BR112012031161A2 - composições de enxerto não incrustante, antimicrobiano, antitrombogênico - Google Patents

composições de enxerto não incrustante, antimicrobiano, antitrombogênico

Info

Publication number
BR112012031161A2
BR112012031161A2 BR112012031161A BR112012031161A BR112012031161A2 BR 112012031161 A2 BR112012031161 A2 BR 112012031161A2 BR 112012031161 A BR112012031161 A BR 112012031161A BR 112012031161 A BR112012031161 A BR 112012031161A BR 112012031161 A2 BR112012031161 A2 BR 112012031161A2
Authority
BR
Brazil
Prior art keywords
fibrinogen
antithrombogenic
antimicrobial
antifouling
graft compositions
Prior art date
Application number
BR112012031161A
Other languages
English (en)
Portuguese (pt)
Inventor
Arthur J Coury
Chad Huval
Christopher R Loose
Jun Li
Michael Bouchard
Zheng Zhang
Original Assignee
Semprus Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Semprus Biosciences Corp filed Critical Semprus Biosciences Corp
Publication of BR112012031161A2 publication Critical patent/BR112012031161A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0088—Chemical modification of the substrate by grafting of a monomer onto the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F255/00—Macromolecular compounds obtained by polymerising monomers on to polymers of hydrocarbons as defined in group C08F10/00
    • C08F255/02—Macromolecular compounds obtained by polymerising monomers on to polymers of hydrocarbons as defined in group C08F10/00 on to polymers of olefins having two or three carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/83—Chemically modified polymers
    • C08G18/836—Chemically modified polymers by phosphorus containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
    • C08G64/42—Chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/38—Polysiloxanes modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/16—Chemical modification with polymerisable compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/16—Chemical modification with polymerisable compounds
    • C08J7/18—Chemical modification with polymerisable compounds using wave energy or particle radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/10—Homopolymers or copolymers of propene
    • C08J2323/12—Polypropene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2369/00—Characterised by the use of polycarbonates; Derivatives of polycarbonates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2383/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers
    • C08J2383/04—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2433/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2433/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
    • C08J2433/14—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24355—Continuous and nonuniform or irregular surface on layer or component [e.g., roofing, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/26—Web or sheet containing structurally defined element or component, the element or component having a specified physical dimension
    • Y10T428/263—Coating layer not in excess of 5 mils thick or equivalent
    • Y10T428/264—Up to 3 mils
    • Y10T428/265—1 mil or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/30—Woven fabric [i.e., woven strand or strip material]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/60—Nonwoven fabric [i.e., nonwoven strand or fiber material]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Laminated Bodies (AREA)
  • Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
BR112012031161A 2010-06-09 2011-06-09 composições de enxerto não incrustante, antimicrobiano, antitrombogênico BR112012031161A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35305910P 2010-06-09 2010-06-09
PCT/US2011/039790 WO2011156589A2 (en) 2010-06-09 2011-06-09 Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions

Publications (1)

Publication Number Publication Date
BR112012031161A2 true BR112012031161A2 (pt) 2016-11-01

Family

ID=45096431

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012031161A BR112012031161A2 (pt) 2010-06-09 2011-06-09 composições de enxerto não incrustante, antimicrobiano, antitrombogênico

Country Status (12)

