SE447259B - Forfarande for framstellning av ett 1-n-/l-(-)-omega-amino-alfa-hydroxialkanoyl/kanamycin a eller b - Google Patents

Forfarande for framstellning av ett 1-n-/l-(-)-omega-amino-alfa-hydroxialkanoyl/kanamycin a eller b

Info

Publication number
SE447259B
SE447259B SE7804973A SE7804973A SE447259B SE 447259 B SE447259 B SE 447259B SE 7804973 A SE7804973 A SE 7804973A SE 7804973 A SE7804973 A SE 7804973A SE 447259 B SE447259 B SE 447259B
Authority
SE
Sweden
Prior art keywords
kanamycin
acid
mmol
silyl
mixture
Prior art date
Application number
SE7804973A
Other languages
English (en)
Swedish (sv)
Other versions
SE7804973L (sv
Inventor
Martin John Cron
John Gerard Keil
Jeng Shyong Lin
Mariano Vecchio Ruggeri
Derek Walker
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7804973L publication Critical patent/SE7804973L/xx
Publication of SE447259B publication Critical patent/SE447259B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7804973A 1977-04-28 1978-04-28 Forfarande for framstellning av ett 1-n-/l-(-)-omega-amino-alfa-hydroxialkanoyl/kanamycin a eller b SE447259B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79180677A 1977-04-28 1977-04-28
US88858578A 1978-03-20 1978-03-20

Publications (2)

Publication Number Publication Date
SE7804973L SE7804973L (sv) 1978-10-29
SE447259B true SE447259B (sv) 1986-11-03

Family

ID=27121201

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7804973A SE447259B (sv) 1977-04-28 1978-04-28 Forfarande for framstellning av ett 1-n-/l-(-)-omega-amino-alfa-hydroxialkanoyl/kanamycin a eller b
SE8305538A SE461148B (sv) 1977-04-28 1983-10-07 Polysilylerat kanamycin a eller b derivat

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8305538A SE461148B (sv) 1977-04-28 1983-10-07 Polysilylerat kanamycin a eller b derivat

Country Status (27)

Country Link
JP (1) JPS53149951A (xx)
AR (1) AR218910A1 (xx)
AT (1) AT357675B (xx)
CA (2) CA1100953A (xx)
CH (1) CH639104A5 (xx)
CS (1) CS207607B2 (xx)
CY (1) CY1241A (xx)
DE (2) DE2818822A1 (xx)
DK (2) DK165450C (xx)
EG (1) EG13710A (xx)
ES (1) ES469303A1 (xx)
FI (1) FI781288A (xx)
FR (2) FR2388826A1 (xx)
GB (1) GB1598294A (xx)
HK (1) HK51484A (xx)
IE (2) IE46945B1 (xx)
IT (2) IT1156718B (xx)
KE (1) KE3398A (xx)
LU (1) LU79541A1 (xx)
MY (1) MY8500528A (xx)
NL (1) NL178790C (xx)
NO (2) NO149635C (xx)
PL (1) PL117307B1 (xx)
PT (1) PT67959B (xx)
SE (2) SE447259B (xx)
SG (1) SG22884G (xx)
YU (2) YU102578A (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55306A (en) * 1978-04-28 1980-01-05 Bristol Myers Co Manufacture of 11nn*omegaaaminooalphaahydroxy alkanoyl**aminoglycoside antibiotic
TW200303209A (en) * 2002-02-19 2003-09-01 Amato Pharm Prod Ltd Lactic acid derivative
ES2613936T3 (es) 2007-11-21 2017-05-29 Achaogen, Inc. Análogos de aminoglucósido antibacterianos
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132757A2 (en) * 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin

Also Published As

Publication number Publication date
DE2818822C2 (xx) 1989-01-26
NO154697B (no) 1986-08-25
IT7849137A0 (it) 1978-04-28
FR2388827A1 (fr) 1978-11-24
DK172543B1 (da) 1998-12-07
AT357675B (de) 1980-07-25
NL178790C (nl) 1986-05-16
IE47271B1 (en) 1984-02-08
YU102478A (en) 1982-10-31
DK183078A (da) 1978-10-29
NL7804503A (nl) 1978-10-31
DK165450C (da) 1993-04-13
MY8500528A (en) 1985-12-31
FR2388826B1 (xx) 1982-12-10
JPS53149951A (en) 1978-12-27
SE7804973L (sv) 1978-10-29
GB1598294A (en) 1981-09-16
NL178790B (nl) 1985-12-16
CA1105454A (en) 1981-07-21
IE46945B1 (en) 1983-11-16
NO831197L (no) 1978-10-31
IE780842L (en) 1978-10-28
JPS5721277B2 (xx) 1982-05-06
NO154697C (no) 1986-12-03
SG22884G (en) 1985-01-04
CA1100953A (en) 1981-05-12
SE461148B (sv) 1990-01-15
NO149635C (no) 1984-05-23
CH639104A5 (en) 1983-10-31
ATA312778A (de) 1979-12-15
FR2388826A1 (fr) 1978-11-24
CS207607B2 (en) 1981-08-31
LU79541A1 (fr) 1978-11-28
DE2818992A1 (de) 1978-11-23
DE2818822A1 (de) 1978-11-09
KE3398A (en) 1984-06-08
IE780841L (en) 1978-10-28
PT67959A (en) 1978-05-01
ES469303A1 (es) 1979-09-16
DE2818992C2 (xx) 1988-03-17
NO781437L (no) 1978-10-31
FR2388827B1 (xx) 1982-07-09
PT67959B (en) 1980-03-05
SE8305538D0 (sv) 1983-10-07
IT1105500B (it) 1985-11-04
EG13710A (en) 1982-09-30
NO149635B (no) 1984-02-13
YU41590B (en) 1987-12-31
HK51484A (en) 1984-06-22
DK165450B (da) 1992-11-30
DK182978A (da) 1978-10-29
IT1156718B (it) 1987-02-04
SE8305538L (sv) 1983-10-07
PL206457A1 (xx) 1980-03-24
PL117307B1 (en) 1981-07-31
YU102578A (en) 1983-01-21
AR218910A1 (es) 1980-07-15
FI781288A (fi) 1978-10-29
CY1241A (en) 1984-06-29
IT7849136A0 (it) 1978-04-28

Similar Documents

Publication Publication Date Title
US4347354A (en) Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom
US4424343A (en) Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products
US4065615A (en) Deoxyaminoglycoside antibiotic derivatives
DE2332485C2 (de) Gentamicin C1-derivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
SE447259B (sv) Forfarande for framstellning av ett 1-n-/l-(-)-omega-amino-alfa-hydroxialkanoyl/kanamycin a eller b
Kusumoto et al. Synthesis of streptolidine (roseonine, geamine)
DE2322576A1 (de) Antibiotische derivate und verfahren zu deren herstellung
DE2423591C3 (de) 1-N-Isoserylkanamycine, Verfahren zu ihrer Herstellung und solche Verbindungen enthaltende Arzneimittel
DE2855348A1 (de) Fortimycin a-derivate und ihre verwendung
GB1600457A (en) Process for the preparation of 1-n-acylaminoglycosides
DE3044970A1 (de) 3',4'-dideoxyparomomycin, verfahren zu dessen herstellung und diese verbindung enthaltende arzneimittel
CA1046513A (en) Antibiotic derivatives
DE1163337B (de) Verfahren zur Herstellung von Trihydroxamsaeuren
DE2352361A1 (de) Antibiotische derivate
EP0252030B1 (en) Derivatives of l-amino acyl l-carnitine, process for their preparation and pharmaceutical compositions having hepatoprotecting activity containing same
DE2458921B2 (de) N-(2-hydroxy-4-aminobutyryl)-derivate des antibiotikums xk-62-2, ihre salze, verfahren zu ihrer herstellung und arzneimittel
US4220643A (en) Nitrosourea pentose compounds
KR820000276B1 (ko) 1-N-[W-아미노-α-하이드록시알카노일)가나마이신류의 제조방법
DE3142401A1 (de) Aprosamin-derivate und diese verbindungen enthaltende arzneimittel
CA1081693A (en) Kanamycin c derivatives
IT8209478A1 (it) Kanamicine 2'-modificate e produzione di queste
DK167687B1 (da) Derivat af kanamycin a eller b til anvendelse ved fremstilling af 1-n-oeomega-amino-alfa-hydroxyalkanoylaakanamycin a eller b
SE451326B (sv) Sett att framstella l-4-amino-2-hydroxismorsyra eller l-2,4-diaminosmorsyra
US6235775B1 (en) Acetone adduct of fungicidal V-28-3M
JPS58198497A (ja) 新規アミノ配糖体及びその製法

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7804973-1

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7804973-1

Format of ref document f/p: F