CL2003002353A1 - Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic - Google Patents
Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condicInfo
- Publication number
- CL2003002353A1 CL2003002353A1 CL200302353A CL2003002353A CL2003002353A1 CL 2003002353 A1 CL2003002353 A1 CL 2003002353A1 CL 200302353 A CL200302353 A CL 200302353A CL 2003002353 A CL2003002353 A CL 2003002353A CL 2003002353 A1 CL2003002353 A1 CL 2003002353A1
- Authority
- CL
- Chile
- Prior art keywords
- diaminotriazols
- condic
- autoimmunes
- quinasa
- proteina
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
- NVKAWKQGWWIWPM-ABEVXSGRSA-N 17-β-hydroxy-5-α-Androstan-3-one Chemical compound C1C(=O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC[C@H]21 NVKAWKQGWWIWPM-ABEVXSGRSA-N 0.000 title 1
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000035755 proliferation Effects 0.000 title 1
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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| US42668102P | 2002-11-15 | 2002-11-15 | |
| US44770503P | 2003-02-11 | 2003-02-11 |
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| CL200302353A CL2003002353A1 (es) | 2002-11-15 | 2003-11-14 | Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic |
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| DK113716B (da) * | 1960-07-30 | 1969-04-21 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af 1-[pyrimidinyl-(2)]-guanazolforbindelser eller salte deraf. |
| AU5775198A (en) * | 1997-01-14 | 1998-08-03 | Egis Gyogyszergyar Rt. | 2-(1,2,4-triazole-1-yl)-1,3,4-thiadiazole derivatives having an effect on the c.n.s. and the heart |
| JP2001522853A (ja) * | 1997-11-11 | 2001-11-20 | ファイザー・プロダクツ・インク | 抗癌剤として有用なチエノピリミジンおよびチエノピリジン誘導体 |
| JP2002510033A (ja) * | 1998-01-12 | 2002-04-02 | ザ・サルク・インスティチュート | 二重微小dnaを有する細胞を処理するための組成物およびその処理方法 |
| US6599910B1 (en) | 1998-08-20 | 2003-07-29 | Smithkline Beecham Corporation | Substituted triazole compounds |
| EP1126843A4 (en) * | 1998-10-29 | 2005-06-15 | Bristol Myers Squibb Co | AMINO-CELL DERIVATIVE COMPOUNDS INHIBITORS OF ENZYME IMPDH |
| US6596747B2 (en) * | 1998-10-29 | 2003-07-22 | Bristol-Myers Squibb Company | Compounds derived from an amine nucleus and pharmaceutical compositions comprising same |
| AU782878B2 (en) * | 2000-02-05 | 2005-09-08 | Vertex Pharmaceuticals Incorporated | Pyrazole compositions useful as inhibitors of erk |
| DE60120494T2 (de) * | 2000-12-22 | 2006-12-21 | Ortho-Mcneil Pharmaceutical, Inc. | Substituieten triazoldiamin derivaten und ihre verwendung als kinase inhibitoren |
| DE10123586A1 (de) * | 2001-05-08 | 2002-11-28 | Schering Ag | 3,5-Diamino-1,2,4-triazole als Kinase Inhibitoren |
| CL2003002353A1 (es) * | 2002-11-15 | 2005-02-04 | Vertex Pharma | Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic |
-
2003
- 2003-11-14 CL CL200302353A patent/CL2003002353A1/es unknown
- 2003-11-14 TW TW092132032A patent/TWI335913B/zh not_active IP Right Cessation
- 2003-11-14 AR ARP030104218A patent/AR042052A1/es unknown
- 2003-11-17 NZ NZ540662A patent/NZ540662A/en unknown
- 2003-11-17 PL PL377825A patent/PL377825A1/pl not_active Application Discontinuation
- 2003-11-17 CA CA002505789A patent/CA2505789A1/en not_active Abandoned
- 2003-11-17 BR BR0316350-4A patent/BR0316350A/pt not_active IP Right Cessation
- 2003-11-17 RU RU2005118418/04A patent/RU2350606C2/ru not_active IP Right Cessation
- 2003-11-17 ES ES03789812T patent/ES2318189T3/es not_active Expired - Lifetime
- 2003-11-17 JP JP2004570619A patent/JP4783020B2/ja not_active Expired - Fee Related
- 2003-11-17 AU AU2003294329A patent/AU2003294329B2/en not_active Ceased
- 2003-11-17 EP EP03789812A patent/EP1562589B1/en not_active Expired - Lifetime
- 2003-11-17 US US10/715,111 patent/US7279469B2/en not_active Expired - Fee Related
- 2003-11-17 MX MXPA05005223A patent/MXPA05005223A/es unknown
- 2003-11-17 SI SI200331537T patent/SI1562589T1/sl unknown
- 2003-11-17 KR KR1020057008795A patent/KR20060013480A/ko not_active Ceased
- 2003-11-17 AT AT03789812T patent/ATE419849T1/de active
- 2003-11-17 PT PT03789812T patent/PT1562589E/pt unknown
- 2003-11-17 DE DE60325761T patent/DE60325761D1/de not_active Expired - Lifetime
- 2003-11-17 WO PCT/US2003/036849 patent/WO2004046120A2/en not_active Ceased
- 2003-11-17 DK DK03789812T patent/DK1562589T3/da active
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2005
- 2005-06-10 NO NO20052888A patent/NO20052888L/no not_active Application Discontinuation
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2007
- 2007-07-09 US US11/774,702 patent/US7902239B2/en not_active Expired - Fee Related
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2011
- 2011-04-05 JP JP2011084103A patent/JP2011132263A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05005223A (es) | 2010-09-07 |
| NO20052888L (no) | 2005-08-12 |
| US7902239B2 (en) | 2011-03-08 |
| SI1562589T1 (sl) | 2009-06-30 |
| BR0316350A (pt) | 2005-09-27 |
| NO20052888D0 (no) | 2005-06-10 |
| AU2003294329A1 (en) | 2004-06-15 |
| DE60325761D1 (de) | 2009-02-26 |
| JP2006515313A (ja) | 2006-05-25 |
| US7279469B2 (en) | 2007-10-09 |
| EP1562589B1 (en) | 2009-01-07 |
| EP1562589A2 (en) | 2005-08-17 |
| PT1562589E (pt) | 2009-04-15 |
| RU2005118418A (ru) | 2006-02-10 |
| RU2350606C2 (ru) | 2009-03-27 |
| KR20060013480A (ko) | 2006-02-10 |
| DK1562589T3 (da) | 2009-02-16 |
| JP2011132263A (ja) | 2011-07-07 |
| ES2318189T3 (es) | 2009-05-01 |
| WO2004046120A2 (en) | 2004-06-03 |
| TW200413334A (en) | 2004-08-01 |
| US20080014189A1 (en) | 2008-01-17 |
| TWI335913B (en) | 2011-01-11 |
| WO2004046120A3 (en) | 2004-08-12 |
| AR042052A1 (es) | 2005-06-08 |
| JP4783020B2 (ja) | 2011-09-28 |
| AU2003294329B2 (en) | 2010-04-29 |
| ATE419849T1 (de) | 2009-01-15 |
| US20040214817A1 (en) | 2004-10-28 |
| CA2505789A1 (en) | 2004-06-03 |
| NZ540662A (en) | 2008-04-30 |
| PL377825A1 (pl) | 2006-02-20 |
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