BR9812682A - Compostos à base de azabenzimidazol para modulação de função de cinase de proteìna de serina/treonina - Google Patents

Compostos à base de azabenzimidazol para modulação de função de cinase de proteìna de serina/treonina

Info

Publication number
BR9812682A
BR9812682A BR9812682-2A BR9812682A BR9812682A BR 9812682 A BR9812682 A BR 9812682A BR 9812682 A BR9812682 A BR 9812682A BR 9812682 A BR9812682 A BR 9812682A
Authority
BR
Brazil
Prior art keywords
azabenzimidazole
protein kinase
serine
threonine protein
compounds
Prior art date
Application number
BR9812682-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Gerald Mcmahon
Bernhard Kutscher
Heinz Weinberger
Harald App
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of BR9812682A publication Critical patent/BR9812682A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR9812682-2A 1997-09-26 1998-09-23 Compostos à base de azabenzimidazol para modulação de função de cinase de proteìna de serina/treonina BR9812682A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6014597P 1997-09-26 1997-09-26
PCT/US1998/019973 WO1999016438A1 (en) 1997-09-26 1998-09-23 Azabenzimidazole-based compounds for modulating serine/threonine protein kinase function

Publications (1)

Publication Number Publication Date
BR9812682A true BR9812682A (pt) 2000-08-22

Family

ID=22027657

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812682-2A BR9812682A (pt) 1997-09-26 1998-09-23 Compostos à base de azabenzimidazol para modulação de função de cinase de proteìna de serina/treonina

Country Status (27)

Country Link
US (2) US6093728A (enExample)
EP (1) EP1017384B1 (enExample)
JP (1) JP2001517699A (enExample)
KR (1) KR100547929B1 (enExample)
CN (1) CN1167420C (enExample)
AR (1) AR017266A1 (enExample)
AT (1) ATE281834T1 (enExample)
AU (1) AU748849B2 (enExample)
BG (1) BG64784B1 (enExample)
BR (1) BR9812682A (enExample)
CA (1) CA2305370C (enExample)
DE (1) DE69827516T2 (enExample)
DK (1) DK1017384T3 (enExample)
ES (1) ES2230719T3 (enExample)
HU (1) HUP0004024A3 (enExample)
IL (4) IL158649A0 (enExample)
NO (1) NO325663B1 (enExample)
NZ (2) NZ503432A (enExample)
PL (1) PL191618B1 (enExample)
PT (1) PT1017384E (enExample)
RU (1) RU2230553C2 (enExample)
SK (1) SK285357B6 (enExample)
TR (1) TR200001546T2 (enExample)
TW (1) TW581815B (enExample)
UA (1) UA72448C2 (enExample)
WO (1) WO1999016438A1 (enExample)
ZA (1) ZA988797B (enExample)

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CN103998036B (zh) 2011-10-19 2017-05-31 西格诺药品有限公司 利用tor激酶抑制剂治疗癌症
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CN104271159B (zh) 2012-02-24 2017-11-28 西格诺药品有限公司 利用tor激酶抑制剂联合治疗来治疗非小细胞肺癌的方法
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Also Published As

Publication number Publication date
CN1278172A (zh) 2000-12-27
US6855723B2 (en) 2005-02-15
CA2305370C (en) 2006-11-28
PL191618B1 (pl) 2006-06-30
ATE281834T1 (de) 2004-11-15
BG64784B1 (bg) 2006-04-28
AU748849B2 (en) 2002-06-13
SK285357B6 (sk) 2006-11-03
TR200001546T2 (tr) 2000-10-23
PL339744A1 (en) 2001-01-02
NZ517808A (en) 2003-07-25
JP2001517699A (ja) 2001-10-09
PT1017384E (pt) 2005-03-31
ZA988797B (en) 1999-12-02
NO325663B1 (no) 2008-07-07
AR017266A1 (es) 2001-09-05
IL135109A (en) 2007-07-04
NO20001555L (no) 2000-03-24
CA2305370A1 (en) 1999-04-08
KR100547929B1 (ko) 2006-02-02
KR20010015623A (ko) 2001-02-26
EP1017384B1 (en) 2004-11-10
IL158649A (en) 2006-12-10
UA72448C2 (en) 2005-03-15
HUP0004024A3 (en) 2001-10-29
TW581815B (en) 2004-04-01
US20030181480A1 (en) 2003-09-25
BG104356A (en) 2000-12-29
US6093728A (en) 2000-07-25
EP1017384A1 (en) 2000-07-12
HK1032206A1 (en) 2001-07-13
NO20001555D0 (no) 2000-03-24
HUP0004024A2 (hu) 2001-04-28
RU2230553C2 (ru) 2004-06-20
DK1017384T3 (da) 2005-01-31
IL158649A0 (en) 2004-05-12
DE69827516D1 (de) 2004-12-16
ES2230719T3 (es) 2005-05-01
AU9578198A (en) 1999-04-23
WO1999016438A1 (en) 1999-04-08
NZ503432A (en) 2002-11-26
IL135109A0 (en) 2001-05-20
CN1167420C (zh) 2004-09-22
DE69827516T2 (de) 2005-12-01
SK4152000A3 (en) 2002-02-05

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