US8038994B2
(en)
|
1996-05-15 |
2011-10-18 |
Quest Pharmatech Inc. |
Combination therapy for treating disease
|
KR20020012292A
(ko)
*
|
1999-06-25 |
2002-02-15 |
제넨테크, 인크. |
항-ErbB 항체-메이탄시노이드 결합체를 사용한 치료방법
|
PL204629B1
(pl)
*
|
1999-06-25 |
2010-01-29 |
Genentech Inc |
Zastosowanie przeciwciała do wytwarzania leku do leczenia raka sutka, zastosowanie przeciwciała do leczenia raka jajnika, zastosowanie przeciwciała do wytwarzania leku do leczenia raka płuc i zastosowanie przeciwciała do leczenia raka okrężnicy, raka odbytnicy i raka jelita grubego i odbytu
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
US6825333B1
(en)
|
1999-08-20 |
2004-11-30 |
Chiron Corporation |
EGFH2 genes and gene products
|
DE60042693D1
(de)
|
1999-08-27 |
2009-09-17 |
Genentech Inc |
Dosierung für die behandlung mit anti erbb2-antikörpern
|
EP2289549A3
(en)
|
1999-10-01 |
2011-06-15 |
Immunogen, Inc. |
Immunoconjugates for treating cancer
|
DK1282443T3
(da)
|
2000-05-19 |
2010-01-04 |
Genentech Inc |
Gendetektionsassay til at forbedre sandsynligheden for et effektivt respons på en ErbB-antagonist cancerterapi
|
EP1228766A1
(en)
*
|
2001-01-31 |
2002-08-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
PYK2 phosphorylation by HER3 induces tumor invasion
|
GB2397018B
(en)
*
|
2001-10-26 |
2006-05-31 |
Altarex Medical Corp |
Combination therapy for treating disease
|
JP2005535297A
(ja)
*
|
2002-04-11 |
2005-11-24 |
アムジェン インコーポレイテッド |
Her−2レセプターチロシンキナーゼ分子およびその使用
|
ITTO20020340A1
(it)
*
|
2002-04-19 |
2003-10-20 |
Biother Di Contardi Gabriella |
Localizzazione del recettore her2 mediante anticorpo umanizzato biotinilato.
|
WO2003101401A2
(en)
|
2002-06-03 |
2003-12-11 |
Chiron Corporation |
Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
|
AT413486B
(de)
*
|
2002-07-03 |
2006-03-15 |
Igeneon Krebs Immuntherapie |
Verwendung eines antikörpers gerichtet gegen lewis-antigene
|
NO340576B1
(no)
*
|
2002-07-11 |
2017-05-15 |
Hoffmann La Roche |
Rekombinant, humanisert antistoff 2C4 (rhuMab 2C4) for anvendelse sammen med et andre, forskjellig vekstinhiberende anti-ErbB2-antistoff i en fremgangsmåte for behandling av kreft i en pasient og anvendelse derav for fremstilling av et medikament
|
MXPA05000403A
(es)
*
|
2002-07-15 |
2005-07-22 |
Genentech Inc |
Metodos para identificar tumores que responden al tratamiento con anticuerpos contra erbb2.
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
US7264800B2
(en)
|
2002-07-18 |
2007-09-04 |
Helix Biopharma Corporation |
Method and composition for inhibiting cancer cell growth
|
CA2872136C
(en)
|
2002-07-18 |
2017-06-20 |
Merus B.V. |
Recombinant production of mixtures of antibodies
|
EP1530482B9
(en)
*
|
2002-07-18 |
2014-04-16 |
Helix Biopharma Corp. |
Use of urease for inhibiting cancer cell growth
|
CA2494310A1
(en)
|
2002-08-01 |
2004-02-12 |
Immunomedics, Inc. |
Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
JP4790413B2
(ja)
*
|
2002-10-08 |
2011-10-12 |
イミューノメディクス、インコーポレイテッド |
抗体療法
|
JP4959136B2
(ja)
*
|
2002-12-13 |
2012-06-20 |
イミューノメディクス、インコーポレイテッド |
細胞内で開裂可能な結合を有する免疫接合体
|
CA2518716A1
(en)
*
|
2003-03-11 |
2005-01-13 |
Dana-Farber Cancer Institute |
Inhibition of viral pathogenesis
|
US7619070B2
(en)
*
|
2003-04-23 |
2009-11-17 |
Medarex, Inc. |
Humanized antibodies to interferon alpha receptor-1 (IFNAR-1)
