PT2897956T - Piridinonas bicíclicas inovadoras - Google Patents

Piridinonas bicíclicas inovadoras

Info

Publication number
PT2897956T
PT2897956T PT137920856T PT13792085T PT2897956T PT 2897956 T PT2897956 T PT 2897956T PT 137920856 T PT137920856 T PT 137920856T PT 13792085 T PT13792085 T PT 13792085T PT 2897956 T PT2897956 T PT 2897956T
Authority
PT
Portugal
Prior art keywords
novel bicyclic
pyridinones
bicyclic pyridinones
novel
bicyclic
Prior art date
Application number
PT137920856T
Other languages
English (en)
Portuguese (pt)
Inventor
William Am Ende Christopher
Eric Green Michael
Scott Johnson Douglas
Wayne Kauffman Gregory
John O'donnell Christopher
Chaturbhai Patel Nandini
Youngjin Pettersson Martin
Friederike Stepan Antonia
Michael Stiff Cory
Subramanyam Chakrapani
Phong Tran Tuan
Robert Verhoest Patrick
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT2897956T publication Critical patent/PT2897956T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Epidemiology (AREA)
PT137920856T 2012-09-21 2013-09-06 Piridinonas bicíclicas inovadoras PT2897956T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21

Publications (1)

Publication Number Publication Date
PT2897956T true PT2897956T (pt) 2017-01-13

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137920856T PT2897956T (pt) 2012-09-21 2013-09-06 Piridinonas bicíclicas inovadoras

Country Status (46)

Country Link
US (3) US8916564B2 (OSRAM)
EP (1) EP2897956B1 (OSRAM)
JP (1) JP5844018B2 (OSRAM)
KR (1) KR101725696B1 (OSRAM)
CN (1) CN104662021B (OSRAM)
AP (1) AP2015008277A0 (OSRAM)
AR (1) AR092628A1 (OSRAM)
AU (1) AU2013319845B2 (OSRAM)
BR (1) BR112015006436A2 (OSRAM)
CA (1) CA2882386C (OSRAM)
CL (1) CL2015000717A1 (OSRAM)
CR (1) CR20150053A (OSRAM)
CU (1) CU20150021A7 (OSRAM)
CY (1) CY1118662T1 (OSRAM)
DK (1) DK2897956T3 (OSRAM)
DO (1) DOP2015000069A (OSRAM)
EA (1) EA026668B1 (OSRAM)
EC (1) ECSP15015594A (OSRAM)
ES (1) ES2609987T3 (OSRAM)
GE (1) GEP201706659B (OSRAM)
GT (1) GT201500069A (OSRAM)
HR (1) HRP20161558T1 (OSRAM)
HU (1) HUE031248T2 (OSRAM)
IL (1) IL237163A (OSRAM)
IN (1) IN2015DN01119A (OSRAM)
LT (1) LT2897956T (OSRAM)
MA (1) MA37886B1 (OSRAM)
MD (1) MD4583B1 (OSRAM)
ME (1) ME02571B (OSRAM)
MX (1) MX360599B (OSRAM)
MY (1) MY181891A (OSRAM)
NI (1) NI201500038A (OSRAM)
NZ (1) NZ704863A (OSRAM)
PE (1) PE20150686A1 (OSRAM)
PH (1) PH12015500376B1 (OSRAM)
PL (1) PL2897956T3 (OSRAM)
PT (1) PT2897956T (OSRAM)
RS (1) RS55426B1 (OSRAM)
SG (1) SG11201501074WA (OSRAM)
SI (1) SI2897956T1 (OSRAM)
TN (1) TN2015000084A1 (OSRAM)
TW (1) TWI500616B (OSRAM)
UA (1) UA110688C2 (OSRAM)
UY (1) UY35039A (OSRAM)
WO (1) WO2014045156A1 (OSRAM)
ZA (1) ZA201501195B (OSRAM)

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US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
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WO2016125048A1 (en) * 2015-02-03 2016-08-11 Pfizer Inc. Novel cyclopropabenzofuranyl pyridopyrazinediones
US9802927B2 (en) 2015-06-10 2017-10-31 Denali Therapeutics, Inc. Oxadiazine compounds and methods of use thereof
JP7018026B2 (ja) 2016-06-16 2022-02-09 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト ヘテロアリールエストロゲン受容体モジュレーター及びその使用
KR20190098998A (ko) 2016-12-16 2019-08-23 파이프라인 테라퓨틱스, 아이엔씨. 달팽이관 시냅스질환의 치료 방법
JP2022504265A (ja) 2018-10-02 2022-01-13 フリークエンシー セラピューティクス インコーポレイテッド 耳治療薬に関する医薬組成物及び方法
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
TW202103692A (zh) 2019-04-08 2021-02-01 美商頻率醫療公司 用於治療聽力損失之組合物及方法
MX2022006865A (es) 2019-12-06 2022-07-11 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio.
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
DK4347031T3 (da) 2021-06-04 2025-12-01 Vertex Pharma N-(hydroxyalkyl-(hetero)aryl)-tetrahydrofuran-carboxamider som modulatorer af natriumkanaler
CN114034792B (zh) * 2021-11-09 2024-06-25 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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