AU2013271677B2 - Polymer coatings - Google Patents

Polymer coatings Download PDF

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Publication number
AU2013271677B2
AU2013271677B2 AU2013271677A AU2013271677A AU2013271677B2 AU 2013271677 B2 AU2013271677 B2 AU 2013271677B2 AU 2013271677 A AU2013271677 A AU 2013271677A AU 2013271677 A AU2013271677 A AU 2013271677A AU 2013271677 B2 AU2013271677 B2 AU 2013271677B2
Authority
AU
Australia
Prior art keywords
polymer
substrate
polymer coating
beads
functional groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2013271677A
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English (en)
Other versions
AU2013271677A1 (en
Inventor
Daniel Bratton
Andrew A. Brown
Wayne N. GEORGE
Hongji Ren
Ryan C. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Illumina Inc
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of AU2013271677A1 publication Critical patent/AU2013271677A1/en
Application granted granted Critical
Publication of AU2013271677B2 publication Critical patent/AU2013271677B2/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/24—Homopolymers or copolymers of amides or imides
    • C09D133/26—Homopolymers or copolymers of acrylamide or methacrylamide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/06—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/06—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation
    • B05D3/061—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to radiation using U.V.
    • B05D3/065—After-treatment
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D135/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least another carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24802—Discontinuous or differential coating, impregnation or bond [e.g., artwork, printing, retouched photograph, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24802—Discontinuous or differential coating, impregnation or bond [e.g., artwork, printing, retouched photograph, etc.]
    • Y10T428/24917—Discontinuous or differential coating, impregnation or bond [e.g., artwork, printing, retouched photograph, etc.] including metal layer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24802—Discontinuous or differential coating, impregnation or bond [e.g., artwork, printing, retouched photograph, etc.]
    • Y10T428/24926—Discontinuous or differential coating, impregnation or bond [e.g., artwork, printing, retouched photograph, etc.] including ceramic, glass, porcelain or quartz layer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31536—Including interfacial reaction product of adjacent layers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
    • Y10T428/31935—Ester, halide or nitrile of addition polymer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Plasma & Fusion (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Laminated Bodies (AREA)
  • Paints Or Removers (AREA)
  • Surface Treatment Of Glass (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
AU2013271677A 2012-06-08 2013-06-05 Polymer coatings Active AU2013271677B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261657508P 2012-06-08 2012-06-08
US61/657,508 2012-06-08
US201361753833P 2013-01-17 2013-01-17
US61/753,833 2013-01-17
US13/784,368 US9012022B2 (en) 2012-06-08 2013-03-04 Polymer coatings
US13/784,368 2013-03-04
PCT/US2013/044305 WO2013184796A1 (en) 2012-06-08 2013-06-05 Polymer coatings

Publications (2)

Publication Number Publication Date
AU2013271677A1 AU2013271677A1 (en) 2015-01-29
AU2013271677B2 true AU2013271677B2 (en) 2015-05-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013271677A Active AU2013271677B2 (en) 2012-06-08 2013-06-05 Polymer coatings

Country Status (14)

Country Link
US (7) US9012022B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP3792320A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (3) JP5859172B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR101559983B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN104508060B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2013271677B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2875671C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK2859055T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2859823T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL236023B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014DN11101A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL2859055T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT2859055T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2013184796A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (209)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8383345B2 (en) 2008-09-12 2013-02-26 University Of Washington Sequence tag directed subassembly of short sequencing reads into long sequencing reads
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
HUE026666T2 (en) 2010-04-05 2016-07-28 Prognosys Biosciences Inc Spatially encoded biological assays
US9074251B2 (en) 2011-02-10 2015-07-07 Illumina, Inc. Linking sequence reads using paired code tags
CN103443338B (zh) 2011-02-02 2017-09-22 华盛顿大学商业化中心 大规模平行邻接作图
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
CA2856163C (en) 2011-10-28 2019-05-07 Illumina, Inc. Microarray fabrication system and method
