|
US6541498B2
(en)
|
1993-05-20 |
2003-04-01 |
Texas Biotechnology |
Benzenesulfonamides and the use thereof to modulate the activity of endothelin
|
|
CN1149196C
(zh)
*
|
1998-07-06 |
2004-05-12 |
布里斯托尔-迈尔斯斯奎布公司 |
作为血管紧张肽和内皮肽受体双重拮抗剂的联苯基磺酰胺
|
|
MY125533A
(en)
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
EP1741713A3
(de)
*
|
1999-12-15 |
2009-09-09 |
Bristol-Myers Squibb Company |
Biphenyl Sulfonamide als zweierlei Angiotensin Endothelin Rezeptor Antagonisten
|
|
WO2001049289A1
(en)
*
|
1999-12-31 |
2001-07-12 |
Texas Biotechnology Corporation |
Pharmaceutical and veterinary uses of endothelin antagonists
|
|
US6271228B1
(en)
*
|
2000-04-28 |
2001-08-07 |
Pfizer Inc. |
Blood pressure stabilization during hemodialysis
|
|
US7622503B2
(en)
|
2000-08-24 |
2009-11-24 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators and methods of use thereof
|
|
AU2002226365A1
(en)
*
|
2000-12-01 |
2002-06-11 |
Novartis Ag |
Combinations of an angiotensin receptor antagonist and an anti-hypertensive drug or a statin, for the treatment of sexual dysfunction
|
|
ES2329881T3
(es)
|
2001-09-21 |
2009-12-02 |
Bristol-Myers Squibb Company |
Compuestos que contienen lactama y derivados de los mismos como inhibidores del factor xa.
|
|
US7238671B2
(en)
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
RU2353625C2
(ru)
|
2001-10-18 |
2009-04-27 |
Бристол-Маерс Сквибб Компани |
Миметики человеческого глюканоподобного пептида-1 и их применение в лечении диабета и родственных состояний
|
|
US8853266B2
(en)
|
2001-12-06 |
2014-10-07 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulators for treating diabetes
|
|
US6831102B2
(en)
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
TWI328007B
(en)
*
|
2002-01-16 |
2010-08-01 |
Astrazeneca Ab |
Novel compounds
|
|
TW200307539A
(en)
|
2002-02-01 |
2003-12-16 |
Bristol Myers Squibb Co |
Cycloalkyl inhibitors of potassium channel function
|
|
US7435824B2
(en)
|
2002-04-19 |
2008-10-14 |
Bristol-Myers Squibb Company |
Prodrugs of potassium channel inhibitors
|
|
TW200403058A
(en)
|
2002-04-19 |
2004-03-01 |
Bristol Myers Squibb Co |
Heterocyclo inhibitors of potassium channel function
|
|
US7405234B2
(en)
|
2002-05-17 |
2008-07-29 |
Bristol-Myers Squibb Company |
Bicyclic modulators of androgen receptor function
|
|
US7057046B2
(en)
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
MY139563A
(en)
|
2002-09-04 |
2009-10-30 |
Bristol Myers Squibb Co |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
|
US6995180B2
(en)
|
2002-10-23 |
2006-02-07 |
Bristol Myers Squibb Company |
Glycinenitrile-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7098235B2
(en)
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US7632858B2
(en)
|
2002-11-15 |
2009-12-15 |
Bristol-Myers Squibb Company |
Open chain prolyl urea-related modulators of androgen receptor function
|
|
TW200504021A
(en)
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
US7557143B2
(en)
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
US6846836B2
(en)
|
2003-04-18 |
2005-01-25 |
Bristol-Myers Squibb Company |
N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase
|
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7820702B2
(en)
|
2004-02-04 |
2010-10-26 |
Bristol-Myers Squibb Company |
Sulfonylpyrrolidine modulators of androgen receptor function and method
|
|
US7378426B2
(en)
|
2004-03-01 |
2008-05-27 |
Bristol-Myers Squibb Company |
Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
|
|
US7696241B2
(en)
|
2004-03-04 |
2010-04-13 |
Bristol-Myers Squibb Company |
Bicyclic compounds as modulators of androgen receptor function and method
|
|
US7625923B2
(en)
|
2004-03-04 |
2009-12-01 |
Bristol-Myers Squibb Company |
Bicyclic modulators of androgen receptor function
|
|
US7772232B2
(en)
|
2004-04-15 |
2010-08-10 |
Bristol-Myers Squibb Company |
Quinazolinyl compounds as inhibitors of potassium channel function
|
|
US7550499B2
(en)
|
2004-05-12 |
2009-06-23 |
Bristol-Myers Squibb Company |
Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
US9884038B2
(en)
|
2004-06-07 |
2018-02-06 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator and methods of use thereof
|
|
US9889110B2
(en)
|
2004-06-07 |
2018-02-13 |
University Of Tennessee Research Foundation |
Selective androgen receptor modulator for treating hormone-related conditions
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
TW200611704A
(en)
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7145040B2
(en)
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
AR051446A1
(es)
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
US7754755B2
(en)
|
2004-09-23 |
2010-07-13 |
Bristol-Myers Squibb Company |
Inhibitors of 15-lipoxygenase
|
|
US7429611B2
(en)
|
2004-09-23 |
2008-09-30 |
Bristol-Myers Squibb Company |
Indole inhibitors of 15-lipoxygenase
|
|
US7517991B2
(en)
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
US8143425B2
(en)
|
2004-10-12 |
2012-03-27 |
Bristol-Myers Squibb Company |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
|
WO2006047415A2
(en)
|
2004-10-26 |
2006-05-04 |
Janssen Pharmaceutica, N.V. |
Factor xa compounds
|
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7589088B2
(en)
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
WO2006076568A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Thiazolopyridines as cannabinoid receptor modulators
|
|
US7314882B2
(en)
|
2005-01-12 |
2008-01-01 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
US7368458B2
(en)
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
JP5236293B2
(ja)
|
2005-01-13 |
2013-07-17 |
ブリストル−マイヤーズ スクイブ カンパニー |
Xia因子阻害剤としての置換ビアリール化合物
|
|
US20060160850A1
(en)
|
2005-01-18 |
2006-07-20 |
Chongqing Sun |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
ATE499370T1
(de)
|
2005-01-19 |
2011-03-15 |
Bristol Myers Squibb Co |
2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3- aminderivate und verwandte verbindungen als p2y1- rezeptor-hemmer zur behandlung thromboembolischer erkrankungen
|
|
ES2319461T3
(es)
|
2005-02-10 |
2009-05-07 |
Bristol-Myers Squibb Company |
Dihidroquinazolinonas como moduladores de 5ht.
|
|
WO2006113261A2
(en)
|
2005-04-14 |
2006-10-26 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type i
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7629342B2
(en)
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
US7452892B2
(en)
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7632837B2
(en)
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
US7572808B2
(en)
|
2005-06-17 |
2009-08-11 |
Bristol-Myers Squibb Company |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US7317012B2
(en)
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
ES2352796T3
(es)
|
2005-06-27 |
2011-02-23 |
Bristol-Myers Squibb Company |
Antagonistas cíclicos unidos a c del receptor p2y1 útiles en el tratamiento de afecciones trombóticas.
|
|
US7816382B2
(en)
|
2005-06-27 |
2010-10-19 |
Bristol-Myers Squibb Company |
Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition
|
|
US7714002B2
(en)
|
2005-06-27 |
2010-05-11 |
Bristol-Myers Squibb Company |
Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
DE602006021306D1
(de)
|
2005-06-27 |
2011-05-26 |
Bristol Myers Squibb Co |
|
|
WO2007005967A2
(en)
*
|
2005-07-05 |
2007-01-11 |
Teva Pharmaceutical Industries Ltd. |
Process for preparing valsartan
|
|
EP1757290A1
(de)
|
2005-08-16 |
2007-02-28 |
Zentaris GmbH |
Triazolderivate als Liganden der Wachstumshormonrezeptoren
|
|
US7795436B2
(en)
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
US7534804B2
(en)
|
2005-08-24 |
2009-05-19 |
Bristol-Myers Squibb Company |
Benzoxazole inhibitors of 15-lipoxygenase
|
|
EP2425715B1
(de)
|
2005-08-31 |
2014-03-05 |
University of Tennessee Research Foundation |
Behandlung von Symptomen von Nierenerkrankungen mithilfe von selektiven Androgenrezeptormodulatoren (SARM)
|
|
AR056155A1
(es)
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
|
US7488725B2
(en)
|
2005-10-31 |
2009-02-10 |
Bristol-Myers Squibb Co. |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7553836B2
(en)
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
MX2008011227A
(es)
*
|
2006-03-03 |
2009-02-10 |
Torrent Pharmaceuticals Ltd |
Receptores antagonistas de accion nueva y doble en los receptores at1 y eta.
