ES348973A1 - Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same - Google Patents

Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same

Info

Publication number
ES348973A1
ES348973A1 ES348973A ES348973A ES348973A1 ES 348973 A1 ES348973 A1 ES 348973A1 ES 348973 A ES348973 A ES 348973A ES 348973 A ES348973 A ES 348973A ES 348973 A1 ES348973 A1 ES 348973A1
Authority
ES
Spain
Prior art keywords
succinimide
propargyl
relating
new
preparing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES348973A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LAB AUCLAIR
Original Assignee
LAB AUCLAIR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LAB AUCLAIR filed Critical LAB AUCLAIR
Publication of ES348973A1 publication Critical patent/ES348973A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

The novel compound of formula and acid addition salts thereof are prepared by reaction of N-propargyl-succinimide and hexamethylenimine with formaldehyde or trioxymethylene optionally followed by salt formation. N - propargyl - succinimide is prepared by reaction of succinimide and a propargyl ester. Pharmaceutical compositions having an effect on the central nervous system particularly as an anticholinergenic agent and in conventional forms for oral or parenteral administration comprise an above novel compound or a salt thereof and one or more carriers or diluents.
ES348973A 1967-01-06 1968-01-05 Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same Expired ES348973A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR90164A FR6369M (en) 1967-01-06 1967-01-06

Publications (1)

Publication Number Publication Date
ES348973A1 true ES348973A1 (en) 1969-03-16

Family

ID=8623457

Family Applications (1)

Application Number Title Priority Date Filing Date
ES348973A Expired ES348973A1 (en) 1967-01-06 1968-01-05 Improvements in or relating to New But-2-Yne Derivative and Process for Preparing same

Country Status (8)

Country Link
AT (1) AT273091B (en)
BE (1) BE708558A (en)
CH (1) CH484925A (en)
DE (1) DE1695379A1 (en)
ES (1) ES348973A1 (en)
FR (1) FR6369M (en)
GB (1) GB1180250A (en)
NL (1) NL6800223A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1314557A (en) * 1969-12-02 1973-04-26 Astra Laekemedel Ab Oxotremorine antagonists and methods for their preparation

Also Published As

Publication number Publication date
AT273091B (en) 1969-07-25
CH484925A (en) 1970-01-31
BE708558A (en) 1968-05-02
DE1695379A1 (en) 1970-09-10
FR6369M (en) 1968-10-14
NL6800223A (en) 1968-07-08
GB1180250A (en) 1970-02-04

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