ATE403145T1 - Tragbare vorrichtung mit einer sensor-array- anordnung - Google Patents

Tragbare vorrichtung mit einer sensor-array- anordnung

Info

Publication number
ATE403145T1
ATE403145T1 AT01905306T AT01905306T ATE403145T1 AT E403145 T1 ATE403145 T1 AT E403145T1 AT 01905306 T AT01905306 T AT 01905306T AT 01905306 T AT01905306 T AT 01905306T AT E403145 T1 ATE403145 T1 AT E403145T1
Authority
AT
Austria
Prior art keywords
sensor array
analyte
portable device
array arrangement
particle
Prior art date
Application number
AT01905306T
Other languages
English (en)
Inventor
John Mcdevitt
Eric Anslyn
Jason Shear
Dean Neikirk
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE403145T1 publication Critical patent/ATE403145T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0289Apparatus for withdrawing or distributing predetermined quantities of fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251Colorimeters; Construction thereof
    • G01N21/253Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572Chemical means
    • B01J2219/00576Chemical means fluorophore
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00646Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/00648Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0657Pipetting powder
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12Specific details about manufacturing devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0638Valves, specific forms thereof with moving parts membrane valves, flap valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11Compounds covalently bound to a solid support
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N2001/021Correlating sampling sites with geographical information, e.g. GPS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6421Measuring at two or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6482Sample cells, cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00158Elements containing microarrays, i.e. "biochip"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00564Handling or washing solid phase elements, e.g. beads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • G01N2201/0627Use of several LED's for spectral resolution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Fluid Mechanics (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AT01905306T 2000-01-31 2001-01-31 Tragbare vorrichtung mit einer sensor-array- anordnung ATE403145T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17938000P 2000-01-31 2000-01-31
US17936900P 2000-01-31 2000-01-31
US17929400P 2000-01-31 2000-01-31
US17929300P 2000-01-31 2000-01-31
US17942400P 2000-01-31 2000-01-31
US17929200P 2000-01-31 2000-01-31

Publications (1)

Publication Number Publication Date
ATE403145T1 true ATE403145T1 (de) 2008-08-15

Family

ID=27558697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01905306T ATE403145T1 (de) 2000-01-31 2001-01-31 Tragbare vorrichtung mit einer sensor-array- anordnung

Country Status (7)

Country Link
US (8) US6649403B1 (de)
EP (2) EP2230314A1 (de)
AT (1) ATE403145T1 (de)
AU (5) AU2001233200A1 (de)
CA (1) CA2401782A1 (de)
DE (1) DE60135092D1 (de)
WO (5) WO2001055701A1 (de)