|
|
WO2007109456A2
(en)
*
|
2006-03-16 |
2007-09-27 |
Pharmacopeia, Inc. |
Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
WO2007139589A1
(en)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
WO2008008433A2
(en)
|
2006-07-12 |
2008-01-17 |
University Of Tennessee Research Foundation |
Substituted acylanilides and methods of use thereof
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
AU2007303056A1
(en)
|
2006-10-05 |
2008-04-10 |
Gilead Palo Alto, Inc. |
Bicyclic nitrogen-containing heterocyclic compounds for use as stearoyl CoA desaturase inhibitors
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
CN103432133B
(zh)
|
2007-01-22 |
2016-08-10 |
Gtx公司 |
核受体结合剂的用途
|
|
US9604931B2
(en)
|
2007-01-22 |
2017-03-28 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
US9623021B2
(en)
|
2007-01-22 |
2017-04-18 |
Gtx, Inc. |
Nuclear receptor binding agents
|
|
TW200838501A
(en)
*
|
2007-02-02 |
2008-10-01 |
Theravance Inc |
Dual-acting antihypertensive agents
|
|
PE20090185A1
(es)
|
2007-03-22 |
2009-02-28 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
|
US20080255161A1
(en)
*
|
2007-04-11 |
2008-10-16 |
Dmitry Koltun |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
|
|
EP2474549A1
(de)
|
2007-04-17 |
2012-07-11 |
Bristol-Myers Squibb Company |
Kondensierte heterocyclische als Hemmer des 11-Beta-Hydroxysteroid-Dehydrogenase-Typ I
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
MX2009011089A
(es)
|
2007-04-23 |
2009-10-30 |
Sanofi Aventis |
Derivados de quinolina-carboxamida en calidad de antagonistas de p2y12.
|
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
|
PE20090222A1
(es)
|
2007-05-04 |
2009-03-27 |
Bristol Myers Squibb Co |
Compuestos [6,6] y [6,7]-biciclicos como agonistas del receptor acoplado a la proteina g gpr119
|
|
CN101668759A
(zh)
|
2007-05-04 |
2010-03-10 |
百时美施贵宝公司 |
[6,5]-双环gpr119g蛋白-偶合受体激动剂
|
|
TWI406850B
(zh)
|
2007-06-05 |
2013-09-01 |
Theravance Inc |
雙效苯并咪唑抗高血壓劑
|
|
US20090011994A1
(en)
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
TW200904440A
(en)
|
2007-07-17 |
2009-02-01 |
Bristol Myers Squibb Co |
Method for modulating GPR119 G protein-coupled receptor and selected compounds
|
|
CN101808995A
(zh)
|
2007-07-27 |
2010-08-18 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
|
EP2200975A1
(de)
|
2007-09-07 |
2010-06-30 |
Theravance, Inc. |
Blutdrucksenkende mittel mit dualer wirkung
|
|
US7968603B2
(en)
|
2007-09-11 |
2011-06-28 |
University Of Tennessee Research Foundation |
Solid forms of selective androgen receptor modulators
|
|
EP2197873B1
(de)
|
2007-09-20 |
2014-07-16 |
Irm Llc |
Verbindungen und zusammensetzungen als modulatoren der gpr119-aktivität
|
|
JP2011506459A
(ja)
|
2007-12-11 |
2011-03-03 |
セラヴァンス, インコーポレーテッド |
抗高血圧剤としての二重作用性ベンゾイミダゾール誘導体およびその使用
|
|
WO2009080226A2
(en)
|
2007-12-26 |
2009-07-02 |
Sanofis-Aventis |
