ES354352A1 - Un procedimiento para la preparacion de levo - 1 - n-butil-2',6'-pipecoloxiliduro. - Google Patents
Un procedimiento para la preparacion de levo - 1 - n-butil-2',6'-pipecoloxiliduro.Info
- Publication number
- ES354352A1 ES354352A1 ES354352A ES354352A ES354352A1 ES 354352 A1 ES354352 A1 ES 354352A1 ES 354352 A ES354352 A ES 354352A ES 354352 A ES354352 A ES 354352A ES 354352 A1 ES354352 A1 ES 354352A1
- Authority
- ES
- Spain
- Prior art keywords
- pipecoloxylidide
- butyl
- tartrate
- levo
- dextro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63927767A | 1967-05-18 | 1967-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES354352A1 true ES354352A1 (es) | 1969-11-01 |
Family
ID=24563449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES354352A Expired ES354352A1 (es) | 1967-05-18 | 1968-05-16 | Un procedimiento para la preparacion de levo - 1 - n-butil-2',6'-pipecoloxiliduro. |
Country Status (13)
Country | Link |
---|---|
AT (2) | AT284843B (fi) |
BE (1) | BE715188A (fi) |
CH (1) | CH498834A (fi) |
DE (1) | DE1770408C3 (fi) |
DK (1) | DK129234B (fi) |
ES (1) | ES354352A1 (fi) |
FI (1) | FI50333C (fi) |
FR (2) | FR1583872A (fi) |
GB (1) | GB1180712A (fi) |
IL (1) | IL29958A (fi) |
NL (1) | NL6806995A (fi) |
NO (1) | NO124540B (fi) |
SE (1) | SE341404B (fi) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3379266D1 (en) * | 1983-08-01 | 1989-04-06 | Astra Laekemedel Ab | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
SE451840B (sv) * | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
US5994548A (en) * | 1994-10-25 | 1999-11-30 | Darwin Discovery Ltd. | Crystallisation of levibupivacaine and analogues thereof |
SE9501808D0 (sv) * | 1995-05-16 | 1995-05-16 | Astra Ab | New process |
KR100844336B1 (ko) * | 2007-01-16 | 2008-07-07 | 하나제약 주식회사 | 레보부피바카인 및 이의 염산염의 신규한 제조방법 |
WO2014009964A1 (en) * | 2012-07-11 | 2014-01-16 | Neon Laboratories Limited | Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide |
CN105315196A (zh) * | 2015-11-28 | 2016-02-10 | 山东齐都药业有限公司 | 一种高纯度盐酸左布比卡因精制方法 |
CN109896992A (zh) * | 2017-12-08 | 2019-06-18 | 武汉软件工程职业学院 | 制备离子液体的方法及其应用 |
-
1968
- 1968-05-02 SE SE05905/68A patent/SE341404B/xx unknown
- 1968-05-07 IL IL29958A patent/IL29958A/xx unknown
- 1968-05-10 NO NO1819/68A patent/NO124540B/no unknown
- 1968-05-10 GB GB22420/68A patent/GB1180712A/en not_active Expired
- 1968-05-14 DE DE1770408A patent/DE1770408C3/de not_active Expired
- 1968-05-15 BE BE715188D patent/BE715188A/xx unknown
- 1968-05-16 DK DK226968AA patent/DK129234B/da unknown
- 1968-05-16 ES ES354352A patent/ES354352A1/es not_active Expired
- 1968-05-17 AT AT475368A patent/AT284843B/de not_active IP Right Cessation
- 1968-05-17 FI FI681394A patent/FI50333C/fi active
- 1968-05-17 AT AT1097469A patent/AT286298B/de not_active IP Right Cessation
- 1968-05-17 FR FR1583872D patent/FR1583872A/fr not_active Expired
- 1968-05-17 CH CH733568A patent/CH498834A/de not_active IP Right Cessation
- 1968-05-17 NL NL6806995A patent/NL6806995A/xx unknown
- 1968-08-16 FR FR163282A patent/FR8160M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1770408B2 (fi) | 1974-04-11 |
AT284843B (de) | 1970-09-25 |
DK129234B (da) | 1974-09-16 |
AT286298B (de) | 1970-12-10 |
GB1180712A (en) | 1970-02-11 |
FR1583872A (fi) | 1969-12-05 |
DE1770408A1 (de) | 1971-10-21 |
FI50333C (fi) | 1976-02-10 |
IL29958A (en) | 1971-04-28 |
DK129234C (fi) | 1975-02-03 |
SE341404B (fi) | 1971-12-27 |
DE1770408C3 (de) | 1974-11-07 |
NL6806995A (fi) | 1968-11-19 |
BE715188A (fi) | 1968-09-30 |
CH498834A (de) | 1970-11-15 |
NO124540B (fi) | 1972-05-02 |
IL29958A0 (en) | 1968-07-25 |
FR8160M (fi) | 1970-08-24 |
FI50333B (fi) | 1975-10-31 |
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