Families Citing this family (519)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE261483T1 (de) 1998-05-05 2004-03-15 Massachusetts Inst Technology Lichtemittierende polymere und vorrichtungen, die diese enthalten
US8198096B2 (en) * 1998-05-05 2012-06-12 Massachusetts Institute Of Technology Emissive polymers and devices incorporating these polymers
US20050147534A1 (en) * 1998-05-05 2005-07-07 Massachusetts Institute Of Technology Emissive sensors and devices incorporating these sensors
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
JP3486557B2 (ja) * 1998-07-30 2004-01-13 宮崎沖電気株式会社 トランスファ成形装置及び半導体装置の製造方法
US6978212B1 (en) * 1999-11-01 2005-12-20 Smiths Detection Inc. System for portable sensing
US6975924B2 (en) * 1999-12-03 2005-12-13 Baxter International Inc. Method and apparatus for controlling the strategy of compounding pharmaceutical admixtures
DE60135092D1 (de) * 2000-01-31 2008-09-11 Univ Texas Tragbare vorrichtung mit einer sensor-array-anordnung
EP1196841A2 (de) * 2000-03-09 2002-04-17 Koninklijke Philips Electronics N.V. Eine familie von komplexen systemen mit geteilter softwarearchitekturfamilie
US7624172B1 (en) 2000-03-17 2009-11-24 Aol Llc State change alerts mechanism
WO2001072002A2 (en) 2000-03-17 2001-09-27 America Online, Inc. Shared groups rostering system
US9246975B2 (en) 2000-03-17 2016-01-26 Facebook, Inc. State change alerts mechanism
US7329489B2 (en) 2000-04-14 2008-02-12 Matabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
WO2001078652A2 (en) 2000-04-14 2001-10-25 Metabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
SE0001790D0 (sv) * 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
WO2003040974A1 (en) * 2000-06-30 2003-05-15 Daikin Industries, Ltd. Sanitary measurement system
AU7189801A (en) * 2000-07-07 2002-01-21 Bristol Myers Squibb Co Electrophysiology configuration suitable for high throughput screening of compounds for drug discovery
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
WO2002009483A1 (en) * 2000-07-26 2002-01-31 The Regents Of The University Of California Manipulation of live cells and inorganic objects with optical micro beam arrays
GB2366011B (en) * 2000-08-14 2004-10-13 Biotrace Ltd Data processing system
US6778724B2 (en) * 2000-11-28 2004-08-17 The Regents Of The University Of California Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
WO2002044689A2 (en) * 2000-11-28 2002-06-06 The Regents Of The University Of California Storing microparticles in optical switch which is transported by micro-fluidic device
JP2004529323A (ja) * 2001-01-31 2004-09-24 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム ミクロ機械加工した化学センサ・アレイ内に材料を閉じ込めるための方法および装置
US7425453B1 (en) * 2001-03-14 2008-09-16 The United States Of America As Represented By The Secretary Of The Navy Integrated circuit porphyrin-based optical Fabry-Perot chemical sensor
DE10117275B4 (de) * 2001-04-06 2005-02-24 Hte Ag The High Throughput Experimentation Company Vorrichtung zur Archivierung und Analyse von Materialien
US20040058407A1 (en) * 2001-04-10 2004-03-25 Miller Scott E. Reactor systems having a light-interacting component
US20040132166A1 (en) * 2001-04-10 2004-07-08 Bioprocessors Corp. Determination and/or control of reactor environmental conditions
US20050032204A1 (en) * 2001-04-10 2005-02-10 Bioprocessors Corp. Microreactor architecture and methods
DE10123259A1 (de) * 2001-05-12 2002-11-21 Eppendorf Ag Mikrofluidisches Speicher- und/oder Dosierbauteil
EP1277438A1 (de) * 2001-07-10 2003-01-22 Agilent Technologies, Inc. (a Delaware corporation) Pflegeplatz Diagnose und/oder Analyse System
US20040146917A1 (en) * 2001-08-03 2004-07-29 Nanosphere, Inc. Nanoparticle imaging system and method
JP4347053B2 (ja) * 2001-08-03 2009-10-21 ナノスフェアー インコーポレイテッド ナノ粒子撮像システムおよび方法
US7253003B2 (en) * 2001-10-19 2007-08-07 Wisconsin Alumni Research Foundation Method for monitoring the environment within a microfluidic device
CA2463741A1 (en) * 2001-10-22 2003-05-01 Merck & Co., Inc. Interactive product selection system
US7304259B2 (en) 2001-11-01 2007-12-04 Siemens Energy & Automation, Inc. Mail processing system with multilevel contaminant detection and sterilization
US20030087455A1 (en) * 2001-11-07 2003-05-08 Eggers Mitchell D Sample carrier system
US7584240B2 (en) 2001-11-07 2009-09-01 Genvault Corporation Automated biological sample archive for storage, retrieval and analysis of large numbers of samples for remote clients
US6989891B2 (en) * 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US7232691B2 (en) * 2001-11-27 2007-06-19 Los Alamos National Security, Llc Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres
US7462325B2 (en) * 2001-11-30 2008-12-09 Nomadics, Inc. Luminescent polymer particles
US20030113730A1 (en) * 2001-12-18 2003-06-19 Daquino Lawrence J. Pulse jet print head having multiple printhead dies and methods for use in the manufacture of biopolymeric arrays
EP1460414B1 (de) * 2001-12-27 2018-09-19 ARKRAY, Inc. Konzentrationsmessverfahren
US6980852B2 (en) * 2002-01-25 2005-12-27 Subqiview Inc. Film barrier dressing for intravascular tissue monitoring system
JP3721334B2 (ja) * 2002-02-01 2005-11-30 富士写真フイルム株式会社 リセプター・リガンド会合反応方法およびそれに用いるリアクタ
US20080172026A1 (en) 2006-10-17 2008-07-17 Blomquist Michael L Insulin pump having a suspension bolus
US7892420B2 (en) * 2004-08-03 2011-02-22 Dornoch Medical Systems, Inc. High volume liquid waste collection and disposal system
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US7057724B1 (en) * 2002-03-21 2006-06-06 Institute Of Critical Care Medicine Particulate info to field units
US20120078075A1 (en) * 2002-04-04 2012-03-29 Maynard John D Determination of a measure of a glycation end-product or disease state using tissue fluorescence in combination with one or more other tests
US20050026134A1 (en) * 2002-04-10 2005-02-03 Bioprocessors Corp. Systems and methods for control of pH and other reactor environment conditions
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
EP1502097A2 (de) * 2002-04-26 2005-02-02 Board of Regents, The University of Texas System Verfahren und system zur detektion von kardialen risikofaktoren
US20050055242A1 (en) * 2002-04-30 2005-03-10 Bryan Bello System and method for medical data tracking, analysis and reporting for healthcare system
US20030215369A1 (en) * 2002-05-17 2003-11-20 Eggers Mitchell D. Sample carrier receiver
EP1364613A1 (de) * 2002-05-23 2003-11-26 FESTO AG & Co Vorrichtung zur Gesundheitsüberprüfung und -überwachung
US7776195B2 (en) * 2002-05-28 2010-08-17 Autogenomics, Inc. Integrated sample processing platform
US7332273B2 (en) * 2002-06-20 2008-02-19 Affymetrix, Inc. Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays
US20070275411A1 (en) 2006-05-25 2007-11-29 Mcgall Glenn H Silane mixtures
US20030003587A1 (en) * 2002-06-28 2003-01-02 Murray George M Molecularly imprinted polymer based sensors for the detection of narcotics
AU2003269913A1 (en) * 2002-07-15 2004-02-02 Massachusetts Institute Of Technology Emissive, high charge transport polymers
AU2003256742A1 (en) 2002-07-24 2004-02-09 Board Of Regents, The University Of Texas System Capture and detection of microbes by membrane methods
US7867754B1 (en) 2002-08-01 2011-01-11 Purdue Research Foundation Microarrays for analyte detection
US7455770B2 (en) * 2002-09-09 2008-11-25 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
WO2004033617A1 (de) * 2002-09-16 2004-04-22 Pan - Biotech Gmbh Zellkulturkammer für ein zellkultursystem
WO2004033616A1 (de) * 2002-09-16 2004-04-22 Pan-Biotech Gmbh Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
WO2004033615A1 (de) * 2002-09-16 2004-04-22 Pan-Biotech Gmbh Verfahren zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
ITTO20020808A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Dispositivo integrato di analisi del dna.
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US7122384B2 (en) * 2002-11-06 2006-10-17 E. I. Du Pont De Nemours And Company Resonant light scattering microparticle methods
US7640306B2 (en) 2002-11-18 2009-12-29 Aol Llc Reconfiguring an electronic message to effect an enhanced notification
US7899862B2 (en) 2002-11-18 2011-03-01 Aol Inc. Dynamic identification of other users to an online user
US7428580B2 (en) 2003-11-26 2008-09-23 Aol Llc Electronic message forwarding
US8965964B1 (en) 2002-11-18 2015-02-24 Facebook, Inc. Managing forwarded electronic messages
AU2003287671A1 (en) 2002-11-18 2004-06-15 America Online, Inc. People lists
US8701014B1 (en) 2002-11-18 2014-04-15 Facebook, Inc. Account linking
US7590696B1 (en) 2002-11-18 2009-09-15 Aol Llc Enhanced buddy list using mobile device identifiers
US8122137B2 (en) 2002-11-18 2012-02-21 Aol Inc. Dynamic location of a subordinate user
US8005919B2 (en) 2002-11-18 2011-08-23 Aol Inc. Host-based intelligent results related to a character stream
AU2003304256A1 (en) * 2002-11-20 2005-01-13 Laser Light Technologies, Inc. An online flow through microchip for detecting hazardous chemical and biological agents in drinking water
US7718442B2 (en) * 2002-11-22 2010-05-18 Genvault Corporation Sealed sample storage element system and method
US7062385B2 (en) * 2002-11-25 2006-06-13 Tufts University Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air
AU2003299576A1 (en) * 2002-11-25 2004-06-18 Tufts University Electro-optical nucleic acid-based sensor array and method for detecting analytes
US20040106114A1 (en) * 2002-12-02 2004-06-03 Eastman Kodak Company Simplified detection process for colored bead random microarrays
US20040121337A1 (en) * 2002-12-19 2004-06-24 Nomadics, Inc. Luminescent polymers and methods of use thereof
WO2004083806A2 (en) 2003-01-22 2004-09-30 University Of South Florida Autonomous genosensor apparatus and methods for use
US7125727B2 (en) * 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
JP2006516743A (ja) * 2003-02-05 2006-07-06 ザ ジェネラル ホスピタル コーポレーション Hiv診断関連用途のためのマイクロチップをベースとしたシステム
US20060228256A1 (en) * 2003-02-07 2006-10-12 Board Of Regents, The University Of Texas System Multi-shell microspheres with integrated chomatographic and detection layers for use in array sensors
US20040162844A1 (en) * 2003-02-13 2004-08-19 J. J. Keller & Associates, Inc. Driver management system and method
US7613776B1 (en) 2003-03-26 2009-11-03 Aol Llc Identifying and using identities deemed to be known to a user
US20050064452A1 (en) * 2003-04-25 2005-03-24 Schmid Matthew J. System and method for the detection of analytes
US20100075858A1 (en) * 2003-04-29 2010-03-25 Genvault Corporation Biological bar code
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
US7651850B2 (en) 2003-05-16 2010-01-26 Board Of Regents, The University Of Texas System Image and part recognition technology
US20040241880A1 (en) * 2003-05-30 2004-12-02 Leproust Eric M. Ligand array assays having reduced fluorescent dye degradation and compositions for practicing the same
US7860727B2 (en) * 2003-07-17 2010-12-28 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US8719053B2 (en) * 2003-07-17 2014-05-06 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US7653693B2 (en) 2003-09-05 2010-01-26 Aol Llc Method and system for capturing instant messages
US7298478B2 (en) 2003-08-14 2007-11-20 Cytonome, Inc. Optical detector for a particle sorting system
AU2004272062B2 (en) * 2003-09-11 2010-08-19 Labrador Diagnostics Llc Medical device for analyte monitoring and drug delivery
US7198855B2 (en) * 2003-09-12 2007-04-03 Becton, Dickinson And Company Methods of surface modification of a flexible substrate to enhance cell adhesion