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
US8895249B2 (en) 2012-06-15 2014-11-25 Illumina, Inc. Kinetic exclusion amplification of nucleic acid libraries
WO2014060483A1 (en) 2012-10-17 2014-04-24 Spatial Transcriptomics Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
US9683230B2 (en) 2013-01-09 2017-06-20 Illumina Cambridge Limited Sample preparation on a solid support
US9512422B2 (en) 2013-02-26 2016-12-06 Illumina, Inc. Gel patterned surfaces
EP2970951B1 (en) 2013-03-13 2019-02-20 Illumina, Inc. Methods for nucleic acid sequencing
US20160023208A1 (en) 2013-03-13 2016-01-28 Illumina, Inc. Multilayer fluidic devices and methods for their fabrication
US9193998B2 (en) 2013-03-15 2015-11-24 Illumina, Inc. Super resolution imaging
US20140274747A1 (en) 2013-03-15 2014-09-18 Illumina, Inc. Super resolution imaging
CN105849275B (zh) 2013-06-25 2020-03-17 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
IL273519B2 (en) 2013-07-01 2023-04-01 Illumina Inc Surface activation and polymer assembly without a catalyst
US9193999B2 (en) 2013-07-03 2015-11-24 Illumina, Inc. Sequencing by orthogonal synthesis
AU2014312043A1 (en) 2013-08-30 2016-02-25 Illumina France Manipulation of droplets on hydrophilic or variegated-hydrophilic surfaces
US10540783B2 (en) 2013-11-01 2020-01-21 Illumina, Inc. Image analysis useful for patterned objects
EP3084523B1 (en) * 2013-12-19 2019-07-03 Illumina, Inc. Substrates comprising nano-patterning surfaces and methods of preparing thereof
DK3083994T3 (da) 2013-12-20 2021-09-13 Illumina Inc Bevarelse af genomisk konnektivitetsinformation i fragmenterede genomiske DNA-prøver
KR102333635B1 (ko) 2013-12-23 2021-11-30 일루미나, 인코포레이티드 광 방출의 검출을 개선시키기 위한 구조화 기판 및 이와 관련한 방법
US10156572B2 (en) 2014-02-18 2018-12-18 Arizona Board Of Regents On Behalf Of Arizona State University Three arm Y-shaped bisbiotin ligand
CN106536734B (zh) 2014-05-16 2020-12-22 Illumina公司 核酸合成技术
RU2682546C2 (ru) 2014-05-27 2019-03-19 Иллумина, Инк. Системы и способы биохимического анализа, включающие основной прибор и съемный картридж
EP3669985B1 (en) 2014-06-05 2022-02-02 Illumina, Inc. Systems including a rotary valve for at least one of sample preparation or sample analysis
SG11201610910QA (en) 2014-06-30 2017-01-27 Illumina Inc Methods and compositions using one-sided transposition
CN107076739B (zh) 2014-08-21 2018-12-25 伊卢米纳剑桥有限公司 可逆表面官能化
US10633694B2 (en) 2014-09-12 2020-04-28 Illumina, Inc. Compositions, systems, and methods for detecting the presence of polymer subunits using chemiluminescence
CA2960721C (en) 2014-10-09 2023-09-05 Illumina, Inc. Method and device for separating immiscible liquids to effectively isolate at least one of the liquids
US11873480B2 (en) 2014-10-17 2024-01-16 Illumina Cambridge Limited Contiguity preserving transposition
AU2015340767B2 (en) * 2014-10-31 2020-01-30 Illumina Cambridge Limited Novel polymers and DNA copolymer coatings
KR102590448B1 (ko) * 2014-11-11 2023-10-17 일루미나 케임브리지 리미티드 핵산의 모노클로날 클러스터를 형성시키고 시퀀싱하기 위한 방법 및 어레이
CN107223161B (zh) 2014-12-15 2022-03-22 亿明达股份有限公司 用于基底上的单分子放置的组合物和方法
CA2982146A1 (en) 2015-04-10 2016-10-13 Spatial Transcriptomics Ab Spatially distinguished, multiplex nucleic acid analysis of biological specimens
CN112229834B (zh) 2015-04-14 2024-11-26 亿明达股份有限公司 用于改进对光发射的检测的结构化基底及涉及其的方法
KR102333255B1 (ko) 2015-05-11 2021-12-01 일루미나, 인코포레이티드 치료제의 발견 및 분석을 위한 플랫폼
US10590464B2 (en) 2015-05-29 2020-03-17 Illumina Cambridge Limited Enhanced utilization of surface primers in clusters
US10808282B2 (en) 2015-07-07 2020-10-20 Illumina, Inc. Selective surface patterning via nanoimprinting
ES2945607T3 (es) * 2015-07-17 2023-07-04 Illumina Inc Láminas de polímero para aplicaciones de secuenciación
CN107771223B (zh) 2015-07-30 2022-03-22 亿明达股份有限公司 核苷酸的正交去封闭
US11512348B2 (en) 2015-08-14 2022-11-29 Illumina, Inc. Systems and methods using magnetically-responsive sensors for determining a genetic characteristic
WO2017123533A1 (en) 2016-01-11 2017-07-20 Illumina, Inc. Detection apparatus having a microfluorometer, a fluidic system, and a flow cell latch clamp module
CN110702652A (zh) 2016-03-24 2020-01-17 伊鲁米那股份有限公司 在发光成像中使用的设备和组成物及其使用方法
EP3377226B1 (en) 2016-03-28 2021-02-17 Illumina, Inc. Multi-plane microarrays
US11579336B2 (en) 2016-04-22 2023-02-14 Illumina, Inc. Photonic structure-based devices and compositions for use in luminescent imaging of multiple sites within a pixel, and methods of using the same
SG11201809376WA (en) 2016-05-18 2018-12-28 Illumina Inc Self assembled patterning using patterned hydrophobic surfaces
US10385214B2 (en) 2016-09-30 2019-08-20 Illumina Cambridge Limited Fluorescent dyes and their uses as biomarkers
ES2937782T3 (es) 2016-10-03 2023-03-31 Illumina Inc Detección fluorescente de aminas e hidrazinas y métodos de ensayo de las mismas
KR102624409B1 (ko) 2016-12-22 2024-01-11 일루미나, 인코포레이티드 품질 제어 트레이서를 갖는 어레이
IL267443B2 (en) 2016-12-22 2023-10-01 Illumina Inc Imprinting apparatus
CA3046659A1 (en) 2016-12-22 2018-06-28 Illumina, Inc. Flow cell package and method for making the same
MX2019006705A (es) 2016-12-22 2019-11-08 Illumina Inc Arreglos que incluyen una película de resina y una capa de polímero con patrón.
MX2019006616A (es) 2016-12-22 2019-10-24 Illumina Inc Arreglo que incluye cebador secuenciador y entidad no secuenciadora.
EP4257596A3 (en) 2016-12-22 2023-12-06 Illumina Cambridge Limited Coumarin compounds and their uses as fluorescent labels
GB201704754D0 (en) 2017-01-05 2017-05-10 Illumina Inc Kinetic exclusion amplification of nucleic acid libraries
CA3050852C (en) 2017-01-20 2021-03-09 Omniome, Inc. Genotyping by polymerase binding
CA3050241C (en) 2017-01-20 2022-11-29 Omniome, Inc. Allele-specific capture of nucleic acids
GB201701689D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials of non-closed shapes
GB201701688D0 (en) 2017-02-01 2017-03-15 Illumia Inc System and method with fiducials in non-recliner layouts
GB201701691D0 (en) 2017-02-01 2017-03-15 Illumina Inc System and method with reflective fiducials
GB201701686D0 (en) 2017-02-01 2017-03-15 Illunina Inc System & method with fiducials having offset layouts
SG11201906442TA (en) 2017-02-01 2019-08-27 Illumina Inc System and method with fiducials responding to multiple excitation frequencies
NL2019044B1 (en) 2017-05-11 2018-11-15 Illumina Inc Protective surface coatings for flow cells
FI3662083T3 (fi) 2017-08-01 2024-11-20 Illumina Inc Geneettisen materiaalin ja kirjastovalmisteen spatiaalinen indeksointi hydrogeelihelmiä ja virtauskennoja käyttämällä
GB201716931D0 (en) 2017-10-16 2017-11-29 Illumina Cambridge Ltd New fluorescent compounds and their use as biomarkers
NZ759626A (en) 2017-12-21 2023-03-31 Illumina Inc Flow cells with hydrogel coating
CA3067227C (en) * 2017-12-22 2023-07-18 Illumina, Inc. Catalytically active substances
BR112019027944A2 (pt) 2018-05-15 2020-12-01 Illumina, Inc. composições e métodos para clivagem química e desproteção de oligonucleotídeos ligados à superfície
US10495443B1 (en) 2018-07-26 2019-12-03 Qiagen Sciences, Llc Fiducial marking system
CN109111541B (zh) * 2018-08-20 2020-08-04 江南大学 一种含叠氮基高分子聚合物的制备方法
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
US20210317524A1 (en) 2018-08-28 2021-10-14 10X Genomics, Inc. Resolving spatial arrays
US20210332425A1 (en) 2018-08-28 2021-10-28 Rajiv Bharadwaj Increasing spatial array resolution
KR20250134701A (ko) * 2018-10-26 2025-09-11 일루미나, 인코포레이티드 Dna 가공을 위한 중합체 비드의 조절
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US10876148B2 (en) * 2018-11-14 2020-12-29 Element Biosciences, Inc. De novo surface preparation and uses thereof
US20200149095A1 (en) * 2018-11-14 2020-05-14 Element Biosciences, Inc. Low binding supports for improved solid-phase dna hybridization and amplification
SG11202012762WA (en) 2018-12-05 2021-01-28 Illumina Cambridge Ltd Methods and compositions for cluster generation by bridge amplification
WO2020123319A2 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Methods of using master / copy arrays for spatial detection
WO2020131354A1 (en) * 2018-12-17 2020-06-25 Illumina, Inc. Flow cells and sequencing kits
US12297565B2 (en) 2018-12-17 2025-05-13 Illumina, Inc. Methods and means for preparing a library for sequencing
KR20210104556A (ko) * 2018-12-18 2021-08-25 일루미나 케임브리지 리미티드 헤테로사이클릭 아지드 단위 및 이의 폴리머 코팅에서의 용도
AU2019411272B2 (en) 2018-12-18 2025-08-14 Illumina Cambridge Limited Methods and compositions for paired end sequencing using a single surface primer
AU2019402925B2 (en) 2018-12-19 2025-09-25 Illumina, Inc. Methods for improving polynucleotide cluster clonality priority
US11293061B2 (en) 2018-12-26 2022-04-05 Illumina Cambridge Limited Sequencing methods using nucleotides with 3′ AOM blocking group
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
CA3103807A1 (en) * 2019-01-14 2020-07-23 Illumina, Inc. Flow cell including a heteropolymer
TWI857000B (zh) 2019-01-29 2024-10-01 美商伊路米納有限公司 流體槽以及將複合物引入至流體槽之方法
TWI857001B (zh) 2019-01-29 2024-10-01 美商伊路米納有限公司 定序套組
CN114174531A (zh) 2019-02-28 2022-03-11 10X基因组学有限公司 用空间条码化寡核苷酸阵列对生物分析物进行概况分析
US12110546B2 (en) 2019-03-01 2024-10-08 Illumina Cambridge Limited Tertiary amine substituted coumarin compounds and uses as fluorescent labels
BR112020026528B1 (pt) 2019-03-01 2024-02-15 Illumina Cambridge Limited Composto de cumarina substituído com amina exocíclica, nucleotídeo ou oligonucleotídeo, kit, método de sequenciamento e método para sintetizar o referido composto
NL2023327B1 (en) 2019-03-01 2020-09-17 Illumina Inc Multiplexed fluorescent detection of analytes
WO2020178231A1 (en) 2019-03-01 2020-09-10 Illumina, Inc. Multiplexed fluorescent detection of analytes
EP3938538A1 (en) 2019-03-15 2022-01-19 10X Genomics, Inc. Methods for using spatial arrays for single cell sequencing
EP3887542A1 (en) 2019-03-22 2021-10-06 10X Genomics, Inc. Three-dimensional spatial analysis
US11421271B2 (en) 2019-03-28 2022-08-23 Illumina Cambridge Limited Methods and compositions for nucleic acid sequencing using photoswitchable labels
CN110055318A (zh) * 2019-05-06 2019-07-26 南京拓远生物科技有限公司 一种基于点击化学的三维dna微阵列表面的制备方法
SG11202012799UA (en) 2019-05-31 2021-01-28 Illumina Inc Storage device, system, and method
SG11202012810TA (en) 2019-05-31 2021-01-28 Illumina Inc System and method for storage
EP3976826A4 (en) 2019-05-31 2023-08-23 Illumina, Inc. SYSTEMS AND METHODS FOR STORAGE AND RETRIEVAL OF INFORMATION USING CELL STREAM
CN112689682A (zh) 2019-05-31 2021-04-20 伊鲁米纳公司 从流动池中的生物样品获取信息
CN112673251A (zh) 2019-05-31 2021-04-16 伊鲁米那股份有限公司 核苷酸选择性沉积或激活的流通池
WO2020243077A1 (en) 2019-05-31 2020-12-03 Illumina, Inc. Flow cell with one or more barrier features
US11377655B2 (en) 2019-07-16 2022-07-05 Pacific Biosciences Of California, Inc. Synthetic nucleic acids having non-natural structures
PH12021551557A1 (en) * 2019-08-01 2022-04-11 Illumina Inc Flow cells
TW202120693A (zh) * 2019-08-21 2021-06-01 美商伊路米納有限公司 偵測核苷酸之聚合酶併入的方法
EP4038546B1 (en) 2019-10-01 2024-08-21 10X Genomics, Inc. Systems and methods for identifying morphological patterns in tissue samples
WO2021091611A1 (en) 2019-11-08 2021-05-14 10X Genomics, Inc. Spatially-tagged analyte capture agents for analyte multiplexing
WO2021102003A1 (en) 2019-11-18 2021-05-27 10X Genomics, Inc. Systems and methods for tissue classification
EP4062373B1 (en) 2019-11-21 2025-01-22 10X Genomics, Inc. Spatial analysis of analytes
CA3158891A1 (en) 2019-11-22 2021-05-27 Neil Ira WEISENFELD Systems and methods for spatial analysis of analytes using fiducial alignment
AU2020389779A1 (en) 2019-11-27 2022-05-26 Illumina Cambridge Limited Cyclooctatetraene containing dyes and compositions
JP7607580B2 (ja) 2019-12-16 2024-12-27 イルミナ インコーポレイテッド キット及びフローセル
EP4081662A1 (en) * 2019-12-23 2022-11-02 Illumina, Inc. Nanoparticle with single site for template polynucleotide attachment
CN111171228B (zh) * 2020-01-20 2022-03-08 赛纳生物科技(北京)有限公司 一种含有叠氮功能基团的线性水凝胶的制备方法
EP4093862A1 (en) 2020-01-22 2022-11-30 Nuclera Nucleics Ltd Methods of nucleic acid synthesis
US12110541B2 (en) 2020-02-03 2024-10-08 10X Genomics, Inc. Methods for preparing high-resolution spatial arrays
US12112833B2 (en) 2020-02-04 2024-10-08 10X Genomics, Inc. Systems and methods for index hopping filtering
CN111171229B (zh) * 2020-02-12 2021-12-28 赛纳生物科技(北京)有限公司 一种核酸固载微球的制备方法
US12421558B2 (en) 2020-02-13 2025-09-23 10X Genomics, Inc. Systems and methods for joint interactive visualization of gene expression and DNA chromatin accessibility
US12281357B1 (en) 2020-02-14 2025-04-22 10X Genomics, Inc. In situ spatial barcoding
US11188778B1 (en) 2020-05-05 2021-11-30 Illumina, Inc. Equalization-based image processing and spatial crosstalk attenuator
CN115916967A (zh) 2020-05-12 2023-04-04 伊鲁米纳公司 使用重组末端脱氧核苷酸转移酶生成具有经修饰的碱基的核酸
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
AU2021295081A1 (en) 2020-06-22 2022-12-08 Illumina Cambridge Limited Nucleosides and nucleotides with 3' acetal blocking group
US12168801B1 (en) 2020-07-02 2024-12-17 10X Genomics, Inc. Hybrid/capture probe designs for full-length cDNA
US11981964B2 (en) 2020-07-28 2024-05-14 Illumina Cambridge Limited Substituted coumarin dyes and uses as fluorescent labels
MX2023000872A (es) 2020-08-06 2023-02-22 Illumina Inc Preparacion de genotecas de secuenciacion de arn y adn usando transposomas enlazados por globulos.
CA3182551A1 (en) * 2020-10-20 2022-04-28 Raymond Campos Flow cells
US20220195517A1 (en) 2020-12-17 2022-06-23 Illumina Cambridge Limited Long stokes shift chromenoquinoline dyes and uses in sequencing applications
US20220195196A1 (en) 2020-12-17 2022-06-23 Illumina Cambridge Limited Alkylpyridinium coumarin dyes and uses in sequencing applications
US20220195516A1 (en) 2020-12-17 2022-06-23 Illumina Cambridge Limited Methods, systems and compositions for nucleic acid sequencing
US20220195518A1 (en) 2020-12-22 2022-06-23 Illumina Cambridge Limited Methods and compositions for nucleic acid sequencing
WO2022144626A1 (en) 2020-12-31 2022-07-07 3M Innovative Properties Company Nanopatterned films with patterned surface chemistry
CA3199918A1 (en) 2021-01-05 2022-07-14 Randall Smith Compositions including functional groups coupled to substrates, and methods of making the same
CA3206511A1 (en) 2021-01-29 2022-08-04 Yir-Shyuan WU Methods, compositions and kits to improve seeding efficiency of flow cells with polynucleotides
KR20230157348A (ko) * 2021-03-09 2023-11-16 일루미나, 인코포레이티드 중합체, 중합체의 제조 방법, 및 올리고뉴클레오티드를 중합체에 커플링하는 방법
CN117222747A (zh) 2021-03-22 2023-12-12 伊鲁米纳剑桥有限公司 用于改善核酸簇克隆性的方法
MX2023011749A (es) * 2021-04-30 2024-01-12 Illumina Cambridge Ltd Celda de flujo y metodos.
