CA2876150A1 - Compostions and methods for cancer immunotherapy - Google Patents
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- CA2876150A1 CA2876150A1 CA2876150A CA2876150A CA2876150A1 CA 2876150 A1 CA2876150 A1 CA 2876150A1 CA 2876150 A CA2876150 A CA 2876150A CA 2876150 A CA2876150 A CA 2876150A CA 2876150 A1 CA2876150 A1 CA 2876150A1
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| RU2015129030A (ru) * | 2012-12-19 | 2017-01-26 | Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем | Фармацевтическое направленное воздействие на путь передачи сигнала циклических динуклеотидов млекопитающих |
| MX374828B (es) | 2013-04-29 | 2025-03-06 | Memorial Sloan Kettering Cancer Center | Composiciones y metodos para alterar la señalizacion del segundo mensajero. |
| US20140329889A1 (en) | 2013-05-03 | 2014-11-06 | The Regents Of The University Of California | Cyclic di-nucleotide induction of type i interferon |
| JP6400082B2 (ja) * | 2013-05-18 | 2018-10-03 | アデュロ バイオテック，インコーポレイテッド | 「インターフェロン遺伝子の刺激因子」依存性シグナル伝達を抑制するための組成物および方法 |
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| US9549944B2 (en) | 2013-05-18 | 2017-01-24 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling |
| JP2016526532A (ja) * | 2013-06-14 | 2016-09-05 | インターベット インターナショナル ベー． フェー． | ＧｐＧオリゴデオキシヌクレオチドおよびサイクリックｄｉ‐ＧＭＰを含む医薬組成物 |
| US10176292B2 (en) | 2013-07-31 | 2019-01-08 | Memorial Sloan-Kettering Cancer Center | STING crystals and modulators |
| PE20211760A1 (es) | 2013-10-18 | 2021-09-07 | Deutsches Krebsforsch | Inhibidores marcados de antigeno prostatico especifico de membrana (psma) que comprenden grupos carboxilicos y una region de enlazador modificada, agentes formadores de imagenes y agentes farmaceuticos que los comprenden |
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| US10441654B2 (en) | 2014-01-24 | 2019-10-15 | Children's Hospital Of Eastern Ontario Research Institute Inc. | SMC combination therapy for the treatment of cancer |
| CN103908468B (zh) * | 2014-04-21 | 2017-02-08 | 上海捌加壹医药科技有限公司 | 环二核苷酸cGAMP在制备抗肿瘤药物中的应用 |
| US10450341B2 (en) | 2014-06-04 | 2019-10-22 | Glaxosmithkline Intellectual Property Development Limited | Cyclic di-nucleotides as modulators of STING |
| CA2958771A1 (en) * | 2014-09-08 | 2016-03-17 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancer |
| US10010607B2 (en) | 2014-09-16 | 2018-07-03 | Institut Curie | Method for preparing viral particles with cyclic dinucleotide and use of said particles for inducing immune response |
| US11236139B2 (en) * | 2014-11-05 | 2022-02-01 | The Regents Of The University Of California | Combination immunotherapy |
| JP6762030B2 (ja) * | 2014-11-20 | 2020-09-30 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 異なる核酸アジュバントの組み合わせによる、新規Ｔｈ１誘導性アジュバントおよびその用途 |
| PL3233882T3 (pl) | 2014-12-16 | 2020-04-30 | Kayla Therapeutics | Fluorowane cykliczne dinukleotydy do indukcji cytokin |
| WO2016096577A1 (en) * | 2014-12-16 | 2016-06-23 | Invivogen | Combined use of a chemotherapeutic agent and a cyclic dinucleotide for cancer treatment |
| GB201501462D0 (en) | 2015-01-29 | 2015-03-18 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| CA3256526A1 (en) | 2015-02-11 | 2025-10-30 | The Johns Hopkins University | Bacteria over-expressing c-di-amp and therapeutic methods |
| KR102873947B1 (ko) * | 2015-05-07 | 2025-10-22 | 베이롤 칼리지 오브 메드신 | 수지상 세포 면역요법 |
| CN108137641B (zh) | 2015-08-13 | 2022-04-01 | 默沙东公司 | 作为sting激动剂的环状双核苷酸化合物 |
| US11453697B1 (en) | 2015-08-13 | 2022-09-27 | Merck Sharp & Dohme Llc | Cyclic di-nucleotide compounds as sting agonists |
| CN106540255A (zh) * | 2015-09-18 | 2017-03-29 | 聊城市奥润生物医药科技有限公司 | 环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用 |
| CN106540254A (zh) * | 2015-09-22 | 2017-03-29 | 聊城市奥润生物医药科技有限公司 | 环二核苷酸cGAMP及其衍生物是潜在免疫佐剂 |
| CN106540253A (zh) * | 2015-09-24 | 2017-03-29 | 聊城市奥润生物医药科技有限公司 | cGAMP及其衍生物在制备抗肿瘤疫苗中的应用 |
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- 2013-06-07 AU AU2013271375A patent/AU2013271375B2/en not_active Ceased
- 2013-06-07 EP EP13799826.6A patent/EP2858722B8/en not_active Not-in-force
- 2013-06-07 IN IN2492MUN2014 patent/IN2014MN02492A/en unknown
- 2013-06-07 SG SG11201407875UA patent/SG11201407875UA/en unknown
- 2013-06-07 US US13/912,960 patent/US9770467B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150010613A1 (en) | 2015-01-08 |
| AU2013271375B2 (en) | 2018-03-22 |
| KR20150022996A (ko) | 2015-03-04 |
| EP2858722A4 (en) | 2015-12-23 |
| WO2013185052A1 (en) | 2013-12-12 |
| NZ702392A (en) | 2017-03-31 |
| EP2858722B8 (en) | 2018-02-21 |
| HK1204302A1 (en) | 2015-11-13 |
| SG10201610251PA (en) | 2017-01-27 |
| IN2014MN02492A (enExample) | 2015-07-17 |
| US9770467B2 (en) | 2017-09-26 |
| CN104507538A (zh) | 2015-04-08 |
| JP6257607B2 (ja) | 2018-01-10 |
| AU2013271375A1 (en) | 2014-12-18 |
| SG11201407875UA (en) | 2014-12-30 |
| EP2858722B1 (en) | 2017-12-13 |
| CN104507538B (zh) | 2018-04-06 |
| JP2015518901A (ja) | 2015-07-06 |
| EP2858722A1 (en) | 2015-04-15 |
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| EEER | Examination request |
Effective date: 20180606 |
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| FZDE | Discontinued |
Effective date: 20200831 |