GB0619342D0 - New chemical compounds - Google Patents
New chemical compoundsInfo
- Publication number
- GB0619342D0 GB0619342D0 GBGB0619342.9A GB0619342A GB0619342D0 GB 0619342 D0 GB0619342 D0 GB 0619342D0 GB 0619342 A GB0619342 A GB 0619342A GB 0619342 D0 GB0619342 D0 GB 0619342D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical compounds
- new chemical
- new
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0619342.9A GB0619342D0 (en) | 2006-09-30 | 2006-09-30 | New chemical compounds |
PCT/GB2007/003687 WO2008038010A1 (en) | 2006-09-30 | 2007-09-28 | Pyrazine derivatives and their use in therapy |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0619342.9A GB0619342D0 (en) | 2006-09-30 | 2006-09-30 | New chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB0619342D0 true GB0619342D0 (en) | 2006-11-08 |
Family
ID=37435006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0619342.9A Ceased GB0619342D0 (en) | 2006-09-30 | 2006-09-30 | New chemical compounds |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0619342D0 (en) |
WO (1) | WO2008038010A1 (en) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0713259D0 (en) * | 2007-07-09 | 2007-08-15 | Astrazeneca Ab | Pyrazine derivatives 954 |
WO2009024825A1 (en) * | 2007-08-21 | 2009-02-26 | Astrazeneca Ab | 2-pyrazinylbenzimidazole derivatives as receptor tyrosine kinase inhibitors |
AU2008315746A1 (en) | 2007-10-25 | 2009-04-30 | Astrazeneca Ab | Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders |
NZ593316A (en) | 2008-11-10 | 2013-06-28 | Vertex Pharma | Pyrazine compounds useful as inhibitors of atr kinase |
LT3354650T (en) | 2008-12-19 | 2022-06-27 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
WO2011143419A1 (en) | 2010-05-12 | 2011-11-17 | Vertex Pharmaceuticals Incorporated | Pyrazines useful as inhibitors of atr kinase |
JP2013526538A (en) | 2010-05-12 | 2013-06-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | Compounds useful as ATR kinase inhibitors |
JP5856151B2 (en) | 2010-05-12 | 2016-02-09 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | 2-Aminopyridine derivatives useful as ATR kinase inhibitors |
WO2011143425A2 (en) | 2010-05-12 | 2011-11-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
US9062008B2 (en) | 2010-05-12 | 2015-06-23 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
WO2011143426A1 (en) | 2010-05-12 | 2011-11-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
WO2011163527A1 (en) | 2010-06-23 | 2011-12-29 | Vertex Pharmaceuticals Incorporated | Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase |
WO2012138938A1 (en) | 2011-04-05 | 2012-10-11 | Vertex Pharmaceuticals Incorporated | Aminopyrazine compounds useful as inhibitors of tra kinase |
JP2014517079A (en) | 2011-06-22 | 2014-07-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | Compounds useful as ATR kinase inhibitors |
JP2014522818A (en) | 2011-06-22 | 2014-09-08 | バーテックス ファーマシューティカルズ インコーポレイテッド | Compounds useful as ATR kinase inhibitors |
EP2723745A1 (en) | 2011-06-22 | 2014-04-30 | Vertex Pharmaceuticals Inc. | Compounds useful as inhibitors of atr kinase |
SG10201606774UA (en) | 2011-09-30 | 2016-10-28 | Vertex Pharma | Processes for making compounds useful as inhibitors of atr kinase |
BR112014007690B1 (en) | 2011-09-30 | 2022-10-04 | Vertex Pharmaceuticals Incorporated | Uses of ATR inhibitors in the treatment of pancreatic cancer and non-small cell lung cancer |
MX2014003796A (en) | 2011-09-30 | 2015-01-16 | Vertex Pharma | Compounds useful as inhibitors of atr kinase. |
WO2013049720A1 (en) | 2011-09-30 | 2013-04-04 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2751088B1 (en) | 2011-09-30 | 2016-04-13 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
US8846918B2 (en) | 2011-11-09 | 2014-09-30 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
