CL2015000717A1 - Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c. - Google Patents

Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c.

Info

Publication number
CL2015000717A1
CL2015000717A1 CL2015000717A CL2015000717A CL2015000717A1 CL 2015000717 A1 CL2015000717 A1 CL 2015000717A1 CL 2015000717 A CL2015000717 A CL 2015000717A CL 2015000717 A CL2015000717 A CL 2015000717A CL 2015000717 A1 CL2015000717 A1 CL 2015000717A1
Authority
CL
Chile
Prior art keywords
disease
niemann
neurodegeneration
salts
treatment
Prior art date
Application number
CL2015000717A
Other languages
English (en)
Spanish (es)
Inventor
Patrick Robert Verhoest
Antonia Friederike Stepan
Ende Christopher William Am
Michael Eric Green
Douglas Scott Johnson
Gregory Wayne Kauffman
Christopher John O'donnell
Nandini Chaturbhai Patel
Martin Youngjin Petterson
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CL2015000717A1 publication Critical patent/CL2015000717A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)
CL2015000717A 2012-09-21 2015-03-20 Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c. CL2015000717A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21

Publications (1)

Publication Number Publication Date
CL2015000717A1 true CL2015000717A1 (es) 2015-06-19

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000717A CL2015000717A1 (es) 2012-09-21 2015-03-20 Compuestos derivados de piridinonas biciclicas y sus sales; composicion farmaceutica que los comprende; y su uso para el tratamiento de la neurodegeneracion y trastornos psiquiatricos, que incluyen enfermedad de alzheimer o enfermedad de niemann-pick tipo c.

Country Status (46)

Country Link
US (3) US8916564B2 (OSRAM)
EP (1) EP2897956B1 (OSRAM)
JP (1) JP5844018B2 (OSRAM)
KR (1) KR101725696B1 (OSRAM)
CN (1) CN104662021B (OSRAM)
AP (1) AP2015008277A0 (OSRAM)
AR (1) AR092628A1 (OSRAM)
AU (1) AU2013319845B2 (OSRAM)
BR (1) BR112015006436A2 (OSRAM)
CA (1) CA2882386C (OSRAM)
CL (1) CL2015000717A1 (OSRAM)
CR (1) CR20150053A (OSRAM)
CU (1) CU20150021A7 (OSRAM)
CY (1) CY1118662T1 (OSRAM)
DK (1) DK2897956T3 (OSRAM)
DO (1) DOP2015000069A (OSRAM)
EA (1) EA026668B1 (OSRAM)
EC (1) ECSP15015594A (OSRAM)
ES (1) ES2609987T3 (OSRAM)
GE (1) GEP201706659B (OSRAM)
GT (1) GT201500069A (OSRAM)
HR (1) HRP20161558T1 (OSRAM)
HU (1) HUE031248T2 (OSRAM)
IL (1) IL237163A (OSRAM)
IN (1) IN2015DN01119A (OSRAM)
LT (1) LT2897956T (OSRAM)
MA (1) MA37886B1 (OSRAM)
MD (1) MD4583B1 (OSRAM)
ME (1) ME02571B (OSRAM)
MX (1) MX360599B (OSRAM)
MY (1) MY181891A (OSRAM)
NI (1) NI201500038A (OSRAM)
NZ (1) NZ704863A (OSRAM)
PE (1) PE20150686A1 (OSRAM)
PH (1) PH12015500376B1 (OSRAM)
PL (1) PL2897956T3 (OSRAM)
PT (1) PT2897956T (OSRAM)
RS (1) RS55426B1 (OSRAM)
SG (1) SG11201501074WA (OSRAM)
SI (1) SI2897956T1 (OSRAM)
TN (1) TN2015000084A1 (OSRAM)
TW (1) TWI500616B (OSRAM)
UA (1) UA110688C2 (OSRAM)
UY (1) UY35039A (OSRAM)
WO (1) WO2014045156A1 (OSRAM)
ZA (1) ZA201501195B (OSRAM)

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PH12022551379A1 (en) 2019-12-06 2023-05-03 Vertex Pharma Substituted tetrahydrofurans as modulators of sodium channels
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
KR20240031300A (ko) 2021-06-04 2024-03-07 버텍스 파마슈티칼스 인코포레이티드 나트륨 채널 조절제로서의 n-(하이드록시알킬 (헤테로)아릴) 테트라하이드로푸란 카르복스아미드
CN114034792B (zh) * 2021-11-09 2024-06-25 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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