ATE458469T3 - Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit - Google Patents

Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit Download PDF

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Publication number
ATE458469T3
ATE458469T3 AT05010806T AT05010806T ATE458469T3 AT E458469 T3 ATE458469 T3 AT E458469T3 AT 05010806 T AT05010806 T AT 05010806T AT 05010806 T AT05010806 T AT 05010806T AT E458469 T3 ATE458469 T3 AT E458469T3
Authority
AT
Austria
Prior art keywords
present
directed
patient
flowable composition
implant
Prior art date
Application number
AT05010806T
Other languages
English (en)
Inventor
Richard Dunn
John S Garrett
Harish Ravivarapu
Bhagya L Chandrashekar
Original Assignee
Qlt Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27099398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE458469(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qlt Usa Inc filed Critical Qlt Usa Inc
Publication of ATE458469T3 publication Critical patent/ATE458469T3/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mechanical Engineering (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AT05010806T 2000-09-21 2001-09-21 Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit ATE458469T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66617400A 2000-09-21 2000-09-21
US09/711,758 US6565874B1 (en) 1998-10-28 2000-11-13 Polymeric delivery formulations of leuprolide with improved efficacy

Publications (1)

Publication Number Publication Date
ATE458469T3 true ATE458469T3 (de) 2010-03-15

Family

ID=27099398

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05010806T ATE458469T3 (de) 2000-09-21 2001-09-21 Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit
AT01973341T ATE296088T3 (de) 2000-09-21 2001-09-21 Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01973341T ATE296088T3 (de) 2000-09-21 2001-09-21 Polymere verabreichungsform von leuprolid mit verbesserter wirksamkeit

Country Status (26)

Country Link
US (8) US6565874B1 (de)
EP (3) EP2158900B1 (de)
JP (4) JP2004510807A (de)
KR (1) KR100831113B1 (de)
CN (2) CN100536922C (de)
AT (2) ATE458469T3 (de)
AU (4) AU9293101A (de)
BR (1) BRPI0114069B8 (de)
CA (1) CA2436275C (de)
CY (3) CY1106045T1 (de)
CZ (1) CZ303134B6 (de)
DE (2) DE60141421D1 (de)
DK (3) DK2158900T3 (de)
ES (3) ES2241876T7 (de)
HU (1) HU228386B1 (de)
IL (2) IL155006A0 (de)
IS (1) IS6794A (de)
MX (1) MXPA03002552A (de)
NZ (1) NZ525210A (de)
PL (1) PL226346B1 (de)
PT (3) PT1322286E (de)
RU (1) RU2271826C2 (de)
SI (1) SI1322286T1 (de)
SK (1) SK287528B6 (de)
WO (1) WO2002030393A2 (de)
ZA (1) ZA200302944B (de)

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DK2158900T3 (da) 2013-02-18
AU2006241376B2 (en) 2010-02-04
CY1113920T1 (el) 2016-07-27
US20150150937A1 (en) 2015-06-04
PL361671A1 (en) 2004-10-04
AU2010201645A1 (en) 2010-05-20
CN101669900A (zh) 2010-03-17
CA2436275C (en) 2007-01-02
CN100536922C (zh) 2009-09-09
EP1322286B1 (de) 2005-05-25
CN101669900B (zh) 2013-07-24
DK1586309T6 (da) 2019-10-07
DE60111068T2 (de) 2006-01-26
US9254307B2 (en) 2016-02-09
ES2241876T3 (es) 2005-11-01
PT1322286E (pt) 2005-08-31
CN1474685A (zh) 2004-02-11
DE60111068D1 (de) 2005-06-30
PT1586309E (pt) 2010-05-28
US20030133964A1 (en) 2003-07-17
DE60111068T3 (de) 2018-01-04
SI1322286T1 (en) 2005-10-31
DK1586309T3 (da) 2010-06-14
US20070104759A1 (en) 2007-05-10
ATE296088T3 (de) 2005-06-15
AU2006241376A1 (en) 2006-12-14
ZA200302944B (en) 2004-08-24
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JP5969190B2 (ja) 2016-08-17
JP2014240439A (ja) 2014-12-25
DE60141421D1 (de) 2010-04-08
JP2013253101A (ja) 2013-12-19
US6773714B2 (en) 2004-08-10
IS6794A (is) 2003-04-23
DK1322286T3 (da) 2005-08-01
EP1322286B3 (de) 2017-08-16
ES2341777T3 (es) 2010-06-28
JP6087886B2 (ja) 2017-03-01
HK1141459A1 (en) 2010-11-12
AU2010201645B2 (en) 2012-07-12
WO2002030393A2 (en) 2002-04-18
JP6061823B2 (ja) 2017-01-18
RU2271826C2 (ru) 2006-03-20
EP1586309B3 (de) 2019-09-18
US20100226954A1 (en) 2010-09-09
EP1586309B1 (de) 2010-02-24
US20160106805A1 (en) 2016-04-21
JP2012012418A (ja) 2012-01-19
PT2158900E (pt) 2013-03-11
HUP0302981A2 (hu) 2004-01-28
NZ525210A (en) 2004-10-29
US8486455B2 (en) 2013-07-16
EP2158900A1 (de) 2010-03-03
BRPI0114069B8 (pt) 2021-05-25
CA2436275A1 (en) 2002-04-18
EP2158900B1 (de) 2013-01-23
CZ20031124A3 (cs) 2003-12-17
KR20030064401A (ko) 2003-07-31
CY1110653T1 (el) 2015-06-10
CY1106045T1 (el) 2011-04-06
EP1322286A2 (de) 2003-07-02
IL155006A (en) 2007-06-03

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