Heterocyclic pyrazole-carboxamides as p2y12 antagonists
|
|
EP2103602A1
(de)
|
2008-03-17 |
2009-09-23 |
AEterna Zentaris GmbH |
Neuartige 1,2,4-Triazol-Derivate und Herstellungsverfahren dafür
|
|
JP2011518884A
(ja)
|
2008-04-29 |
2011-06-30 |
セラヴァンス, インコーポレーテッド |
二重活性抗高血圧剤
|
|
CA2724430A1
(en)
|
2008-05-19 |
2009-11-26 |
Schering Corporation |
Heterocyclic compounds as factor ixa inhibitors
|
|
PE20091928A1
(es)
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
WO2009155448A1
(en)
*
|
2008-06-20 |
2009-12-23 |
Ligand Pharmaceuticals Inc. |
Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
TW201006821A
(en)
|
2008-07-16 |
2010-02-16 |
Bristol Myers Squibb Co |
Pyridone and pyridazone analogues as GPR119 modulators
|
|
WO2010011821A2
(en)
|
2008-07-24 |
2010-01-28 |
Theravance, Inc. |
Dual-acting antihypertensive agents
|
|
US20100160322A1
(en)
|
2008-12-04 |
2010-06-24 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US8557983B2
(en)
|
2008-12-04 |
2013-10-15 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US8563735B2
(en)
|
2008-12-05 |
2013-10-22 |
Abbvie Inc. |
Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
|
|
US8586754B2
(en)
|
2008-12-05 |
2013-11-19 |
Abbvie Inc. |
BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
|
|
SG174389A1
(en)
*
|
2009-03-17 |
2011-10-28 |
Daiichi Sankyo Co Ltd |
Amide derivative
|
|
CA2756786A1
(en)
|
2009-03-27 |
2010-09-30 |
Bristol-Myers Squibb Company |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
|
PL2732818T3
(pl)
*
|
2009-03-31 |
2017-12-29 |
Ligand Pharmaceuticals Inc. |
Bifenylosulfonamidowy antagonista receptora endoteliny i angiotensyny II do leczenia stwardnienia kłębków nerkowych
|
|
US20220315555A1
(en)
|
2009-05-26 |
2022-10-06 |
Abbvie Inc. |
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US8546399B2
(en)
|
2009-05-26 |
2013-10-01 |
Abbvie Inc. |
Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
US9034875B2
(en)
|
2009-05-26 |
2015-05-19 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
BR122019016429B1
(pt)
|
2009-05-26 |
2020-03-24 |
Abbvie Ireland Unlimited Company |
Compostos inibidores da atividade de proteínas bcl-2 antiapoptótica e composição farmacêutica compreendendo ditos compostos
|
|
SMT202000093T1
(it)
|
2009-06-16 |
2020-03-13 |
Pfizer |
Forme di dosaggio di apixaban
|
|
WO2011005674A1
(en)
|
2009-07-07 |
2011-01-13 |
Theravance, Inc. |
Dual-acting pyrazole antihypertensive agents
|
|
JP2012533626A
(ja)
|
2009-07-22 |
2012-12-27 |
セラヴァンス, インコーポレーテッド |
二重作用オキサゾール降圧剤
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
AR077695A1
(es)
|
2009-08-04 |
2011-09-14 |
Schering Corp |
Derivados de pirimidina como inhibidores del factor ixa
|
|
BR112012008004A2
(pt)
|
2009-10-09 |
2016-03-29 |
Irm Llc |
compostos e composições como moduladores da atividade de gpr119
|
|
ES2693686T3
(es)
|
2009-11-13 |