EP2776422A1 (en) | 2011-11-09 | 2014-09-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
WO2013071093A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Pyrazine compounds useful as inhibitors of atr kinase |
WO2013071085A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Pyrazine compounds useful as inhibitors of atr kinase |
WO2013071088A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2833973B1 (en) | 2012-04-05 | 2017-09-13 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase and combination therapies thereof |
WO2014055756A1 (en) | 2012-10-04 | 2014-04-10 | Vertex Pharmaceuticals Incorporated | Method for measuring atr inhibition mediated increases in dna damage |
WO2014062604A1 (en) | 2012-10-16 | 2014-04-24 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
PL2941432T3 (en) | 2012-12-07 | 2018-09-28 | Vertex Pharmaceuticals Incorporated | 2-amino-6-fluoro-n-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5alpha]pyrimidine-3-carboxamide as inhibitor of atr kinase |
EP2970286A1 (en) | 2013-03-15 | 2016-01-20 | Vertex Pharmaceuticals Inc. | Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase |
WO2015085132A1 (en) | 2013-12-06 | 2015-06-11 | Vertex Pharmaceuticals Incorporated | 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, its preparation, different solid forms and radiolabelled derivatives thereof |
US9670215B2 (en) | 2014-06-05 | 2017-06-06 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
WO2015195740A1 (en) | 2014-06-17 | 2015-12-23 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of chk1 and atr inhibitors |
US11464774B2 (en) | 2015-09-30 | 2022-10-11 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors |
PL3762368T3 (en) | 2018-03-08 | 2022-06-06 | Incyte Corporation | Aminopyrazine diol compounds as pi3k-y inhibitors |
US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1463506T3 (en) * | 2001-12-24 | 2010-01-11 | Astrazeneca Ab | Substituted quinazoline derivatives as inhibitors of aurora kinases |
TW200505452A (en) * | 2003-06-17 | 2005-02-16 | Astrazeneca Ab | Chemical compounds |
TW200624431A (en) * | 2004-09-24 | 2006-07-16 | Hoffmann La Roche | Phthalazinone derivatives, their manufacture and use as pharmaceutical agents |
MX2007005155A (en) * | 2004-10-29 | 2007-06-26 | Banyu Pharma Co Ltd | Novel aminopyridine derivatives having aurora a selective inhibitory action. |
-
2006
- 2006-09-30 GB GBGB0619342.9A patent/GB0619342D0/en not_active Ceased
-
2007
- 2007-09-28 WO PCT/GB2007/003687 patent/WO2008038010A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2008038010A1 (en) | 2008-04-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB0619342D0 (en) | New chemical compounds | |
EP1984376A4 (en) | Chemical compounds | |
IL192661A0 (en) | Chemical compounds | |
IL196595A0 (en) | Chemical compounds | |
EP2136632A4 (en) | Chemical compounds | |
IL202625A0 (en) | New chemical compounds | |
GB0713117D0 (en) | Chemical compounds | |
EP2136635A4 (en) | Chemical compounds | |
GB0611507D0 (en) | Chemical compounds | |
GB0702413D0 (en) | New chemical compounds | |
GB0611506D0 (en) | Chemical compounds | |
GB0623388D0 (en) | Chemical compounds | |
GB0611552D0 (en) | Chemical compounds | |
GB0718432D0 (en) | New chemical compounds | |
GB0619343D0 (en) | New chemical compounds | |
GB0718433D0 (en) | New chemical compounds | |
ZA200903100B (en) | Chemical compounds | |
GB0625198D0 (en) | Chemical compounds | |
GB0718434D0 (en) | New chemical compounds | |
GB0601215D0 (en) | Chemical compounds | |
GB0623357D0 (en) | Chemical compounds | |
GB0615670D0 (en) | Chemical compounds | |
GB0614552D0 (en) | Chemical Compounds | |
GB0625371D0 (en) | Chemical compounds | |
GB0607550D0 (en) | New chemical compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |