE69106977D1 (de) 1995-03-09
TW198710B (enExample) 1993-01-21
ZA915566B (en) 1992-04-29
NO174502C (enExample) 1994-05-18
YU137891A (sh) 1994-06-10
NO913086L (no) 1992-02-10
JP3001298B2 (ja) 2000-01-24
FI913640A0 (fi) 1991-07-30
GB9017482D0 (en) 1990-09-26
DE69106977T2 (de) 1995-05-24
HU207841B (en) 1993-06-28
NO913086D0 (no) 1991-08-08
EP0470795B1 (en) 1995-01-25
NO174502B (no) 1994-02-07
CS241391A3 (en) 1992-03-18
NZ239026A (en) 1993-12-23
RU2026285C1 (ru) 1995-01-09
JPH04253949A (ja) 1992-09-09
EP0470795B2 (en) 2001-02-21
CA2047369A1 (en) 1992-02-10

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication