ATE523508T1 - Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate - Google Patents

Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate

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Publication number
ATE523508T1
ATE523508T1 AT08841876T AT08841876T ATE523508T1 AT E523508 T1 ATE523508 T1 AT E523508T1 AT 08841876 T AT08841876 T AT 08841876T AT 08841876 T AT08841876 T AT 08841876T AT E523508 T1 ATE523508 T1 AT E523508T1
Authority
AT
Austria
Prior art keywords
pyridine
treatment
cell proliferative
proliferative diseases
pyrazine derivatives
Prior art date
Application number
AT08841876T
Other languages
English (en)
Inventor
Bernard Barlaam
Justin Bower
Benedicte Delouvrie
Gary Fairley
Craig Harris
Christine Lambert
Gilles Ouvry
Jon Winter
Original Assignee
Astrazeneca Ab
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Publication date
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Publication of ATE523508T1 publication Critical patent/ATE523508T1/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT08841876T 2007-10-25 2008-10-22 Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate ATE523508T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07301491 2007-10-25
EP07305005 2007-12-21
EP08305180 2008-05-19
PCT/GB2008/050974 WO2009053737A2 (en) 2007-10-25 2008-10-22 Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders

Publications (1)

Publication Number Publication Date
ATE523508T1 true ATE523508T1 (de) 2011-09-15

Family

ID=40580139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08841876T ATE523508T1 (de) 2007-10-25 2008-10-22 Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate

Country Status (18)

Country Link
US (1) US8017611B2 (de)
EP (1) EP2215085B1 (de)
JP (1) JP2011500778A (de)
KR (1) KR20100089090A (de)
CN (1) CN101910158A (de)
AR (1) AR069078A1 (de)
AT (1) ATE523508T1 (de)
AU (1) AU2008315746A1 (de)
CA (1) CA2703653A1 (de)
CL (1) CL2008003188A1 (de)
CO (1) CO6270364A2 (de)
EC (1) ECSP10010197A (de)
IL (1) IL205108A0 (de)
MX (1) MX2010004491A (de)
PE (1) PE20091116A1 (de)
TW (1) TW200920367A (de)
UY (1) UY31430A1 (de)
WO (1) WO2009053737A2 (de)

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IL205108A0 (en) 2010-11-30
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