DK1322286T3 - Polymere afgivelsesformuleringer af leuprolid med forbedret virkningsfuldhed - Google Patents

Polymere afgivelsesformuleringer af leuprolid med forbedret virkningsfuldhed

Info

Publication number
DK1322286T3
DK1322286T3 DK01973341T DK01973341T DK1322286T3 DK 1322286 T3 DK1322286 T3 DK 1322286T3 DK 01973341 T DK01973341 T DK 01973341T DK 01973341 T DK01973341 T DK 01973341T DK 1322286 T3 DK1322286 T3 DK 1322286T3
Authority
DK
Denmark
Prior art keywords
present
directed
patient
flowable composition
implant
Prior art date
Application number
DK01973341T
Other languages
English (en)
Other versions
DK1322286T6 (da
Inventor
Richard L Dunn
Harish Ravivarapu
Bhagya L Chandrashekar
John S Garrett
Original Assignee
Atrix Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27099398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1322286(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Atrix Lab Inc filed Critical Atrix Lab Inc
Application granted granted Critical
Publication of DK1322286T3 publication Critical patent/DK1322286T3/da
Publication of DK1322286T6 publication Critical patent/DK1322286T6/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
DK01973341.9T 2000-09-21 2001-09-21 Polymere afgivelsesformuleringer af leuprolid med forbedret virkningsfuldhed DK1322286T6 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66617400A 2000-09-21 2000-09-21
US09/711,758 US6565874B1 (en) 1998-10-28 2000-11-13 Polymeric delivery formulations of leuprolide with improved efficacy
PCT/US2001/029612 WO2002030393A2 (en) 2000-09-21 2001-09-21 Polymeric delivery formulations of leuprolide with improved efficacy
EP01973341.9A EP1322286B3 (en) 2000-09-21 2001-09-21 Polymeric delivery formulations of leuprolide with improved efficacy

Publications (2)

Publication Number Publication Date
DK1322286T3 true DK1322286T3 (da) 2005-08-01
DK1322286T6 DK1322286T6 (da) 2017-11-13

Family

ID=27099398

Family Applications (3)

Application Number Title Priority Date Filing Date
DK09012462.9T DK2158900T3 (da) 2000-09-21 2001-09-21 Polymere indgivelsesformuleringer af leuprolid med forbedret virkning
DK01973341.9T DK1322286T6 (da) 2000-09-21 2001-09-21 Polymere afgivelsesformuleringer af leuprolid med forbedret virkningsfuldhed
DK05010806.7T DK1586309T6 (da) 2000-09-21 2001-09-21 Polymere indgivelsesformuleringer af leuprolid med forbedret virkning

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK09012462.9T DK2158900T3 (da) 2000-09-21 2001-09-21 Polymere indgivelsesformuleringer af leuprolid med forbedret virkning

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK05010806.7T DK1586309T6 (da) 2000-09-21 2001-09-21 Polymere indgivelsesformuleringer af leuprolid med forbedret virkning

Country Status (27)

Country Link
US (8) US6565874B1 (da)
EP (3) EP1322286B3 (da)
JP (4) JP2004510807A (da)
KR (1) KR100831113B1 (da)
CN (2) CN101669900B (da)
AT (2) ATE458469T3 (da)
AU (4) AU2001292931B2 (da)
BR (1) BRPI0114069B8 (da)
CA (1) CA2436275C (da)
CY (3) CY1106045T1 (da)
CZ (1) CZ303134B6 (da)
DE (2) DE60111068T3 (da)
DK (3) DK2158900T3 (da)
ES (3) ES2341777T7 (da)
HK (2) HK1139596A1 (da)
HU (1) HU228386B1 (da)
IL (2) IL155006A0 (da)
IS (1) IS6794A (da)
MX (1) MXPA03002552A (da)
NZ (1) NZ525210A (da)
PL (1) PL226346B1 (da)
PT (3) PT1586309E (da)
RU (1) RU2271826C2 (da)
SI (1) SI1322286T1 (da)
SK (1) SK287528B6 (da)
WO (1) WO2002030393A2 (da)
ZA (1) ZA200302944B (da)

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ES2341777T7 (es) 2020-05-08
AU2006241376A1 (en) 2006-12-14
JP2012012418A (ja) 2012-01-19
CN101669900B (zh) 2013-07-24
EP2158900A1 (en) 2010-03-03
WO2002030393A2 (en) 2002-04-18
US6773714B2 (en) 2004-08-10
PT1586309E (pt) 2010-05-28
US8486455B2 (en) 2013-07-16
AU9293101A (en) 2002-04-22
EP1586309B1 (en) 2010-02-24
DE60111068D1 (de) 2005-06-30
DK2158900T3 (da) 2013-02-18
ATE296088T3 (de) 2005-06-15
US20150150937A1 (en) 2015-06-04
EP1322286A2 (en) 2003-07-02
CY1106045T1 (el) 2011-04-06
BR0114069A (pt) 2004-02-10
HUP0302981A2 (hu) 2004-01-28
BRPI0114069B1 (pt) 2016-08-23
SK5152003A3 (en) 2003-10-07
AU2010201645A1 (en) 2010-05-20
JP2014240439A (ja) 2014-12-25
BRPI0114069B8 (pt) 2021-05-25
WO2002030393A3 (en) 2002-06-27
US20100226954A1 (en) 2010-09-09
ZA200302944B (en) 2004-08-24
CZ20031124A3 (cs) 2003-12-17
JP2004510807A (ja) 2004-04-08
US20100234305A1 (en) 2010-09-16
US20030133964A1 (en) 2003-07-17
JP2013253101A (ja) 2013-12-19
SI1322286T1 (en) 2005-10-31
SK287528B6 (sk) 2011-01-04
CN101669900A (zh) 2010-03-17
ATE458469T3 (de) 2010-03-15
DE60141421D1 (de) 2010-04-08
IL155006A0 (en) 2003-10-31
EP1322286B1 (en) 2005-05-25
CZ303134B6 (cs) 2012-04-25
HU228386B1 (hu) 2013-03-28
IL155006A (en) 2007-06-03
ES2241876T7 (es) 2018-02-16
NZ525210A (en) 2004-10-29
US20070104759A1 (en) 2007-05-10
HUP0302981A3 (en) 2006-07-28
DE60111068T2 (de) 2006-01-26

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