AU2012315384B2 - Treating pancreatic cancer and non-small cell lung cancer with ATR inhibitors - Google Patents
Treating pancreatic cancer and non-small cell lung cancer with ATR inhibitors Download PDFInfo
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- AU2012315384B2 AU2012315384B2 AU2012315384A AU2012315384A AU2012315384B2 AU 2012315384 B2 AU2012315384 B2 AU 2012315384B2 AU 2012315384 A AU2012315384 A AU 2012315384A AU 2012315384 A AU2012315384 A AU 2012315384A AU 2012315384 B2 AU2012315384 B2 AU 2012315384B2
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- gemcitabine
- pancreatic cancer
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| AU2019203240A AU2019203240B2 (en) | 2011-09-30 | 2019-05-09 | Treating pancreatic cancer and non-small cell lung cancer with ATR inhibitors |
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| PCT/US2012/058374 WO2013049859A1 (en) | 2011-09-30 | 2012-10-01 | Treating pancreatic cancer and non-small cell lung cancer with atr inhibitors |
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| AU2019203240A Ceased AU2019203240B2 (en) | 2011-09-30 | 2019-05-09 | Treating pancreatic cancer and non-small cell lung cancer with ATR inhibitors |
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| WO2013071090A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
| EP2776429A1 (en) * | 2011-11-09 | 2014-09-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
| NZ726671A (en) | 2012-04-05 | 2018-04-27 | Vertex Pharma | Compounds useful as inhibitors of atr kinase and combination therapies thereof |
| CN103373996A (zh) | 2012-04-20 | 2013-10-30 | 山东亨利医药科技有限责任公司 | 作为crth2受体拮抗剂的二并环衍生物 |
| DK2904406T3 (en) | 2012-10-04 | 2018-06-18 | Vertex Pharma | METHOD OF DETERMINING THE ATR INHIBITION, INCREASED DNA DAMAGE |
| US8912198B2 (en) | 2012-10-16 | 2014-12-16 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
| CN104903325B (zh) | 2012-12-07 | 2017-10-20 | 沃泰克斯药物股份有限公司 | 可用作atr激酶抑制剂的化合物 |
| JP6096005B2 (ja) | 2013-02-26 | 2017-03-15 | リンテック株式会社 | シート剥離装置および剥離方法 |
| SI3077397T1 (sl) | 2013-12-06 | 2020-02-28 | Vertex Pharmaceuticals Inc. | 2-amino-6-fluoro-N-(5-fluoro-piridin-3-IL)pirazolo(1,5-A)pirimidin-3- karboksamidna spojina, koristna kot inhibitor kinaze ATR, njena priprava, različne trdne oblike in njeni radioaktivno označeni derivati |
| AU2015271030B2 (en) | 2014-06-05 | 2019-05-16 | Vertex Pharmaceuticals Incorporated | Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo [1,5-a] pyrimidin-3-carboxamide compound useful as ATR kinase inhibitor, the preparation of said compound and different solid forms thereof |
| RU2736219C2 (ru) | 2014-06-17 | 2020-11-12 | Вертекс Фармасьютикалз Инкорпорейтед | Способ лечения рака с использованием комбинации ингибиторов снк1 и atr |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010071837A1 (en) * | 2008-12-19 | 2010-06-24 | Vertex Pharmaceuticals Incorporated | Pyrazine derivatives useful as inhibitors of atr kinase |
Non-Patent Citations (1)
| Title |
|---|
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