CL2021000353A1 - Anticuerpo o fragmento de anticuerpo del mismo que comprende una región de unión que se une a un supresor del dominio vista, composición que lo comprende, su uso para tratar o prevenir el cáncer, ácido nucleico aislado, vector de expresión, célula hospedadora, método para producir dicho anticuerpo o fragmento del mismo, y artículo de fabricación (divisional de solicitud n° 01646-2016) - Google Patents

Anticuerpo o fragmento de anticuerpo del mismo que comprende una región de unión que se une a un supresor del dominio vista, composición que lo comprende, su uso para tratar o prevenir el cáncer, ácido nucleico aislado, vector de expresión, célula hospedadora, método para producir dicho anticuerpo o fragmento del mismo, y artículo de fabricación (divisional de solicitud n° 01646-2016)

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Publication number
CL2021000353A1
CL2021000353A1 CL2021000353A CL2021000353A CL2021000353A1 CL 2021000353 A1 CL2021000353 A1 CL 2021000353A1 CL 2021000353 A CL2021000353 A CL 2021000353A CL 2021000353 A CL2021000353 A CL 2021000353A CL 2021000353 A1 CL2021000353 A1 CL 2021000353A1
Authority
CL
Chile
Prior art keywords
antibody
fragment
suppressor
binds
treat
Prior art date
Application number
CL2021000353A
Other languages
English (en)
Inventor
Linda Snyder
Gordon Powers
Original Assignee
Janssen Pharmaceutica Nv
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52444326&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2021000353(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CL2021000353A1 publication Critical patent/CL2021000353A1/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/3023—Lung
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
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    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Abstract

La presente invención se refiere a nuevos anticuerpos y fragmentos que se unen al dominio V de la Ig supresora de la activación de linfocitos T (VISTA), métodos para su preparación y el uso de los mismos en el tratamiento del cáncer, incluyendo leucemias, linfomas, tumores sólidos y melanomas.
CL2021000353A 2013-12-24 2021-02-10 Anticuerpo o fragmento de anticuerpo del mismo que comprende una región de unión que se une a un supresor del dominio vista, composición que lo comprende, su uso para tratar o prevenir el cáncer, ácido nucleico aislado, vector de expresión, célula hospedadora, método para producir dicho anticuerpo o fragmento del mismo, y artículo de fabricación (divisional de solicitud n° 01646-2016) CL2021000353A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361920695P 2013-12-24 2013-12-24
US201462085086P 2014-11-26 2014-11-26

Publications (1)

Publication Number Publication Date
CL2021000353A1 true CL2021000353A1 (es) 2021-08-27

Family

ID=52444326

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2016001646A CL2016001646A1 (es) 2013-12-24 2016-06-24 Anticuerpos y fragmentos anti-vista
CL2019002428A CL2019002428A1 (es) 2013-12-24 2019-08-23 Anticuerpos y fragmentos anti-vista. (divisional solicitud 201601646).
CL2021000353A CL2021000353A1 (es) 2013-12-24 2021-02-10 Anticuerpo o fragmento de anticuerpo del mismo que comprende una región de unión que se une a un supresor del dominio vista, composición que lo comprende, su uso para tratar o prevenir el cáncer, ácido nucleico aislado, vector de expresión, célula hospedadora, método para producir dicho anticuerpo o fragmento del mismo, y artículo de fabricación (divisional de solicitud n° 01646-2016)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CL2016001646A CL2016001646A1 (es) 2013-12-24 2016-06-24 Anticuerpos y fragmentos anti-vista
CL2019002428A CL2019002428A1 (es) 2013-12-24 2019-08-23 Anticuerpos y fragmentos anti-vista. (divisional solicitud 201601646).

Country Status (32)

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US (3) US10273301B2 (es)
EP (3) EP3712174B1 (es)
JP (4) JP6590810B2 (es)
KR (2) KR102534681B1 (es)
CN (2) CN106661107B (es)
AU (4) AU2014372309C1 (es)
BR (1) BR112016014966B1 (es)
CA (2) CA3190821A1 (es)
CL (3) CL2016001646A1 (es)
DK (2) DK3087098T3 (es)
DO (1) DOP2016000153A (es)
EA (1) EA201691323A1 (es)
EC (1) ECSP16062894A (es)
ES (1) ES2920677T3 (es)
HR (1) HRP20220748T1 (es)
IL (3) IL290972B2 (es)
LT (1) LT3712174T (es)
MX (2) MX369173B (es)
MY (1) MY182431A (es)
NI (1) NI201600090A (es)
NZ (1) NZ721866A (es)
PE (1) PE20170254A1 (es)
PH (1) PH12016501244A1 (es)
PL (1) PL3712174T3 (es)
PT (1) PT3712174T (es)
RS (1) RS63295B1 (es)
SA (1) SA516371402B1 (es)
SG (4) SG10201805933TA (es)
SI (1) SI3712174T1 (es)
UA (1) UA125490C2 (es)
UY (1) UY35961A (es)
WO (1) WO2015097536A2 (es)

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* Cited by examiner, † Cited by third party
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MX342017B (es) 2010-03-26 2016-09-09 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
JP6368308B2 (ja) 2012-09-07 2018-08-01 トラスティーズ・オブ・ダートマス・カレッジ 癌の診断および治療のためのｖｉｓｔａ調節剤
SG10201805933TA (en) 2013-12-24 2018-08-30 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
US11123426B2 (en) 2014-06-11 2021-09-21 The Trustees Of Dartmouth College Use of vista agonists and antagonists to suppress or enhance humoral immunity
WO2016090347A1 (en) 2014-12-05 2016-06-09 Immunext, Inc. Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
MX2017014188A (es) 2015-05-07 2018-04-10 Agenus Inc Anticuerpos anti-ox40 y metodos para su uso.
BR112017027870A2 (pt) 2015-06-24 2018-08-28 Janssen Pharmaceutica Nv anticorpos e fragmentos anti-vista
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