Country Link
US (2) US9096703B2 (https=)
EP (1) EP2579908A4 (https=)
JP (1) JP6083071B2 (https=)
KR (1) KR20130110143A (https=)
CN (1) CN103037913B (https=)
AU (1) AU2011264834B2 (https=)
BR (1) BR112012031161A2 (https=)
CA (1) CA2799636A1 (https=)
NZ (1) NZ603705A (https=)
SG (1) SG186180A1 (https=)
WO (1) WO2011156589A2 (https=)
ZA (1) ZA201208950B (https=)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5548121B2 (ja) 2007-05-14 2014-07-16 リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク バイオフィルム中の細菌細胞における生理学的分散応答の誘導
US8445717B2 (en) 2008-11-20 2013-05-21 Chd Bioscience, Inc. α-Keto alkylperacids and methods for producing and using the same
PT2358669E (pt) 2008-11-20 2014-08-29 Chd Bioscience Inc Alfa-ceto-perácidos e métodos para produzir e usar os mesmos
EP2408482A1 (en) 2009-03-19 2012-01-25 Millipore Corporation Removal of microorganisms from fluid samples using nanofiber filtration media
US20110099777A1 (en) * 2009-11-04 2011-05-05 Corry Charles D Earring Clasp Having Flexible Member
US11284621B2 (en) 2010-04-15 2022-03-29 Armis Biopharma, Inc. Compositions comprising peroxyacid and methods for producing and using the same
CA2799786A1 (en) 2010-06-09 2011-12-15 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft compositions
SG185659A1 (en) 2010-08-10 2012-12-28 Emd Millipore Corp Method for retrovirus removal
US9044527B2 (en) 2011-02-17 2015-06-02 Chd Bioscience, Inc. Wound care products with peracid compositions
CN105413480B (zh) 2011-04-01 2019-03-29 Emd密理博公司 含有纳米纤维的复合材料结构
EP2726870B1 (en) 2011-06-29 2018-10-03 Academia Sinica The capture, purification and release of biological substance using a surface coating
WO2013035206A1 (ja) * 2011-09-09 2013-03-14 ヘンケル・アクチェンゲゼルシャフト・ウント・コムパニー・コマンディットゲゼルシャフト・アウフ・アクチェン 電子装置用シール剤組成物
MX2014007208A (es) 2011-12-14 2015-04-14 Semprus Biosciences Corp Modificacion en la superficie para cateteres de dialisis.
US9000063B2 (en) 2011-12-14 2015-04-07 Semprus Biosciences Corporation Multistep UV process to create surface modified contact lenses
US9120119B2 (en) 2011-12-14 2015-09-01 Semprus Biosciences Corporation Redox processes for contact lens modification
WO2013090693A1 (en) * 2011-12-14 2013-06-20 Semprus Biosciences Corp. Luminal modifications for catheters
WO2013090790A1 (en) 2011-12-14 2013-06-20 Semprus Biosciences Corp. Silicone hydrogel contact lens modified using lanthanide or transition metal oxidants
CA2859195C (en) 2011-12-14 2016-09-27 Semprus Biosciences Corp. Imbibing process for contact lens surface modification
CA2858730C (en) 2011-12-14 2017-07-18 Semprus Biosciences Corp. Surface modified contact lenses
EP2684942A1 (en) * 2012-07-10 2014-01-15 The Swatch Group Research and Development Ltd. Agent for the surface epilamization of an article
BR112015003403A2 (pt) * 2012-08-14 2017-07-04 Chd Bioscience Inc produtos de cuidado de ferida com composições de perácido
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
BR112015008847A2 (pt) 2012-10-18 2017-07-04 Chd Bioscience Inc composições compreendendo ácido peróxido
US11850331B2 (en) * 2013-03-11 2023-12-26 Teleflex Medical Incorporated Devices with anti-thrombogenic and anti-microbial treatment
US9737250B2 (en) 2013-03-15 2017-08-22 Dexcom, Inc. Membrane for continuous analyte sensors
CN104073114B (zh) * 2013-03-29 2016-04-13 中国科学院兰州化学物理研究所 一种具有防海洋生物污染功能表面材料的制备方法
CA2908202A1 (en) * 2013-04-01 2014-10-09 Cytosorbents Corporation Hemocompatibility modifiers for cross-linked polymeric material
GB201306980D0 (en) * 2013-04-17 2013-05-29 Blueberry Therapeutics Ltd Methods
JP6454325B2 (ja) * 2013-04-26 2019-01-16 バイオインタラクションズ・リミテッドＢｉｏＩｎｔｅｒａｃｔｉｏｎｓ Ｌｔｄ 生物活性被覆
USRE49528E1 (en) 2013-04-26 2023-05-16 Biointeractions Ltd. Bioactive coatings
US10597540B2 (en) * 2013-05-27 2020-03-24 Jsr Corporation Surface treatment agent for surface configured from inorganic material, tool and device having modified surface, and method for manufacturing tool and device
WO2014194268A1 (en) * 2013-05-30 2014-12-04 The University Of Akron Switchable antimicrobial and antifouling carboxybetaine-based hydrogels
CN103271897A (zh) * 2013-06-04 2013-09-04 李春启 美司那在制备抗血管生成类药物中的应用
US10183099B2 (en) 2013-10-07 2019-01-22 International Business Machines Corporation Antimicrobial and antifouling catechol-containing polycarbonates for medical applications
US20160251470A1 (en) * 2013-10-14 2016-09-01 The University Of Akron Zwitterionic polysaccharide polymers having antifouling, antimicrobial and optical transparency properties
US10150088B2 (en) 2013-11-08 2018-12-11 Tufts University Zwitterion-containing membranes
US9578879B1 (en) 2014-02-07 2017-02-28 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
EP3111969B1 (en) * 2014-02-24 2019-09-11 Terumo Kabushiki Kaisha Medical material and medical instrument using medical material
TW201623605A (zh) 2014-04-01 2016-07-01 中央研究院 用於癌症診斷及預後之方法及系統
CN103966851B (zh) * 2014-05-22 2016-08-24 安徽工程大学 一种功能性aopan纳米纤维及其制备方法
KR20190011838A (ko) 2014-06-26 2019-02-07 이엠디 밀리포어 코포레이션 개선된 먼지 포집 능력을 갖는 필터 구조
JP6662772B2 (ja) * 2014-07-03 2020-03-11 富士フイルム和光純薬株式会社 グラフトポリマー、樹脂着色物、その製造方法およびその樹脂着色物を含む樹脂組成物
US9782727B2 (en) 2014-07-14 2017-10-10 International Business Machines Corporation Filtration membranes with functionalized star polymers
US10112198B2 (en) 2014-08-26 2018-10-30 Academia Sinica Collector architecture layout design
US10851241B2 (en) 2014-11-19 2020-12-01 Cytiva Sweden Ab Zwitterion-functionalized multicomponent copolymers and associated polymer blends and membranes
US9931598B2 (en) 2015-02-16 2018-04-03 International Business Machines Corporation Anti-fouling coatings with star polymers for filtration membranes
US10005042B2 (en) 2015-02-16 2018-06-26 International Business Machines Corporation Thin film composite forward osmosis membranes with performance enhancing layers
WO2016144926A1 (en) * 2015-03-10 2016-09-15 Tufts University Two-layer nanofiltration membranes
KR102206959B1 (ko) 2015-04-17 2021-01-25 이엠디 밀리포어 코포레이션 접선방향 유동 여과 모드에서 작동되는 나노섬유 한외여과막을 사용하여 샘플에서 목적하는 생물학적 물질을 정제하는 방법
US10351524B2 (en) * 2015-07-01 2019-07-16 National Chung Cheng University Hydrocarbyl carboxybetaine and method for preventing hofmann elimination in alkaline environment
JP2018520838A (ja) * 2015-07-24 2018-08-02 テレフレックス メディカル インコーポレイテッド 抗菌コーティングを有する埋め込み型整形外科用装置
CA3002099A1 (en) 2015-12-30 2017-07-06 Dexcom, Inc. Diffusion resistance layer for analyte sensors
SG11201804608PA (en) 2016-01-20 2018-06-28 Akzo Nobel Coatings Int Bv Coating composition for substrates immersed in water
US10107726B2 (en) 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
JP6362224B2 (ja) * 2016-05-09 2018-07-25 住友ゴム工業株式会社 表面改質方法
JP6731500B2 (ja) * 2016-05-20 2020-07-29 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド Ｒａｆｔ重合による新規付着防止技術
CN106119820B (zh) 2016-06-01 2018-06-22 华南理工大学 一种利用可控接枝技术提高材料表面血液相容性的方法
CA3027200A1 (en) 2016-06-13 2017-12-21 Massachusetts Institute Of Technology Biocompatible zwitterionic polymer coatings and hydrogels for reducing foreign body response and fibrosis
CN109562202B (zh) * 2016-06-24 2022-09-27 艾奥瓦大学研究基金会 持久的可光聚合的交联防污涂层
US20190185629A1 (en) * 2016-08-05 2019-06-20 Microoptx Inc. Polymeric devices and methods of making
EP3296010B1 (en) * 2016-09-14 2023-04-26 Gambro Lundia AB Acrylonitrile-based membrane with low thrombogenicity
KR20180082706A (ko) 2017-01-10 2018-07-19 한국교통대학교산학협력단 Uv오존을 이용하여 고분자 표면에 금속나노입자를 형성시키는 방법, 그 방법에 의해 제조된 고분자 필름 및 항균 필름
WO2018187693A1 (en) 2017-04-06 2018-10-11 TearDX LLC Ocular devices and methods for the employment thereof
LU100270B1 (en) * 2017-05-05 2018-12-03 Luxembourg Inst Science & Tech List Inkjet printing process
EP4732889A2 (en) 2017-06-07 2026-04-29 Supira Medical, Inc. Intravascular fluid movement devices, systems, and methods of use
KR102029246B1 (ko) 2017-07-10 2019-10-07 울산과학기술원 조명 겸용 촬영 장치
EP3655142B1 (en) 2017-07-21 2026-02-25 Merck Millipore Ltd Non-woven fiber membranes
CN107376094A (zh) * 2017-07-31 2017-11-24 深圳市天可医疗科技有限公司 一种导管鞘的制造方法
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
CN108203510B (zh) * 2018-01-12 2020-02-14 哈尔滨工业大学（威海） 一种用于超微滤膜改性的甜菜碱型聚酰亚胺添加剂的制备方法
JP7410034B2 (ja) 2018-02-01 2024-01-09 シファメド・ホールディングス・エルエルシー 血管内血液ポンプならびに使用および製造の方法
CN108498868B (zh) * 2018-04-03 2020-09-15 北京大学口腔医学院 具有细胞外基质电学拓扑特征的带电复合膜及其制备方法
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
CN108905293B (zh) * 2018-06-15 2020-07-10 山东交通学院 一种具有防污和染料吸附功能的仿生油水分离材料及其制备方法
WO2020028537A1 (en) 2018-07-31 2020-02-06 Shifamed Holdings, Llc Intravascaular blood pumps and methods of use
WO2020073047A1 (en) 2018-10-05 2020-04-09 Shifamed Holdings, Llc Intravascular blood pumps and methods of use
CN109289087B (zh) * 2018-10-09 2021-02-12 温州医科大学附属第一医院 一种用于治疗激素性股骨头坏死的复合支架及其制备方法
LU100971B1 (en) * 2018-10-25 2020-04-27 Luxembourg Inst Science & Tech List Inkjet printing process
EP3887875B1 (en) * 2018-11-30 2025-08-13 Alcon Inc. Environmental scanning electron microscopy analysis for contact lens coating selection and manufacturing
WO2020123503A1 (en) * 2018-12-10 2020-06-18 Giridhar Thiagarajan Antimicrobial implantable medical devices
US20220127421A1 (en) * 2019-03-05 2022-04-28 University Of Florida Research Foundation, Inc. Polyurethane copolymers and blends, methods of manufacture thereof and articles containing the same
EP3937995B1 (en) 2019-03-14 2024-08-07 University of Washington Methods comprising zwitterionic copolymer coatings
EP3962626A1 (en) 2019-05-01 2022-03-09 Ascend Performance Materials Operations LLC Filter media comprising polyamide nanofiber layer
KR102259292B1 (ko) * 2019-05-10 2021-06-03 서울대학교 산학협력단 열을 이용한 보형물의 코팅방법
WO2020250676A1 (ja) 2019-06-13 2020-12-17 富士フイルム株式会社 内視鏡用コーティング組成物、内視鏡用潤滑性部材、内視鏡用潤滑性部材の製造方法、内視鏡用可撓管、及び内視鏡
WO2021011473A1 (en) 2019-07-12 2021-01-21 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
EP4010046A4 (en) 2019-08-07 2023-08-30 Calomeni, Michael Catheter blood pumps and collapsible pump housings
EP4034221B1 (en) 2019-09-25 2024-11-13 Shifamed Holdings, LLC Catheter blood pumps and collapsible pump housings
WO2021062260A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible blood conduits
EP4034192B1 (en) 2019-09-25 2025-12-24 Supira Medical, Inc. Intravascular blood pump systems and methods of use and control thereof
EP4072650A4 (en) 2019-12-11 2024-01-10 Shifamed Holdings, LLC Descending aorta and vena cava blood pumps
US12599758B2 (en) 2019-12-19 2026-04-14 Shifamed Holdings, Llc Intravascular blood pumps, motors, and fluid control
CN111184914B (zh) * 2020-02-17 2021-10-15 四川大学 一种功能化脱细胞基质生物材料及其制备方法和应用
CN111330090B (zh) * 2020-03-02 2022-04-05 中国科学院宁波材料技术与工程研究所 一种血液透析器的表面抗凝修饰方法及其应用
CN116234508A (zh) 2020-06-05 2023-06-06 伊纳里医疗有限公司 可再捕获的漏斗导管以及相关联的系统和方法
