CH639104A5 - Process for the preparation of 1-N-[omega-amino-alpha-hydroxyalkanoyl] kanamycins - Google Patents

Process for the preparation of 1-N-[omega-amino-alpha-hydroxyalkanoyl] kanamycins Download PDF

Info

Publication number
CH639104A5
CH639104A5 CH470278A CH470278A CH639104A5 CH 639104 A5 CH639104 A5 CH 639104A5 CH 470278 A CH470278 A CH 470278A CH 470278 A CH470278 A CH 470278A CH 639104 A5 CH639104 A5 CH 639104A5
Authority
CH
Switzerland
Prior art keywords
kanamycin
acid
amino
mixture
mmol
Prior art date
Application number
CH470278A
Other languages
German (de)
English (en)
Inventor
Martin John Cron
Jeng Shyong Lin
Derek Walker
John Gerard Keil
Mariano Vecchio Ruggeri
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH639104A5 publication Critical patent/CH639104A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH470278A 1977-04-28 1978-04-28 Process for the preparation of 1-N-[omega-amino-alpha-hydroxyalkanoyl] kanamycins CH639104A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79180677A 1977-04-28 1977-04-28
US88858578A 1978-03-20 1978-03-20

Publications (1)

Publication Number Publication Date
CH639104A5 true CH639104A5 (en) 1983-10-31

Family

ID=27121201

Family Applications (1)

Application Number Title Priority Date Filing Date
CH470278A CH639104A5 (en) 1977-04-28 1978-04-28 Process for the preparation of 1-N-[omega-amino-alpha-hydroxyalkanoyl] kanamycins

Country Status (27)

Country Link
JP (1) JPS53149951A (xx)
AR (1) AR218910A1 (xx)
AT (1) AT357675B (xx)
CA (2) CA1100953A (xx)
CH (1) CH639104A5 (xx)
CS (1) CS207607B2 (xx)
CY (1) CY1241A (xx)
DE (2) DE2818822A1 (xx)
DK (2) DK165450C (xx)
EG (1) EG13710A (xx)
ES (1) ES469303A1 (xx)
FI (1) FI781288A (xx)
FR (2) FR2388826A1 (xx)
GB (1) GB1598294A (xx)
HK (1) HK51484A (xx)
IE (2) IE46945B1 (xx)
IT (2) IT1156718B (xx)
KE (1) KE3398A (xx)
LU (1) LU79541A1 (xx)
MY (1) MY8500528A (xx)
NL (1) NL178790C (xx)
NO (2) NO149635C (xx)
PL (1) PL117307B1 (xx)
PT (1) PT67959B (xx)
SE (2) SE447259B (xx)
SG (1) SG22884G (xx)
YU (2) YU102578A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55306A (en) * 1978-04-28 1980-01-05 Bristol Myers Co Manufacture of 11nn*omegaaaminooalphaahydroxy alkanoyl**aminoglycoside antibiotic
TW200303209A (en) * 2002-02-19 2003-09-01 Amato Pharm Prod Ltd Lactic acid derivative
ES2613936T3 (es) 2007-11-21 2017-05-29 Achaogen, Inc. Análogos de aminoglucósido antibacterianos
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin

Also Published As

Publication number Publication date
SE447259B (sv) 1986-11-03
DE2818822C2 (xx) 1989-01-26
NO154697B (no) 1986-08-25
IT7849137A0 (it) 1978-04-28
FR2388827A1 (fr) 1978-11-24
DK172543B1 (da) 1998-12-07
AT357675B (de) 1980-07-25
NL178790C (nl) 1986-05-16
IE47271B1 (en) 1984-02-08
YU102478A (en) 1982-10-31
DK183078A (da) 1978-10-29
NL7804503A (nl) 1978-10-31
DK165450C (da) 1993-04-13
MY8500528A (en) 1985-12-31
FR2388826B1 (xx) 1982-12-10
JPS53149951A (en) 1978-12-27
SE7804973L (sv) 1978-10-29
GB1598294A (en) 1981-09-16
NL178790B (nl) 1985-12-16
CA1105454A (en) 1981-07-21
IE46945B1 (en) 1983-11-16
NO831197L (no) 1978-10-31
IE780842L (en) 1978-10-28
JPS5721277B2 (xx) 1982-05-06
NO154697C (no) 1986-12-03
SG22884G (en) 1985-01-04
CA1100953A (en) 1981-05-12
SE461148B (sv) 1990-01-15
NO149635C (no) 1984-05-23
ATA312778A (de) 1979-12-15
FR2388826A1 (fr) 1978-11-24
CS207607B2 (en) 1981-08-31
LU79541A1 (fr) 1978-11-28
DE2818992A1 (de) 1978-11-23
DE2818822A1 (de) 1978-11-09
KE3398A (en) 1984-06-08
IE780841L (en) 1978-10-28
PT67959A (en) 1978-05-01
ES469303A1 (es) 1979-09-16
DE2818992C2 (xx) 1988-03-17
NO781437L (no) 1978-10-31
FR2388827B1 (xx) 1982-07-09
PT67959B (en) 1980-03-05
SE8305538D0 (sv) 1983-10-07
IT1105500B (it) 1985-11-04
EG13710A (en) 1982-09-30
NO149635B (no) 1984-02-13
YU41590B (en) 1987-12-31
HK51484A (en) 1984-06-22
DK165450B (da) 1992-11-30
DK182978A (da) 1978-10-29
IT1156718B (it) 1987-02-04
SE8305538L (sv) 1983-10-07
PL206457A1 (xx) 1980-03-24
PL117307B1 (en) 1981-07-31
YU102578A (en) 1983-01-21
AR218910A1 (es) 1980-07-15
FI781288A (fi) 1978-10-29
CY1241A (en) 1984-06-29
IT7849136A0 (it) 1978-04-28

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