WO2005031163A1 (en) * 2003-09-25 2005-04-07 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
US7524464B2 (en) 2003-09-26 2009-04-28 Ahn Chong H Smart disposable plastic lab-on-a-chip for point-of-care testing
JP4334969B2 (ja) * 2003-10-02 2009-09-30 パナソニック株式会社 血液成分分析用センサ
US7121647B2 (en) * 2003-10-03 2006-10-17 Lexmark International, Inc. Method of applying an encapsulant material to an ink jet printhead
US7159974B2 (en) * 2003-10-06 2007-01-09 Lexmark International, Inc. Semipermeable membrane for an ink reservoir and method of attaching the same
US7582485B2 (en) * 2003-10-16 2009-09-01 Kimberly-Clark Worldride, Inc. Method and device for detecting ammonia odors and helicobacter pylori urease infection
US20100104473A1 (en) * 2003-11-06 2010-04-29 Kirollos Salama Kirollos Air sampling system and method for calibration
US20050100483A1 (en) * 2003-11-12 2005-05-12 Cytyc Corporation Specimen filter container having data storage
EP2264191A1 (de) * 2003-11-21 2010-12-22 ANP Technologies, Inc. Asymmetrisch verzweigte Polymerkonjugate und Mikroarray-Tests
US7382004B2 (en) * 2003-11-25 2008-06-03 Sensor Electronic Technology, Inc. Semiconductor sensing device
CA2549190A1 (en) * 2003-12-11 2005-06-30 Board Of Regents, The University Of Texas System Method and system for the analysis of saliva using a sensor array
US7122799B2 (en) * 2003-12-18 2006-10-17 Palo Alto Research Center Incorporated LED or laser enabled real-time PCR system and spectrophotometer
US20080044844A1 (en) * 2004-01-27 2008-02-21 Shimshon Belkin Populations Of Cells And Devices And Systems Including Same
US7465210B2 (en) * 2004-02-25 2008-12-16 The Regents Of The University Of California Method of fabricating carbide and nitride nano electron emitters
US7276389B2 (en) * 2004-02-25 2007-10-02 Samsung Electronics Co., Ltd. Article comprising metal oxide nanostructures and method for fabricating such nanostructures
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
CN1690120A (zh) * 2004-03-01 2005-11-02 三菱瓦斯化学株式会社 具有高减震能力的树脂组合物
US7402425B2 (en) * 2004-03-02 2008-07-22 The Charles Stark Draper Laboratory, Inc. Stress-based electrostatic monitoring of chemical reactions and binding
US20050200487A1 (en) * 2004-03-06 2005-09-15 O'donnell Ryan Methods and devices for monitoring the distance between members of a group
TWI233637B (en) * 2004-03-17 2005-06-01 Promos Technologies Inc Method of correcting lithography process and method of forming overlay mark
US7187286B2 (en) * 2004-03-19 2007-03-06 Applera Corporation Methods and systems for using RFID in biological field
US20050216291A1 (en) * 2004-06-16 2005-09-29 Shaheen Elias A Complete mold system
US7230520B2 (en) * 2004-05-03 2007-06-12 Dell Products L.P. Method and apparatus for RF access to system ID and fault information
US7887750B2 (en) * 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
WO2005116081A2 (en) 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
US20070036690A1 (en) * 2004-06-07 2007-02-15 Bioprocessors Corp. Inlet channel volume in a reactor
WO2005120691A1 (en) * 2004-06-07 2005-12-22 Bioprocessors Corp. Reactor mixing
EP1758674A2 (de) * 2004-06-07 2007-03-07 Bioprocessors Corporation Schuberzeugung in einem reaktor
US7910531B2 (en) * 2004-06-17 2011-03-22 C2C Technologies Llc Composition and method for producing colored bubbles
US20050287536A1 (en) * 2004-06-24 2005-12-29 Douglas Kozlay Disposable, multi-use, DNA sample collection disk apparatus for field biohazard testing, DNA testing, and personal authentication
EP1771716A4 (de) 2004-06-29 2012-04-25 Dako Denmark As Verfahren zur vorbehandlung und färbung einer trägervorrichtung für eine biologische probe
US7404613B2 (en) * 2004-06-30 2008-07-29 Lexmark International, Inc. Inkjet print cartridge having an adhesive with improved dimensional control
US20060008919A1 (en) * 2004-07-09 2006-01-12 Boay Yoke P Method and apparatus for detecting gas/radiation that employs color change detection mechanism
WO2006034081A2 (en) * 2004-09-17 2006-03-30 Massachusetts Institute Of Technology Polymers for analyte detection
CA2583406A1 (en) * 2004-09-20 2007-01-04 Boston Microfluidics Microfluidic device for detecting soluble molecules
US20060067650A1 (en) * 2004-09-27 2006-03-30 Clarence Chui Method of making a reflective display device using thin film transistor production techniques
WO2006047371A2 (en) * 2004-10-21 2006-05-04 Englebienne & Associates Stable metal/conductive polymer composite colloids and methods for making and using the same
EP1652911A1 (de) * 2004-10-26 2006-05-03 Konica Minolta Medical & Graphic, Inc. Mikroreaktor für die Inspektion von biologischem Material und Vorrichtung zur Inspektion von biologischem Material
WO2006046588A1 (ja) * 2004-10-28 2006-05-04 Seems Inc. 疾病診断システム
DE102004056735A1 (de) * 2004-11-09 2006-07-20 Clondiag Chip Technologies Gmbh Vorrichtung für die Durchführung und Analyse von Mikroarray-Experimenten
AU2005307747B2 (en) * 2004-11-17 2012-04-05 Gt Acquisition Sub, Inc. Radio frequency animal tracking system
US20070103314A1 (en) * 2004-11-17 2007-05-10 Geissler Randolph K Radio frequency animal tracking system
HU226650B1 (hu) * 2004-11-30 2009-05-28 Vils Ag H Rendszer anyagtárolásra szolgáló teret határoló, a belsõ felén bevonattal ellátott fal vagy/és a bevonat meghibásodásának észlelésére, valamint eljárás a rendszer elõállítására
GB2420850A (en) * 2004-12-03 2006-06-07 Orion Diagnostica Oy Particle based binding assay
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
JP5548337B2 (ja) 2004-12-03 2014-07-16 サイトノーム エスティー リミテッド ライアビリティー カンパニー 微粒子処理用のユニット式カートリッジ
US20060141421A1 (en) * 2004-12-28 2006-06-29 Kimberly-Clark Worldwide, Inc. System and method for detecting substances related to oral health
US7879764B2 (en) * 2004-12-28 2011-02-01 Intel Corporation Electrically active combinatorial chemical (EACC) chip for biochemical analyte detection
US9182480B2 (en) * 2005-01-28 2015-11-10 Hewlett-Packard Development Company, L.P. Information technology (IT) equipment positioning system
US7663092B2 (en) 2005-02-01 2010-02-16 Purdue Research Foundation Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay
US20070023643A1 (en) 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
US8140140B2 (en) * 2005-02-14 2012-03-20 Optiscan Biomedical Corporation Analyte detection system for multiple analytes
US20060235348A1 (en) 2005-02-14 2006-10-19 Callicoat David N Method of extracting and analyzing the composition of bodily fluids
US8251907B2 (en) 2005-02-14 2012-08-28 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US8936755B2 (en) 2005-03-02 2015-01-20 Optiscan Biomedical Corporation Bodily fluid composition analyzer with disposable cassette
US20060183261A1 (en) * 2005-02-15 2006-08-17 Dudenhoefer Christie L Method of forming a biological sensor
US7775370B2 (en) * 2005-03-21 2010-08-17 Utah State University Particle sorting by fluidic vectoring
US20060236470A1 (en) * 2005-03-29 2006-10-26 Sabnis Ram W Novelty compositions with color changing indicator
US20060257439A1 (en) * 2005-03-29 2006-11-16 Sabnis Ram W Cleansing compositions with color changing indicator
US8609025B2 (en) * 2005-03-29 2013-12-17 The Trustees Of The University Of Pennsylvania Single walled carbon nanotubes with functionally adsorbed biopolymers for use as chemical sensors
US20060222601A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Oral care compositions with color changing indicator
WO2006110347A2 (en) * 2005-03-29 2006-10-19 The Trustees Of The University Of Pennsylvania Single walled carbon nanotubes functionally adsorbed to biopolymers for use as chemical sensors
US20060222675A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Personal care compositions with color changing indicator
US7682816B2 (en) * 2005-04-07 2010-03-23 454 Life Sciences Corporation Thin film coated microwell arrays and methods of using same
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
US20100245803A1 (en) * 2005-04-12 2010-09-30 Chromedx Inc. Blood sample holder for spectroscopic analysis
CA2517299A1 (en) * 2005-08-26 2007-02-26 Chromedx Inc. Hollow needle assembly
CA2507323A1 (en) * 2005-05-13 2006-11-13 Chromedx Inc. Diagnostic whole blood and plasma apparatus
US7740804B2 (en) * 2005-04-12 2010-06-22 Chromedx Inc. Spectroscopic sample holder
US7846716B2 (en) * 2005-04-28 2010-12-07 Fujifilm Corporation Microchip and analysis method using the same
CA2610294C (en) 2005-05-09 2023-10-03 Theranos, Inc. Point-of-care fluidic systems and uses thereof
JP2006322841A (ja) * 2005-05-19 2006-11-30 Shimadzu Corp 分光測定方法及び分光光度計
US8076143B2 (en) * 2005-05-25 2011-12-13 Westfall Geofrey J Method for determining quality of milk and presence of mastitis
US20060267731A1 (en) * 2005-05-31 2006-11-30 Chen Thomas C H System and apparatus of Internet-linked RFID sensor network for object identifying, sensing, monitoring, tracking and networking
US8377398B2 (en) 2005-05-31 2013-02-19 The Board Of Regents Of The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
WO2006132666A1 (en) * 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
US7456960B2 (en) * 2005-06-06 2008-11-25 Particle Measuring Systems, Inc. Particle counter with improved image sensor array
US7749531B2 (en) * 2005-06-08 2010-07-06 Indicator Systems International Apparatus and method for detecting bacterial growth beneath a wound dressing
USD537913S1 (en) 2005-06-22 2007-03-06 Hitek Aqua Systems, Llc Floating housing
US7681436B2 (en) * 2005-06-22 2010-03-23 Hitek Aqua Systems, Llc In-situ water analysis method and system
WO2007002480A2 (en) 2005-06-24 2007-01-04 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US7409853B2 (en) * 2005-06-30 2008-08-12 Hitek Aqua Systems, Llc Floatable housing for in situ water monitoring system
WO2007005666A2 (en) * 2005-07-01 2007-01-11 Board Of Regents, The University Of Texas System System and method of analyte detection using differential receptors
US20070010400A1 (en) * 2005-07-06 2007-01-11 Sabnis Ram W Use of color changing indicators in consumer products
US8287818B2 (en) * 2005-07-18 2012-10-16 Kantrowitz Allen B Modular hospital cart
JP4764969B2 (ja) * 2005-07-25 2011-09-07 ローム株式会社 マイクロチップ測定装置
US7791728B2 (en) * 2005-08-11 2010-09-07 Hewlett-Packard Development Company, L.P. System for optically analyzing a substance with a selected single-wavelength
WO2007022483A2 (en) * 2005-08-19 2007-02-22 Bioventures, Inc. Method and device for the collection and isolation of nucleic acid
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US7556776B2 (en) * 2005-09-08 2009-07-07 President And Fellows Of Harvard College Microfluidic manipulation of fluids and reactions
US7544330B2 (en) * 2005-09-28 2009-06-09 Idexx Laboratories, Inc. Microplate sample tracking system
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US20070141597A1 (en) * 2005-10-25 2007-06-21 Harmon H J Biomimetic Biodetector of Toxins, Viruses, Bacteria, and Biological Factors
CA2631248C (en) * 2005-11-28 2016-01-12 Pacific Biosciences Of California, Inc. Uniform surfaces for hybrid material substrates and methods for making and using same
US20080241910A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for pathogen detection
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US7405417B2 (en) * 2005-12-20 2008-07-29 Asml Netherlands B.V. Lithographic apparatus having a monitoring device for detecting contamination