JP2024516191A (ja) 2021-05-05 2024-04-12 イルミナ ケンブリッジ リミテッド ビス－ホウ素縮合複素環を含有する蛍光色素及び配列決定における使用
AU2022277632A1 (en) 2021-05-20 2023-11-09 Illumina Cambridge Limited Compositions and methods for sequencing by synthesis
CN117677435A (zh) 2021-06-15 2024-03-08 伊鲁米纳公司 用于测序的不含水凝胶的表面官能化
US20220414853A1 (en) 2021-06-25 2022-12-29 Illumina, Inc. Fiducials for use in registration of a patterned surface
CA3224034A1 (en) 2021-06-25 2022-12-29 Helge Nareid Linear fourier fiducial
EP4374343A1 (en) 2021-07-19 2024-05-29 Illumina, Inc. Intensity extraction with interpolation and adaptation for base calling
US11455487B1 (en) 2021-10-26 2022-09-27 Illumina Software, Inc. Intensity extraction and crosstalk attenuation using interpolation and adaptation for base calling
CN113265232B (zh) * 2021-07-21 2021-09-28 山东诺尔生物科技有限公司 一种包被剂用原料组合物、包被剂及其制备方法和用途
CN117813391A (zh) 2021-07-23 2024-04-02 因美纳有限公司 制备用于dna测序的基底表面的方法
WO2023034076A1 (en) 2021-08-31 2023-03-09 Illumina, Inc. Flow cell with enhanced well imaging resolution
WO2023044071A1 (en) 2021-09-17 2023-03-23 10X Genomics, Inc. Systems and methods for image registration or alignment
WO2023056328A2 (en) 2021-09-30 2023-04-06 Illumina, Inc. Solid supports and methods for depleting and/or enriching library fragments prepared from biosamples
US20230140008A1 (en) 2021-10-06 2023-05-04 10X Genomics, Inc. Systems and methods for evaluating biological samples
EP4419705A1 (en) 2021-10-20 2024-08-28 Illumina, Inc. Methods for capturing library dna for sequencing
US20230167495A1 (en) 2021-11-30 2023-06-01 10X Genomics, Inc. Systems and methods for identifying regions of aneuploidy in a tissue
WO2023114896A1 (en) 2021-12-16 2023-06-22 Illumina Cambridge Limited Methods for metal directed cleavage of surface-bound polynucleotides
WO2023111727A1 (en) 2021-12-17 2023-06-22 3M Innovative Properties Company Articles with photoiniferter attached to inorganic oxide surface and polymers prepared therefrom
CN117813399A (zh) 2021-12-20 2024-04-02 因美纳有限公司 用于化学裂解表面结合的多核苷酸的高碘酸盐组合物和方法
US20240401127A1 (en) 2021-12-20 2024-12-05 Illumina, Inc. Periodate compositions and methods for chemical cleavage of surface-bound polynucleotides
CN114316132B (zh) * 2022-01-28 2023-08-01 赛纳生物科技(北京)有限公司 一种乳液聚合合成功能性聚合物微球的方法
EP4479933A1 (en) 2022-02-15 2024-12-25 10x Genomics, Inc. Systems and methods for spatial analysis of analytes using fiducial alignment
AU2023240337A1 (en) 2022-03-22 2024-01-18 Illumina, Inc. Substrate with orthogonally functional nanodomains
WO2023186815A1 (en) 2022-03-28 2023-10-05 Illumina Cambridge Limited Labeled avidin and methods for sequencing
US20230313292A1 (en) 2022-03-29 2023-10-05 Illumina Cambridge Limited Chromenoquinoline dyes and uses in sequencing
AU2023246691A1 (en) 2022-03-30 2024-01-18 Illumina, Inc. Methods for chemical cleavage of surface-bound polynucleotides
US20230357845A1 (en) 2022-03-31 2023-11-09 Illumina, Inc. Compositions and methods for improving sequencing signals
CA3222797A1 (en) 2022-03-31 2023-10-05 Ramesh NEELAKANDAN Nucleosides and nucleotides with 3' vinyl blocking group
US20250272996A1 (en) 2022-04-26 2025-08-28 10X Genomics, Inc. Systems and methods for evaluating biological samples
WO2023232829A1 (en) 2022-05-31 2023-12-07 Illumina, Inc Compositions and methods for nucleic acid sequencing
CN115010852B (zh) * 2022-06-01 2023-10-10 郑州玛特瑞斯生物科技有限公司 一种测序芯片表面修饰用聚合物、测序芯片及其表面修饰方法
EP4547675A1 (en) 2022-06-28 2025-05-07 Illumina, Inc. Fluorescent dyes containing fused tetracyclic bis-boron heterocycle and uses in sequencing
US20240033738A1 (en) 2022-07-27 2024-02-01 Illumina, Inc. Flow cell based motion system calibration and control methods
WO2024031068A1 (en) 2022-08-05 2024-02-08 10X Genomics, Inc. Systems and methods for immunofluorescence quantification
WO2024036191A1 (en) 2022-08-10 2024-02-15 10X Genomics, Inc. Systems and methods for colocalization
WO2024039516A1 (en) 2022-08-19 2024-02-22 Illumina, Inc. Third dna base pair site-specific dna detection
US20240117426A1 (en) 2022-09-19 2024-04-11 Illumina, Inc. Nanogel particles having dual functionality and temperature responsiveness for particle clustering in nucleic acid sequencing systems
EP4594012A1 (en) 2022-09-26 2025-08-06 Illumina, Inc. Flow cell based motion system calibration and control methods
WO2024068889A2 (en) 2022-09-30 2024-04-04 Illumina, Inc. Compositions and methods for reducing photo damage during sequencing
KR20250111024A (ko) 2022-11-21 2025-07-22 일루미나, 인코포레이티드 가역적으로 가교결합된 하이드로겔 및 이를 클러스터 증폭에 사용하는 방법
WO2024123748A1 (en) 2022-12-07 2024-06-13 Illumina, Inc. Etch-free photoresist patterning in multi-depth nanowells
WO2024123866A1 (en) 2022-12-09 2024-06-13 Illumina, Inc. Nucleosides and nucleotides with 3´ blocking groups and cleavable linkers
CN120457203A (zh) * 2022-12-21 2025-08-08 博德研究所 单核高分辨率多模式空间基因组学
WO2024137774A1 (en) 2022-12-22 2024-06-27 Illumina, Inc. Palladium catalyst compositions and methods for sequencing by synthesis
CN119095983A (zh) 2022-12-22 2024-12-06 伊路米纳有限公司 用于边合成边测序的过渡金属催化剂组合物和方法
US20240271206A1 (en) 2022-12-27 2024-08-15 Illumina, Inc. Methods of sequencing using 3' allyl blocked nucleotides
WO2024158538A1 (en) 2023-01-27 2024-08-02 Illumina, Inc. Jitter correction image analysis
AU2024247164A1 (en) 2023-03-29 2024-12-12 Illumina, Inc. Naphthalimide dyes and uses in nucleic acid sequencing
US20240327909A1 (en) 2023-03-30 2024-10-03 Illumina, Inc. Compositions and methods for nucleic acid sequencing
WO2024238625A1 (en) 2023-05-15 2024-11-21 10X Genomics, Inc. Spatial antibody data normalization
WO2024249200A1 (en) 2023-05-26 2024-12-05 Illumina, Inc. Methods for preserving methylation status during clustering
WO2024254367A1 (en) 2023-06-09 2024-12-12 Illumina, Inc Method for polishing a substrate
WO2024261308A1 (en) 2023-06-23 2024-12-26 Susos Ag Low temperature reactive aryl azides
US20250010291A1 (en) 2023-06-28 2025-01-09 Illumina, Inc. Photoresist patterning in multi-depth nanowells
CN117087265A (zh) * 2023-08-12 2023-11-21 江苏中基新能源科技集团有限公司 高阻隔冷成型药用铝膜用铝箔
US20250075269A1 (en) 2023-08-31 2025-03-06 Illumina, Inc. Compositions and methods for nucleic acid sequencing
WO2025072484A1 (en) 2023-09-28 2025-04-03 Illumina, Inc. On-sequencer imaging flowcell reuse
US20250137048A1 (en) 2023-10-26 2025-05-01 Illumina, Inc. 4,5-substituted naphthalimide dyes and uses in nucleic acid sequencing
CN117486500A (zh) * 2023-11-03 2024-02-02 郑州玛特瑞斯生物科技有限公司 一种玻片量产工艺、玻片加工用装置
US20250163505A1 (en) 2023-11-17 2025-05-22 Illumina, Inc. Conjugated polymers or polymer dots as fluorescent labels
WO2025136890A1 (en) 2023-12-18 2025-06-26 Illumina, Inc. Hydrogel nanoparticles as labeling scaffold in sequencing
US20250215493A1 (en) 2023-12-28 2025-07-03 Illumina, Inc. Nucleotides with enzymatically cleavable 3'-o-glycoside blocking groups for sequencing
US20250215494A1 (en) 2023-12-29 2025-07-03 Illumina, Inc. Tricyclic polymethine dyes for nucleic acid sequencing
WO2025184226A1 (en) 2024-02-28 2025-09-04 Illumina, Inc. Nucleotides with terminal phosphate capping
WO2025188906A1 (en) 2024-03-08 2025-09-12 Illumina, Inc. Modified adenosine nucleotides

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010014448A1 (en) * 1997-09-30 2001-08-16 Surmodics, Inc. Target molecule attachment to surfaces

Family Cites Families (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54135525A (en) * 1978-04-12 1979-10-20 Konishiroku Photo Ind Co Ltd Photosensitive material
DE3706890A1 (de) 1987-03-04 1988-09-15 Bayer Ag Optisch aktive (meth)acrylamide, verfahren zu ihrer herstellung und ihre verwendung zur racematspaltung
GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
JPH0237350A (ja) * 1988-07-28 1990-02-07 Nippon Kayaku Co Ltd 感光性樹脂組成物
GB8822228D0 (en) 1988-09-21 1988-10-26 Southern E M Support-bound oligonucleotides
US5212253A (en) 1989-04-18 1993-05-18 Eastman Kodak Company Electrophoresis element comprising a polymer containing a haloacetamido group
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
DE3924454A1 (de) 1989-07-24 1991-02-07 Cornelis P Prof Dr Hollenberg Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips)
US5302509A (en) 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
WO1991006678A1 (en) 1989-10-26 1991-05-16 Sri International Dna sequencing
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
ATE148889T1 (de) 1991-09-18 1997-02-15 Affymax Tech Nv Verfahren zur synthese der verschiedenen sammlungen von oligomeren
ATE241426T1 (de) 1991-11-22 2003-06-15 Affymetrix Inc A Delaware Corp Verfahren zur herstellung von polymerarrays
ATE278807T1 (de) 1992-02-19 2004-10-15 New York Health Res Inst Neue anordnungen von oligonukleotiden und ihr nutzen zum sortieren, isolieren, sequenzierung und manipulieren von nukleinsäuren
US5583211A (en) 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US5472672A (en) 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
EP0730663B1 (en) 1993-10-26 2003-09-24 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
US5429807A (en) 1993-10-28 1995-07-04 Beckman Instruments, Inc. Method and apparatus for creating biopolymer arrays on a solid support surface
CA2185239C (en) 1994-03-16 2002-12-17 Nanibhushan Dattagupta Isothermal strand displacement nucleic acid amplification
US5552278A (en) 1994-04-04 1996-09-03 Spectragen, Inc. DNA sequencing by stepwise ligation and cleavage
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5641658A (en) 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
US5604097A (en) 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
US5624711A (en) 1995-04-27 1997-04-29 Affymax Technologies, N.V. Derivatization of solid supports and methods for oligomer synthesis
US5783502A (en) * 1995-06-07 1998-07-21 Bsi Corporation Virus inactivating coatings
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
WO1997004131A1 (en) 1995-07-21 1997-02-06 Forsyth Dental Infirmary For Children Single primer amplification of polynucleotide hairpins
ATE496288T1 (de) 1995-10-11 2011-02-15 Luminex Corp Gleichzeitige mehrfachanalyse klinischer proben
US5658734A (en) 1995-10-17 1997-08-19 International Business Machines Corporation Process for synthesizing chemical compounds
US6458530B1 (en) 1996-04-04 2002-10-01 Affymetrix Inc. Selecting tag nucleic acids
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
JP2001509828A (ja) 1997-01-08 2001-07-24 プロリゴ・エルエルシー 高分子のバイオコンジュゲーション
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
AU6846798A (en) 1997-04-01 1998-10-22 Glaxo Group Limited Method of nucleic acid sequencing
ATE545710T1 (de) 1997-04-01 2012-03-15 Illumina Cambridge Ltd Verfahren zur vervielfältigung von nukleinsäuren
US5948621A (en) 1997-09-30 1999-09-07 The United States Of America As Represented By The Secretary Of The Navy Direct molecular patterning using a micro-stamp gel
US5858653A (en) 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
US6485944B1 (en) 1997-10-10 2002-11-26 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6511803B1 (en) 1997-10-10 2003-01-28 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6087102A (en) 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
US7427678B2 (en) 1998-01-08 2008-09-23 Sigma-Aldrich Co. Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method
US6287776B1 (en) 1998-02-02 2001-09-11 Signature Bioscience, Inc. Method for detecting and classifying nucleic acid hybridization
JP3944996B2 (ja) 1998-03-05 2007-07-18 株式会社日立製作所 Ｄｎａプローブアレー
AU4218499A (en) 1998-05-27 1999-12-13 Syntrix Biochip Light-mediated method and apparatus for the regional analysis of biologic material
US6031078A (en) 1998-06-16 2000-02-29 Millennium Pharmaceuticals, Inc. MTbx protein and nucleic acid molecules and uses therefor
IL141148A0 (en) 1998-07-30 2002-02-10 Solexa Ltd Arrayed biomolecules and their use in sequencing
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6277628B1 (en) 1998-10-02 2001-08-21 Incyte Genomics, Inc. Linear microarrays
US6391937B1 (en) 1998-11-25 2002-05-21 Motorola, Inc. Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers
US6699693B1 (en) 1999-02-04 2004-03-02 Sloan-Kettering Institute For Cancer Research Process for DNA replication
WO2000046408A1 (en) 1999-02-04 2000-08-10 Sloan-Kettering Institute For Cancer Research Process for dna replication
ATE553219T1 (de) 1999-04-20 2012-04-15 Illumina Inc Erkennung von nukleinsäurereaktionen auf bead- arrays
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US6355431B1 (en) 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
US20050181440A1 (en) 1999-04-20 2005-08-18 Illumina, Inc. Nucleic acid sequencing using microsphere arrays
US6221635B1 (en) 1999-05-06 2001-04-24 The Wistar Institute Methods for solid-phase amplification of DNA template (SPADT) using multiarrays
US6664061B2 (en) 1999-06-25 2003-12-16 Amersham Biosciences Ab Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
US6372813B1 (en) 1999-06-25 2002-04-16 Motorola Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays
US7244559B2 (en) 1999-09-16 2007-07-17 454 Life Sciences Corporation Method of sequencing a nucleic acid
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
EP1221050A2 (en) 1999-09-30 2002-07-10 Nanogen, Inc. Biomolecular attachment sites on microelectronic arrays
US6077674A (en) 1999-10-27 2000-06-20 Agilent Technologies Inc. Method of producing oligonucleotide arrays with features of high purity
DK1259643T3 (da) 2000-02-07 2009-02-23 Illumina Inc Fremgangsmåde til detektion af nukleinsyre ved anvendelse af universel priming
US6913884B2 (en) 2001-08-16 2005-07-05 Illumina, Inc. Compositions and methods for repetitive use of genomic DNA
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
AU2001241723A1 (en) 2000-02-25 2001-09-03 Affymetrix, Inc. Methods for multi-stage solid phase amplification of nucleic acids
US6410643B1 (en) 2000-03-09 2002-06-25 Surmodics, Inc. Solid phase synthesis method and reagent
CN100462433C (zh) 2000-07-07 2009-02-18 维西根生物技术公司 实时序列测定
AU2001279244A1 (en) 2000-08-09 2002-02-18 Motorola, Inc. The use and evaluation of a (2+2) photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
EP1328810B1 (en) 2000-10-26 2009-01-21 Biocept, Inc. Three dimensional format biochip
WO2002044425A2 (en) 2000-12-01 2002-06-06 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
FR2817968B1 (fr) 2000-12-07 2003-03-21 Bio Merieux Dispositif de capture d'une molecule cible
AR031640A1 (es) 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
EP2465943A3 (en) 2001-03-16 2012-10-03 Kalim Mir Linear polymer display
CA2444649C (en) 2001-04-20 2012-10-02 The Penn State Research Foundation Methods for nucleic acid manipulation
JP2005514617A (ja) 2001-07-02 2005-05-19 ザ、ボード、オブ、トラスティーズ、オブ、ザ、リーランド、スタンフォード、ジュニア、ユニバーシティ 細胞の表現型決定および操作のためのマイクロアレイ
US6989267B2 (en) 2001-07-02 2006-01-24 Agilent Technologies, Inc. Methods of making microarrays with substrate surfaces having covalently bound polyelectrolyte films
JPWO2003014394A1 (ja) 2001-08-03 2004-11-25 旭メディカル株式会社 生体適合性評価法
US20030157260A1 (en) 2001-10-25 2003-08-21 Rubner Michael F. Polyelectrolyte multilayers that influence cell growth, methods of applying them, and articles coated with them
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
EP1483404A2 (en) 2002-03-05 2004-12-08 Solexa Ltd. Methods for detecting genome-wide sequence variations associated with a phenotype
US20040002090A1 (en) 2002-03-05 2004-01-01 Pascal Mayer Methods for detecting genome-wide sequence variations associated with a phenotype
KR101048279B1 (ko) 2002-05-30 2011-07-13 더 스크립스 리서치 인스티튜트 구리 촉매 작용하에서의 아지드와 아세틸렌과의 리게이션
WO2004002618A1 (en) 2002-06-27 2004-01-08 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
ES2550513T3 (es) 2002-08-23 2015-11-10 Illumina Cambridge Limited Nucleótidos modificados para secuenciación de polinucleótidos
US7595883B1 (en) 2002-09-16 2009-09-29 The Board Of Trustees Of The Leland Stanford Junior University Biological analysis arrangement and approach therefor
DE602004026033D1 (de) 2003-01-29 2010-04-29 454 Corp Zweiendige sequenzierung
CA2514471C (en) 2003-02-19 2013-09-10 Mcmaster University Composite materials comprising supported porous gels
AU2004253882B2 (en) 2003-06-20 2010-06-10 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
CA2531105C (en) 2003-07-05 2015-03-17 The Johns Hopkins University Method and compositions for detection and enumeration of genetic variations
US7309593B2 (en) * 2003-10-01 2007-12-18 Surmodics, Inc. Attachment of molecules to surfaces
GB0326073D0 (en) 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
EP3175914A1 (en) 2004-01-07 2017-06-07 Illumina Cambridge Limited Improvements in or relating to molecular arrays
AU2005272823B2 (en) * 2004-08-13 2012-04-12 President And Fellows Of Harvard College An ultra high-throughput opti-nanopore DNA readout platform
US7302146B2 (en) 2004-09-17 2007-11-27 Pacific Biosciences Of California, Inc. Apparatus and method for analysis of molecules
EP2620510B2 (en) * 2005-06-15 2020-02-19 Complete Genomics Inc. Single molecule arrays for genetic and chemical analysis
EP2385140B1 (en) 2005-07-25 2014-07-16 Alere San Diego, Inc. Methods for multiplexing recombinase polymerase amplification
US7405281B2 (en) 2005-09-29 2008-07-29 Pacific Biosciences Of California, Inc. Fluorescent nucleotide analogs and uses therefor
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
WO2007107710A1 (en) 2006-03-17 2007-09-27 Solexa Limited Isothermal methods for creating clonal single molecule arrays
EP3722409A1 (en) 2006-03-31 2020-10-14 Illumina, Inc. Systems and devices for sequence by synthesis analysis
CA2650993C (en) 2006-05-04 2015-06-16 Asm Scientific, Inc. Recombinase polymerase amplification
AU2007309504B2 (en) 2006-10-23 2012-09-13 Pacific Biosciences Of California, Inc. Polymerase enzymes and reagents for enhanced nucleic acid sequencing
US8262900B2 (en) 2006-12-14 2012-09-11 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
CA2672315A1 (en) 2006-12-14 2008-06-26 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes using large scale fet arrays
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
CN101848757B (zh) 2007-07-13 2013-12-04 里兰斯坦福初级大学理事会 用于改进的生物测定法的使用电场的方法和设备
WO2009073702A1 (en) * 2007-12-04 2009-06-11 E. I. Du Pont De Nemours And Company Decarboxylating block copolymers
WO2009099126A1 (ja) * 2008-02-07 2009-08-13 Riken 光反応性共重合体、表面改質剤、親水化処理剤、吸着抑制剤、物質固定化剤、表面改質方法、親水化方法、吸着抑制方法および物質固定化方法
CN101514956B (zh) * 2008-08-18 2011-06-22 北京九州泰康生物科技有限责任公司 一类分子检测系统
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US9309557B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Nucleic acid amplification
CN102741369B (zh) * 2010-01-11 2015-05-06 利伯海尔豪斯格雷特奥森豪森有限公司 具有抗冰性质的表面涂层
GB2482122B (en) 2010-07-19 2014-02-19 Intellectual Ventures Holding 81 Llc Communication unit and pilot method for time varying channels
WO2012058096A1 (en) 2010-10-27 2012-05-03 Illumina, Inc. Microdevices and biosensor cartridges for biological or chemical analysis and systems and methods for the same
US8951781B2 (en) 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
WO2012106072A2 (en) 2011-02-03 2012-08-09 Illumina, Inc. Methods for minimizing sequence specific bias
JP5818245B2 (ja) * 2011-03-25 2015-11-18 国立研究開発法人物質・材料研究機構 アジド基又はアルキン基を有するイソプロピルアクリルアミド誘導体およびその重合体
EP2718465B1 (en) 2011-06-09 2022-04-13 Illumina, Inc. Method of making an analyte array
CA2856163C (en) 2011-10-28 2019-05-07 Illumina, Inc. Microarray fabrication system and method
US9012022B2 (en) * 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
US8895249B2 (en) 2012-06-15 2014-11-25 Illumina, Inc. Kinetic exclusion amplification of nucleic acid libraries

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010014448A1 (en) * 1997-09-30 2001-08-16 Surmodics, Inc. Target molecule attachment to surfaces

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