CH613963A5 - - Google Patents

Info

Publication number
CH613963A5
CH613963A5 CH1002475A CH1002475A CH613963A5 CH 613963 A5 CH613963 A5 CH 613963A5 CH 1002475 A CH1002475 A CH 1002475A CH 1002475 A CH1002475 A CH 1002475A CH 613963 A5 CH613963 A5 CH 613963A5
Authority
CH
Switzerland
Application number
CH1002475A
Inventor
Herbert Dr Merz
Adolf Dr Langbein
Gerhard Dr Walther
Kalus Dr Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of CH613963A5 publication Critical patent/CH613963A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1002475A 1974-08-05 1975-07-31 CH613963A5 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437610A DE2437610A1 (de) 1974-08-05 1974-08-05 Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CH613963A5 true CH613963A5 (pl) 1979-10-31

Family

ID=5922448

Family Applications (7)

Application Number Title Priority Date Filing Date
CH1002475A CH613963A5 (pl) 1974-08-05 1975-07-31
CH393679A CH615680A5 (pl) 1974-08-05 1979-04-26
CH393179A CH615677A5 (pl) 1974-08-05 1979-04-26
CH393279A CH615678A5 (pl) 1974-08-05 1979-04-26
CH393379A CH616420A5 (pl) 1974-08-05 1979-04-26
CH393579A CH616421A5 (pl) 1974-08-05 1979-04-26
CH393479A CH615679A5 (pl) 1974-08-05 1979-04-26

Family Applications After (6)

Application Number Title Priority Date Filing Date
CH393679A CH615680A5 (pl) 1974-08-05 1979-04-26
CH393179A CH615677A5 (pl) 1974-08-05 1979-04-26
CH393279A CH615678A5 (pl) 1974-08-05 1979-04-26
CH393379A CH616420A5 (pl) 1974-08-05 1979-04-26
CH393579A CH616421A5 (pl) 1974-08-05 1979-04-26
CH393479A CH615679A5 (pl) 1974-08-05 1979-04-26

Country Status (27)

Country Link
US (1) US3982005A (pl)
JP (1) JPS60358B2 (pl)
AT (1) AT348140B (pl)
BE (1) BE832099R (pl)
BG (3) BG25088A3 (pl)
CA (1) CA1049008A (pl)
CH (7) CH613963A5 (pl)
CS (1) CS189717B2 (pl)
DD (1) DD122685A5 (pl)
DE (1) DE2437610A1 (pl)
DK (1) DK138992C (pl)
ES (6) ES452768A1 (pl)
FI (1) FI63229C (pl)
FR (1) FR2320096A2 (pl)
GB (1) GB1513950A (pl)
HU (1) HU177952B (pl)
IE (1) IE42216B1 (pl)
IL (1) IL47860A (pl)
LU (1) LU73138A1 (pl)
NL (1) NL7509249A (pl)
NO (1) NO143460C (pl)
PH (1) PH13687A (pl)
PL (3) PL99838B1 (pl)
RO (3) RO67390A (pl)
SE (1) SE425392B (pl)
SU (3) SU591147A3 (pl)
ZA (1) ZA754997B (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JPS5636521A (en) * 1979-08-31 1981-04-09 Shin Etsu Chem Co Ltd Production of alkenyloxy group-containing organopolysiloxane
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1のサイクリックインヒビター
CA2704628C (en) 2007-11-16 2016-11-29 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2687525B1 (en) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) * 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体
KR20230112134A (ko) 2020-11-26 2023-07-26 신에쓰 가가꾸 고교 가부시끼가이샤 실온경화성 오르가노폴리실록산 조성물 및 물품 그리고 가수분해성 오르가노실란 화합물 및 그 제조 방법
WO2023032745A1 (ja) 2021-09-03 2023-03-09 信越化学工業株式会社 オルガノポリシロキサン化合物、室温硬化性オルガノポリシロキサン組成物、及び物品