US7649359B2 (en) * 2005-12-27 2010-01-19 The Curators Of The University Of Missouri Electrostatic thin film chemical and biological sensor
FR2895667B3 (fr) * 2006-01-05 2008-04-04 Rene Vinci Detecteur de fecondite pour mammiferes
US20070158804A1 (en) * 2006-01-10 2007-07-12 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device, manufacturing method of semiconductor device, and RFID tag
DE102006002093B4 (de) * 2006-01-17 2010-11-25 Airbus Deutschland Gmbh Vorrichtung zur Erfassung von Konturabweichungen eines flexiblen Bauteils unter Berücksichtigung des Bauteileigengewichts sowie Verfahren
US20080175963A1 (en) * 2006-01-26 2008-07-24 Bunn-O-Matic Corporation Beverage Freshness Detecting and Indicating Systems
US7652268B2 (en) * 2006-01-31 2010-01-26 Jp Laboratories, Inc General purpose, high accuracy dosimeter reader
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US8492098B2 (en) * 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
US8064722B1 (en) * 2006-03-07 2011-11-22 The United States Of America As Represented By The Secretary Of The Navy Method and system for analyzing signal-vector data for pattern recognition from first order sensors
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US20100230610A1 (en) * 2006-03-28 2010-09-16 Koninklijke Philips Electronics N.V. Integrated device having an array of photodetectors and an array of sample sites
US20100120132A1 (en) * 2006-03-31 2010-05-13 Intel Corporation Bioassays by direct optical detection of nanoparticles
JP2009533676A (ja) * 2006-04-13 2009-09-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 手持ち式ガス検知器およびガス検知方法
US7734131B2 (en) * 2006-04-18 2010-06-08 Xerox Corporation Fabry-Perot tunable filter using a bonded pair of transparent substrates
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
WO2007134189A2 (en) 2006-05-10 2007-11-22 Board Of Regents, The University Of Texas System Detecting tumor biomarker in oral cancer
US8137626B2 (en) 2006-05-19 2012-03-20 California Institute Of Technology Fluorescence detector, filter device and related methods
EP1870027A1 (de) * 2006-06-21 2007-12-26 Trace Analytics GmbH Vorrichtungen und Verfahren zum Nachweisen eines Analyten
US7549349B2 (en) * 2006-06-22 2009-06-23 Evogen, Inc. Sample cartridge for air-sampling device
EP2041556A1 (de) * 2006-06-28 2009-04-01 RGB Technologies AB Sensorkit und system zum nachweis eines analyten in einer testumgebung
JP4145938B2 (ja) * 2006-06-28 2008-09-03 株式会社オンチップ・バイオテクノロジーズ 細胞分離チップおよびこれを使用した細胞培養方法
US20080004504A1 (en) * 2006-06-30 2008-01-03 Kimmo Uutela System for detecting allergic reactions resulting from a chemical substance given to a patient
US20080026373A1 (en) * 2006-07-26 2008-01-31 Rodionova Natalia A Assays Based On Light Emission From Analyte Complexes Within A Cassette
ES2688281T3 (es) 2006-07-28 2018-10-31 Diagnostics For The Real World, Ltd Dispositivo, sistema y método para procesar una muestra
WO2008019086A2 (en) * 2006-08-04 2008-02-14 Massachusetts Institute Of Technology Detection of explosives, toxins and other compositions
WO2008033575A2 (en) 2006-09-15 2008-03-20 Metabolon, Inc. Methods of identifying biochemical pathways
WO2008036614A1 (en) * 2006-09-18 2008-03-27 California Institute Of Technology Apparatus for detecting target molecules and related methods
US7890463B2 (en) * 2006-09-28 2011-02-15 Xeround Systems Ltd. Apparatus and method for a distributed storage global database
US8283423B2 (en) 2006-09-29 2012-10-09 Massachusetts Institute Of Technology Polymer synthetic technique
US8802447B2 (en) * 2006-10-05 2014-08-12 Massachusetts Institute Of Technology Emissive compositions with internal standard and related techniques
US20080161204A1 (en) * 2006-10-06 2008-07-03 Mo-Huang Li Microwell array for parallel synthesis of chain molecules
US20080084559A1 (en) * 2006-10-10 2008-04-10 C Technologies, Inc. Microvolume sampling device
US20090215189A1 (en) 2006-10-27 2009-08-27 Massachusetts Institute Of Technology Sensor of species including toxins and chemical warfare agents
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8701469B2 (en) 2006-11-21 2014-04-22 Cornell University Flexible substrate sensor system for environmental and infrastructure monitoring
US7522282B2 (en) 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
US9273345B2 (en) * 2006-12-28 2016-03-01 Conceptual Mindworks, Inc. Methods and compositions for processes of rapid selection and production of nucleic acid aptamers
US8323982B2 (en) 2007-01-11 2012-12-04 Valencell, Inc. Photoelectrocatalytic fluid analyte sensors and methods of fabricating and using same
WO2008089282A2 (en) * 2007-01-16 2008-07-24 Silver James H Sensors for detecting subtances indicative of stroke, ischemia, infection or inflammation
US9945789B2 (en) 2007-01-16 2018-04-17 Alverix, Inc. Multiple analyte detection systems and methods of detecting multiple analytes
WO2008089495A2 (en) 2007-01-19 2008-07-24 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
AU2008206058B2 (en) 2007-01-21 2013-07-04 Allflex USA LLC Animal management system including radio animal tag and additional transceiver(s)
US8617903B2 (en) * 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US20080180259A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for allergen detection
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
US10001496B2 (en) * 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US20080181816A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Systems for allergen detection
US8168140B2 (en) * 2007-01-31 2012-05-01 Agilent Technologies, Inc. Microfluidic apparatuses with nanochannels
WO2008118934A1 (en) 2007-03-26 2008-10-02 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
US20090227005A1 (en) * 2007-03-27 2009-09-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US20080243865A1 (en) * 2007-03-28 2008-10-02 Oracle International Corporation Maintaining global state of distributed transaction managed by an external transaction manager for clustered database systems
CA2697357A1 (en) * 2007-04-16 2008-10-30 John T. Mcdevitt Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
CN101668590A (zh) * 2007-04-25 2010-03-10 3M创新有限公司 化学组分和处理装置组件
US20110020947A1 (en) * 2007-04-25 2011-01-27 3M Innovative Properties Company Chemical component and processing device assembly
US8597190B2 (en) 2007-05-18 2013-12-03 Optiscan Biomedical Corporation Monitoring systems and methods with fast initialization
KR100903969B1 (ko) * 2007-06-12 2009-06-25 삼성전자주식회사 마이크로 어레이, 마이크로 어레이용 기판 및 이들의 제조방법
US20090014340A1 (en) * 2007-06-15 2009-01-15 Williams John R Devices, systems, and methods for measuring glucose
WO2009002447A1 (en) 2007-06-21 2008-12-31 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
USD591012S1 (en) 2007-06-25 2009-04-21 Destron Fearing Corporation Animal ear tag
WO2009006456A1 (en) * 2007-06-29 2009-01-08 The Trustees Of Columbia University Microfluidic device for counting biological particles
US8921121B2 (en) * 2007-06-29 2014-12-30 The Trustees Of Columbia University In The City Of New York Methods, devices, and systems for chemiluminescence-based microfluidic cell counting
US8790877B2 (en) * 2007-07-12 2014-07-29 The United States Of America As Represented By The Secretary Of The Air Force Using DNA aptamers and quantum dots for the detection of proteins or other targets
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
GB2456079B (en) 2007-08-17 2010-07-14 Diagnostics For The Real World Device, system and method for processing a sample
EP2201374B1 (de) 2007-08-30 2015-10-07 Trustees Of Tufts College Verfahren zur bestimmung der konzentration eines analyten in lösung
US8318107B2 (en) * 2007-09-05 2012-11-27 Biosense Technologies, Inc. Apparatus and method for specimen suitability testing
EP2237687B1 (de) * 2007-09-06 2016-08-03 Fredrica V. Coates Kleinkindwickeltuch mit körperpolsterung
EP2185922A4 (de) * 2007-09-10 2014-03-05 Univ Hong Kong Elektronischer zungensensor
GB0719373D0 (en) * 2007-10-04 2007-11-14 Univ Cranfield Optical multisensor
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
US7978079B2 (en) * 2007-10-12 2011-07-12 Destron Fearing Corporation Electronic tag
US20090148342A1 (en) * 2007-10-29 2009-06-11 Bromberg Steven E Hypochlorite Technology
WO2009061864A1 (en) * 2007-11-06 2009-05-14 3M Innovative Properties Company Processing device tablet
WO2009061831A1 (en) * 2007-11-08 2009-05-14 Indicator Systems International, Inc. Polymeric indicators for detecting the presence of metabolic byproducts from microorganisms
WO2009079156A2 (en) * 2007-11-20 2009-06-25 3M Innovative Properties Company Detection devices and methods
US20140236351A1 (en) * 2007-11-29 2014-08-21 Searete Llc Programmed Dispensing of Consumable Compositions
WO2009073652A1 (en) 2007-12-04 2009-06-11 Particle Measuring Systems, Inc. Two-dimensional optical imaging methods and systems for particle detection
US7897410B2 (en) * 2007-12-18 2011-03-01 Texas Instruments Incorporated Close proximity scanning surface contamination analyzer
WO2009079857A1 (en) 2007-12-24 2009-07-02 Honeywell International Inc. A reactor for the quantitative analysis of nucleic acids
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
WO2009094773A1 (en) * 2008-01-31 2009-08-06 Genesis Group Inc. Method of depositing a polymer micropattern on a substrate
JP5283924B2 (ja) * 2008-02-21 2013-09-04 株式会社日立製作所 核酸増幅用デバイス
WO2009134395A2 (en) * 2008-04-28 2009-11-05 President And Fellows Of Harvard College Microfluidic device for storage and well-defined arrangement of droplets
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
US9394184B1 (en) 2008-04-30 2016-07-19 Hitek Aqua Systems System for and method of regulating calcium hardness for a body of water
WO2009135117A1 (en) * 2008-05-02 2009-11-05 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Selective membranes/thin films for analytical applications
US9503526B2 (en) 2008-05-19 2016-11-22 Tandem Diabetes Care, Inc. Therapy management system
US8181531B2 (en) * 2008-06-27 2012-05-22 Edwin Carlen Accessible stress-based electrostatic monitoring of chemical reactions and binding
US9011670B2 (en) * 2008-08-14 2015-04-21 The Charles Stark Draper Laboratory, Inc. Three-dimensional metal ion sensor arrays on printed circuit boards
US8939966B2 (en) * 2008-08-21 2015-01-27 University Of Florida Research Foundation, Inc. Differential laser-induced perturbation (DLIP) for bioimaging and chemical sensing
ES2592205T3 (es) * 2008-09-04 2016-11-28 The Board Of Trustees Of The University Of Illinois Matrices de sensores colorimétricos basados en pigmentos nanoporosos
US20100058834A1 (en) * 2008-09-09 2010-03-11 Honeywell International Inc. Method and apparatus for low drift chemical sensor array
WO2010031007A2 (en) 2008-09-12 2010-03-18 Genvault Corporation Matrices and media for storage and stabilization of biomolecules
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
AU2009293019A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care Inc. Solute concentration measurement device and related methods
US20100075439A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification
US20100075862A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample
US8222047B2 (en) * 2008-09-23 2012-07-17 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays
CN102227659B (zh) * 2008-09-30 2014-12-24 加利福尼亚太平洋生物科学股份有限公司 超高多路分析系统和方法
US7923715B2 (en) * 2008-12-06 2011-04-12 The United States Of America As Represented By The Administrator Of National Aeronautics And Space Administration Chalcogenide nanoionic-based radio frequency switch
