CH498834A - Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid - Google Patents
Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylididInfo
- Publication number
- CH498834A CH498834A CH733568A CH733568A CH498834A CH 498834 A CH498834 A CH 498834A CH 733568 A CH733568 A CH 733568A CH 733568 A CH733568 A CH 733568A CH 498834 A CH498834 A CH 498834A
- Authority
- CH
- Switzerland
- Prior art keywords
- pipecoloxylidide
- laevo
- butyl
- dextro
- tartrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63927767A | 1967-05-18 | 1967-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH498834A true CH498834A (de) | 1970-11-15 |
Family
ID=24563449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH733568A CH498834A (de) | 1967-05-18 | 1968-05-17 | Verfahren zur Herstellung von laevo-1-n-Butyl-2',6'-pipecoloxylidid |
Country Status (13)
| Country | Link |
|---|---|
| AT (2) | AT286298B (fi) |
| BE (1) | BE715188A (fi) |
| CH (1) | CH498834A (fi) |
| DE (1) | DE1770408C3 (fi) |
| DK (1) | DK129234B (fi) |
| ES (1) | ES354352A1 (fi) |
| FI (1) | FI50333C (fi) |
| FR (2) | FR1583872A (fi) |
| GB (1) | GB1180712A (fi) |
| IL (1) | IL29958A (fi) |
| NL (1) | NL6806995A (fi) |
| NO (1) | NO124540B (fi) |
| SE (1) | SE341404B (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0151110B1 (en) * | 1983-08-01 | 1989-03-01 | Astra Läkemedel Aktiebolag | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
| SE451840B (sv) * | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
| DE69531356T2 (de) * | 1994-10-25 | 2004-05-27 | Darwin Discovery Ltd., Slough | Kristallisierung von levobupivacaine und deren analogen |
| SE9501808D0 (sv) * | 1995-05-16 | 1995-05-16 | Astra Ab | New process |
| KR100844336B1 (ko) * | 2007-01-16 | 2008-07-07 | 하나제약 주식회사 | 레보부피바카인 및 이의 염산염의 신규한 제조방법 |
| WO2014009964A1 (en) * | 2012-07-11 | 2014-01-16 | Neon Laboratories Limited | Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide |
| CN105315196A (zh) * | 2015-11-28 | 2016-02-10 | 山东齐都药业有限公司 | 一种高纯度盐酸左布比卡因精制方法 |
| CN109896992A (zh) * | 2017-12-08 | 2019-06-18 | 武汉软件工程职业学院 | 制备离子液体的方法及其应用 |
-
1968
- 1968-05-02 SE SE05905/68A patent/SE341404B/xx unknown
- 1968-05-07 IL IL29958A patent/IL29958A/xx unknown
- 1968-05-10 GB GB22420/68A patent/GB1180712A/en not_active Expired
- 1968-05-10 NO NO1819/68A patent/NO124540B/no unknown
- 1968-05-14 DE DE1770408A patent/DE1770408C3/de not_active Expired
- 1968-05-15 BE BE715188D patent/BE715188A/xx unknown
- 1968-05-16 ES ES354352A patent/ES354352A1/es not_active Expired
- 1968-05-16 DK DK226968AA patent/DK129234B/da unknown
- 1968-05-17 FI FI681394A patent/FI50333C/fi active
- 1968-05-17 FR FR1583872D patent/FR1583872A/fr not_active Expired
- 1968-05-17 AT AT1097469A patent/AT286298B/de not_active IP Right Cessation
- 1968-05-17 AT AT475368A patent/AT284843B/de not_active IP Right Cessation
- 1968-05-17 NL NL6806995A patent/NL6806995A/xx unknown
- 1968-05-17 CH CH733568A patent/CH498834A/de not_active IP Right Cessation
- 1968-08-16 FR FR163282A patent/FR8160M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL29958A0 (en) | 1968-07-25 |
| FR1583872A (fi) | 1969-12-05 |
| DE1770408A1 (de) | 1971-10-21 |
| DK129234C (fi) | 1975-02-03 |
| BE715188A (fi) | 1968-09-30 |
| AT286298B (de) | 1970-12-10 |
| AT284843B (de) | 1970-09-25 |
| DE1770408C3 (de) | 1974-11-07 |
| IL29958A (en) | 1971-04-28 |
| NL6806995A (fi) | 1968-11-19 |
| SE341404B (fi) | 1971-12-27 |
| ES354352A1 (es) | 1969-11-01 |
| GB1180712A (en) | 1970-02-11 |
| FI50333B (fi) | 1975-10-31 |
| FR8160M (fi) | 1970-08-24 |
| FI50333C (fi) | 1976-02-10 |
| DE1770408B2 (fi) | 1974-04-11 |
| NO124540B (fi) | 1972-05-02 |
| DK129234B (da) | 1974-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |