CA2706637C - Use of alginate oligomers in combating biofilms - Google Patents

Use of alginate oligomers in combating biofilms Download PDF

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Publication number
CA2706637C
CA2706637C CA2706637A CA2706637A CA2706637C CA 2706637 C CA2706637 C CA 2706637C CA 2706637 A CA2706637 A CA 2706637A CA 2706637 A CA2706637 A CA 2706637A CA 2706637 C CA2706637 C CA 2706637C
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Prior art keywords
alginate oligomer
residues
biofilm
alginate
polymerisation
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CA2706637A
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English (en)
French (fr)
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CA2706637A1 (en
Inventor
Edvar Onsoyen
Rolf Myrvold
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Algipharma AS
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Algipharma AS
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
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    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • A61K38/488—Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
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    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21004—Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
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    • C12Y—ENZYMES
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    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21036—Pancreatic elastase (3.4.21.36)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21037—Leukocyte elastase (3.4.21.37), i.e. neutrophil-elastase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Alternative & Traditional Medicine (AREA)
CA2706637A 2007-11-27 2008-10-24 Use of alginate oligomers in combating biofilms Active CA2706637C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99661107P 2007-11-27 2007-11-27
US60/996,611 2007-11-27
PCT/GB2008/003607 WO2009068841A2 (en) 2007-11-27 2008-10-24 Use of alginate oligomers in combating biofilms

Publications (2)

Publication Number Publication Date
CA2706637A1 CA2706637A1 (en) 2009-06-04
CA2706637C true CA2706637C (en) 2016-11-29

Family

ID=40527942

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2706637A Active CA2706637C (en) 2007-11-27 2008-10-24 Use of alginate oligomers in combating biofilms

Country Status (17)

Country Link
US (3) US8680072B2 (enExample)
EP (1) EP2268142B1 (enExample)
JP (2) JP5639475B2 (enExample)
KR (1) KR101690631B1 (enExample)
CN (3) CN104189908B (enExample)
AU (1) AU2008328567B2 (enExample)
BR (1) BRPI0819613B1 (enExample)
CA (1) CA2706637C (enExample)
DK (1) DK2268142T3 (enExample)
ES (1) ES2625866T3 (enExample)
HU (1) HUE034051T2 (enExample)
PL (1) PL2268142T3 (enExample)
PT (1) PT2268142T (enExample)
RS (1) RS55933B1 (enExample)
RU (1) RU2527894C2 (enExample)
SI (1) SI2268142T1 (enExample)
WO (1) WO2009068841A2 (enExample)

Families Citing this family (61)

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BRPI0811530B1 (pt) 2007-05-14 2019-01-02 Research Foundation Of State Univ Of New York composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície
RU2527894C2 (ru) 2007-11-27 2014-09-10 Альгифарма ИПР АС Использование альгинатных олигомеров в борьбе с биопленками
RU2582938C2 (ru) * 2009-06-03 2016-04-27 АльгиФарма АС Альгинатные олигомеры для применения в преодолении множественной лекарственной устойчивости у бактерий
GB0909557D0 (en) * 2009-06-03 2009-07-15 Algipharma Ipr As Anti-microbial alginate oligomers
GB0909529D0 (en) * 2009-06-03 2009-07-15 Algipharma Ipr As Alginate oligomers for the inhibition of microbial adherence to surfaces
GB2477914B (en) 2010-02-12 2012-01-04 Univ Newcastle Compounds and methods for biofilm disruption and prevention
US9572774B2 (en) 2011-05-19 2017-02-21 Savara Inc. Dry powder vancomycin compositions and associated methods
GB201116010D0 (en) * 2011-09-15 2011-10-26 Algipharma As Use of alginate oligomers to enhance the effects of antifungal agents
US10039777B2 (en) 2012-03-20 2018-08-07 Neuro-Lm Sas Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
KR20150013280A (ko) 2012-05-11 2015-02-04 스미스 앤드 네퓨, 인크. 박테리아 균막을 제거하기 위한 세아프로제의 용도
GB201208879D0 (en) * 2012-05-21 2012-07-04 London School Hygiene & Tropical Medicine Therapeutic for treating Clostridium difficile infection
WO2014059313A1 (en) * 2012-10-12 2014-04-17 Lehigh University Thermally stable enzymes, compositions thereof and methods of using same
EP2938415A4 (en) 2012-12-25 2016-05-11 Univ Melbourne MATERIALS AND METHOD
KR101438969B1 (ko) * 2012-12-27 2014-09-11 현대자동차주식회사 무취 에바코어 코팅용 미생물 슈도모나스 나이트로리듀센스 및 이의 용도
US10203329B2 (en) 2013-09-12 2019-02-12 The Johns Hopkins University Biofilm formation to define risk for colon cancer
GB201322777D0 (en) * 2013-12-20 2014-02-05 Algipharma As Use of alginate oligomers as blood anticoagulants
MX2016008304A (es) * 2013-12-23 2017-01-09 Norwegian Univ Of Science And Tech Usos de oligouronatos en el tratamiento de cancer.
JP2017510563A (ja) * 2014-02-28 2017-04-13 アルギファルマ エーエス 嚢胞性線維症及び欠陥ｃｆｔｒイオンチャネル機能に関連する他の病態の治療におけるアルギネートオリゴマーの使用
CN106164236B (zh) * 2014-04-11 2021-02-02 诺维信公司 洗涤剂组合物
FR3024358B1 (fr) * 2014-08-01 2017-11-10 Soc De Courtage Et De Diffusion Codif Int Compositions cosmetiques et complements alimentaires neuro-protecteurs comprenant de l'oligoalginate ayant un degre de polymerisation de 10 pour lutter contre le vieillissement de la peau.
GB201415381D0 (en) * 2014-08-29 2014-10-15 Algipharma As Inhalable powder formulations of alginate oligomers
GB201504878D0 (en) * 2015-03-23 2015-05-06 Algipharma As Use of alginate oligomers and CFTR modulators in the treatment of conditions associated with CFTR dysfuntion
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