GB1180712A - Novel levo-1-n-butyl-2',6'-pipecoloxylidide and the Preparation Thereof - Google Patents
Novel levo-1-n-butyl-2',6'-pipecoloxylidide and the Preparation ThereofInfo
- Publication number
- GB1180712A GB1180712A GB22420/68A GB2242068A GB1180712A GB 1180712 A GB1180712 A GB 1180712A GB 22420/68 A GB22420/68 A GB 22420/68A GB 2242068 A GB2242068 A GB 2242068A GB 1180712 A GB1180712 A GB 1180712A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pipecoloxylidide
- butyl
- levo
- tartrate
- dextro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63927767A | 1967-05-18 | 1967-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1180712A true GB1180712A (en) | 1970-02-11 |
Family
ID=24563449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB22420/68A Expired GB1180712A (en) | 1967-05-18 | 1968-05-10 | Novel levo-1-n-butyl-2',6'-pipecoloxylidide and the Preparation Thereof |
Country Status (13)
Country | Link |
---|---|
AT (2) | AT286298B (fi) |
BE (1) | BE715188A (fi) |
CH (1) | CH498834A (fi) |
DE (1) | DE1770408C3 (fi) |
DK (1) | DK129234B (fi) |
ES (1) | ES354352A1 (fi) |
FI (1) | FI50333C (fi) |
FR (2) | FR1583872A (fi) |
GB (1) | GB1180712A (fi) |
IL (1) | IL29958A (fi) |
NL (1) | NL6806995A (fi) |
NO (1) | NO124540B (fi) |
SE (1) | SE341404B (fi) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996036606A1 (en) * | 1995-05-16 | 1996-11-21 | Astra Aktiebolag (Publ) | New process for the preparation of ropivacaine hydrochloride monohydrate |
US5994548A (en) * | 1994-10-25 | 1999-11-30 | Darwin Discovery Ltd. | Crystallisation of levibupivacaine and analogues thereof |
KR100844336B1 (ko) * | 2007-01-16 | 2008-07-07 | 하나제약 주식회사 | 레보부피바카인 및 이의 염산염의 신규한 제조방법 |
WO2014009964A1 (en) * | 2012-07-11 | 2014-01-16 | Neon Laboratories Limited | Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide |
CN105315196A (zh) * | 2015-11-28 | 2016-02-10 | 山东齐都药业有限公司 | 一种高纯度盐酸左布比卡因精制方法 |
CN109896992A (zh) * | 2017-12-08 | 2019-06-18 | 武汉软件工程职业学院 | 制备离子液体的方法及其应用 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0151110B1 (en) * | 1983-08-01 | 1989-03-01 | Astra Läkemedel Aktiebolag | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
SE451840B (sv) * | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
-
1968
- 1968-05-02 SE SE05905/68A patent/SE341404B/xx unknown
- 1968-05-07 IL IL29958A patent/IL29958A/xx unknown
- 1968-05-10 NO NO1819/68A patent/NO124540B/no unknown
- 1968-05-10 GB GB22420/68A patent/GB1180712A/en not_active Expired
- 1968-05-14 DE DE1770408A patent/DE1770408C3/de not_active Expired
- 1968-05-15 BE BE715188D patent/BE715188A/xx unknown
- 1968-05-16 ES ES354352A patent/ES354352A1/es not_active Expired
- 1968-05-16 DK DK226968AA patent/DK129234B/da unknown
- 1968-05-17 NL NL6806995A patent/NL6806995A/xx unknown
- 1968-05-17 AT AT1097469A patent/AT286298B/de not_active IP Right Cessation
- 1968-05-17 CH CH733568A patent/CH498834A/de not_active IP Right Cessation
- 1968-05-17 AT AT475368A patent/AT284843B/de not_active IP Right Cessation
- 1968-05-17 FR FR1583872D patent/FR1583872A/fr not_active Expired
- 1968-05-17 FI FI681394A patent/FI50333C/fi active
- 1968-08-16 FR FR163282A patent/FR8160M/fr not_active Expired
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994548A (en) * | 1994-10-25 | 1999-11-30 | Darwin Discovery Ltd. | Crystallisation of levibupivacaine and analogues thereof |
WO1996036606A1 (en) * | 1995-05-16 | 1996-11-21 | Astra Aktiebolag (Publ) | New process for the preparation of ropivacaine hydrochloride monohydrate |
US5959112A (en) * | 1995-05-16 | 1999-09-28 | Astra Aktiebolag | Process for the preparation of ropivacaine hydrochloride monohydrate |
CN1121388C (zh) * | 1995-05-16 | 2003-09-17 | 阿斯特拉公司 | 制备罗哌卡因盐酸盐—水合物的新方法 |
KR100844336B1 (ko) * | 2007-01-16 | 2008-07-07 | 하나제약 주식회사 | 레보부피바카인 및 이의 염산염의 신규한 제조방법 |
WO2014009964A1 (en) * | 2012-07-11 | 2014-01-16 | Neon Laboratories Limited | Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide |
CN105315196A (zh) * | 2015-11-28 | 2016-02-10 | 山东齐都药业有限公司 | 一种高纯度盐酸左布比卡因精制方法 |
CN109896992A (zh) * | 2017-12-08 | 2019-06-18 | 武汉软件工程职业学院 | 制备离子液体的方法及其应用 |
Also Published As
Publication number | Publication date |
---|---|
ES354352A1 (es) | 1969-11-01 |
FR1583872A (fi) | 1969-12-05 |
IL29958A (en) | 1971-04-28 |
NL6806995A (fi) | 1968-11-19 |
CH498834A (de) | 1970-11-15 |
BE715188A (fi) | 1968-09-30 |
AT286298B (de) | 1970-12-10 |
AT284843B (de) | 1970-09-25 |
DE1770408A1 (de) | 1971-10-21 |
FI50333C (fi) | 1976-02-10 |
FI50333B (fi) | 1975-10-31 |
DK129234C (fi) | 1975-02-03 |
DE1770408B2 (fi) | 1974-04-11 |
IL29958A0 (en) | 1968-07-25 |
DE1770408C3 (de) | 1974-11-07 |
NO124540B (fi) | 1972-05-02 |
DK129234B (da) | 1974-09-16 |
FR8160M (fi) | 1970-08-24 |
SE341404B (fi) | 1971-12-27 |
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