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (pl) * 1958-09-22
US3700734A (en) * 1969-01-23 1972-10-24 Merck & Co Inc 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
DE2105743C3 (de) * 1971-02-08 1979-11-29 Boehringer Sohn Ingelheim 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
CS166804B2 (pl) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2200596A1 (de) * 1972-01-07 1973-07-12 Boehringer Sohn Ingelheim N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
HU177952B (en) 1982-02-28
CH615678A5 (pl) 1980-02-15
AT348140B (de) 1979-01-25
CH615679A5 (pl) 1980-02-15
ATA523775A (de) 1978-06-15
DE2437610A1 (de) 1976-02-26
US3982005A (en) 1976-09-21
ES452766A1 (es) 1977-10-01
IL47860A (en) 1979-01-31
LU73138A1 (pl) 1977-04-13
JPS5139673A (en) 1976-04-02
PL99819B1 (pl) 1978-08-31
CS189717B2 (en) 1979-04-30
IE42216L (en) 1976-02-05
SU587859A3 (ru) 1978-01-05
SU591147A3 (ru) 1978-01-30
ES452768A1 (es) 1977-10-01
SE425392B (sv) 1982-09-27
RO72735A (ro) 1982-09-09
DK138992C (da) 1979-04-30
DK138992B (da) 1978-11-27
NO143460C (no) 1981-02-18
JPS60358B2 (ja) 1985-01-07
ES452763A1 (es) 1977-10-01
CH616421A5 (pl) 1980-03-31
FI63229B (fi) 1983-01-31
FI752211A (pl) 1976-02-06
BG25090A3 (en) 1978-07-12
SU587858A3 (ru) 1978-01-05
BG25088A3 (en) 1978-07-12
CA1049008A (en) 1979-02-20
DK352875A (da) 1976-02-06
CH615680A5 (pl) 1980-02-15
FR2320096B2 (pl) 1978-09-01
NL7509249A (nl) 1976-02-09
FR2320096A2 (fr) 1977-03-04
RO72736A (ro) 1982-09-09
ES452764A1 (es) 1977-10-16
PH13687A (en) 1980-09-01
RO67390A (ro) 1981-06-30
PL99838B1 (pl) 1978-08-31
ZA754997B (en) 1977-04-27
DD122685A5 (pl) 1976-10-20
GB1513950A (en) 1978-06-14
NO143460B (no) 1980-11-10
NO752731L (pl) 1976-02-06
SE7508789L (sv) 1976-02-10
FI63229C (fi) 1983-05-10
ES452765A1 (es) 1977-10-16
IL47860A0 (en) 1975-11-25
PL99816B1 (pl) 1978-08-31
AU8364675A (en) 1977-02-10
BG25089A3 (en) 1978-07-12
CH615677A5 (pl) 1980-02-15
CH616420A5 (pl) 1980-03-31
BE832099R (fr) 1976-02-04
ES452767A1 (es) 1977-10-01
IE42216B1 (en) 1980-07-02

Similar Documents

Publication Publication Date Title
FR2282815B2 (pl)
NO752731L (pl)
JPS50101771A (pl)
FR2259507B1 (pl)
FR2293468B1 (pl)
FR2277091B1 (pl)
FR2275153B1 (pl)
DE2462558C2 (pl)
FR2267598A1 (pl)
FR2286088B1 (pl)
JPS50104461A (pl)
JPS50101997A (pl)
JPS50102794A (pl)
FR2296908B1 (pl)
JPS50103560U (pl)
DK158475A (pl)
BG21634A1 (pl)
CH1727074A4 (pl)
CH603017A5 (pl)
CH597793A5 (pl)
CH593781A5 (pl)
CH569666A5 (pl)
CH569220A5 (pl)
CH568539A5 (pl)
CH566915A5 (pl)

Legal Events

Date Code Title Description
PL Patent ceased