DK1535901T3 - Fremgangsmåde til fremstilling af 4' -brommethyl-2-cyanobiphenyl - Google Patents
Fremgangsmåde til fremstilling af 4' -brommethyl-2-cyanobiphenylInfo
- Publication number
- DK1535901T3 DK1535901T3 DK02788757T DK02788757T DK1535901T3 DK 1535901 T3 DK1535901 T3 DK 1535901T3 DK 02788757 T DK02788757 T DK 02788757T DK 02788757 T DK02788757 T DK 02788757T DK 1535901 T3 DK1535901 T3 DK 1535901T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyanobiphenyl
- bromomethyl
- bromine
- oxidant
- hydrogen bromide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002172016 | 2002-06-12 | ||
| PCT/JP2002/012847 WO2003106406A1 (ja) | 2002-06-12 | 2002-12-09 | ４’−ブロモメチル−２−シアノビフェニルの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1535901T3 true DK1535901T3 (da) | 2008-04-07 |
Family
ID=29727838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02788757T DK1535901T3 (da) | 2002-06-12 | 2002-12-09 | Fremgangsmåde til fremstilling af 4' -brommethyl-2-cyanobiphenyl |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6861549B2 (da) |
| EP (1) | EP1535901B8 (da) |
| JP (1) | JPWO2003106406A1 (da) |
| KR (1) | KR100885148B1 (da) |
| CN (1) | CN1285570C (da) |
| AT (1) | ATE388136T1 (da) |
| AU (1) | AU2002354446A1 (da) |
| DE (1) | DE60225486T2 (da) |
| DK (1) | DK1535901T3 (da) |
| ES (1) | ES2299616T3 (da) |
| PT (1) | PT1535901E (da) |
| WO (1) | WO2003106406A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003234832A1 (en) * | 2003-05-20 | 2004-12-13 | Sumitomo Chemical Company, Limited | Process for producing bromomethyl-substituted aromatic carboxylic ester compound |
| KR20090102883A (ko) * | 2004-09-02 | 2009-09-30 | 테바 파마슈티컬 인더스트리즈 리미티드 | 올메살탄 메독소밀의 정제 |
| US20070054948A1 (en) * | 2004-09-02 | 2007-03-08 | Lilach Hedvati | Purification of olmesartan medoxomil |
| US7528258B2 (en) * | 2004-09-02 | 2009-05-05 | Teva Pharmaceutical Industries Ltd | Preparation of olmesartan medoxomil |
| US20060258727A1 (en) * | 2005-01-03 | 2006-11-16 | Lilach Hedvati | Olmesartan medoxomil with reduced levels of impurities |
| JP2006206446A (ja) * | 2005-01-25 | 2006-08-10 | Sumitomo Chemical Co Ltd | アラルキルハライド化合物の脱ハロゲン化方法及びこれを用いるアラルキル化合物の回収方法 |
| CN101597243B (zh) * | 2009-06-26 | 2012-11-21 | 凯莱英生命科学技术(天津)有限公司 | 一种2-氰基-4’-溴甲基联苯的合成方法 |
| HUP0900788A2 (en) * | 2009-12-16 | 2011-11-28 | Sanofi Aventis | Process for producing 4-bromomethyl-biphenyl derivatives |
| CN108947870B (zh) * | 2018-07-23 | 2021-03-19 | 湖北宇阳药业有限公司 | 一种溴代沙坦联苯的制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334092C (en) | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| GB8806584D0 (en) * | 1988-03-19 | 1988-04-20 | Interox Chemicals Ltd | Bromination |
| GB9017480D0 (en) | 1990-08-09 | 1990-09-26 | Ici Plc | Chemical process |
| GB9017482D0 (en) | 1990-08-09 | 1990-09-26 | Ici Plc | Manufacturing process |