US20100147832A1 (en) * 2008-12-16 2010-06-17 Barker Iii Charles R Induction cookware identifying
US20100179074A1 (en) * 2009-01-15 2010-07-15 Honeywell International Inc. Methods and apparatus for fluid delivery and removal of micron scale structures
AU2010206580A1 (en) * 2009-01-26 2011-08-11 Indicator Systems International, Inc. Indicators for detecting the presence of metabolic byproducts from microorganisms
US20110287409A1 (en) * 2009-02-05 2011-11-24 Hydradx, Inc. Diagnostic device and method
EP2221606A3 (de) * 2009-02-11 2012-06-06 Samsung Electronics Co., Ltd. Integrierter Biochip und Verfahren zur Herstellung des integrierten Biochips
JP4849278B2 (ja) * 2009-03-27 2012-01-11 セイコーエプソン株式会社 細胞処理デバイス、細胞処理カートリッジおよび体液処理システム
FI20095501A0 (fi) 2009-05-04 2009-05-04 Pekka Haenninen Menetelmä näytteiden karakterisoimiseksi ja/tai määrittämiseksi
US20120224053A1 (en) * 2009-06-17 2012-09-06 Board Of Regents, The University Of Texas System Method and apparatus for quantitative microimaging
EP2449129B1 (de) * 2009-07-01 2014-04-16 Board Of Regents, The University Of Texas System Verfahren zur bestimmung des vorhandenseins und/oder der konzentration eines analyts in einer probe
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
US8731638B2 (en) 2009-07-20 2014-05-20 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
GB0913258D0 (en) 2009-07-29 2009-09-02 Dynex Technologies Inc Reagent dispenser
US9523701B2 (en) 2009-07-29 2016-12-20 Dynex Technologies, Inc. Sample plate systems and methods
EP3284494A1 (de) 2009-07-30 2018-02-21 Tandem Diabetes Care, Inc. Tragbares infusionspumpensystem
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8248255B2 (en) * 2009-10-13 2012-08-21 Verifuel Ltd. Optical fluid tester
WO2011049886A1 (en) 2009-10-19 2011-04-28 Theranos, Inc. Integrated health data capture and analysis system
WO2011053845A2 (en) * 2009-10-30 2011-05-05 Illumina, Inc. Microvessels, microparticles, and methods of manufacturing and using the same
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US10022696B2 (en) 2009-11-23 2018-07-17 Cyvek, Inc. Microfluidic assay systems employing micro-particles and methods of manufacture
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
JP5701894B2 (ja) 2009-11-23 2015-04-15 サイヴェク・インコーポレイテッド アッセイを行う方法及び装置
WO2013134744A2 (en) 2012-03-08 2013-09-12 Cyvek, Inc Microfluidic assay assemblies and methods of manufacture
EP2513626A2 (de) 2009-12-15 2012-10-24 Nomadics, Inc. System und verfahren zur erkennung mehrerer analyte
JP5663985B2 (ja) * 2009-12-16 2015-02-04 ソニー株式会社 マイクロビーズ検査用のセル及びマイクロビーズの解析方法
US8702941B2 (en) * 2009-12-25 2014-04-22 ARKARY, Inc. Method of analyzing hemoglobin by electrophoresis
US8640525B2 (en) * 2009-12-30 2014-02-04 Monsanto Technology Llc Methods and systems for differentiating soybeans
CN102791882A (zh) 2010-01-20 2012-11-21 霍尼韦尔国际公司 用于核酸定量分析的反应器
US8338182B2 (en) * 2010-02-08 2012-12-25 Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University Methods and systems for fluid examination and remediation
US8415171B2 (en) 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9110025B2 (en) 2010-03-01 2015-08-18 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US9678068B2 (en) * 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US20110282247A1 (en) * 2010-03-31 2011-11-17 Helen Denise Novel Ovulation Predictor Device
US8363224B2 (en) 2010-03-31 2013-01-29 General Electric Company Fringe locking subsystem and methods of making and using the same
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
CA2799468A1 (en) 2010-05-14 2011-11-17 Mallinckrodt Llc Functional, cross-linked nanostructures for tandem optical imaging and therapy
EP2580589B1 (de) 2010-06-09 2016-08-31 Optiscan Biomedical Corporation Messung von analyten in einer flüssigkeitsprobe aus einem patienten
EP2397859B1 (de) 2010-06-15 2020-02-05 F. Hoffmann-La Roche AG Optische Überwachung des Mischens und Trennens
US20110312748A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc with integral photosensor for detection of hybridization assay results
WO2012050646A2 (en) 2010-06-29 2012-04-19 The Trustees Of The University Of Pennsylvania Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
RU2535880C2 (ru) * 2010-07-29 2014-12-20 Динекс Текнолоджиз, Инк. Планшет для образцов, его применение и способ фиксации гранулы или микросферы реагента в планшете для образцов
US9671413B2 (en) 2010-11-12 2017-06-06 William Marsh Rice University Prostate cancer point of care diagnostics
WO2012065117A2 (en) 2010-11-12 2012-05-18 William Marsh Rice University Oral cancer point of care diagnostics
KR101037099B1 (ko) 2010-11-30 2011-05-25 주식회사 이바이오젠 비드챔버를 이용한 진동 교잡 바이오칩 반응 시스템
US8586913B2 (en) 2011-01-10 2013-11-19 Schlumberger Technology Corporation Fluidic density measurements based on beta particles detection
EP2481703B1 (de) * 2011-01-27 2020-07-01 Sensirion AG Sensorschutz
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
JP5978287B2 (ja) 2011-03-22 2016-08-24 サイヴェク・インコーポレイテッド マイクロ流体装置並びに製造及び使用の方法
US9828696B2 (en) * 2011-03-23 2017-11-28 Nanohmics, Inc. Method for assembly of analyte filter arrays using biomolecules
US9252175B2 (en) 2011-03-23 2016-02-02 Nanohmics, Inc. Method for assembly of spectroscopic filter arrays using biomolecules
WO2012142301A2 (en) 2011-04-12 2012-10-18 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US20120288866A1 (en) * 2011-05-11 2012-11-15 Genturadx, Inc. Systems and methods for producing an evaporation barrier in a reaction chamber
WO2012154306A1 (en) 2011-05-12 2012-11-15 William Marsh Rice University Bio-nano-chips for on-site drug screening
DE102011050389B4 (de) 2011-05-16 2021-09-02 Presens - Precision Sensing Gmbh Sensoreinheit und Messverfahren
US8660968B2 (en) * 2011-05-25 2014-02-25 Azure Vault Ltd. Remote chemical assay classification
JP5765081B2 (ja) * 2011-06-22 2015-08-19 ソニー株式会社 撮像素子、電子機器、製造方法、および検査装置
ITTO20110567A1 (it) * 2011-06-28 2012-12-29 St Microelectronics Srl Cartuccia per analisi biochimiche, sistema per analisi biochimiche e metodo per eseguire un processo biochimico
EP2729784A4 (de) 2011-07-06 2015-05-13 Optiscan Biomedical Corp Messzelle für flüssigkeitsanalysesystem
KR101312272B1 (ko) * 2011-08-09 2013-09-25 삼성에스디아이 주식회사 광전변환소자
US10983117B2 (en) 2011-08-31 2021-04-20 The Trustees Of The University Of Pennsylvania Carbon nanotube biosensors and related methods
US20130078615A1 (en) * 2011-09-26 2013-03-28 Alberto Gandini Device and Method for Detection and Quantification of Immunological Proteins, Pathogenic and Microbial Agents and Cells
US20130092846A1 (en) * 2011-10-18 2013-04-18 Uwm Research Foundation, Inc. Fiber-optic sensors for real-time monitoring
KR101876540B1 (ko) 2011-12-28 2018-07-10 삼성디스플레이 주식회사 가요성 표시 장치 및 가요성 표시 장치의 제조 방법
US9075021B2 (en) 2012-02-17 2015-07-07 Toyota Motor Engineering & Manufacturing North America, Inc. Methods and systems for monitoring content of coating solutions using automated titration devices
US8850689B2 (en) * 2012-03-23 2014-10-07 Delta Electronics, Inc. Method for manufacturing switchable particle-based display using a pre-filling process
WO2013158504A1 (en) * 2012-04-17 2013-10-24 Ehrenkranz Joel R L Device for performing diagnostic test and methods for use thereof
US10132802B2 (en) 2012-04-17 2018-11-20 i-calQ, LLC Device for performing a diagnostic test and methods for use thereof
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
GB2502306A (en) * 2012-05-22 2013-11-27 Univ Singapore Microparticle sensor
IN2014MN02555A (de) * 2012-06-01 2015-07-24 Vycap B V
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
CN104620113B (zh) * 2012-08-31 2017-02-22 国立大学法人东京大学 检测装置及检测方法
US9310357B2 (en) 2012-09-28 2016-04-12 Src, Inc. Detection of chemical and biological agents using oligonucleotide aptamers
EP3511423B2 (de) 2012-10-17 2024-05-29 Spatial Transcriptomics AB Verfahren und produkt zur optimierung einer lokalisierten oder räumlichen detektion einer genexpression in einer gewebeprobe
WO2014113502A1 (en) 2013-01-15 2014-07-24 Quanterix Corporation Detection of dna or rna using single molecule arrays and other techniques
EP2948772B1 (de) * 2013-01-22 2018-10-10 Nitto Denko Corporation Hydrogel zur verwendung in einem biosensor mit optikbasiertem nachweis von analyten
EP2763065A1 (de) * 2013-01-31 2014-08-06 Sensirion AG Verfahren und System zur Identifizierung einer Flüssigkeitsprobe
WO2014121802A1 (en) * 2013-02-07 2014-08-14 Zaghloul Mohammad Hosam Eldeen Innovative nano-elisa single test for the detection of hcv, hiv antibodies and hbsag
US8995658B2 (en) 2013-02-13 2015-03-31 Honeywell International Inc. Physics-based key generation
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9492608B2 (en) 2013-03-15 2016-11-15 Tandem Diabetes Care, Inc. Method and device utilizing insulin delivery protocols
US9097712B2 (en) * 2013-03-15 2015-08-04 Allied Innovative Systems Llc Flow-through cell counting assay
US9248448B2 (en) 2013-04-24 2016-02-02 William Marsh Rice University Multisample bionanochip platform
ITVR20130132A1 (it) * 2013-05-29 2014-11-30 Optoelettronica Italia S R L Kit per il rilevamento di micro-rna estratto da un campione di fluido corporeo nonché metodo per il rilevamento dello stesso
GB2515490A (en) * 2013-06-24 2014-12-31 Univ Dublin City An aperture array substrate device, a detection system and a method for detecting analytes in a sample
LT3013983T (lt) 2013-06-25 2023-05-10 Prognosys Biosciences, Inc. Erdviniai koduoti biologiniai tyrimai, naudojant mikrofluidinį įrenginį
GB201315327D0 (en) * 2013-08-28 2013-10-09 Anmat Technology Ltd Apparatus for detecting an analyte using a fluid having magnetic particles with a binding ligand for binding the analyte
CN103487880B (zh) * 2013-09-30 2016-05-25 南京华信藤仓光通信有限公司 使光纤束中光纤或光纤并带易剥离方法及硅油涂覆的装置
US9465960B2 (en) 2013-12-04 2016-10-11 Honeywell International Inc. Physics-based authentication
US10109612B2 (en) * 2013-12-13 2018-10-23 Taiwan Semiconductor Manufacturing Company Tools and systems for processing semiconductor devices, and methods of processing semiconductor devices
WO2015095239A1 (en) 2013-12-18 2015-06-25 Optiscan Biomedical Corporation Systems and methods for detecting leaks
TW201527756A (zh) * 2014-01-10 2015-07-16 Nat Univ Tsing Hua 提供食品安全地圖之方法、電腦程式產品、和系統
WO2015115471A1 (ja) * 2014-01-28 2015-08-06 国立大学法人大阪大学 観察装置、デバイス、デバイス製造方法、粒径測定方法、耐性観察方法、化学的反応方法、粒子保存方法、及び自動観察装置
EP3859301A1 (de) * 2014-02-11 2021-08-04 Wallac OY Vorrichtung und verfaren zur verwaltung einer analysierenden probe und ein festprobenträger und flüssigprobenträger
DE102014203266B4 (de) * 2014-02-24 2018-07-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit FRET-Paar in definierter Geometrie
JP6480210B2 (ja) * 2014-02-28 2019-03-06 アークレイ株式会社 プラズマ発生用チップ、プラズマ発生装置およびプラズマ分光分析方法
GB2524541A (en) * 2014-03-26 2015-09-30 Ibm Microfluidic chip with conic bead trapping cavities and fabrication thereof
DE102014104595A1 (de) * 2014-04-01 2015-10-01 Michael Himmelhaus Verfahren und Vorrichtung zur labelfreien Detektion eines Analyten
WO2015187814A1 (en) * 2014-06-03 2015-12-10 Protochips, Inc. Method for optimizing fluid flow across a sample within an electron microscope sample holder
US10031104B2 (en) * 2014-06-13 2018-07-24 Yes Way Intellectual Holdings, Llc Mobile micro-lab for chemical analysis of fluids
US10309976B2 (en) 2014-06-30 2019-06-04 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