CN111909342B (zh) * 2020-06-30 2023-05-23 合肥科天水性科技有限责任公司 一种抗菌水性聚氨酯树脂及其制备方法
CN111840661B (zh) * 2020-07-30 2021-08-10 齐鲁工业大学 一种高电位超亲水性多肽单层膜及其制备方法与应用
CN116390691A (zh) * 2020-08-10 2023-07-04 歌尔4梅德股份有限公司 自组装的两亲性肽水凝胶
CN112691872A (zh) * 2020-12-14 2021-04-23 北京航空航天大学 一种水下超疏油聚合物刷涂层及其制备方法
CN112745508B (zh) * 2020-12-29 2022-11-18 中国科学院理化技术研究所 一种亲水、抗菌和抗蛋白粘附的硅橡胶及其制备方法
CN112961277A (zh) * 2021-02-05 2021-06-15 浙江本立科技股份有限公司 一种高选择性碳酸司维拉姆的制备方法
JP2022131579A (ja) 2021-02-26 2022-09-07 キオクシア株式会社 分析装置および分析方法
CN115007119A (zh) * 2021-03-03 2022-09-06 中国科学院大连化学物理研究所 一种含有两性离子的亲水微球及其制备和应用
CN113019409B (zh) * 2021-03-23 2022-07-29 四川轻化工大学 一种Bi2O2CO3/BiOCl催化剂的制备方法及其应用
KR102573617B1 (ko) * 2021-03-24 2023-09-01 주식회사 아이엠씨 항균 필름 및 이의 제조방법
CN113325049B (zh) * 2021-04-29 2022-08-30 苏州中星医疗技术有限公司 一种微溶胀型生物相容性膜及其制备方法
CN113667141B (zh) * 2021-07-09 2023-10-03 深圳华源再生医学有限公司 抗蛋白粘附的海藻酸盐水凝胶及其制备方法和应用
US12247090B2 (en) * 2021-07-13 2025-03-11 Duke University Enzyme-mediated free radical initiating systems for the production of hydrogels and controlled radical polymerization processes
CN113577401B (zh) * 2021-07-15 2022-06-07 南通纺织丝绸产业技术研究院 一种长效抗菌抗狭窄功能尿道支架及其制备方法
KR102707676B1 (ko) * 2021-10-28 2024-09-19 주식회사 티엠에스헬스케어 우수한 물성과 생체 안정성, 박테리아 부착 및 생물막 형성 감소, sod 활성 증폭효능을 가지는 치아 교정용 및 치과 질환 예방 및 치료용 조성물
TWI789109B (zh) * 2021-11-10 2023-01-01 南臺學校財團法人南臺科技大學 抗生物沾黏共聚物及其製備方法
CN114213632B (zh) * 2021-12-14 2023-08-22 济南大学 一种具有抗蛋白吸附的两亲性含氟共聚物膜的制备方法及应用
CN114366858B (zh) * 2021-12-31 2023-07-25 东华大学 一种具有抗菌防痰栓功能的气管导管及其制备方法
KR102506889B1 (ko) * 2022-04-25 2023-03-06 성진용 인테리어용 조립식 건축자재
CN114984299B (zh) * 2022-05-30 2023-01-06 浙江大学 一种用于治疗糖尿病创面的抗菌抗氧化水凝胶敷料及其制备方法
CN115075012B (zh) * 2022-06-16 2023-07-07 太原理工大学 一种防污网具及其制备方法和应用
CN115317515B (zh) * 2022-07-19 2024-08-20 沈阳药科大学 氯尼达明/牛血清白蛋白/磷酸铁多效协同仿生矿化纳米制剂及制备方法和应用
US20260043800A1 (en) * 2022-08-15 2026-02-12 Solventum Intellectual Properties Company Functionalized porous substrates and their use for detecting analytes
CN115382025B (zh) 2022-09-06 2024-06-25 泰州度博迈医疗器械有限公司 一种在医用植入材料表面构建亲水防污涂层的方法
CN115845132B (zh) * 2022-10-09 2024-02-13 北京博辉瑞进生物科技有限公司 生物补片及其制备方法和用途
CN116328047B (zh) * 2022-12-22 2023-10-10 上海琦识医疗科技有限公司 一种精密医用导管
CN116282580B (zh) * 2023-03-30 2024-09-17 中国科学技术大学 一种利用微生物代谢产物降解微污染物的方法
CN116574394B (zh) * 2023-04-19 2024-11-19 南京溯远基因科技有限公司 一种敏感性荧光染料剂及其制备方法
CN116750844B (zh) * 2023-07-21 2023-12-05 青岛深海星空投资控股有限公司 一种电场加膜法松散耦合化净水设备
WO2025064843A1 (en) * 2023-09-20 2025-03-27 The Regents Of The University Of Colorado, A Body Corporate Stabilization of enzymes on mixed polymer brush with aromatic groups
WO2025147390A1 (en) * 2024-01-04 2025-07-10 Edwards Lifesciences Corporation Entangled hydrogel network

