CA2573999A1 - Thienopyrimidines useful as aurora kinase inhibitors - Google Patents
Thienopyrimidines useful as aurora kinase inhibitors Download PDFInfo
- Publication number
- CA2573999A1 CA2573999A1 CA002573999A CA2573999A CA2573999A1 CA 2573999 A1 CA2573999 A1 CA 2573999A1 CA 002573999 A CA002573999 A CA 002573999A CA 2573999 A CA2573999 A CA 2573999A CA 2573999 A1 CA2573999 A1 CA 2573999A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- compound
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 230000001404 mediated effect Effects 0.000 claims abstract description 22
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Classifications
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- C07D495/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Landscapes
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- Chemical & Material Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58871804P | 2004-07-16 | 2004-07-16 | |
| US60/588,718 | 2004-07-16 | ||
| US63256804P | 2004-12-01 | 2004-12-01 | |
| US60/632,568 | 2004-12-01 | ||
| PCT/US2005/025340 WO2006036266A1 (en) | 2004-07-16 | 2005-07-15 | Thienopyrimidines useful as aurora kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2573999A1 true CA2573999A1 (en) | 2006-04-06 |
Family
ID=35527256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002573999A Abandoned CA2573999A1 (en) | 2004-07-16 | 2005-07-15 | Thienopyrimidines useful as aurora kinase inhibitors |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7601725B2 (OSRAM) |
| EP (1) | EP1768984B1 (OSRAM) |
| JP (1) | JP2008506714A (OSRAM) |
| KR (1) | KR20070057792A (OSRAM) |
| AT (1) | ATE485300T1 (OSRAM) |
| AU (1) | AU2005290226A1 (OSRAM) |
| BR (1) | BRPI0513405A (OSRAM) |
| CA (1) | CA2573999A1 (OSRAM) |
| DE (1) | DE602005024274D1 (OSRAM) |
| IL (1) | IL180722A0 (OSRAM) |
| MX (1) | MX2007000631A (OSRAM) |
| NZ (1) | NZ552751A (OSRAM) |
| SG (1) | SG156650A1 (OSRAM) |
| WO (1) | WO2006036266A1 (OSRAM) |
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| JP5502072B2 (ja) * | 2008-04-30 | 2014-05-28 | ナショナル ヘルス リサーチ インスティテューツ | オーロラキナーゼ阻害剤としての縮合二環式ピリミジン化合物 |
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| KR101718386B1 (ko) | 2008-09-26 | 2017-03-21 | 내셔날 헬스 리서치 인스티튜트 | 단백질 키나아제 억제제로서의 융합 다환 화합물 |
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- 2005-07-15 WO PCT/US2005/025340 patent/WO2006036266A1/en not_active Ceased
- 2005-07-15 MX MX2007000631A patent/MX2007000631A/es not_active Application Discontinuation
- 2005-07-15 AU AU2005290226A patent/AU2005290226A1/en not_active Abandoned
- 2005-07-15 AT AT05772519T patent/ATE485300T1/de not_active IP Right Cessation
- 2005-07-15 EP EP05772519A patent/EP1768984B1/en not_active Expired - Lifetime
- 2005-07-15 NZ NZ552751A patent/NZ552751A/en not_active IP Right Cessation
- 2005-07-15 KR KR1020077003002A patent/KR20070057792A/ko not_active Ceased
- 2005-07-15 DE DE602005024274T patent/DE602005024274D1/de not_active Expired - Lifetime
- 2005-07-15 CA CA002573999A patent/CA2573999A1/en not_active Abandoned
- 2005-07-15 JP JP2007521708A patent/JP2008506714A/ja active Pending
- 2005-07-15 US US11/182,215 patent/US7601725B2/en not_active Expired - Fee Related
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2007
- 2007-01-16 IL IL180722A patent/IL180722A0/en unknown
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- 2009-10-08 US US12/575,560 patent/US20100179123A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ552751A (en) | 2010-11-26 |
| US20060035908A1 (en) | 2006-02-16 |
| KR20070057792A (ko) | 2007-06-07 |
| AU2005290226A1 (en) | 2006-04-06 |
| ATE485300T1 (de) | 2010-11-15 |
| SG156650A1 (en) | 2009-11-26 |
| JP2008506714A (ja) | 2008-03-06 |
| US7601725B2 (en) | 2009-10-13 |
| IL180722A0 (en) | 2007-06-03 |
| WO2006036266A1 (en) | 2006-04-06 |
| BRPI0513405A (pt) | 2008-05-06 |
| US20100179123A1 (en) | 2010-07-15 |
| MX2007000631A (es) | 2007-03-30 |
| EP1768984B1 (en) | 2010-10-20 |
| EP1768984A1 (en) | 2007-04-04 |
| DE602005024274D1 (de) | 2010-12-02 |
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