CN106662596A (zh) 2014-06-30 2017-05-10 松下健康医疗控股株式会社 试样分析用基板和试样分析装置
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
JP6588909B2 (ja) 2014-06-30 2019-10-09 Phcホールディングス株式会社 試料分析用基板、試料分析システムおよび磁性粒子を含む液体から液体を取り除く方法
US10416144B2 (en) 2014-07-28 2019-09-17 Kansas State University Research Foundation Nanosensors for detecting enzymatic activity in dairy production
EP3180613B1 (de) * 2014-08-11 2023-10-18 The Regents of The University of California Kontinuierlicher analytsensor
WO2016036950A1 (en) 2014-09-05 2016-03-10 The Trustees Of The University Of Pennsylvania Volatile organic compound-based diagnostic systems and methods
KR102603422B1 (ko) 2014-09-29 2023-11-17 애버리 데니슨 코포레이션 타이어 트래킹 rfid 라벨
CN104406916A (zh) * 2014-11-04 2015-03-11 百度在线网络技术(北京)有限公司 食物的检测方法和装置
WO2016093332A1 (ja) 2014-12-12 2016-06-16 パナソニックヘルスケアホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
US10875023B2 (en) * 2015-01-07 2020-12-29 Personal Genomics, Inc. Oriented loading systems and method for orienting a particle loaded in a well
DE102015001998B3 (de) * 2015-02-20 2016-02-04 Friz Biochem Gesellschaft Für Bioanalytik Mbh Mikrofluidische Kartusche für den Nachweis von Biomolekülen
WO2016145300A1 (en) * 2015-03-11 2016-09-15 Nano Engineered Applications, Inc. Chemical sensor
BR112017021256A2 (pt) * 2015-04-03 2018-06-26 Abbott Laboratories dispositivos e métodos para a análise de amostras
SG11201707515SA (en) 2015-04-10 2017-10-30 Spatial Transcriptomics Ab Spatially distinguished, multiplex nucleic acid analysis of biological specimens
US9867250B1 (en) 2015-04-20 2018-01-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence
WO2016193181A1 (en) * 2015-05-29 2016-12-08 Nanoimmunotech, S.L. Biosensors, kits and assays for measuring metalloproteinase and serine protease activities
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
US10399130B2 (en) 2015-07-22 2019-09-03 Arizona Board Of Regents On Behalf Of Arizona State University Methods and systems for in situ temporary containment of shallow contaminated soils
US11521475B1 (en) 2015-08-31 2022-12-06 Hitek Aqua Systems System for and method remotely monitoring chemistry of recreational water facilities
US20180263539A1 (en) * 2015-09-28 2018-09-20 The Regents Of The University Of California Wearable sensor arrays for in-situ body fluid analysis
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
US10386351B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using gas species diffusion
US10386365B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using ionic species diffusion
US11988662B2 (en) 2015-12-07 2024-05-21 Nanohmics, Inc. Methods for detecting and quantifying gas species analytes using differential gas species diffusion
WO2017106760A1 (en) 2015-12-16 2017-06-22 Siren Care, Inc. System and method for detecting inflammation in a foot
US10849600B2 (en) 2016-03-08 2020-12-01 Entech Instruments Inc. Breath condensate and saliva analysis using oral rinse
AU2017232651A1 (en) 2016-03-18 2018-10-04 ConnectedYard, Inc. Chemical monitoring devices and methods
US10190973B2 (en) * 2016-03-31 2019-01-29 Sensor Electronic Technology, Inc. Integrated ultraviolet analyzer
US10926025B2 (en) 2016-09-15 2021-02-23 Tandem Diabetes Care, Inc. Vial supporter for medicament pump
WO2018057883A1 (en) * 2016-09-22 2018-03-29 Src, Inc. Methods and systems for detection and tracking of mastitis in dairy cattle
EP3568174A4 (de) 2017-01-11 2020-07-29 Tandem Diabetes Care, Inc. Auf elektromagnetischem signal basierende infusionspumpensteuerung
RU175245U1 (ru) * 2017-01-13 2017-11-28 Сергей Викторович Минаев Сепарационное устройство для определения биохимических показателей и маркеров заболеваний в плазме крови
EP3577438B1 (de) * 2017-01-31 2025-02-26 Bahçesehir Üniversitesi Unterwasserlichtquelle
WO2018160757A1 (en) * 2017-02-28 2018-09-07 Entech Instruments Inc. Increasing the sensitivity of gas chromatography analysis by allowing relatively large solvent volume injections while reducing sample loss and system contamination
US10641733B2 (en) * 2017-03-20 2020-05-05 National Technology & Engineering Solutions Of Sandia, Llc Active mechanical-environmental-thermal MEMS device for nanoscale characterization
AU2018239360C1 (en) 2017-03-21 2023-11-02 Hayward Industries, Inc. Systems and methods for sanitizing pool and spa water
JP2020515871A (ja) 2017-03-21 2020-05-28 ミュウェルス,インコーポレイテッド 密封型マイクロウェルアッセイ
US10429303B2 (en) * 2017-03-24 2019-10-01 International Business Machines Corporation Portable and autonomous, IoT enabled, optical measurement system
GB201708339D0 (en) * 2017-05-24 2017-07-05 Univ Court Univ Of Glasgow Metabolite detection apparatus and method of detecting metabolites
US10684277B2 (en) * 2017-07-24 2020-06-16 Comsats Institute Of Information Technology Colorimetric filter paper assay for rapid monitoring of cholesterol level
CN107621455A (zh) * 2017-08-02 2018-01-23 广西中医药大学制药厂 壮药材藤苦参中总强心苷含量的测定方法
EP3669171A1 (de) * 2017-08-17 2020-06-24 Abbott Point of Care Inc. Einwegtestvorrichtung zur abbildung von blutzellen
EP3669179B1 (de) 2017-08-17 2023-07-19 Abbott Point Of Care Inc Systeme zur durchführung optischer und elektrochemischer analysen
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
WO2019035087A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. METHOD FOR IMAGING DOSING BALLS IN A BIOLOGICAL SAMPLE
WO2019035086A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. SINGLE-USE TEST DEVICE FOR THE IMAGING OF DOSING BALLS
US20190056304A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. Method of imaging blood cells
EP3460472B1 (de) * 2017-09-22 2024-09-18 Nokia Technologies Oy Funktionalisierte partikel
JP7359772B2 (ja) * 2017-11-01 2023-10-11 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 検体検出方法
US20210069706A1 (en) * 2017-12-12 2021-03-11 Trustees Of Boston University Disposable fluidic cartridge for interferometric reflectance imaging sensor
ES2956109T3 (es) * 2018-02-15 2023-12-13 Procisedx Inc Analizador
EP3742969B1 (de) 2018-03-06 2025-04-09 Entech Instruments Inc. Vorrichtung und verfahren für lüftergekoppelte probenentnahme
US11561221B2 (en) 2018-05-02 2023-01-24 Trustees Of Boston University Dynamic tracking of captured targets for enhanced digital biosensing
WO2020014296A1 (en) 2018-07-12 2020-01-16 Luminex Corporation Systems and methods for performing variable sample preparation and analysis processes
EP3593708B1 (de) 2018-07-13 2024-08-28 Nokia Technologies Oy Künstliche haut
JP7157869B2 (ja) 2018-07-31 2022-10-20 エンテック インスツルメンツ インコーポレイテッド ハイブリッドキャピラリ/充填トラップ及び使用方法
CN108956760A (zh) * 2018-08-01 2018-12-07 京东方科技集团股份有限公司 检测装置及检测系统
CN110819523B (zh) * 2018-08-13 2023-08-29 上海新微技术研发中心有限公司 一种数字pcr系统及数字pcr液滴形成方法
US11592427B2 (en) * 2018-10-01 2023-02-28 Brown University Multi-parametric machine olfaction
KR102145883B1 (ko) * 2018-12-17 2020-08-20 고려대학교 산학협력단 단일 입자 분석을 위한 다공성 막
US12233240B2 (en) 2018-12-26 2025-02-25 Tandem Diabetes Care, Inc. Methods of wireless communication in an infusion pump system
EP3906413A4 (de) * 2019-01-03 2022-11-16 Pixcell Medical Technologies Ltd. Systeme und verfahren zur analyse einer flüssigkeitsprobe
WO2020171838A1 (en) 2019-02-19 2020-08-27 Tandem Diabetes Care, Inc. System and method of pairing an infusion pump with a remote control device
AU2020201395B2 (en) * 2019-02-26 2025-06-05 Pentair Water Pool And Spa, Inc. Water quality monitor system and method
US20220073964A1 (en) * 2019-03-07 2022-03-10 Hewlett-Packard Development Company, L.P. Nucleic acid detection
DE102019106194B4 (de) * 2019-03-12 2020-12-03 Surflay Nanotec Gmbh Vorrichtung zur spektroskopischen Bestimmung der Bindungskinetik eines Analyten
US11305057B2 (en) 2019-03-26 2022-04-19 Tandem Diabetes Care, Inc. Method and system of operating an infusion pump with a remote control device
WO2020205418A1 (en) * 2019-03-29 2020-10-08 Polymer Technology Systems, Inc. Systems and methods for test strip insertion positioning check and type match
WO2020210981A1 (en) * 2019-04-16 2020-10-22 Boe Technology Group Co., Ltd. Micro-channel device and manufacturing method thereof and micro-fluidic system
US20220204531A1 (en) * 2019-06-04 2022-06-30 The Regents Of The University Of California Diboronic acid compounds and methods of making and using thereof
US20220276235A1 (en) * 2019-07-18 2022-09-01 Essenlix Corporation Imaging based homogeneous assay
KR102751768B1 (ko) * 2019-07-26 2025-01-07 엘지디스플레이 주식회사 형광 디스플레이 센서
RU2722604C1 (ru) * 2019-08-01 2020-06-02 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") Устройство для спектрального анализа
US11327084B2 (en) * 2019-09-19 2022-05-10 Invidx Corp. Joint hematology and biochemistry point-of-care testing system
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
WO2021119178A1 (en) 2019-12-10 2021-06-17 Lantha Inc. Probes for chemical analysis and related methods
AU2020404884A1 (en) 2019-12-17 2022-07-21 Lantha Inc. Mobile devices for chemical analysis and related methods
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
CN111229337B (zh) * 2020-01-17 2021-11-30 上海新微技术研发中心有限公司 光波导多微流道芯片的制造方法
US20210325380A1 (en) * 2020-04-20 2021-10-21 EnLiSense, LLC Disease diagnostics using a multi-configurable sensing array
EP4153984A1 (de) 2020-05-19 2023-03-29 10X Genomics, Inc. Elektrophoresekassetten und -instrumentierung
ES2989052T3 (es) 2020-05-22 2024-11-25 10X Genomics Inc Medición espacio-temporal simultánea de la expresión génica y la actividad celular
US20210379578A1 (en) * 2020-06-04 2021-12-09 Illumina, Inc. Apparatus with a sensor having an active surface
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
CN111924541B (zh) * 2020-07-01 2021-12-07 山东聊城华阳医药辅料有限公司 一种基于光敏电阻值特性的气动管道输送装置
US20220091031A1 (en) * 2020-09-18 2022-03-24 Salvus, Llc Interferometric Detection and Quantification System and Methods of Use in Chemical Processing
ES2993269T3 (en) 2020-09-18 2024-12-26 10X Genomics Inc Sample handling apparatus and image registration methods
US11740177B2 (en) 2020-09-18 2023-08-29 Salvus, Llc Interferometric detection and quantification system and methods of use in aquatics
US12399172B2 (en) 2020-09-18 2025-08-26 Salvus, Llc Interferometric detection and quantification system and methods of use in healthcare
US11994504B2 (en) 2020-09-18 2024-05-28 Salvus, Llc Interferometric detection and quantification system and methods of use in food processing and food supply chain
WO2022093212A1 (en) * 2020-10-28 2022-05-05 Hewlett-Packard Development Company, L.P. Self-wicking assay devices
WO2022108324A1 (ko) * 2020-11-18 2022-05-27 주식회사 엘지에너지솔루션 전극 건조 자동 제어 시스템 및 전극 건조 자동 제어 방법
EP4421491A3 (de) 2021-02-19 2024-11-27 10X Genomics, Inc. Verfahren zur verwendung einer modularen testträgervorrichtung
KR102808893B1 (ko) * 2021-02-19 2025-05-19 주식회사 히타치하이테크 플라스마 처리 장치
US20220365015A1 (en) * 2021-05-17 2022-11-17 Rhythmic Health, Inc. Mip sensor device with replaceable mip sensor
WO2022251538A1 (en) * 2021-05-27 2022-12-01 Siren Care, Inc. Sensor arrangements for a sensing garment
CN113358619B (zh) * 2021-06-05 2023-05-19 中国科学院新疆理化技术研究所 一种用于半定量检测高锰酸钾溶液的荧光传感分析卡制备方法及应用
CN113252862B (zh) * 2021-07-14 2021-09-17 四川久环环境技术有限责任公司 一种水质监测站
USD1064308S1 (en) 2021-09-17 2025-02-25 10X Genomics, Inc. Sample handling device
CN114015560B (zh) * 2021-10-20 2024-07-05 深圳市中科先见医疗科技有限公司 一种分子检测芯片
WO2023122033A1 (en) 2021-12-20 2023-06-29 10X Genomics, Inc. Self-test for pathology/histology slide imaging device
GB2623953A (en) * 2022-10-31 2024-05-08 Mighton Products Ltd Door lock assembly

Family Cites Families (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1114359A (en) * 1965-11-29 1968-05-22 Witco Chemical Corp Improvements in or relating to liquid detergent compositions
US3587040A (en) 1968-08-12 1971-06-22 Qonaar Corp Vehicle detector
US3696932A (en) 1970-09-30 1972-10-10 Pall Corp Disposable filter assembly
US3701433A (en) 1970-11-10 1972-10-31 Pall Corp Filter for use in the filtration of blood
US3709868A (en) 1971-03-08 1973-01-09 Hoffmann La Roche Opium alkaloid antigens and antibodies specific therefor
US3843696A (en) * 1972-09-05 1974-10-22 Syva Co Methadone analog compounds
US3775742A (en) 1972-09-18 1973-11-27 Canoga Controls Corp Vehicle detection system
CS164231B2 (de) * 1972-09-28 1975-11-07
US3856469A (en) 1973-01-02 1974-12-24 Syva Corp Interferant removal from amphetamine immunoassay
US3954623A (en) 1974-05-28 1976-05-04 Johnson & Johnson Blood filtration unit
US3876504A (en) * 1974-06-10 1975-04-08 Early Warning Co Procedure for determination of antigens and antibodies and articles for use therewith
US4189382A (en) 1974-11-07 1980-02-19 Sherwood Medical Industries Inc. Blood coagulation and separation
US4036946A (en) 1975-10-20 1977-07-19 Marcos Kleinerman Immunofluorometric method for measuring minute quantities of antigens, antibodies and other substances
US4050898A (en) * 1976-04-26 1977-09-27 Eastman Kodak Company Integral analytical element
US4069017A (en) * 1977-01-14 1978-01-17 Eastman Kodak Company Colorimetric assay for bilirubin
US4200613A (en) * 1977-06-03 1980-04-29 Ramco Laboratories Inc. Radioimmunoassay apparatus
US4115277A (en) 1977-06-17 1978-09-19 Pioneer Filters, Inc. Blood filtering apparatus of graduated fiber density
US4294817A (en) 1977-11-25 1981-10-13 International Diagnostic Technology, Inc. Method of fluoro immunoassay
US4245041A (en) 1977-12-07 1981-01-13 American Monitor Corporation Triglycerides assay and reagents therefor
US4246107A (en) 1978-03-06 1981-01-20 Asahi Kasei Kogyo Kabushiki Kaisha Separation of lymphocytes from lymphocyte-containing suspension by filtration
US4378429A (en) 1979-08-23 1983-03-29 Modrovich Ivan Endre Enzymatic method and stabilized solutions for determining total cholesterol in human serum
JPS5659802A (en) * 1979-10-23 1981-05-23 Shinroihi Kk Microspherical polymer particle and production thereof
US4344743A (en) 1979-12-04 1982-08-17 Bessman Samuel P Piezoelectric driven diaphragm micro-pump
DE3029579C2 (de) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4596657A (en) 1982-06-04 1986-06-24 Miles Laboratories, Inc. Blood bag system with integral filtering means
US4588665A (en) * 1982-11-22 1986-05-13 Drexler Technology Corporation Micrographic film member with laser written data
US4567149A (en) 1983-03-17 1986-01-28 Mast Immunosystems, Ltd. Binding assay system and method of making and using same
US4493815A (en) * 1983-07-28 1985-01-15 Bio-Rad Laboratories, Inc. Supporting and filtering biochemical test plate assembly
US4672028A (en) * 1984-05-23 1987-06-09 Icn Micromedic Systems, Inc. Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels
US4681742A (en) * 1984-10-01 1987-07-21 Cetus Corporation Assay tray
JPH0823558B2 (ja) * 1984-11-27 1996-03-06 オ−ジエニクス リミテツド 検定装置
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US5354825A (en) 1985-04-08 1994-10-11 Klainer Stanley M Surface-bound fluorescent polymers and related methods of synthesis and use
US4661445A (en) 1985-05-24 1987-04-28 Saxinger W Carl Competitive ELISA for the detection of HTLV-III antibodies
US4623461A (en) 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US5597531A (en) * 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US4855225A (en) 1986-02-07 1989-08-08 Applied Biosystems, Inc. Method of detecting electrophoretically separated oligonucleotides
US4810378A (en) 1986-04-21 1989-03-07 Miles Laboratories, Inc. Red blood cell filtering system
US5143853A (en) 1986-06-25 1992-09-01 Trustees Of Tufts College Absorbance modulated fluorescence detection methods and sensors
US5252494A (en) * 1986-06-25 1993-10-12 Trustees Of Tufts College Fiber optic sensors, apparatus, and detection methods using controlled release polymers and reagent formulations held within a polymeric reaction matrix
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4753776A (en) 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
CH672383A5 (de) 1986-10-29 1989-11-15 Baumer Electric Ag
US4925800A (en) 1986-12-04 1990-05-15 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibody against human pneumocystis carinii
US4813277A (en) * 1987-03-30 1989-03-21 Amoco Corporation Method for collecting magnetizable particles in an above ground storage tank
US4828386A (en) * 1987-06-19 1989-05-09 Pall Corporation Multiwell plates containing membrane inserts
US4988618A (en) * 1987-11-16 1991-01-29 Gene-Trak Systems Magnetic separation device and methods for use in heterogeneous assays
US5209904A (en) 1987-12-23 1993-05-11 Abbott Laboratories Agglutination reaction device utilizing selectively impregnated porous material
US4938742A (en) 1988-02-04 1990-07-03 Smits Johannes G Piezoelectric micropump with microvalves
US5162863A (en) 1988-02-15 1992-11-10 Canon Kabushiki Kaisha Method and apparatus for inspecting a specimen by optical detection of antibody/antigen sensitized carriers
DE68911359T2 (de) 1988-04-26 1994-05-11 Nippon Telegraph & Telephone Lasermagnetisches Immuntestverfahren und Gerät dazu.
US4874499A (en) 1988-05-23 1989-10-17 Massachusetts Institute Of Technology Electrochemical microsensors and method of making such sensors
US5252294A (en) * 1988-06-01 1993-10-12 Messerschmitt-Bolkow-Blohm Gmbh Micromechanical structure
US4908112A (en) 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
DE68926504T2 (de) 1988-07-20 1996-09-12 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
IT1226712B (it) 1988-08-05 1991-02-05 Eniricerche Spa Metodo immunoenzimatico elisa monopiastra con inibizione competitiva per la rivelazione di anticorpi antisporozoitari di plasmodium falciparum.
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
FR2638848B1 (fr) * 1988-11-04 1993-01-22 Chemunex Sa Procede de detection et/ou de dosage dans un milieu liquide ou semi-liquide d'au moins une substance organique, biologique ou medicamenteuse soluble, par une methode d'agglutination
IE67038B1 (en) 1988-12-22 1996-02-21 Patrick Joseph Joyce Immunodiagnostic assays for use in the detection and determination of mastitis
US6008031A (en) 1989-05-12 1999-12-28 Duke University Method of analysis and manipulation of DNA utilizing mismatch repair systems
US5156810A (en) 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5491097A (en) * 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5053197A (en) 1989-07-19 1991-10-01 Pb Diagnostic Systems, Inc. Diagnostic assay module
JP3127449B2 (ja) 1989-07-28 2001-01-22 三菱化学株式会社 抗体の測定法
US5698271A (en) 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
CA2024548C (en) 1989-09-05 2002-05-28 David Issachar Analyte specific chemical sensor
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5137833A (en) * 1989-09-21 1992-08-11 Russell Anthony P Method for detecting polyhydroxyl compounds
US5366860A (en) 1989-09-29 1994-11-22 Applied Biosystems, Inc. Spectrally resolvable rhodamine dyes for nucleic acid sequence determination
US5188934A (en) 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
US4997577A (en) 1989-12-20 1991-03-05 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
US5547682A (en) * 1989-12-22 1996-08-20 Bioquest, Incorporated Preparation and use of novel injectable RES avoiding inorganic particles for medical application
AU635105B2 (en) 1990-01-26 1993-03-11 Abbott Laboratories Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5183740A (en) 1990-02-23 1993-02-02 The United States Of America As Represented By The Secretary Of The Navy Flow immunosensor method and apparatus
US5182366A (en) 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
US5965695A (en) 1990-05-15 1999-10-12 Chiron Corporation Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
US5240640A (en) * 1990-06-04 1993-08-31 Coulter Corporation In situ use of gelatin or an aminodextran in the preparation of uniform ferrite particles
US5223393A (en) * 1990-06-12 1993-06-29 Microgenics Corporation Detection of analytes having binding sites for at least two binding moieties
WO1992000880A1 (en) 1990-07-09 1992-01-23 S.C.I. Operations Pty Limited Trading As Smorgon Plastics An improved container
US5147606A (en) 1990-08-06 1992-09-15 Miles Inc. Self-metering fluid analysis device
US5071076A (en) 1990-08-10 1991-12-10 Omni Quest Corporation Method for producing magnetic microparticles from metallocenes
US5235028A (en) 1990-08-31 1993-08-10 University Of Minnesota Polyethylene glycol derivatives for solid-phase applications
US5244636A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5250264A (en) * 1991-01-25 1993-10-05 Trustees Of Tufts College Method of making imaging fiber optic sensors to concurrently detect multiple analytes of interest in a fluid sample
US5244813A (en) * 1991-01-25 1993-09-14 Trustees Of Tufts College Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample
US5235039A (en) 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease
US5578444A (en) 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
AU2348092A (en) 1991-07-16 1993-02-23 Transmed Biotech Incorporated Methods and compositions for simultaneous analysis of multiple analytes
US5837552A (en) * 1991-07-22 1998-11-17 Medifor, Ltd. Surface-enhanced analytical procedures and substrates
US5211850A (en) 1991-07-26 1993-05-18 Research Medical, Inc. Plasma filter sorbent system for removal of components from blood
US5288214A (en) 1991-09-30 1994-02-22 Toshio Fukuda Micropump
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
EP0916396B1 (de) * 1991-11-22 2005-04-13 Affymetrix, Inc. (a Delaware Corporation) Kombinatorische Strategien für die Polymersynthese
JPH05157684A (ja) 1991-12-02 1993-06-25 Seikagaku Kogyo Co Ltd 吸光光度計
US6063581A (en) * 1992-01-22 2000-05-16 Axis-Shield Asa Immunoassay for homocysteine
US5262127A (en) * 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
US5654497A (en) 1992-03-03 1997-08-05 Lockheed Martin Energy Systems, Inc. Motor vehicle fuel analyzer
US5391272A (en) 1992-03-06 1995-02-21 Andcare, Inc. Electrochemical immunoassay methods
US5518887A (en) 1992-03-30 1996-05-21 Abbott Laboratories Immunoassays empolying generic anti-hapten antibodies and materials for use therein
US5248742A (en) 1992-04-27 1993-09-28 Gencorp Inc. Unsaturated polyester-epoxy resin network composition
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US5296375A (en) * 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5278303A (en) * 1992-06-12 1994-01-11 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
US5674698A (en) * 1992-09-14 1997-10-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
JPH08507148A (ja) 1993-02-17 1996-07-30 カーディオヴァスキュラー ダイアグノスティクス,インク. 固相化学カスケードイムノアッセイおよびアフィニティアッセイ
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5677196A (en) 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
GB9311988D0 (en) 1993-06-10 1993-07-28 Pall Corp Device and method for separating plasma from a blood product
US6087186A (en) * 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US5382512A (en) 1993-08-23 1995-01-17 Chiron Corporation Assay device with captured particle reagent
FR2710410B1 (fr) * 1993-09-20 1995-10-20 Bio Merieux Procédé et dispositif pour la détermination d'un analyte dans un échantillon .
US5472672A (en) * 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
CA2174140C (en) * 1993-10-28 2004-04-06 Kenneth L. Beattie Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US5499909A (en) 1993-11-17 1996-03-19 Aisin Seiki Kabushiki Kaisha Of Kariya Pneumatically driven micro-pump
US5759015A (en) 1993-12-28 1998-06-02 Westonbridge International Limited Piezoelectric micropump having actuation electrodes and stopper members
US5616698A (en) 1994-01-10 1997-04-01 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
US5631130A (en) 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
DE69527585T2 (de) * 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
JPH0842457A (ja) 1994-07-27 1996-02-13 Aisin Seiki Co Ltd マイクロポンプ
US5512490A (en) 1994-08-11 1996-04-30 Trustees Of Tufts College Optical sensor, optical sensing apparatus, and methods for detecting an analyte of interest using spectral recognition patterns
US5965590A (en) * 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
AUPM807094A0 (en) * 1994-09-09 1994-10-06 Commonwealth Scientific And Industrial Research Organisation Polymer beads and method for preparation thereof
US5632876A (en) 1995-06-06 1997-05-27 David Sarnoff Research Center, Inc. Apparatus and methods for controlling fluid flow in microchannels
US5846396A (en) 1994-11-10 1998-12-08 Sarnoff Corporation Liquid distribution system
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5603351A (en) * 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5616790A (en) * 1994-11-18 1997-04-01 California Institute Of Technology Lipid-based metal sensor
US5550373A (en) * 1994-12-30 1996-08-27 Honeywell Inc. Fabry-Perot micro filter-detector
US5571401A (en) 1995-03-27 1996-11-05 California Institute Of Technology Sensor arrays for detecting analytes in fluids
GB2300258A (en) 1995-04-28 1996-10-30 Philip John Jewess A separation device for magnetisable particles
US5834318A (en) 1995-05-10 1998-11-10 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
US6524532B1 (en) * 1995-06-20 2003-02-25 The Regents Of The University Of California Microfabricated sleeve devices for chemical reactions
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6168948B1 (en) * 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US5690807A (en) * 1995-08-03 1997-11-25 Massachusetts Institute Of Technology Method for producing semiconductor particles
US5843655A (en) 1995-09-18 1998-12-01 Affymetrix, Inc. Methods for testing oligonucleotide arrays
US5863975A (en) 1995-10-03 1999-01-26 Rheox Inc. Aqueous construction compositions with improved water retention properties and a process for providing water retention properties to aqueous construction compositions
US5714122A (en) * 1995-11-22 1998-02-03 Minnesota Mining And Manufacturing Company Emulsion for robust sensing
US5705018A (en) * 1995-12-13 1998-01-06 Hartley; Frank T. Micromachined peristaltic pump
US5814524A (en) * 1995-12-14 1998-09-29 Trustees Of Tufts College Optical sensor apparatus for far-field viewing and making optical analytical measurements at remote locations
WO1997025437A1 (en) * 1996-01-04 1997-07-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for assaying proteolytic enzymes using fluorescence-quenched substrates
JP3664328B2 (ja) 1996-01-19 2005-06-22 富士写真フイルム株式会社 血漿または血清試料の調製方法
US6013440A (en) 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
US5747349A (en) 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US5788814A (en) * 1996-04-09 1998-08-04 David Sarnoff Research Center Chucks and methods for positioning multiple objects on a substrate
US5840256A (en) 1996-04-09 1998-11-24 David Sarnoff Research Center Inc. Plate for reaction system
US5879632A (en) * 1996-04-09 1999-03-09 Sarnoff Corporation Apportioning system
JPH09281045A (ja) * 1996-04-10 1997-10-31 Kdk Corp メバロン酸の光学的測定方法
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
JP3950493B2 (ja) * 1996-04-26 2007-08-01 東レ・ダウコーニング株式会社 導電性シリコーンゴム組成物、半導体装置の製造方法およびその半導体装置
FR2749082B1 (fr) * 1996-05-24 1998-06-26 Bio Merieux Particules superparamagnetiques et monodispersees
US6103479A (en) * 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
US5770370A (en) * 1996-06-14 1998-06-23 David Sarnoff Research Center, Inc. Nuclease protection assays
US5797898A (en) 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
GB2315131B (en) 1996-07-10 2000-11-29 Cambridge Imaging Ltd Improvements in and relating to imaging
US5707502A (en) 1996-07-12 1998-01-13 Chiron Diagnostics Corporation Sensors for measuring analyte concentrations and methods of making same
US5872623A (en) * 1996-09-26 1999-02-16 Sarnoff Corporation Massively parallel detection
US5854684A (en) * 1996-09-26 1998-12-29 Sarnoff Corporation Massively parallel detection
US5861658A (en) 1996-10-03 1999-01-19 International Business Machines Corporation Inorganic seal for encapsulation of an organic layer and method for making the same
US5748091A (en) * 1996-10-04 1998-05-05 Mcdonnell Douglas Corporation Fiber optic ice detector
US6048732A (en) 1996-10-16 2000-04-11 Board Of Regents, The University Of Texas System Receptor and method for citrate determination
JP2001504389A (ja) 1996-10-21 2001-04-03 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ビーズを分配する装置と方法
US6083761A (en) * 1996-12-02 2000-07-04 Glaxo Wellcome Inc. Method and apparatus for transferring and combining reagents
US5779907A (en) * 1996-12-06 1998-07-14 Systems Research Laboratories, Inc. Magnetic microplate separator
US6245331B1 (en) * 1997-01-02 2001-06-12 New York Univ. Medical Center Early detection of mycobacterial disease
WO1998029736A1 (en) * 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
US6413786B1 (en) * 1997-01-23 2002-07-02 Union Biometrica Technology Holdings, Inc. Binding assays using optical resonance of colloidal particles
US5827748A (en) * 1997-01-24 1998-10-27 The United States Of America As Represented By The Secretary Of The Navy Chemical sensor using two-dimensional lens array
US5981297A (en) 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US6037137A (en) 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6045579A (en) * 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
US6406845B1 (en) * 1997-05-05 2002-06-18 Trustees Of Tuft College Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
US6171780B1 (en) * 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6426050B1 (en) * 1997-05-16 2002-07-30 Aurora Biosciences Corporation Multi-well platforms, caddies, lids and combinations thereof
JP4294740B2 (ja) 1997-05-23 2009-07-15 ソレクサ・インコーポレイテッド 分析物の系列的プロセシングのためのシステムおよび装置
US5985120A (en) * 1997-06-12 1999-11-16 University Of Massachusetts Rapid analysis of analyte solutions
US6002817A (en) 1997-09-29 1999-12-14 The Regents Of The University Of Michigan Optical sensors for the detection of nitric oxide
US7115884B1 (en) 1997-10-06 2006-10-03 Trustees Of Tufts College Self-encoding fiber optic sensor
US5922617A (en) * 1997-11-12 1999-07-13 Functional Genetics, Inc. Rapid screening assay methods and devices
US5992820A (en) 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
US6074616A (en) * 1998-01-05 2000-06-13 Biosite Diagnostics, Inc. Media carrier for an assay device
AU2464299A (en) * 1998-01-22 1999-08-09 Luminex Corporation Microparticles with multiple fluorescent signals
US6210910B1 (en) * 1998-03-02 2001-04-03 Trustees Of Tufts College Optical fiber biosensor array comprising cell populations confined to microcavities
JP3944996B2 (ja) 1998-03-05 2007-07-18 株式会社日立製作所 Dnaプローブアレー
JP3459770B2 (ja) * 1998-04-10 2003-10-27 キヤノン株式会社 画像読取装置および方法、記録媒体
DE19827754C1 (de) 1998-06-23 2000-02-10 Graffinity Pharm Design Gmbh Einrichtung für eine nahezu gleichzeitige Synthese einer Vielzahl von Proben
DE19825909C1 (de) * 1998-06-10 1999-11-25 Graffinity Pharm Design Gmbh Reaktorträger mit mehreren Mikroprobenaufnahmekammern
US6692696B1 (en) * 1998-06-18 2004-02-17 ARETé ASSOCIATES Biosensor
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
GB9821573D0 (en) 1998-10-02 1998-11-25 Central Research Lab Ltd Method and apparatus for removing a substance from a container
US6601613B2 (en) * 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6136273A (en) * 1998-11-18 2000-10-24 Matrix Technologies Corporation Closure device for laboratory receptacles
US6151973A (en) * 1999-01-29 2000-11-28 Glaxo Wellcome Inc. Bead picking apparatus and method
US6787368B1 (en) * 1999-03-02 2004-09-07 Helix Biopharma Corporation Biosensor method for detecting analytes in a liquid
CN1185492C (zh) * 1999-03-15 2005-01-19 清华大学 可单点选通式微电磁单元阵列芯片、电磁生物芯片及应用
US6355431B1 (en) * 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US6258229B1 (en) * 1999-06-02 2001-07-10 Handani Winarta Disposable sub-microliter volume sensor and method of making
US6219566B1 (en) * 1999-07-13 2001-04-17 Photonics Research Ontario Method of measuring concentration of luminescent materials in turbid media
US6589779B1 (en) * 1999-07-16 2003-07-08 Board Of Regents, The University Of Texas System General signaling protocol for chemical receptors in immobilized matrices
US7022517B1 (en) * 1999-07-16 2006-04-04 Board Of Regents, The University Of Texas System Method and apparatus for the delivery of samples to a chemical sensor array
US6411207B2 (en) * 1999-10-01 2002-06-25 Avaya Technology Corp. Personal alert device
US6682649B1 (en) * 1999-10-01 2004-01-27 Sophion Bioscience A/S Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
US6254830B1 (en) * 1999-11-05 2001-07-03 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Magnetic focusing immunosensor for the detection of pathogens
US6309889B1 (en) * 1999-12-23 2001-10-30 Glaxo Wellcome Inc. Nano-grid micro reactor and methods
DE60135092D1 (de) * 2000-01-31 2008-09-11 Univ Texas Tragbare vorrichtung mit einer sensor-array-anordnung
US6514415B2 (en) * 2000-01-31 2003-02-04 Dexter Magnetic Technologies, Inc. Method and apparatus for magnetic separation of particles
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
EP1502097A2 (de) * 2002-04-26 2005-02-02 Board of Regents, The University of Texas System Verfahren und system zur detektion von kardialen risikofaktoren
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
WO2007005666A2 (en) * 2005-07-01 2007-01-11 Board Of Regents, The University Of Texas System System and method of analyte detection using differential receptors

