CN101001945B - 一次性生物反应器系统及方法 - Google Patents
一次性生物反应器系统及方法 Download PDFInfo
- Publication number
- CN101001945B CN101001945B CN2005800265340A CN200580026534A CN101001945B CN 101001945 B CN101001945 B CN 101001945B CN 2005800265340 A CN2005800265340 A CN 2005800265340A CN 200580026534 A CN200580026534 A CN 200580026534A CN 101001945 B CN101001945 B CN 101001945B
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- China
- Prior art keywords
- impeller
- container
- reactor
- bio
- flexible plastic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/14—Bags
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/513—Flexible receptacles, e.g. bags supported by rigid containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
- B01F35/531—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom
- B01F35/5312—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom with vertical baffles mounted on the walls
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57714304P | 2004-06-04 | 2004-06-04 | |
US60/577,143 | 2004-06-04 | ||
US66925205P | 2005-04-07 | 2005-04-07 | |
US60/669,252 | 2005-04-07 | ||
PCT/US2005/020083 WO2005118771A2 (fr) | 2004-06-04 | 2005-06-06 | Systemes de bioreacteurs jetables et procedes associes |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201110402080.XA Division CN102492607B (zh) | 2004-06-04 | 2005-06-06 | 一次性生物反应器系统及方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101001945A CN101001945A (zh) | 2007-07-18 |
CN101001945B true CN101001945B (zh) | 2012-02-08 |
Family
ID=35197799
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800265340A Active CN101001945B (zh) | 2004-06-04 | 2005-06-06 | 一次性生物反应器系统及方法 |
CN201110402080.XA Active CN102492607B (zh) | 2004-06-04 | 2005-06-06 | 一次性生物反应器系统及方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201110402080.XA Active CN102492607B (zh) | 2004-06-04 | 2005-06-06 | 一次性生物反应器系统及方法 |
Country Status (15)
Country | Link |
---|---|
US (1) | US7629167B2 (fr) |
EP (1) | EP1773976B2 (fr) |
JP (1) | JP4680990B2 (fr) |
KR (1) | KR101021203B1 (fr) |
CN (2) | CN101001945B (fr) |
AU (1) | AU2005250500B2 (fr) |
BR (1) | BRPI0510648B1 (fr) |
CA (1) | CA2569405C (fr) |
CR (1) | CR8769A (fr) |
DK (1) | DK1773976T4 (fr) |
ES (1) | ES2612212T5 (fr) |
HK (1) | HK1112479A1 (fr) |
MX (1) | MXPA06014099A (fr) |
NO (1) | NO20070069L (fr) |
WO (1) | WO2005118771A2 (fr) |
Families Citing this family (234)
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- 2005-06-06 ES ES05763165T patent/ES2612212T5/es active Active
- 2005-06-06 CA CA2569405A patent/CA2569405C/fr active Active
- 2005-06-06 US US11/147,124 patent/US7629167B2/en active Active
- 2005-06-06 CN CN2005800265340A patent/CN101001945B/zh active Active
- 2005-06-06 CN CN201110402080.XA patent/CN102492607B/zh active Active
- 2005-06-06 EP EP05763165.7A patent/EP1773976B2/fr active Active
- 2005-06-06 MX MXPA06014099A patent/MXPA06014099A/es active IP Right Grant
- 2005-06-06 KR KR1020077000150A patent/KR101021203B1/ko active IP Right Grant
- 2005-06-06 AU AU2005250500A patent/AU2005250500B2/en active Active
- 2005-06-06 JP JP2007515688A patent/JP4680990B2/ja active Active
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Also Published As
Publication number | Publication date |
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ES2612212T3 (es) | 2017-05-12 |
MXPA06014099A (es) | 2007-05-09 |
JP4680990B2 (ja) | 2011-05-11 |
EP1773976A2 (fr) | 2007-04-18 |
US20050272146A1 (en) | 2005-12-08 |
EP1773976B2 (fr) | 2020-01-01 |
CA2569405A1 (fr) | 2005-12-15 |
NO20070069L (no) | 2007-03-05 |
AU2005250500B2 (en) | 2011-06-23 |
CN101001945A (zh) | 2007-07-18 |
CN102492607B (zh) | 2014-12-10 |
AU2005250500A1 (en) | 2005-12-15 |
BRPI0510648A (pt) | 2007-11-20 |
US7629167B2 (en) | 2009-12-08 |
EP1773976B1 (fr) | 2016-12-07 |
DK1773976T3 (en) | 2017-01-30 |
CA2569405C (fr) | 2011-05-03 |
ES2612212T5 (es) | 2020-06-25 |
CN102492607A (zh) | 2012-06-13 |
CR8769A (es) | 2007-08-28 |
WO2005118771A2 (fr) | 2005-12-15 |
BRPI0510648B1 (pt) | 2016-04-26 |
KR20070053200A (ko) | 2007-05-23 |
KR101021203B1 (ko) | 2011-03-11 |
HK1112479A1 (en) | 2008-09-05 |
JP2008501347A (ja) | 2008-01-24 |
WO2005118771A3 (fr) | 2006-02-02 |
DK1773976T4 (da) | 2020-02-10 |
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