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
AT500651B9
(de)
*
|
2003-05-27 |
2010-04-15 |
Altropus Gmbh |
Aktiv immunisierender antikörper
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
ES2408582T3
(es)
|
2003-05-30 |
2013-06-21 |
Merus B.V. |
Biblioteca de Fab para la preparación de una mezcla de anticuerpos
|
HUE050171T2
(hu)
|
2003-07-28 |
2020-11-30 |
Genentech Inc |
Protein-A kioldódásának csökkentése protein-A affinitáskromatográfia során
|
WO2005020923A2
(en)
*
|
2003-08-29 |
2005-03-10 |
Cedars-Sinai Medical Center |
Composition and method for the treatment of cancer and other physiologic conditions based on modulation of the ppar-gamma pathway and her-kinase axis
|
WO2005028498A2
(en)
*
|
2003-09-18 |
2005-03-31 |
Raven Biotechnologies, Inc. |
Kid3 and kid3 antibodies that bind thereto
|
JP2007512324A
(ja)
*
|
2003-11-28 |
2007-05-17 |
ミトラ、メディカル、アクチボラグ |
Erb抗原のターゲッティング
|
RU2402568C2
(ru)
*
|
2004-02-06 |
2010-10-27 |
МорфоСис АГ |
Человеческие анти-cd38-антитела и их применение
|
RU2273475C2
(ru)
*
|
2004-04-06 |
2006-04-10 |
Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) |
Способ лечения диссеминированного колоректального рака
|
EP2286844A3
(en)
*
|
2004-06-01 |
2012-08-22 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
GT200500155A
(es)
*
|
2004-06-16 |
2006-05-15 |
|
Terapia del càncer resistente al platino
|
KR20160096228A
(ko)
|
2004-07-22 |
2016-08-12 |
제넨테크, 인크. |
Her2 항체 조성물
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
CN104447992A
(zh)
|
2004-09-23 |
2015-03-25 |
健泰科生物技术公司 |
半胱氨酸改造的抗体和偶联物
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
BRPI0518086A
(pt)
*
|
2004-12-07 |
2008-10-28 |
Genentech Inc |
métodos para tratamento de cáncer, métodos de avaliação de fosforilação ou ativação de her e método de identificação
|
AR050418A1
(es)
|
2005-01-21 |
2006-10-25 |
Genentech Inc |
Dosificacion fija de anticuerpos her
|
EP2399605A1
(en)
|
2005-02-23 |
2011-12-28 |
Genentech, Inc. |
Extending time to disease progression or survival in cancer patients
|
AR053272A1
(es)
*
|
2005-05-11 |
2007-04-25 |
Hoffmann La Roche |
Determinacion de responsivos a la quimioterapia
|
US7858843B2
(en)
|
2005-06-06 |
2010-12-28 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
US7700299B2
(en)
|
2005-08-12 |
2010-04-20 |
Hoffmann-La Roche Inc. |
Method for predicting the response to a treatment
|
CA2619577A1
(en)
|
2005-08-15 |
2007-02-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
KR101164820B1
(ko)
|
2005-09-22 |
2012-07-12 |
삼성전자주식회사 |
디스플레이장치
|
US8080534B2
(en)
|
2005-10-14 |
2011-12-20 |
Phigenix, Inc |
Targeting PAX2 for the treatment of breast cancer
|
ZA200804162B
(en)
|
2005-11-21 |
2009-12-30 |
Genentech Inc |
Novel gene disruptions, compositions and methods relating thereto
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
US20080311107A1
(en)
|
2006-02-17 |
2008-12-18 |
Genetech, Inc. |
Novel Gene Disruptions, Compositions and Methods Relating Thereto
|
TW200812615A
(en)
|
2006-03-22 |
2008-03-16 |
Hoffmann La Roche |
Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2
|
AR060358A1
(es)
|
2006-04-06 |
2008-06-11 |
Novartis Vaccines & Diagnostic |
Quinazolinas para la inhibicion de pdk 1
|
WO2008036437A2
(en)
|
2006-04-19 |
2008-03-27 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
EP2032606B1
(en)
|
2006-05-30 |
2013-11-27 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
KR20090019890A
(ko)
*
|
2006-06-05 |
2009-02-25 |
제넨테크, 인크. |
Egf 또는 tgf-알파 수준이 상승된 암 환자의 생존 연장
|
ES2392630T3
(es)
|
2006-08-21 |
2012-12-12 |
F. Hoffmann-La Roche Ag |
Terapia antitumoral con anticuerpos anti-VEGF
|
WO2008031531A1
(en)
*
|
2006-09-15 |
2008-03-20 |
F. Hoffmann-La Roche Ag |
Tumor therapy with a combination of anti-her2 antibodies
|
KR101493779B1
(ko)
*
|
2006-10-12 |
2015-02-16 |
츄가이 세이야꾸 가부시키가이샤 |
항 ereg 항체를 이용하는 암의 진단 및 치료 방법
|
AU2007308792B2
(en)
|
2006-10-27 |
2013-01-24 |
Genentech, Inc. |
Antibodies and immunoconjugates and uses therefor
|
CN103432580A
(zh)
*
|
2007-03-02 |
2013-12-11 |
健泰科生物技术公司 |
基于低her3表达预测对her二聚化抑制剂的响应
|
WO2008154249A2
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
KR20100056438A
(ko)
*
|
2007-06-18 |
2010-05-27 |
메디뮨 엘엘씨 |
EphA2 및 ErbB2를 발현하는 세포의 상승적 치료 방법
|
CN101802012B
(zh)
|
2007-07-16 |
2014-08-06 |
健泰科生物技术公司 |
抗cd79b抗体和免疫偶联物及使用方法
|
RU2557319C2
(ru)
|
2007-07-16 |
2015-07-20 |
Дженентек, Инк. |
ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ CD79b И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ПРИМЕНЕНИЯ
|
CA2703279C
(en)
|
2007-10-30 |
2014-04-22 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
CA2705890A1
(en)
|
2007-11-27 |
2009-06-04 |
Michael John Scott Saunders |
Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
|
UY31545A1
(es)
|
2007-12-20 |
2009-08-03 |
|
Nuevos derivados de 2-carboxamida cianoaminourea, sus sales y profarmacos farmacéuticamente aceptables, procesos de preparacion y aplicaciones
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
WO2009088805A2
(en)
|
2008-01-03 |
2009-07-16 |
The Scripps Research Institute |
Antibody targeting through a modular recognition domain
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
BRPI0906435B8
(pt)
|
2008-01-31 |
2022-03-15 |
Genentech Inc |
Anticorpo anti-cd79b quimérico, composto conjugado, formulação farmacêutica, método para determinar a presença da proteína cd79b, ensaio para detectar células de câncer, método para inibir proliferação celular, usos de um anticorpo, de um composto conjugado e de uma formulação farmacêutica, e método para a fabricação de um composto conjugado
|
AU2009223124B2
(en)
|
2008-03-14 |
2015-03-26 |
Genentech, Inc. |
Genetic variations associated with drug resistance
|
PL3269366T3
(pl)
*
|
2008-03-18 |
2020-07-27 |
Genentech, Inc. |
Kombinacje koniugatu przeciwciało anty-HER2-lek i lapatinibu, i sposoby zastosowania
|
EP3170888A1
(en)
|
2008-05-23 |
2017-05-24 |
Siwa Corporation |
Methods and compositions for facilitating regeneration
|
BRPI0812682A2
(pt)
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
AU2009291865A1
(en)
|
2008-09-10 |
2010-03-18 |
Genentech, Inc. |
Compositions and methods for the prevention of oxidative degradation of proteins
|
DK3903829T3
(da)
|
2009-02-13 |
2023-06-26 |
Immunomedics Inc |
Immunkonjugater med en intracellulær spaltelig binding
|
TWI461211B
(zh)
|
2009-03-20 |
2014-11-21 |
Genentech Inc |
抗-her抗體
|
BRPI1012676A2
(pt)
|
2009-04-01 |
2016-04-05 |
Genentech Inc |
anticorpos anti-fcrh5 e imunoconjugados e métodos de uso
|
MX2011010158A
(es)
|
2009-04-07 |
2011-10-17 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-2/anti-c-met.
|
US20120141501A1
(en)
|
2009-05-29 |
2012-06-07 |
Forerunner Pharma Research Co. Ltd |
Pharmaceutical Composition Containing Antagonist of EGF Family Ligand as Component
|
JP5705836B2
(ja)
|
2009-05-29 |
2015-04-22 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Her2を発現する胃癌患者のher2シグナル伝達のためのモジュレーター
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
US8512983B2
(en)
|
2009-08-11 |
2013-08-20 |
Martin Gawlitzek |
Production of proteins in glutamine-free cell culture media
|
EP2464381A1
(en)
*
|
2009-08-15 |
2012-06-20 |
F. Hoffmann-La Roche AG |
Anti-angiogenesis therapy for the treatment of previously treated breast cancer
|
CN108409829A
(zh)
|
2009-09-01 |
2018-08-17 |
弗·哈夫曼-拉罗切有限公司 |
通过改进的a蛋白洗脱增强的蛋白质纯化
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
PL2486141T3
(pl)
|
2009-10-07 |
2018-07-31 |
Macrogenics, Inc. |
Polipeptydy zawierające regiony fc i mające w wyniku zmian w zakresie fukozylacji ulepszoną funkcję efektorową, i sposoby zastosowania tych polipeptydów
|
CA2777825A1
(en)
*
|
2009-10-28 |
2011-05-19 |
Abbott Biotherapeutics Corp. |
Anti-egfr antibodies and their uses
|
CA2780143A1
(en)
|
2009-11-05 |
2011-05-12 |
Genentech, Inc. |
Methods and composition for secretion of heterologous polypeptides
|
PL3351558T3
(pl)
|
2009-11-13 |
2020-08-24 |
Daiichi Sankyo Europe Gmbh |
Materiał i sposoby leczenia lub zapobiegania chorobom związanym z HER-3
|
MX2012006406A
(es)
|
2009-12-04 |
2012-07-25 |
Genentech Inc |
Anticuerpos multiespecificos, analogos de anticuerpo, composiciones y metodos.
|
US9115200B2
(en)
*
|
2010-02-04 |
2015-08-25 |
Toray Industries, Inc. |
Pharmaceutical composition for treating cancer using a monoclonal antibody having immunological reactivity with CAPRIN-1
|
US9556249B2
(en)
|
2010-02-18 |
2017-01-31 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
US8609095B2
(en)
|
2010-03-04 |
2013-12-17 |
Symphogen A/S |
Anti-HER2 antibodies and compositions
|
BR112012021873B8
(pt)
|
2010-03-22 |
2021-09-14 |
Genentech Inc |
composição de matéria, artigo de manufatura, métodos para preparar uma composição, para aumentar a estabilidade de uma proteína em solução aquosa livre de polissorbato e para prevenir ou reduzir a agregação de uma proteína em solução aquosa livre de polissorbato
|
KR20130060227A
(ko)
|
2010-05-03 |
2013-06-07 |
제넨테크, 인크. |
단백질-함유 제제의 점도 감소에 유용한 조성물 및 방법
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
NZ604003A
(en)
|
2010-05-27 |
2015-04-24 |
Genmab As |
Monoclonal antibodies against her2
|
NZ604007A
(en)
|
2010-05-27 |
2015-03-27 |
Genmab As |
Monoclonal antibodies against her2 epitope
|
PL2576580T3
(pl)
|
2010-05-28 |
2017-03-31 |
F.Hoffmann-La Roche Ag |
Zmniejszenie poziomu mleczanu i zwiększenie wytwarzania polipeptydu przez obniżenie poziomu ekspresji dehydrogenazy mleczanowej i kinazy dehydrogenazy pirogronianowej
|
SG185430A1
(en)
|
2010-06-03 |
2012-12-28 |
Genentech Inc |
Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
|
CN107335062B
(zh)
|
2010-06-08 |
2021-09-24 |
基因泰克公司 |
半胱氨酸改造的抗体和偶联物
|
SI3586826T1
(sl)
|
2010-06-24 |
2021-09-30 |
F. Hoffmann-La Roche Ag |
Sestavki in postopki za stabilizacijo formulacij, ki vsebujejo beljakovine
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
TW201302793A
(zh)
|
2010-09-03 |
2013-01-16 |
Glaxo Group Ltd |
新穎之抗原結合蛋白
|
US8721571B2
(en)
|
2010-11-22 |
2014-05-13 |
Siwa Corporation |
Selective removal of cells having accumulated agents
|
WO2012069466A1
(en)
|
2010-11-24 |
2012-05-31 |
Novartis Ag |
Multispecific molecules
|
BR112013012422A2
(pt)
|
2010-12-21 |
2016-08-30 |
Hoffmann La Roche |
"método para produzir uma preparação de anticorpo e anticorpo anti-her2"
|
WO2012085111A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
CN103384681B
(zh)
|
2010-12-23 |
2018-05-18 |
霍夫曼-拉罗奇有限公司 |
结合剂
|
EA025011B1
(ru)
|
2011-01-31 |
2016-11-30 |
Новартис Аг |
ПУРИНЫ, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR КИНАЗЫ, ИХ ИСПОЛЬЗОВАНИЕ И ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
|
WO2012122378A2
(en)
*
|
2011-03-08 |
2012-09-13 |
The Trustees Of The University Of Pennsylvania |
Antibody-like proteins for therapeutic and diagnostic use
|
AU2012245116A1
(en)
|
2011-04-20 |
2013-11-07 |
Genmab A/S |
Bispecific antibodies against HER2 and CD3
|
ES2704038T3
(es)
|
2011-05-24 |
2019-03-13 |
Zyngenia Inc |
Complejos multiespecíficos multivalentes y monovalentes y sus usos
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
DK2766040T3
(da)
|
2011-10-14 |
2019-07-22 |
Hoffmann La Roche |
Pertuzumab, trastuzumab, docetaxel og carboplatin til behandling af brystkræft i et tidligt stadie
|
WO2013063229A1
(en)
|
2011-10-25 |
2013-05-02 |
The Regents Of The University Of Michigan |
Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
|
PL2771342T3
(pl)
|
2011-10-28 |
2016-11-30 |
|
Nowe pochodne puryny i ich zastosowanie w leczeniu chorób
|
WO2013078191A1
(en)
|
2011-11-23 |
2013-05-30 |
Medimmune, Llc |
Binding molecules specific for her3 and uses thereof
|
RU2019103083A
(ru)
|
2011-11-30 |
2019-03-22 |
Дженентек, Инк. |
МУТАЦИИ ErbB3 ПРИ РАКЕ
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
SI2794635T1
(sl)
|
2011-12-22 |
2018-12-31 |
F. Hoffmann-La Roche Ag |
Ionskoizmenjevalna membranska kromatografija
|
TWI593705B
(zh)
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
WO2013113796A1
(en)
|
2012-01-31 |
2013-08-08 |
Smithkline Beecham (Cork) Limited |
Method of treating cancer
|
EP2638916A1
(en)
|
2012-03-16 |
2013-09-18 |
Covagen AG |
Novel binding molecules with antitumoral activity
|
WO2013148315A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
EA202090591A3
(ru)
|
2012-04-20 |
2020-12-30 |
Мерюс Н.В. |
СПОСОБЫ И СРЕДСТВА ДЛЯ ПОЛУЧЕНИЯ Ig-ПОДОБНЫХ МОЛЕКУЛ
|
KR101505157B1
(ko)
|
2012-05-08 |
2015-03-24 |
주식회사 종근당 |
항―ErbB2 항체 변이체
|
US10213432B2
(en)
|
2012-05-16 |
2019-02-26 |
Novartis Ag |
Dosage regimen for a PI-3 kinase inhibitor
|
CA2889298C
(en)
|
2012-11-30 |
2024-01-02 |
Anton Belousov |
Identification of patients in need of pd-l1 inhibitor cotherapy
|
WO2014108858A1
(en)
|
2013-01-10 |
2014-07-17 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Fatty acid synthase inhibitors
|
US9180185B2
(en)
|
2013-01-11 |
2015-11-10 |
Hoffman-La Roche Inc. |
Combination therapy of anti-HER3 antibodies
|
EA038918B1
(ru)
|
2013-03-15 |
2021-11-09 |
Зинджения, Инк. |
Пептид, связывающий рецептор эпидермального фактора роста, мультиспецифические комплексы, содержащие пептид и антитела, и их применение
|
CN104628846B
(zh)
|
2013-11-06 |
2019-12-06 |
三生国健药业(上海)股份有限公司 |
重组蛋白质的纯化方法
|
CN110240655B
(zh)
|
2013-11-19 |
2023-05-16 |
荣昌生物制药(烟台)股份有限公司 |
抗her2抗体及其缀合物
|
DK3074424T3
(da)
|
2013-11-27 |
2025-05-19 |
Zymeworks Bc Inc |
Bispecifikke antigenbindende konstrukter målrettet her2
|
PL3076969T3
(pl)
|
2013-12-06 |
2022-01-17 |
Novartis Ag |
Schemat dawkowania selektywnego inhibitora 3-kinazy fosfatydynozytolu alfa-izoformy
|
EP3101032B1
(en)
|
2014-01-31 |
2019-01-16 |
Daiichi Sankyo Company, Limited |
Anti-her2 antibody-drug conjugate
|
US20160361309A1
(en)
|
2014-02-26 |
2016-12-15 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Methods of treating cancer patients responding to ezh2 inhibitor gsk126
|
CA2941687A1
(en)
|
2014-03-14 |
2015-09-17 |
Genentech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
RU2016144176A
(ru)
|
2014-04-11 |
2018-05-14 |
МЕДИММЬЮН, ЭлЭлСи |
Биспецифические антитела к her2
|
EP3388449A3
(en)
|
2014-09-12 |
2018-10-24 |
F. Hoffmann-La Roche AG |
Cysteine engineered antibodies and conjugates
|
MX391802B
(es)
|
2014-09-19 |
2025-03-11 |
Siwa Corp |
Anticuerpos anti-age para el tratamiento de inflamación y trastornos autoinmunes
|
US10385380B2
(en)
|
2014-10-02 |
2019-08-20 |
The Regents Of The University Of California |
Personalized protease assay to measure protease activity in neoplasms
|
WO2016082044A1
(en)
|
2014-11-27 |
2016-06-02 |
Zymeworks Inc. |
Methods of using bispecific antigen-binding constructs targeting her2
|
US10358502B2
(en)
|
2014-12-18 |
2019-07-23 |
Siwa Corporation |
Product and method for treating sarcopenia
|
US9993535B2
(en)
|
2014-12-18 |
2018-06-12 |
Siwa Corporation |
Method and composition for treating sarcopenia
|
MA41414A
(fr)
|
2015-01-28 |
2017-12-05 |
Centre Nat Rech Scient |
Protéines de liaison agonistes d' icos
|
KR101515535B1
(ko)
|
2015-01-28 |
2015-05-06 |
주식회사 종근당 |
항―ErbB2 항체 변이체
|
US11028182B2
(en)
|
2015-05-13 |
2021-06-08 |
Zymeworks Inc. |
Antigen-binding constructs targeting HER2
|
EP3331919A1
(en)
|
2015-08-07 |
2018-06-13 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
AU2016336959A1
(en)
*
|
2015-10-13 |
2018-04-12 |
Siwa Corporation |
Anti-age antibodies and methods of use thereof
|
CN108472289A
(zh)
|
2015-11-02 |
2018-08-31 |
诺华股份有限公司 |
磷脂酰肌醇3-激酶抑制剂的给药方案
|
CN106729743B
(zh)
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
EP3383907B1
(en)
|
2015-12-01 |
2022-02-23 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
CR20180318A
(es)
|
2015-12-14 |
2018-09-19 |
Macrogenics Inc |
Moléculas biespecíficas que tienen inmunorreactividad con pd-1 y ctla-4, y métodos de uso de las mismas
|
CN105646704B
(zh)
*
|
2015-12-28 |
2019-11-15 |
广西医科大学 |
抗p185erbB2人鼠嵌合抗体ChAb26、乳腺特异性表达载体、转基因FVB小鼠及其制备方法
|
HUE058854T2
(hu)
|
2016-02-19 |
2022-09-28 |
Siwa Corp |
Módszer és készítmény a rák kezelésére, az áttétes rákos sejtek elpusztítására és a rák áttétképzõdésének megelõzésére a fejlett glikációs végtermékek (AGE) elleni antitest alkalmazásával
|
JP2019508428A
(ja)
*
|
2016-03-15 |
2019-03-28 |
メリマック ファーマシューティカルズ インコーポレーティッド |
抗erbb3抗体を含む組み合わせ療法を用いて、er+、her2−、hrg+乳癌を治療するための方法
|
US11958900B2
(en)
|
2016-04-15 |
2024-04-16 |
Siwa Corporation |
Anti-age antibodies for treating neurodegenerative disorders
|
EP3454863A1
(en)
|
2016-05-10 |
2019-03-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
SG11201810032PA
(en)
*
|
2016-05-12 |
2018-12-28 |
Agency Science Tech & Res |
Anti-erbb-2 antibodies and uses thereof
|
EP3475306A1
(en)
|
2016-06-23 |
2019-05-01 |
Siwa Corporation |
Vaccines for use in treating various diseases and disorders
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
CN109789211A
(zh)
|
2016-10-07 |
2019-05-21 |
第一三共株式会社 |
基于抗her2抗体-药物偶联物施予的耐性癌的治疗
|
BR112019011794A2
(pt)
|
2016-12-12 |
2019-10-29 |
Daiichi Sankyo Co Ltd |
composição farmacêutica, e, método terapêutico.
|
JP7069476B2
(ja)
*
|
2017-01-06 |
2022-05-18 |
博奥信生物技▲術▼(南京)有限公司 |
ErbB2抗体およびその使用
|
US10858449B1
(en)
|
2017-01-06 |
2020-12-08 |
Siwa Corporation |
Methods and compositions for treating osteoarthritis
|
US10961321B1
(en)
|
2017-01-06 |
2021-03-30 |
Siwa Corporation |
Methods and compositions for treating pain associated with inflammation
|
US10925937B1
(en)
|
2017-01-06 |
2021-02-23 |
Siwa Corporation |
Vaccines for use in treating juvenile disorders associated with inflammation
|
US10995151B1
(en)
|
2017-01-06 |
2021-05-04 |
Siwa Corporation |
Methods and compositions for treating disease-related cachexia
|
SG11201907753TA
(en)
|
2017-02-24 |
2019-09-27 |
Macrogenics Inc |
Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
|
KR20220100996A
(ko)
|
2017-03-02 |
2022-07-18 |
제넨테크, 인크. |
Her2-양성 유방암 어쥬번트 치료
|
EP3589286B1
(en)
|
2017-03-02 |
2022-08-03 |
ASLAN Pharmaceuticals Pte Ltd |
Dhodh inhibitor for treating haematological cancer
|
BR112019019706A2
(pt)
|
2017-03-22 |
2020-04-28 |
Genentech Inc |
conjugado de anticorpo, anticorpo, composição farmacêutica, métodos para reduzir ou inibir angiogênese e para tratar um distúrbio ocular
|
JP2020516648A
(ja)
|
2017-04-13 |
2020-06-11 |
シワ コーポレーション |
ヒト化モノクローナル終末糖化産物抗体
|
WO2018222135A1
(en)
|
2017-06-02 |
2018-12-06 |
Aslan Pharmaceuticals Pte Ltd |
Cancer therapy
|
CN107417791B
(zh)
*
|
2017-08-17 |
2020-09-22 |
合肥瀚科迈博生物技术有限公司 |
抗人ErbB2双特异性抗体、其制备方法及用途
|
KR20200044044A
(ko)
|
2017-08-23 |
2020-04-28 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트의 제제 및 그 동결 건조 방법
|
KR20250084239A
(ko)
|
2017-08-31 |
2025-06-10 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트의 개량 제조 방법
|
JP7248578B2
(ja)
|
2017-08-31 |
2023-03-29 |
第一三共株式会社 |
抗体-薬物コンジュゲートの新規製造方法
|
CN107789631B
(zh)
*
|
2017-11-03 |
2021-03-16 |
合肥瀚科迈博生物技术有限公司 |
抗人ErbB2双表位抗体-药物偶联物及其应用
|
SG11202005557TA
(en)
|
2017-12-12 |
2020-07-29 |
Macrogenics Inc |
Bispecific cd 16-binding molecules and their use in the treatment of disease
|
US11518801B1
(en)
|
2017-12-22 |
2022-12-06 |
Siwa Corporation |
Methods and compositions for treating diabetes and diabetic complications
|
SG11202007572VA
(en)
|
2018-02-15 |
2020-09-29 |
Macrogenics Inc |
Variant cd3-binding domains and their use in combination therapies for the treatment of disease
|
EP3560945A1
(en)
|
2018-04-27 |
2019-10-30 |
F. Hoffmann-La Roche AG |
Methods for purification of polypeptides using polysorbates
|
KR20250105480A
(ko)
|
2018-05-28 |
2025-07-08 |
다이이찌 산쿄 가부시키가이샤 |
항 her2 항체-약물 콘쥬게이트 투여에 의한 her2 변이암의 치료
|
IL280301B2
(en)
|
2018-07-23 |
2025-06-01 |
Trevi Therapeutics Inc |
Treatment of chronic cough, breathlessness and dyspnea
|
SG11202100653YA
(en)
|
2018-07-25 |
2021-02-25 |
Daiichi Sankyo Co Ltd |
Effective method for manufacturing antibody-drug conjugate
|
EP3831853A4
(en)
|
2018-07-27 |
2022-06-01 |
Daiichi Sankyo Company, Limited |
Protein recognizing drug moiety of antibody-drug conjugate
|
JP7473474B2
(ja)
|
2018-07-31 |
2024-04-23 |
第一三共株式会社 |
抗体-薬物コンジュゲート投与による転移性脳腫瘍の治療
|
EP3834843A4
(en)
|
2018-08-06 |
2022-05-11 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and tubulin inhibitor
|
JP7481255B2
(ja)
|
2018-08-23 |
2024-05-10 |
第一三共株式会社 |
抗体薬物複合体の感受性マーカー
|
KR20210064325A
(ko)
|
2018-09-25 |
2021-06-02 |
에이비에스씨아이, 엘엘씨 |
단백질 정제 방법
|
WO2020084503A1
(en)
|
2018-10-26 |
2020-04-30 |
Cadila Healthcare Limited |
A composition comprising antibody with reduced level of basic variants thereof
|
SG11202106248XA
(en)
|
2018-12-11 |
2021-07-29 |
Daiichi Sankyo Co Ltd |
Combination of antibody-drug conjugate with parp inhibitor
|
MA54544A
(fr)
|
2018-12-19 |
2021-10-27 |
Incyte Corp |
Inhibiteurs de la voie jak1 pour le traitement d'une maladie gastro-intestinale
|
KR20210107069A
(ko)
|
2018-12-21 |
2021-08-31 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 컨쥬게이트와 키나아제 저해제의 조합
|
EP3917963A1
(en)
|
2019-02-01 |
2021-12-08 |
GlaxoSmithKline Intellectual Property Development Limited |
Belantamab mafodotin in combination with pembrolizumab for treating cancer
|
CN113660953A
(zh)
|
2019-04-01 |
2021-11-16 |
豪夫迈·罗氏有限公司 |
用于稳定含蛋白质制剂的组合物和方法
|
CN112007169B
(zh)
*
|
2019-05-30 |
2022-03-08 |
湖南大学 |
一种核酸适配体药物偶联物及其制备方法和用途
|
CN110205302B
(zh)
*
|
2019-06-24 |
2021-03-23 |
扬州大学 |
一株分泌抗麦考酚酸单克隆抗体的细胞株、其单克隆抗体及其应用
|
BR112021025476A2
(pt)
|
2019-06-26 |
2022-10-11 |
Glaxosmithkline Ip Dev Ltd |
Proteínas de ligação à il1rap
|
CN110551214A
(zh)
*
|
2019-08-27 |
2019-12-10 |
杨澜 |
一种人源化抗Periostin单克隆抗体、及其制备方法和应用
|
CA3166928A1
(en)
|
2020-01-10 |
2021-07-15 |
Trevi Therapeutics, Inc. |
Methods of administering nalbuphine
|
EP4096718A1
(en)
|
2020-01-28 |
2022-12-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
US20230233540A1
(en)
|
2020-06-24 |
2023-07-27 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and cdk9 inhibitor
|
CN116194109A
(zh)
|
2020-06-24 |
2023-05-30 |
阿斯利康(英国)有限公司 |
抗体-药物缀合物和atm抑制剂的组合
|
WO2021260582A1
(en)
|
2020-06-24 |
2021-12-30 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and aurora b inhibitor
|
WO2021260583A1
(en)
|
2020-06-24 |
2021-12-30 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and dna-pk inhibitor
|
KR20230043109A
(ko)
|
2020-06-24 |
2023-03-30 |
아스트라제네카 유케이 리미티드 |
항체-약물 접합체 및 atr 억제제의 조합
|
US20230293714A1
(en)
|
2020-07-20 |
2023-09-21 |
Daiichi Sankyo Company, Limited |
Combination of anti-her2 antibody-drug conjugate with her dimerization inhibitor
|
CA3195117A1
(en)
|
2020-10-09 |
2022-04-14 |
Jerome Thomas Mettetal Ii |
Combination of antibody-drug conjugate and parp1 selective inhibitor
|
BR112023008845A2
(pt)
|
2020-11-11 |
2023-10-03 |
Daiichi Sankyo Co Ltd |
Composição farmacêutica, e, método de tratamento
|
US20250034274A1
(en)
|
2021-11-30 |
2025-01-30 |
Daiichi Sankyo Company , Limited |
Protease-cleavable masked antibodies
|
TW202333800A
(zh)
|
2021-12-28 |
2023-09-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及rasg12c抑制劑之組合
|
TW202342106A
(zh)
|
2022-02-09 |
2023-11-01 |
日商第一三共股份有限公司 |
環境應答性遮蔽抗體及其利用
|
US20250276079A1
(en)
|
2022-04-27 |
2025-09-04 |
Daiichi Sankyo Company, Limited |
COMBINATION OF ANTIBODY-DRUG CONJUGATE WITH EZH1 and/or EZH2 INHIBITOR
|
US20250296966A1
(en)
|
2022-05-11 |
2025-09-25 |
Daiichi Sankyo Company, Limited |
Combination of an antibody specific for a tumor antigen and a cd47 inhibitor
|
AU2023313120A1
(en)
|
2022-07-28 |
2025-02-06 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and bispecific checkpoint inhibitor
|
WO2025088496A1
(en)
|
2023-10-24 |
2025-05-01 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and anti-pd-1/tim-3 bispecific binding protein
|
CN117224689B
(zh)
*
|
2023-11-16 |
2024-02-23 |
上海复宏汉霖生物技术股份有限公司 |
联合抗her2抗体和化疗剂治疗胃癌的用途
|
WO2025120513A1
(en)
|
2023-12-05 |
2025-06-12 |
Astrazeneca Uk Limited |
Combination of antibody-drug conjugate and blood brain barrier-penetrant parp1 selective inhibitor
|