MX360541B - Agentes que inducen apoptosis para el tratamiento de cáncer y enfermedades inmunitarias y autoinmunitarias. - Google Patents
Agentes que inducen apoptosis para el tratamiento de cáncer y enfermedades inmunitarias y autoinmunitarias.Info
- Publication number
- MX360541B MX360541B MX2015011641A MX2015011641A MX360541B MX 360541 B MX360541 B MX 360541B MX 2015011641 A MX2015011641 A MX 2015011641A MX 2015011641 A MX2015011641 A MX 2015011641A MX 360541 B MX360541 B MX 360541B
- Authority
- MX
- Mexico
- Prior art keywords
- apoptosis
- immune
- cancer
- treatment
- autoimmune diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Abstract
Se describen en la presente compuestos que inhiben la actividad de proteínas Bcl-2 anti-apoptóticas, composiciones que contienen los compuestos y métodos para tratar enfermedades usando los compuestos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361781070P | 2013-03-14 | 2013-03-14 | |
US14/176,506 US20140275082A1 (en) | 2013-03-14 | 2014-02-10 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
PCT/US2014/017751 WO2014158528A1 (en) | 2013-03-14 | 2014-02-21 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015011641A MX2015011641A (es) | 2015-12-16 |
MX360541B true MX360541B (es) | 2018-10-19 |
Family
ID=51529947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015011641A MX360541B (es) | 2013-03-14 | 2014-02-21 | Agentes que inducen apoptosis para el tratamiento de cáncer y enfermedades inmunitarias y autoinmunitarias. |
Country Status (36)
Country | Link |
---|---|
US (6) | US20140275082A1 (es) |
EP (2) | EP2970257B1 (es) |
JP (4) | JP6449222B2 (es) |
KR (2) | KR102260645B1 (es) |
CN (2) | CN107987075B (es) |
AR (2) | AR095263A1 (es) |
AU (2) | AU2014242104B2 (es) |
BR (1) | BR112015021115B1 (es) |
CA (2) | CA2899041A1 (es) |
CL (2) | CL2015002640A1 (es) |
CR (1) | CR20150510A (es) |
CY (1) | CY1120862T1 (es) |
DK (1) | DK2970257T3 (es) |
DO (1) | DOP2018000026A (es) |
ES (1) | ES2689679T3 (es) |
GT (1) | GT201500248A (es) |
HK (1) | HK1220189A1 (es) |
HR (1) | HRP20181403T8 (es) |
HU (1) | HUE038983T2 (es) |
IL (3) | IL240010B (es) |
LT (1) | LT2970257T (es) |
MX (1) | MX360541B (es) |
MY (1) | MY178821A (es) |
NZ (1) | NZ631701A (es) |
PE (2) | PE20151555A1 (es) |
PL (1) | PL2970257T4 (es) |
PT (1) | PT2970257T (es) |
RS (1) | RS57750B1 (es) |
RU (2) | RU2018127315A (es) |
SG (2) | SG11201507363UA (es) |
SI (1) | SI2970257T1 (es) |
TW (2) | TWI675835B (es) |
UA (1) | UA120035C2 (es) |
UY (1) | UY35406A (es) |
WO (1) | WO2014158528A1 (es) |
ZA (1) | ZA201505203B (es) |
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LT2643322T (lt) | 2010-11-23 | 2018-01-10 | Abbvie Inc. | Apoptozę skatinančio agento druskos ir kristalinės formos |
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