2018-12-13 |
Astrazeneca Ab |
Formulaciones de comprimidos de liberación inmediata
|
|
BR112012011274A2
(pt)
|
2009-11-13 |
2016-04-12 |
Astrazeneca Uk Ltd |
formulação de metformina de massa reduzida e sua combinação
|
|
WO2011060256A2
(en)
|
2009-11-13 |
2011-05-19 |
Bristol-Myers Squibb Company |
Bilayer tablet formulations
|
|
CN101891735B
(zh)
*
|
2009-11-25 |
2012-07-18 |
北京理工大学 |
联苯磺胺异噁唑类化合物、合成方法及用途
|
|
CN101921265B
(zh)
*
|
2009-11-25 |
2012-07-04 |
北京理工大学 |
联苯酰胺四唑类化合物、合成方法及用途
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US8481549B2
(en)
|
2010-01-19 |
2013-07-09 |
Theravance, Inc. |
Dual-acting thiophene, pyrrole, thiazole and furan antihypertensive agents
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
CA2795732A1
(en)
|
2010-04-08 |
2011-10-13 |
Bristol-Myers Squibb Company |
Pyrimidinylpiperidinyloxypyridinone analogues as gpr119 modulators
|
|
CN102971313A
(zh)
|
2010-04-14 |
2013-03-13 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
|
US8940716B2
(en)
|
2010-05-06 |
2015-01-27 |
Bristol-Myers Squibb Company |
Bicyclic heteroaryl compounds as GPR119 modulators
|
|
EP2566862B1
(de)
|
2010-05-06 |
2015-09-16 |
Bristol-Myers Squibb Company |
Benzofuranyl-analoga als gpr119-modulatoren
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
EP2431035A1
(de)
|
2010-09-16 |
2012-03-21 |
Æterna Zentaris GmbH |
Neue Triazolderivate mit verbesserter Rezeptoraktivität und Bioverfügbarkeitseigenschaften als Ghrelin-Antagonisten der Wachstumshormon-Sekretagogum-Rezeptoren
|
|
UA113500C2
(xx)
|
2010-10-29 |
2017-02-10 |
|
Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
|
|
ES2699205T3
(es)
|
2010-10-29 |
2019-02-07 |
Abbvie Inc |
Dispersiones sólidas que contienen un agente que induce la apoptosis
|
|
AU2011332043C1
(en)
|
2010-11-23 |
2016-11-10 |
Abbvie Inc. |
Salts and crystalline forms of an apoptosis-inducing agent
|
|
NZ708508A
(en)
|
2010-11-23 |
2016-06-24 |
Abbvie Bahamas Ltd |
Methods of treatment using selective bcl-2 inhibitors
|
|
PH12013501345A1
(en)
|
2010-12-23 |
2022-10-24 |
Purdue Pharma Lp |
Tamper resistant solid oral dosage forms
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
|
WO2013068875A1
(en)
|
2011-11-11 |
2013-05-16 |
Pfizer Inc. |
2-thiopyrimidinones
|
|
US9296745B2
(en)
|
2012-04-06 |
2016-03-29 |
Pfizer Inc. |
Diacylglycerol acyltransferase 2 inhibitors
|
|
US9174965B2
(en)
|
2012-05-16 |
2015-11-03 |
Bristol-Myers Squibb Company |
Pyrimidinylpiperidinyloxypyridone analogues as GPR119 modulators
|
|
SI2858987T1
(en)
|
2012-06-11 |
2018-06-29 |
Bristol-Myers Squibb Company |
PREPARATION OF 5-PHENYL-4- (PYRIDIN-2-ILLETHYLAMINO) -CHUINAZOLIN-2-YL) -PIRIDIN-3-SULPHONAMIDE PHOSPHORAMIDIC ACID
|
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
PL2872482T3
(pl)
|
2012-07-13 |
2021-03-08 |
Oncternal Therapeutics, Inc. |
Sposób leczenia raków sutka z użyciem selektywnego modulatora receptora androgenowego (sarm)
|
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
|
LT6043B
(lt)
|
2012-08-27 |
2014-06-25 |
Uab "Mibarsas" |
Organinės trąšos sapropelio pagrindu ir jų gamybos būdas
|
|
WO2014039411A1
(en)
|
2012-09-05 |
2014-03-13 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormore receptor-1 antagonists
|
|
EP2892897A1
(de)
|
2012-09-05 |
2015-07-15 |
Bristol-Myers Squibb Company |
Pyrrolon- oder pyrrolidinon-antagonisten des melaninkonzentrierenden hormonrezeptor-1
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
RU2015123738A
(ru)
|
2012-11-20 |
2017-01-10 |
Лексикон Фармасьютикалз, Инк. |
Ингибиторы котранспортера натрий-глюкозы 1
|
|
JP6386527B2
(ja)
|
2013-03-11 |
2018-09-05 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
カリウムイオンチャネル阻害剤としてのピロロピリダジン
|
|
US9242966B2
(en)
|
2013-03-11 |
2016-01-26 |
Bristol-Myers Squibb Company |
Phthalazines as potassium ion channel inhibitors
|
|
US9050345B2
(en)
|
2013-03-11 |
2015-06-09 |
Bristol-Myers Squibb Company |
Pyrrolotriazines as potassium ion channel inhibitors
|
|
EP2970294B1
(de)
|
2013-03-11 |
2016-12-28 |
Bristol-Myers Squibb Company |
Pyrrolotriazine als kaliumionenkanalhemmer
|
|
EP2970199A1
(de)
|
2013-03-11 |
2016-01-20 |
Bristol-Myers Squibb Company |
Isochinoline als kaliumionenkanalhemmer
|
|
US20140275082A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbvie Inc. |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
|
JP6480909B2
(ja)
*
|
2013-03-15 |
2019-03-13 |
ユニバーシティー オブ サウザン カリフォルニア |
アンギオテンシン関連疾患の処置のための方法、化合物および組成物
|
|
JP6348582B2
(ja)
|
2013-10-09 |
2018-06-27 |
ファイザー・インク |
プロスタグランジンep3受容体の拮抗薬
|
|
US9580422B2
(en)
|
2013-10-22 |
2017-02-28 |
Bristol-Myers Squibb Company |
Isotopically labeled triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
KR101772836B1
(ko)
|
2014-03-17 |
2017-08-29 |
화이자 인코포레이티드 |
대사 및 관련 장애의 치료에 사용하기 위한 디아실글리세롤 아실트랜스퍼라제 2 억제제
|
|
DK3126330T3
(en)
|
2014-04-04 |
2019-04-23 |
Pfizer |
BICYCLE-FUSED HETEROARYL OR ARYL COMPOUNDS AND USE THEREOF AS IRAC4 INHIBITORS
|
|
WO2015160636A1
(en)
|
2014-04-16 |
2015-10-22 |
Merck Sharp & Dohme Corp. |
Factor ixa inhibitors
|
|
JP6649902B2
(ja)
|
2014-05-30 |
2020-02-19 |
ファイザー・インク |
選択的アンドロゲン受容体モジュレーターとしてのカルボニトリル誘導体
|
|
JP2017538769A
(ja)
|
2014-12-22 |
2017-12-28 |
ファイザー・インク |
プロスタグランジンep3受容体の拮抗薬
|
|
CN104761548B
(zh)
*
|
2015-04-27 |
2017-09-12 |
梯尔希(南京)药物研发有限公司 |
一种稳定同位素标记的二苯基磺酰胺类药物的制备方法
|
|
CN107531647A
(zh)
|
2015-05-05 |
2018-01-02 |
辉瑞大药厂 |
2‑硫代嘧啶酮类
|
|
JP2018516254A
(ja)
|
2015-05-29 |
2018-06-21 |
ファイザー・インク |
バニン1酵素の阻害薬としての新規なヘテロ環化合物
|
|
HUE051898T2
(hu)
|
2015-06-17 |
2021-03-29 |
Pfizer |
Triciklusos vegyületek és alkalmazásuk foszfodiészteráz inhibitorokként
|
|
WO2016203335A1
(en)
|
2015-06-18 |
2016-12-22 |
Pfizer Inc. |
Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors
|
|
JP2018527337A
(ja)
|
2015-08-13 |
2018-09-20 |
ファイザー・インク |
二環式縮合ヘテロアリールまたはアリール化合物
|
|
WO2017033093A1
(en)
|
2015-08-27 |
2017-03-02 |
Pfizer Inc. |
Bicyclic-fused heteroaryl or aryl compounds as irak4 modulators
|
|
WO2017037567A1
(en)
|
2015-09-03 |
2017-03-09 |
Pfizer Inc. |
Regulators of frataxin
|
|
CN105481844A
(zh)
*
|
2015-12-08 |
2016-04-13 |
梁彦云 |
一种治疗高血压的药物组合物
|
|
AU2016380920B2
(en)
|
2015-12-29 |
2019-10-31 |
Pfizer Inc. |
Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors
|
|
CN106188115A
(zh)
*
|
2016-07-13 |
2016-12-07 |
北京理工大学 |
廉价高效合成2‑二羟硼基‑n‑二甲异噁唑基‑n‑甲氧乙氧甲基苯磺酰胺的新方法
|
|
CN109476645A
(zh)
|
2016-07-14 |
2019-03-15 |
辉瑞大药厂 |
作为vanin-1酶抑制剂的新的嘧啶甲酰胺
|
|
EP3487862A1
(de)
|
2016-07-22 |
2019-05-29 |
Bristol-Myers Squibb Company |
Glucokinaseaktivatoren und verfahren zur verwendung davon
|
|
AR109179A1
(es)
|
2016-08-19 |
2018-11-07 |
Pfizer |
Inhibidores de diacilglicerol aciltransferasa 2
|
|
CN117085013A
(zh)
|
2016-10-13 |
2023-11-21 |
特拉维尔治疗公司 |
用于治疗肾脏疾病或病症的联苯磺酰胺化合物
|
|
WO2018162625A1
(en)
|
2017-03-09 |
2018-09-13 |
Truly Translational Sweden Ab |
Prodrugs of sulfasalazine, pharmaceutical compositions thereof and their use in the treatment of autoimmune disease
|
|
ES2897200T3
(es)
|
2017-05-31 |
2022-02-28 |
Amplio Pharma Ab |
Una composición farmacéutica que comprende una combinación de metotrexato y novobiocina, y el uso de la composición en terapia
|
|
EP3489222A1
(de)
|
2017-11-23 |
2019-05-29 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Sulfasalazinesalze, herstellungsverfahren und verwendungen
|
|
ES2965337T3
(es)
|
2017-11-23 |
2024-04-12 |
Medac Ges Fuer Klinische Spezialpraeparate Mbh |
Composición farmacéutica para administración oral que contiene sulfasalazina y/o una sal orgánica de sulfasalazina, proceso de producción y uso
|
|
WO2019119673A1
(zh)
|
2017-12-19 |
2019-06-27 |
北京吉源生物科技有限公司 |
一种双基因修饰的干细胞及其用途
|
|
WO2019133445A1
(en)
|
2017-12-28 |
2019-07-04 |
Inception Ibd, Inc. |
Aminothiazoles as inhibitors of vanin-1
|
|
PE20210644A1
(es)
|
2018-07-19 |
2021-03-23 |
Astrazeneca Ab |
METODOS DE TRATAMIENTO DE HFpEF EMPLEANDO DAPAGLIFLOZINA Y COMPOSICIONES QUE COMPRENDEN LA MISMA
|
|
AU2019329884B2
(en)
|
2018-08-31 |
2022-01-27 |
Pfizer Inc. |
Combinations for treatment of NASH/NAFLD and related diseases
|
|
BR112021004839A2
(pt)
|
2018-09-26 |
2021-06-08 |
Lexicon Pharmaceuticals, Inc. |
formas cristalinas de n-(1-((2-(dimetilamino)etil)amino)-2-metil-1-oxopropan-2-il)-4-(4-(2-metil-5-((2s,3r,4r,5s,6r)-3,4,5-triidróxi-6-(metiltio)tetraidro-2h-piran-2-il)benzil)fenil)butanamida e métodos de sua síntese
|
|
MA53817A
(fr)
|
2018-10-04 |
2021-08-11 |
Travere Therapeutics Inc |
Composés biphényl-sulfonamide destinés au traitement de maladies du collagène de type iv
|
|
WO2020102575A1
(en)
|
2018-11-16 |
2020-05-22 |
Inception Ibd, Inc. |
Heterocyclic aminothiazoles and uses thereof
|
|
EP3972596B1
(de)
|
2019-05-20 |
2025-07-16 |
Pfizer Inc. |
Kombinationen mit benzodioxol als glp-1r-agonisten zur verwendung bei der behandlung von nash/nafld und verwandten erkrankungen
|
|
WO2020261144A1
(en)
|
2019-06-28 |
2020-12-30 |
Pfizer Inc. |
5-(thiophen-2-yl)-1h-tetrazole derivatives as bckdk inhibitors useful for treating various diseases
|
|
TW202115086A
(zh)
|
2019-06-28 |
2021-04-16 |
美商輝瑞大藥廠 |
Bckdk抑制劑
|
|
TWI771766B
(zh)
|
2019-10-04 |
2022-07-21 |
美商輝瑞股份有限公司 |
二醯基甘油醯基轉移酶2 抑制劑
|
|
DK4097099T3
(da)
|
2020-02-07 |
2024-07-15 |
Gasherbrum Bio Inc |
Heterocyckliske GLP1-agonister
|
|
JP2022058085A
(ja)
|
2020-02-24 |
2022-04-11 |
ファイザー・インク |
ジアシルグリセロールアシルトランスフェラーゼ2阻害剤とアセチル-CoAカルボキシラーゼ阻害剤との組合せ
|
|
LT4161927T
(lt)
|
2020-06-09 |
2024-09-25 |
Pfizer Inc. |
Spiro junginiai kaip melanokortino receptoriaus antagonistai ir jų panaudojimas
|
|
WO2022022865A1
(en)
|
2020-07-27 |
2022-02-03 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
|
WO2022266370A1
(en)
|
2021-06-17 |
2022-12-22 |
Aria Pharmaceuticals, Inc. |
Sparsentan for treating idiopathic pulmonary fibrosis
|
|
WO2023275715A1
(en)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Metabolites of selective androgen receptor modulators
|
|
US20250066337A1
(en)
|
2021-08-26 |
2025-02-27 |
Pfizer Inc. |
Amorphous Form of (S)-2-(5-((3-Ethoxypyridin-2-YL)Oxy)Pyridin-3-YL)-N-(Tetrahydrofuran-3-YL)Pyrimidine-5-Carboxamide
|
|
WO2023025277A1
(zh)
*
|
2021-08-26 |
2023-03-02 |
上海翰森生物医药科技有限公司 |
含芳环类生物拮抗剂、其制备方法和应用
|
|
WO2023066348A1
(zh)
|
2021-10-21 |
2023-04-27 |
年衍药业(上海)有限公司 |
一种双重拮抗剂及其用途
|
|
IL312296A
(en)
|
2021-12-01 |
2024-06-01 |
Pfizer |
3-PHENYL-1-BENZOTHIOPEN-2-CARBOXYLIC ACID DERIVATIVES AS INHIBITORS OF BRANCHED ALPHA KETO ACID DEHYDROGENSIS KINASE FOR THE TREATMENT OF DIABETES, KIDNEY DISEASES, NASH AND HEART
|
|
ES3039638T3
(en)
|
2021-12-06 |
2025-10-23 |
Pfizer |
Melanocortin 4 receptor antagonists and uses thereof
|
|
CN118510504A
(zh)
|
2022-01-26 |
2024-08-16 |
阿斯利康(瑞典)有限公司 |
用于在治疗糖尿病前期或降低发展2型糖尿病的风险中使用的达格列净
|
|
US20250188103A1
(en)
|
2022-03-09 |
2025-06-12 |
Gasherbrum Bio, Inc. |
Heterocyclic glp-1 agonists
|
|
JP2025513071A
(ja)
|
2022-04-14 |
2025-04-22 |
ガシャーブラム・バイオ・インコーポレイテッド |
ヘテロ環式glp-1アゴニスト
|
|
WO2023224963A1
(en)
*
|
2022-05-16 |
2023-11-23 |
Aria Pharmaceuticals, Inc. |
Dual-acting angiotensin and endothelin receptor antagonists
|
|
JP2025533088A
(ja)
|
2022-10-07 |
2025-10-03 |
ファイザー・インク |
Hsd17b13阻害薬および/または分解薬
|
|
JP2025535295A
(ja)
|
2022-10-18 |
2025-10-24 |
ファイザー・インク |
パタチン様ホスホリパーゼドメイン含有タンパク質3(pnpla3)修飾因子
|
|
US20240182468A1
(en)
|
2022-10-18 |
2024-06-06 |
Pfizer Inc. |
Compounds for the activation of ampk
|
|
CN115745983A
(zh)
*
|
2022-11-23 |
2023-03-07 |
深圳信立泰药业股份有限公司 |
一种血管紧张肽和内皮肽受体拮抗剂及其应用
|
|
CN121002014A
(zh)
|
2022-12-15 |
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