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4636208A (en) 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
US4877864A (en) 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US5013649A (en) 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
US6432919B1 (en) 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
US5688678A (en) 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US5739236A (en) 1991-04-24 1998-04-14 Biocompatibles Limited Biocompatible zwitterion polymers
US5180375A (en) 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
EP0592562B1 (en) 1991-06-25 1999-01-07 Genetics Institute, Inc. Bmp-9 compositions
GB9118597D0 (en) * 1991-08-30 1991-10-16 Biocompatibles Ltd Polymer treatments
GB9226791D0 (en) 1992-12-23 1993-02-17 Biocompatibles Ltd New materials
US5800373A (en) 1995-03-23 1998-09-01 Focal, Inc. Initiator priming for improved adherence of gels to substrates
JP3341503B2 (ja) 1994-11-09 2002-11-05 東レ株式会社 抗血栓性医療材料およびそれを用いたカテーテル
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5811151A (en) 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
GB9624130D0 (en) 1996-11-20 1997-01-08 Biocompatibles Ltd Biocompatible compositions
JPH1147263A (ja) 1997-07-29 1999-02-23 Sumitomo Bakelite Co Ltd 抗血液凝固表面処理材料
US5997895A (en) 1997-09-16 1999-12-07 Integra Lifesciences Corporation Dural/meningeal repair product using collagen matrix
US6054504A (en) 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
DE69920198T2 (de) 1998-04-13 2005-09-22 Massachusetts Institute Of Technology, Cambridge Kamm-polymere zur regelung der zelloberflächenwechselwirkung
JPH11313675A (ja) 1998-04-30 1999-11-16 Hoechst Marion Roussel Kk ヒトｂｍｐ−７プロモーターおよびこれを用いた骨関連物質の探索法
WO2000063079A1 (en) 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
DE10022371A1 (de) 1999-05-20 2000-11-23 Bayer Ag Pfropfcopolymere enthaltende Feststoffpräparationen
EP1189553B1 (en) 1999-06-24 2004-03-31 Abbott Vascular Devices Limited Balloon expandable stent
US6358557B1 (en) 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces
AU770404B2 (en) 1999-09-22 2004-02-19 Surmodics, Inc. Water-soluble coating agents bearing initiator groups and coating process
US6533415B2 (en) 2000-03-21 2003-03-18 Menicon Co., Ltd. Ocular lens material having hydrophilic surface and process for preparing the same
US6589665B2 (en) 2000-05-30 2003-07-08 Novartis Ag Coated articles
JP2004513981A (ja) 2000-07-17 2004-05-13 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 生物種の吸着に耐える表面
US6852353B2 (en) 2000-08-24 2005-02-08 Novartis Ag Process for surface modifying substrates and modified substrates resulting therefrom
US6558734B2 (en) 2001-02-09 2003-05-06 Medtronic, Inc. Methods for modifying surfaces of articles
US6844028B2 (en) 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
DE10130968B4 (de) 2001-06-27 2009-08-20 Envisiontec Gmbh Beschichtetes Polymermaterial, dessen Verwendung sowie Verfahren zu dessen Herstellung
DE10163681A1 (de) 2001-12-21 2003-07-10 Roehm Gmbh Verfahren zur Herstellung von Beschichtungen
US6559242B1 (en) 2002-05-02 2003-05-06 Ford Global Technologies, Inc. Surface activation and coating processes of a thermoplastic olefin using an aqueous immersion bath and products produced thereby
US7431888B2 (en) 2002-09-20 2008-10-07 The Regents Of The University Of California Photoinitiated grafting of porous polymer monoliths and thermoplastic polymers for microfluidic devices
JP2004121618A (ja) 2002-10-04 2004-04-22 Toray Ind Inc 医療用管状物の内面コート方法
EP1558658B1 (fr) 2002-11-07 2012-12-19 Rhodia Chimie Copolymere a structure controlee presentant une partie amphotere ou zwitterionique.
US7220491B2 (en) 2002-12-19 2007-05-22 Kimberly-Clark Worldwide, Inc. Lubricious coating for medical devices
US7632389B2 (en) 2003-04-09 2009-12-15 Merck Patent Gmbh Open tube suitable for separation purposes comprising covalently bonded zwitterionic betaine groups
US7238426B2 (en) 2003-08-13 2007-07-03 Sequant Ab Column packing material
US20060057180A1 (en) * 2004-02-20 2006-03-16 Ashutosh Chilkoti Tunable nonfouling surface of oligoethylene glycol
US20070111258A1 (en) 2005-06-22 2007-05-17 Kaufman Randal J Compositions and methods for modulating the acute phase response
US20070048249A1 (en) 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
CA2619361C (en) * 2005-08-25 2015-10-20 University Of Washington Super-low fouling sulfobetaine and carboxybetaine materials and related methods
US20070122550A1 (en) 2005-11-30 2007-05-31 Narayanan Pallassana V Amphiphilic polymeric coating
FR2894585B1 (fr) 2005-12-14 2012-04-27 Rhodia Recherches Et Tech Copolymere comprenant des unites zwitterioniques et d'autres unites, composition comprenant le copolymere, et utilisation
US20070254006A1 (en) 2006-02-15 2007-11-01 Massachusetts Institute Of Technology Medical Devices and Coatings with Non-Leaching Antimicrobial Peptides
WO2008006911A1 (en) 2006-07-14 2008-01-17 Biocompatibles Uk Limited Coated implant
EP2069412B1 (en) 2006-08-07 2019-01-02 University of Washington Mixed charge copolymers and hydrogels
EP1892080A1 (en) 2006-08-25 2008-02-27 Sauflon CL Limited Method of coating a contact lens
MX2009007101A (es) * 2006-12-29 2009-12-01 Univ Washington Superficies y materiales antibioincrustación bifuncionales.
CN100496683C (zh) * 2007-04-28 2009-06-10 浙江大学 两亲性含氟共聚物对聚四氟乙烯多孔膜的表面改性方法
US20090155335A1 (en) * 2007-12-05 2009-06-18 Semprus Biosciences Corp. Non-leaching non-fouling antimicrobial coatings
US8062751B2 (en) * 2007-12-21 2011-11-22 Chung Yuan Christian University Low biofouling filtration membranes and their forming method
WO2010065960A2 (en) * 2008-12-05 2010-06-10 Semprus Biosciences Corp. Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
US8414980B2 (en) * 2009-08-21 2013-04-09 Atomic Energy Council-Institute Of Nuclear Energy Research Method for hydrophobic and oleophobic modification of polymeric materials with atmospheric plasmas

Also Published As

Publication number Publication date
JP2013528114A (ja) 2013-07-08
NZ603705A (en) 2014-10-31
WO2011156589A4 (en) 2012-06-28
US10117974B2 (en) 2018-11-06
JP6083071B2 (ja) 2017-02-22
EP2579908A4 (en) 2016-03-23
WO2011156589A2 (en) 2011-12-15
CN103037913B (zh) 2016-03-09
EP2579908A2 (en) 2013-04-17
CA2799636A1 (en) 2011-12-15
SG186180A1 (en) 2013-01-30
US20110305872A1 (en) 2011-12-15
US20150045515A1 (en) 2015-02-12
AU2011264834A1 (en) 2012-12-06
KR20130110143A (ko) 2013-10-08
CN103037913A (zh) 2013-04-10
AU2011264834B2 (en) 2015-03-12
ZA201208950B (en) 2014-04-30
US9096703B2 (en) 2015-08-04
WO2011156589A3 (en) 2012-04-26

Similar Documents

Publication Publication Date Title
BR112012031161A2 (pt) composições de enxerto não incrustante, antimicrobiano, antitrombogênico
PL404239A1 (pl) Zmodyfikowane srodki wypelniajace i zawierajace je elastomerowe kompozyty
WO2011156590A3 (en) Non-fouling, anti-microbial, anti-thrombogenic graft compositions
MX2012007209A (es) Agentes de recubrimiento y articulos recubiertos.
BRPI0823506A8 (pt) composições e métodos para a produção de isoprene
PL2220145T3 (pl) Kompozycja polimerowa, sposób wytwarzania kompozycji polimerowej, wyroby na bazie tej kompozycji polimerowej i zastosowanie tych wyrobów
WO2007117838A3 (en) Atomic layer deposition coatings for implantable medical devices
BR112012020857A2 (pt) substrato gerador de aerossol para artigos para fumar
MX2009006033A (es) Composiciones y articulos que contienen una matriz de polimero reticulado y un liquido activo inmovilizado, asi como metodos para fabricarlos.
BR112013021231A2 (pt) revestimentos super-hidrofóbicos e oleofóbicos com sistemas ligantes de baixo voc
AR059856A1 (es) Dispersiones acuosas de particulas encerradas en un polimero, las composiciones para recubrimiento y sustratos recubiertos relacionados
WO2008005509A3 (en) Methods and compositions for altering biological surfaces
WO2008053444A3 (en) Treating a respiratory condition with bifidobacterium
WO2010144444A3 (en) Articles containing silicone compositions and methods of making such articles
DE502007006105D1 (de) Flammgeschützte schlagzähmodifizierte polycarbonat-zusammensetzungen
ATE502658T1 (de) Polymer-komposit-stent mit polymerteilchen
BR112014024011A8 (pt) Processos cosméticos para pele e folha cosmética para pele
MY173526A (en) Novel anti-?5?1 antibodies and uses thereof
BRPI0820271A2 (pt) Métodos de aumentar a sobrevivência de uma proteína de coagulação pela inibição da interação com um receptor de depuração, de aumentar a sobrevivência de fator viii que inibe receptores de depruração de proteína de coagulação, de tratar um indivíduo com uma doença de coagulação sanguínea, e de tratar uma doença que tem por característica uma deficiência de fator viii em um indivíduo, e, proteína de ...métodos de aumentar a sobrevivência de uma proteína de coagulação pela inibição da interação com um receptor de depuração, de aumentar a sobrevivência de fator viii pela inibição da interação com um receptor de depuração, de preparar uma composição que inibe receptores de depuração de proteína de coagulação, de tratar um indivíduo com uma doença de coagulação sanguínea, e de tratar uma doença que tem por característica uma deficiência de fator viii em um indivíduo, e, proteína de coagulação modificada.
EP2315747A4 (en) METHOD AND COMPOSITIONS RELATED TO SYNTHETIC BETA-1,6 GLUCOSAMINE OLIGOSACCHARIDES
WO2008085221A3 (en) Therapeutic use of cd31 expressing cells
EP2832342A3 (en) Dental compositions with calcium phosphorus releasing glass
BRPI1006713A2 (pt) artigos retrorrefletivos
TR201906595T4 (tr) Ağ-şekilli veya ada-şekilli kristal oranı düşük hidroksiapatit ile kaplanmış implant ve bunu kaplamak için yöntem.
BR112013021661A2 (pt) objetivação de fator de coagulação a tlt-1 sobre plaquetas ativadas

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]