GB1180250A - Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same - Google Patents
Improvements in or relating to New But-2-Yne Derivative and Process for Preparing sameInfo
- Publication number
- GB1180250A GB1180250A GB58879/67A GB5887967A GB1180250A GB 1180250 A GB1180250 A GB 1180250A GB 58879/67 A GB58879/67 A GB 58879/67A GB 5887967 A GB5887967 A GB 5887967A GB 1180250 A GB1180250 A GB 1180250A
- Authority
- GB
- United Kingdom
- Prior art keywords
- succinimide
- propargyl
- relating
- new
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
1,180,250. 1 (2,5 - Dioxo - 1 - pyrrolidino)- 4 - perhydroazepino) - but - 2 - yne. LABORATOIRES AUCLAIR. 28 Dec., 1967 [6 Jan., 1967], No. 58879/67. Heading C2C. The novel compound of formula and acid addition salts thereof are prepared by reaction of N-propargyl-succinimide and hexamethylenimine with formaldehyde or trioxymethylene optionally followed by salt formation. N - propargyl - succinimide is prepared by reaction of succinimide and a propargyl ester. Pharmaceutical compositions having an effect on the central nervous system particularly as an anticholinergenic agent and in conventional forms for oral or parenteral administration comprise an above novel compound or a salt thereof and one or more carriers or diluents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR90164A FR6369M (en) | 1967-01-06 | 1967-01-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1180250A true GB1180250A (en) | 1970-02-04 |
Family
ID=8623457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB58879/67A Expired GB1180250A (en) | 1967-01-06 | 1967-12-28 | Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same |
Country Status (8)
Country | Link |
---|---|
AT (1) | AT273091B (en) |
BE (1) | BE708558A (en) |
CH (1) | CH484925A (en) |
DE (1) | DE1695379A1 (en) |
ES (1) | ES348973A1 (en) |
FR (1) | FR6369M (en) |
GB (1) | GB1180250A (en) |
NL (1) | NL6800223A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1314557A (en) * | 1969-12-02 | 1973-04-26 | Astra Laekemedel Ab | Oxotremorine antagonists and methods for their preparation |
-
1967
- 1967-01-06 FR FR90164A patent/FR6369M/fr not_active Expired
- 1967-12-27 BE BE708558D patent/BE708558A/xx unknown
- 1967-12-28 GB GB58879/67A patent/GB1180250A/en not_active Expired
- 1967-12-29 CH CH1829667A patent/CH484925A/en not_active IP Right Cessation
-
1968
- 1968-01-05 AT AT12468A patent/AT273091B/en active
- 1968-01-05 NL NL6800223A patent/NL6800223A/xx unknown
- 1968-01-05 ES ES348973A patent/ES348973A1/en not_active Expired
- 1968-01-05 DE DE19681695379 patent/DE1695379A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
DE1695379A1 (en) | 1970-09-10 |
BE708558A (en) | 1968-05-02 |
AT273091B (en) | 1969-07-25 |
CH484925A (en) | 1970-01-31 |
FR6369M (en) | 1968-10-14 |
ES348973A1 (en) | 1969-03-16 |
NL6800223A (en) | 1968-07-08 |
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