Also Published As

Publication number Publication date
EP1255980B1 (de) 2008-07-30
US6713298B2 (en) 2004-03-30
US20050136548A1 (en) 2005-06-23
US7316899B2 (en) 2008-01-08
CA2401782A1 (en) 2001-08-02
US6649403B1 (en) 2003-11-18
WO2001055952A9 (en) 2002-01-10
US20040053322A1 (en) 2004-03-18
US20030064422A1 (en) 2003-04-03
WO2001055701A9 (en) 2002-10-31
AU2001236597A1 (en) 2001-08-07
WO2001055952A2 (en) 2001-08-02
WO2001055704A8 (en) 2001-12-06
AU2001234709A1 (en) 2001-08-07
US20020045272A1 (en) 2002-04-18
EP1255980A1 (de) 2002-11-13
US20030186228A1 (en) 2003-10-02
WO2001055952A8 (en) 2002-05-16
WO2001055703A1 (en) 2001-08-02
AU2001247195A1 (en) 2001-08-07
WO2001055704A1 (en) 2001-08-02
DE60135092D1 (de) 2008-09-11
WO2001055703A9 (en) 2002-10-24
WO2001055702A1 (en) 2001-08-02
WO2001055701A1 (en) 2001-08-02
WO2001055702A9 (en) 2002-10-24
US20080219891A1 (en) 2008-09-11
US20110251075A1 (en) 2011-10-13
EP2230314A1 (de) 2010-09-22
AU2001233200A1 (en) 2001-08-07
AU2001238011A1 (en) 2001-08-07

Similar Documents

Publication Publication Date Title
ATE403145T1 (de) Tragbare vorrichtung mit einer sensor-array- anordnung
WO2004051219A3 (en) Nanotube chemical sensor based on work function of electrodes
BR9811502B1 (pt) sensor de pressão, sistema de medição de pressão e método para medir a pressão aplicada ao sensor.
DE60128110D1 (de) Quartzkristall Sensorzelle
FI20041536A7 (fi) Vaihdettavan kannen sisältävä kannettava laite
WO2004057314A3 (en) Polarisation interferometric method and sensor for detecting a chemical substance
WO2003062445A3 (en) Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for pcr analysis
WO2002103371A3 (en) Magnetic-based placement and retention of sensor elements in a sensor array
WO2002068932A3 (en) Methods for providing extended dynamic range in analyte assays
WO2007024763A3 (en) Industrial field device with automatic indication of solids
WO2001036966A3 (en) An apparatus for machine fluid analysis
AU4868901A (en) Flow sensor
ATE316651T1 (de) Biosensor
AU2001250883A1 (en) Method for detecting an analyte by fluorescence
CA2417913A1 (en) System for monitoring and testing of light sources
WO2005010480A3 (en) Sensor device utilizing carbon nanotubes
ATE549777T1 (de) Mess- und übertragungssystem mit einem steckverbindungssystem
TW200615513A (en) Mach Zehnder photonic crystal sensors and methods
PT1253412E (pt) Sistema de medicao da pressao
ATE371867T1 (de) Überwachung von zellen
ATE302159T1 (de) Flurförderzeug mit einer vorrichtung zum erfassen der hubhöhe
EP1503191A4 (de) Modellbenutzungs-lichtempfangseinrichtung, modell und modellbenutzungs-signallichtdetektionsverfahren
ATE321993T1 (de) Vorrichtung zur messung einer kraft- oder momentenkomponente
NO20023512L (no) Akustisk sensormodul, samt fremstillingsprosess for slik modul
DE59701589D1 (de) Linearantrieb mit einem magnetostriktiven Kraftsensor

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties