CA2433021C - Isoindole-imide compounds, compositions, and uses thereof - Google Patents

Isoindole-imide compounds, compositions, and uses thereof Download PDF

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Publication number
CA2433021C
CA2433021C CA2433021A CA2433021A CA2433021C CA 2433021 C CA2433021 C CA 2433021C CA 2433021 A CA2433021 A CA 2433021A CA 2433021 A CA2433021 A CA 2433021A CA 2433021 C CA2433021 C CA 2433021C
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CA
Canada
Prior art keywords
alkyl
dioxo
compound
pharmaceutically acceptable
piperidyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2433021A
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English (en)
French (fr)
Other versions
CA2433021A1 (en
Inventor
Michael J. Robarge
Roger Shen-Chu Chen
George W. Muller
Hon-Wah Man
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Celgene Corp
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Celgene Corp
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Publication of CA2433021A1 publication Critical patent/CA2433021A1/en
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Publication of CA2433021C publication Critical patent/CA2433021C/en
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
CA2433021A 2000-12-27 2001-12-21 Isoindole-imide compounds, compositions, and uses thereof Expired - Fee Related CA2433021C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25837200P 2000-12-27 2000-12-27
US60/258,372 2000-12-27
US09/972,487 US20030045552A1 (en) 2000-12-27 2001-10-05 Isoindole-imide compounds, compositions, and uses thereof
US09/972,487 2001-10-05
PCT/US2001/050401 WO2002059106A1 (en) 2000-12-27 2001-12-21 Isoindole-imide compounds, compositions, and uses thereof

Publications (2)

Publication Number Publication Date
CA2433021A1 CA2433021A1 (en) 2002-08-01
CA2433021C true CA2433021C (en) 2010-02-23

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CA2433021A Expired - Fee Related CA2433021C (en) 2000-12-27 2001-12-21 Isoindole-imide compounds, compositions, and uses thereof

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US (1) US20030045552A1 (US20030045552A1-20030306-C00032.png)
EP (3) EP1363900B1 (US20030045552A1-20030306-C00032.png)
JP (3) JP4284071B2 (US20030045552A1-20030306-C00032.png)
KR (4) KR20070026879A (US20030045552A1-20030306-C00032.png)
AT (1) ATE352548T1 (US20030045552A1-20030306-C00032.png)
AU (3) AU2002248252B2 (US20030045552A1-20030306-C00032.png)
CA (1) CA2433021C (US20030045552A1-20030306-C00032.png)
CY (1) CY1106423T1 (US20030045552A1-20030306-C00032.png)
CZ (1) CZ20032041A3 (US20030045552A1-20030306-C00032.png)
DE (1) DE60126344T2 (US20030045552A1-20030306-C00032.png)
DK (1) DK1363900T3 (US20030045552A1-20030306-C00032.png)
ES (1) ES2275758T3 (US20030045552A1-20030306-C00032.png)
HK (1) HK1061396A1 (US20030045552A1-20030306-C00032.png)
HU (1) HU229003B1 (US20030045552A1-20030306-C00032.png)
IL (2) IL156646A0 (US20030045552A1-20030306-C00032.png)
MX (1) MXPA03005786A (US20030045552A1-20030306-C00032.png)
NZ (1) NZ526893A (US20030045552A1-20030306-C00032.png)
PT (1) PT1363900E (US20030045552A1-20030306-C00032.png)
WO (1) WO2002059106A1 (US20030045552A1-20030306-C00032.png)
ZA (1) ZA200305759B (US20030045552A1-20030306-C00032.png)

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