CL2015002640A1 - Agentes inductores de la apoptosis para tratar el cáncer y enfermedades inmunes y autoinmunes - Google Patents
Agentes inductores de la apoptosis para tratar el cáncer y enfermedades inmunes y autoinmunesInfo
- Publication number
- CL2015002640A1 CL2015002640A1 CL2015002640A CL2015002640A CL2015002640A1 CL 2015002640 A1 CL2015002640 A1 CL 2015002640A1 CL 2015002640 A CL2015002640 A CL 2015002640A CL 2015002640 A CL2015002640 A CL 2015002640A CL 2015002640 A1 CL2015002640 A1 CL 2015002640A1
- Authority
- CL
- Chile
- Prior art keywords
- autoimmune
- treat cancer
- immune diseases
- inducing agents
- apoptosis inducing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781070P | 2013-03-14 | 2013-03-14 | |
| US14/176,506 US20140275082A1 (en) | 2013-03-14 | 2014-02-10 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2015002640A1 true CL2015002640A1 (es) | 2016-03-18 |
Family
ID=51529947
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2015002640A CL2015002640A1 (es) | 2013-03-14 | 2015-09-11 | Agentes inductores de la apoptosis para tratar el cáncer y enfermedades inmunes y autoinmunes |
| CL2018000353A CL2018000353A1 (es) | 2013-03-14 | 2018-02-07 | Agentes inductores de la apoptosis para tratar el cáncer y enfermedades inmunes y autoinmunes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2018000353A CL2018000353A1 (es) | 2013-03-14 | 2018-02-07 | Agentes inductores de la apoptosis para tratar el cáncer y enfermedades inmunes y autoinmunes |
Country Status (35)
| Country | Link |
|---|---|
| US (6) | US20140275082A1 (OSRAM) |
| EP (2) | EP2970257B1 (OSRAM) |
| JP (4) | JP6449222B2 (OSRAM) |
| KR (2) | KR20210021613A (OSRAM) |
| CN (2) | CN107987075B (OSRAM) |
| AR (2) | AR095263A1 (OSRAM) |
| AU (2) | AU2014242104B2 (OSRAM) |
| BR (1) | BR112015021115B1 (OSRAM) |
| CA (2) | CA2899041A1 (OSRAM) |
| CL (2) | CL2015002640A1 (OSRAM) |
| CR (1) | CR20150510A (OSRAM) |
| CY (1) | CY1120862T1 (OSRAM) |
| DK (1) | DK2970257T3 (OSRAM) |
| DO (1) | DOP2018000026A (OSRAM) |
| ES (1) | ES2689679T3 (OSRAM) |
| GT (1) | GT201500248A (OSRAM) |
| HR (1) | HRP20181403T8 (OSRAM) |
| HU (1) | HUE038983T2 (OSRAM) |
| IL (3) | IL240010B (OSRAM) |
| LT (1) | LT2970257T (OSRAM) |
| MX (2) | MX384490B (OSRAM) |
| MY (1) | MY178821A (OSRAM) |
| NZ (1) | NZ631701A (OSRAM) |
| PE (2) | PE20151555A1 (OSRAM) |
| PL (1) | PL2970257T4 (OSRAM) |
| PT (1) | PT2970257T (OSRAM) |
| RS (1) | RS57750B1 (OSRAM) |
| RU (2) | RU2018127315A (OSRAM) |
| SG (2) | SG11201507363UA (OSRAM) |
| SI (1) | SI2970257T1 (OSRAM) |
| TW (2) | TWI675835B (OSRAM) |
| UA (1) | UA120035C2 (OSRAM) |
| UY (1) | UY35406A (OSRAM) |
| WO (1) | WO2014158528A1 (OSRAM) |
| ZA (1) | ZA201505203B (OSRAM) |
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| KR20140119023A (ko) | 2011-12-13 | 2014-10-08 | 버크 인스티튜트 포 리서치 온 에이징 | 의료 요법을 개선하는 방법 |
| US20150064137A1 (en) | 2012-04-17 | 2015-03-05 | Kythera Biopharmaceuticals, Inc. | Use of engineered viruses to specifically kill senescent cells |
| US9901081B2 (en) | 2012-08-23 | 2018-02-27 | Buck Institute For Research On Aging | Transgenic mouse for determining the role of senescent cells in cancer |
| US9901080B2 (en) | 2012-08-23 | 2018-02-27 | Buck Institute For Research On Aging | Transgenic mouse having a transgene that converts a prodrug into a cytotoxic compound in senescent cells |
| US20140275082A1 (en) * | 2013-03-14 | 2014-09-18 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
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| CA2939121C (en) | 2014-01-28 | 2020-11-24 | Mayo Foundation For Medical Education And Research | Effective treatment of osteoarthritis, pulmonary disease, ophthalmic disease, and atherosclerosis by removing senescent cells at the site of the disease |
| US10328058B2 (en) | 2014-01-28 | 2019-06-25 | Mayo Foundation For Medical Education And Research | Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques |
| US20170216286A1 (en) | 2014-01-28 | 2017-08-03 | Mayo Foundation For Medical Education And Research | Killing senescent cells and treating senescence-associated conditions using a src inhibitor and a flavonoid |
| US20190269675A1 (en) | 2014-01-28 | 2019-09-05 | Buck Institute for Research and Aging | Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agents |
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| SG11201804259UA (en) | 2015-12-04 | 2018-06-28 | Novartis Ag | Antibody cytokine engrafted compositions and methods of use for immunoregulation |
| TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
| BR112018067550A2 (pt) * | 2016-02-27 | 2019-10-01 | Hpvvax, Llc. | métodos para tratar um paciente que tem câncer de pele, tumor benigno ou canceroso ou uma lesão associada a papilomavírus humano (hpv), e composição farmacêutica |
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