AU2003228614A1 - Lxr modulators - Google Patents

Lxr modulators

Info

Publication number
AU2003228614A1
AU2003228614A1 AU2003228614A AU2003228614A AU2003228614A1 AU 2003228614 A1 AU2003228614 A1 AU 2003228614A1 AU 2003228614 A AU2003228614 A AU 2003228614A AU 2003228614 A AU2003228614 A AU 2003228614A AU 2003228614 A1 AU2003228614 A1 AU 2003228614A1
Authority
AU
Australia
Prior art keywords
lxr modulators
lxr
modulators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003228614A
Inventor
Thomas Arrhenius
Jie-Fei Cheng
Yujin Huang
Alex M. Nadzan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AU2003228614A1 publication Critical patent/AU2003228614A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/035—Halogenated hydrocarbons having aliphatic unsaturation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
AU2003228614A 2002-04-23 2003-04-21 Lxr modulators Abandoned AU2003228614A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37464702P 2002-04-23 2002-04-23
US60/374,647 2002-04-23
PCT/US2003/012237 WO2003090869A1 (en) 2002-04-23 2003-04-21 Lxr modulators

Publications (1)

Publication Number Publication Date
AU2003228614A1 true AU2003228614A1 (en) 2003-11-10

Family

ID=29270533

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003228614A Abandoned AU2003228614A1 (en) 2002-04-23 2003-04-21 Lxr modulators

Country Status (2)

Country Link
AU (1) AU2003228614A1 (en)
WO (1) WO2003090869A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2869904B1 (en) 2004-05-07 2006-07-28 Fournier S A Sa Lab MODULATORS OF LXR RECEIVERS
CN1972897A (en) * 2004-06-28 2007-05-30 霍夫曼-拉罗奇有限公司 Novel hexafluoroisopropanol derivatives
JP4936476B2 (en) 2005-06-28 2012-05-23 第一三共株式会社 Test method for LXR ligand
CN103517908A (en) 2010-09-07 2014-01-15 Seoul大学校产学协力财团 Sesterterpene compounds and use thereof
CN102367260A (en) * 2011-12-12 2012-03-07 南京药石药物研发有限公司 Synthesis method of 2-aminopyrimidine-5-boric acid
WO2015106164A1 (en) 2014-01-10 2015-07-16 Rgenix, Inc. Lxr agonists and uses thereof
ES2902661T3 (en) * 2014-07-28 2022-03-29 Sumitomo Chemical Co Amide compound and use thereof for the control of harmful arthropods
TWI664905B (en) * 2014-07-29 2019-07-11 日商住友化學股份有限公司 Noxious arthropod controlling agent containing amide compound
TW202246215A (en) 2015-12-18 2022-12-01 美商亞德利克斯公司 Substituted 4-phenyl pyridine compounds as non-systemic tgr5 agonists
WO2017123568A2 (en) 2016-01-11 2017-07-20 The Rockefeller University Methods for the treatment of myeloid derived suppressor cells related disorders
WO2019104062A1 (en) 2017-11-21 2019-05-31 Rgenix, Inc. Polymorphs and uses thereof
EP4073025B1 (en) 2019-12-13 2024-03-27 Inspirna, Inc. Metal salts and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316503B1 (en) * 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
WO2001003705A1 (en) * 1999-07-08 2001-01-18 Tularik Inc. Compositions and methods for raising hdl cholesterol levels
ES2284817T3 (en) * 2001-01-26 2007-11-16 Chugai Seiyaku Kabushiki Kaisha PROCEDURES FOR THE TREATMENT OF DISEASES WITH INHIBITORS OF MALONIL COA DESCARBOXYLASE.
WO2002064136A2 (en) * 2001-01-26 2002-08-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
KR100637564B1 (en) * 2001-01-26 2006-10-20 추가이 세이야쿠 가부시키가이샤 Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators

Also Published As

Publication number Publication date
WO2003090869A1 (en) 2003-11-06

Similar Documents

Publication Publication Date Title
GB2384570B (en) Modulators
AU2003233704A1 (en) Electro-optic modulators
AU2002335152A1 (en) Robot-phone
AU2000235960A1 (en) Lxr modulators
AU2003228614A1 (en) Lxr modulators
AU2002367810A1 (en) Bis-transition-metal-chelate-probes
AU2002368348A1 (en) Electrosomatogram
AU2002318053A1 (en) Suplier
AU2002348964A1 (en) Snowbike
AU2002341221A1 (en) Honey-brandy
AU2003212130A1 (en) Can
AU2002344387A1 (en) Multifunction-pillow
AU2003214437A1 (en) Integrated mach-zehnder modulator
AU2003201026A1 (en) Modulator arrangement
GB0212926D0 (en) Modulators
GB0212773D0 (en) Modulators
AU2002100739A4 (en) Neuramax
AU2002100498A4 (en) Linline
AU2002100508A4 (en) Photocard
AU2002100026A4 (en) Disc400
AU2002100510A4 (en) Bottlenecker
AU2002100541A4 (en) Backmate
AU2002100160A4 (en) Oxidirator
AU2002100957A4 (en) Sluggit
AU2002100655A4 (en) Armamulch

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase