CN102118968A - 新的三环化合物 - Google Patents

新的三环化合物 Download PDF

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Publication number
CN102118968A
CN102118968A CN2009801311819A CN200980131181A CN102118968A CN 102118968 A CN102118968 A CN 102118968A CN 2009801311819 A CN2009801311819 A CN 2009801311819A CN 200980131181 A CN200980131181 A CN 200980131181A CN 102118968 A CN102118968 A CN 102118968A
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CN2009801311819A
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Chinese (zh)
Inventor
N·维沙特
M·A·阿吉里亚迪
D·J·考德伍德
A·M·埃里克森
B·A·费亚门戈
K·E·弗兰克
M·弗里德曼
D·M·乔治
E·R·格德肯
N·S·约瑟夫索恩
B·C·李
M·J·莫里特科
K·D·斯图尔特
J·W·沃斯
G·A·怀莱士
L·王
K·R·沃勒
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AbbVie Inc
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Abbott Laboratories
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41415363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN102118968(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CN102118968A publication Critical patent/CN102118968A/zh
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
CN2009801311819A 2008-06-10 2009-06-09 新的三环化合物 Pending CN102118968A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US13159908P 2008-06-10 2008-06-10
US13160208P 2008-06-10 2008-06-10
US61/131602 2008-06-10
US61/131599 2008-06-10
US19015908P 2008-08-26 2008-08-26
US61/190159 2008-08-26
US20106408P 2008-12-05 2008-12-05
US61/201064 2008-12-05
PCT/US2009/046714 WO2009152133A1 (en) 2008-06-10 2009-06-09 Novel tricyclic compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201410747767.0A Division CN104592231A (zh) 2008-06-10 2009-06-09 新的三环化合物

Publications (1)

Publication Number Publication Date
CN102118968A true CN102118968A (zh) 2011-07-06

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CN201410747767.0A Pending CN104592231A (zh) 2008-06-10 2009-06-09 新的三环化合物
CN2009801311819A Pending CN102118968A (zh) 2008-06-10 2009-06-09 新的三环化合物

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US (5) US8962629B2 (enExample)
EP (2) EP3031324A3 (enExample)
JP (2) JP5748659B2 (enExample)
KR (2) KR101718384B1 (enExample)
CN (2) CN104592231A (enExample)
AR (1) AR072086A1 (enExample)
AU (1) AU2009257602B2 (enExample)
BR (1) BRPI0915374B1 (enExample)
CA (2) CA3000973A1 (enExample)
CL (1) CL2010001426A1 (enExample)
CO (1) CO6382083A2 (enExample)
CR (1) CR20160007A (enExample)
CY (1) CY1117165T1 (enExample)
DK (1) DK2299821T3 (enExample)
DO (2) DOP2010000382A (enExample)
EC (1) ECSP10010657A (enExample)
ES (1) ES2559403T3 (enExample)
HR (1) HRP20160098T1 (enExample)
HU (1) HUE028347T2 (enExample)
IL (1) IL209434A0 (enExample)
ME (1) ME02340B (enExample)
MX (1) MX2010013557A (enExample)
MY (1) MY161369A (enExample)
NO (1) NO20101688A1 (enExample)
NZ (1) NZ623922A (enExample)
PE (2) PE20140407A1 (enExample)
PL (1) PL2299821T3 (enExample)
PT (1) PT2299821E (enExample)
RS (1) RS54560B1 (enExample)
RU (2) RU2545023C9 (enExample)
SI (1) SI2299821T1 (enExample)
TW (3) TWI527819B (enExample)
UA (1) UA106045C2 (enExample)
UY (1) UY31881A (enExample)
WO (1) WO2009152133A1 (enExample)
ZA (1) ZA201008562B (enExample)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102711470A (zh) * 2009-12-01 2012-10-03 雅培制药有限公司 新的三环化合物
CN102711476A (zh) * 2009-12-01 2012-10-03 雅培制药有限公司 新的三环化合物
CN102961382A (zh) * 2012-11-28 2013-03-13 玉林师范学院 一种骨肉瘤细胞抑制剂及制备方法
CN103694168A (zh) * 2013-12-05 2014-04-02 贵州威顿晶磷电子材料有限公司 一种6-氯-4-三氟甲基-3-氰基吡啶的制备方法
CN103732597A (zh) * 2011-08-12 2014-04-16 日产化学工业株式会社 三环杂环化合物和jak抑制剂
WO2020088659A1 (en) * 2018-11-01 2020-05-07 Lynk Pharmaceuticals Co. Ltd. Tricyclic janus kinase 1 inhibitors, and compositions and methods thereof
CN112300180A (zh) * 2019-07-26 2021-02-02 珠海宇繁生物科技有限责任公司 一种irak4激酶抑制剂及其制备方法
WO2021051899A1 (zh) * 2019-09-16 2021-03-25 维眸生物科技（上海）有限公司 一种氰基取代的环肼衍生物及其应用
CN113332298A (zh) * 2021-05-27 2021-09-03 成都医学院 米诺环素作为酪氨酸激酶抑制剂的新用途

Families Citing this family (66)

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Publication number Priority date Publication date Assignee Title
SI2299821T1 (sl) 2008-06-10 2016-03-31 Abbvie Inc. Triciklične spojine
AU2010237859A1 (en) 2009-04-14 2011-11-03 Astellas Pharma Inc. Fused pyrrolopyridine derivative
ES2552805T3 (es) 2009-04-20 2015-12-02 Auspex Pharmaceuticals, Llc Inhibidores piperidínicos de la cinasa Janus 3
WO2011011594A2 (en) * 2009-07-23 2011-01-27 Shriners Hospitals For Children Intracellular toll-like receptors pathways and axonal degeneration
US8361962B2 (en) * 2009-07-27 2013-01-29 Roche Palo Alto Llc Tricyclic inhibitors of JAK
BR112012005382A2 (pt) 2009-09-10 2016-03-29 Hoffmann La Roche inibidores de jak
BR112012006176A2 (pt) 2009-09-21 2015-09-08 Hoffmann La Roche inibidores macrocíclicos de jak
ES2759949T3 (es) 2009-10-29 2020-05-12 Bristol Myers Squibb Co Compuestos heterocíclicos tricíclicos
WO2011082267A2 (en) 2009-12-30 2011-07-07 Arqule, Inc. Substituted triazolo-pyrazine compounds
CN102712640A (zh) * 2010-01-12 2012-10-03 弗·哈夫曼-拉罗切有限公司 三环杂环化合物、其组合物和应用方法
US8637529B2 (en) 2010-06-11 2014-01-28 AbbYie Inc. Pyrazolo[3,4-d]pyrimidine compounds
DE102011106849A1 (de) 2010-12-15 2012-06-21 Merck Patent Gmbh Verfahren zur Synthese N-N verknüpfter und um die N-N Bindung rotationsgehinderter bis-N-heterocyclische Carbene und deren Einsatz als Liganden für Metallkomplexe
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