| JP2859791B2 (ja) | 1992-01-31 | 1999-02-24 | 吉富製薬株式会社 | ４−ブロモメチルビフェニル化合物の製造法 |
| FR2689887B1 (fr) * | 1992-04-13 | 1995-06-23 | Sanofi Elf | Procede de preparation d'un derive de biphenyle. |
| JPH06298684A (ja) | 1993-04-15 | 1994-10-25 | Sankyo Co Ltd | 新規な４−（２−置換）フェニルベンジルブロミド類の製造法 |
| JP2928982B2 (ja) * | 1994-10-27 | 1999-08-03 | 住化ファインケム株式会社 | ４’−ブロモメチル−２−シアノビフェニルの製造法 |
| US5892094A (en) * | 1997-01-08 | 1999-04-06 | Sumika Fine Chemicals Co., Ltd. | Process for preparing 4'-methyl-2-cyanobiphenyl |
| DE19712339C1 (de) * | 1997-03-25 | 1998-04-09 | Clariant Gmbh | Verfahren zur Herstellung von in 2'-Stellung substituierten 4-Brommethyl-biphenyl-Verbindungen |
| IT1291551B1 (it) * | 1997-04-11 | 1999-01-11 | Luso Farmaco Inst | Processo per la preparazione di composti 4-bromometil bifenilici |
| FR2771090B1 (fr) | 1997-11-17 | 2000-02-04 | Sanofi Sa | Procede de preparation de derives de bromomethyl-biphenyle |
| DE19757995A1 (de) | 1997-12-29 | 1999-07-08 | Great Lakes Chem Konstanz Gmbh | Verfahren zur Herstellung von aromatischen Brommethyl-Verbindungen |
| JP2000256298A (ja) * | 1999-03-05 | 2000-09-19 | Sumika Fine Chemicals Co Ltd | 芳香族α−ブロモアルキル化合物の製造方法 |
| JP2002088044A (ja) * | 2000-09-14 | 2002-03-27 | Sumitomo Seika Chem Co Ltd | ４’−ブロモメチル−２−シアノビフェニルの製造方法 |
-
2002
- 2002-12-09 AT AT02788757T patent/ATE388136T1/de active
- 2002-12-09 AU AU2002354446A patent/AU2002354446A1/en not_active Abandoned
- 2002-12-09 WO PCT/JP2002/012847 patent/WO2003106406A1/ja active IP Right Grant
- 2002-12-09 EP EP02788757A patent/EP1535901B8/en not_active Expired - Lifetime
- 2002-12-09 KR KR1020047020182A patent/KR100885148B1/ko not_active IP Right Cessation
- 2002-12-09 PT PT02788757T patent/PT1535901E/pt unknown
- 2002-12-09 ES ES02788757T patent/ES2299616T3/es not_active Expired - Lifetime
- 2002-12-09 DK DK02788757T patent/DK1535901T3/da active
- 2002-12-09 DE DE60225486T patent/DE60225486T2/de not_active Expired - Lifetime
- 2002-12-09 CN CNB028291190A patent/CN1285570C/zh not_active Expired - Fee Related
- 2002-12-09 JP JP2004513240A patent/JPWO2003106406A1/ja active Pending
- 2002-12-17 US US10/322,017 patent/US6861549B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6861549B2 (en) | 2005-03-01 |
| US20030233009A1 (en) | 2003-12-18 |
| EP1535901A1 (en) | 2005-06-01 |
| CN1628094A (zh) | 2005-06-15 |
| DE60225486T2 (de) | 2009-04-02 |
| DE60225486D1 (de) | 2008-04-17 |
| JPWO2003106406A1 (ja) | 2005-10-13 |
| EP1535901A4 (en) | 2006-04-12 |
| AU2002354446A1 (en) | 2003-12-31 |
| ATE388136T1 (de) | 2008-03-15 |
| ES2299616T3 (es) | 2008-06-01 |
| PT1535901E (pt) | 2008-04-10 |
| CN1285570C (zh) | 2006-11-22 |
| EP1535901B1 (en) | 2008-03-05 |
| KR20050010046A (ko) | 2005-01-26 |
| WO2003106406A1 (ja) | 2003-12-24 |
| EP1535901B8 (en) | 2008-09-24 |
| KR100885148B1 (ko) | 2009-02-23 |
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