ITTO20020808A1 - Dispositivo integrato di analisi del dna. - Google Patents

Dispositivo integrato di analisi del dna.

Info

Publication number
ITTO20020808A1
ITTO20020808A1 IT000808A ITTO20020808A ITTO20020808A1 IT TO20020808 A1 ITTO20020808 A1 IT TO20020808A1 IT 000808 A IT000808 A IT 000808A IT TO20020808 A ITTO20020808 A IT TO20020808A IT TO20020808 A1 ITTO20020808 A1 IT TO20020808A1
Authority
IT
Italy
Prior art keywords
analysis device
dna analysis
integrated dna
integrated
dna
Prior art date
Application number
IT000808A
Other languages
English (en)
Inventor
Ubaldo Mastromatteo
Michele Palmieri
Mario Scurati
Original Assignee
St Microelectronics Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Microelectronics Srl filed Critical St Microelectronics Srl
Priority to IT000808A priority Critical patent/ITTO20020808A1/it
Priority to US10/663,286 priority patent/US20040132059A1/en
Priority to EP03103421A priority patent/EP1400600A1/en
Publication of ITTO20020808A1 publication Critical patent/ITTO20020808A1/it
Priority to US11/092,415 priority patent/US20050233440A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02Separators
    • B03C5/022Non-uniform field separators
    • B03C5/026Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0424Dielectrophoretic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Biochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IT000808A 2002-09-17 2002-09-17 Dispositivo integrato di analisi del dna. ITTO20020808A1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT000808A ITTO20020808A1 (it) 2002-09-17 2002-09-17 Dispositivo integrato di analisi del dna.
US10/663,286 US20040132059A1 (en) 2002-09-17 2003-09-16 Integrated device for biological analyses
EP03103421A EP1400600A1 (en) 2002-09-17 2003-09-17 Integrated device for biological analyses
US11/092,415 US20050233440A1 (en) 2002-09-17 2005-03-29 Apparatus for biochemical analysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000808A ITTO20020808A1 (it) 2002-09-17 2002-09-17 Dispositivo integrato di analisi del dna.

Publications (1)

Publication Number Publication Date
ITTO20020808A1 true ITTO20020808A1 (it) 2004-03-18

Family

ID=31898514

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000808A ITTO20020808A1 (it) 2002-09-17 2002-09-17 Dispositivo integrato di analisi del dna.

Country Status (3)

Country Link
US (2) US20040132059A1 (it)
EP (1) EP1400600A1 (it)
IT (1) ITTO20020808A1 (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7230315B2 (en) 2000-02-29 2007-06-12 Stmicroelectronics S.R.L. Integrated chemical microreactor with large area channels and manufacturing process thereof

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7732192B2 (en) * 2000-02-29 2010-06-08 Stmicroelectronics S.R.L. Integrated chemical microreactor with large area channels and manufacturing process thereof
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
ITTO20020808A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Dispositivo integrato di analisi del dna.
US7731906B2 (en) 2003-07-31 2010-06-08 Handylab, Inc. Processing particle-containing samples
EP1535665A1 (en) 2003-11-28 2005-06-01 STMicroelectronics S.r.l. Integrated chemical microreactor with separated channels for confining liquids inside the channels and manufacturing process thereof
US7767439B2 (en) * 2003-12-10 2010-08-03 Samsung Electronics Co., Ltd. Real-time PCR monitoring apparatus and method
EP1541991A1 (en) * 2003-12-12 2005-06-15 STMicroelectronics S.r.l. Integrated semiconductor chemical microreactor for real-time monitoring of biological reactions
US20050161327A1 (en) * 2003-12-23 2005-07-28 Michele Palmieri Microfluidic device and method for transporting electrically charged substances through a microchannel of a microfluidic device
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
WO2006085948A2 (en) * 2004-07-01 2006-08-17 Cornell Research Foundation, Inc. Real-time pcr detection of microorganisms using an integrated microfluidics platform
US7832429B2 (en) * 2004-10-13 2010-11-16 Rheonix, Inc. Microfluidic pump and valve structures and fabrication methods
EP1885646A1 (en) * 2005-05-12 2008-02-13 STMicroelectronics S.r.l. Microfluidic device with integrated micropump, in particular biochemical microreactor, and manufacturing method thereof
ITBO20050643A1 (it) * 2005-10-24 2007-04-25 Si Bio S R L Metodo ed apparato per la manipolazione di particelle in soluzioni conduttive
EP1951860A4 (en) * 2005-11-21 2012-06-06 Life Technologies Corp PORTABLE PREPARATION, ANALYSIS AND DETECTION APPARATUS FOR THE TREATMENT OF NUCLEIC ACIDS
DE102005059536B4 (de) * 2005-12-13 2008-08-28 Siemens Ag Verfahren und Biochip zur Untersuchung einer biologischen Probe
WO2007091281A1 (en) * 2006-02-06 2007-08-16 Stmicroelectronics S.R.L. Nucleic acid analysis chip integrating a waveguide and optical apparatus for the inspection of nucleic acid probes
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
EP2001990B1 (en) 2006-03-24 2016-06-29 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
DE602006018206D1 (de) * 2006-06-23 2010-12-23 St Microelectronics Srl Anordnung einer mikrofluidvorrichtung zur analyse von biologischem material
EP2091647A2 (en) 2006-11-14 2009-08-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
EP2011574A1 (en) * 2007-07-02 2009-01-07 STMicroelectronics (Research & Development) Limited Assaying device and method of transporting a fluid in an assaying device
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
JP5651011B2 (ja) 2007-07-13 2015-01-07 ハンディーラブ インコーポレイテッド ポリヌクレオチド捕捉材料およびその使用方法
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
WO2009049268A1 (en) 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
US20110081367A1 (en) 2008-06-14 2011-04-07 Veredus Laboratories Pte Ltd Influenza sequences
US20090325159A1 (en) * 2008-06-30 2009-12-31 Canon U.S. Life Sciences, Inc. System and method to prevent cross-contamination in assays performed in a microfluidic channel
GB0812680D0 (en) * 2008-07-10 2008-08-20 Sec Dep For Innovation Univers Fluid decontamination method and apparatus
CH699853A1 (de) * 2008-11-13 2010-05-14 Tecan Trading Ag Messgerät und Verfahren zum Bestimmen von durch ein Laborsystem bereitgestellten Fluidparametern.
WO2010072790A1 (en) * 2008-12-23 2010-07-01 Stmicroelectronics S.R.L. Method for detecting the presence of liquids in a microfluidic device, detecting apparatus and corresponding microfluidic device
US8435454B2 (en) * 2009-07-09 2013-05-07 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US8273300B2 (en) * 2009-07-09 2012-09-25 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
KR101197607B1 (ko) * 2010-01-28 2012-11-08 (주)바이오메드랩 소형 dna 증폭 및 검사 장치
US8499613B2 (en) * 2010-01-29 2013-08-06 Stmicroelectronics S.R.L. Integrated chemical sensor for detecting odorous matters
EP2565616B1 (en) * 2010-04-28 2020-08-05 Panasonic Intellectual Property Management Co., Ltd. Chemical sensor
US9103787B2 (en) 2010-05-25 2015-08-11 Stmicroelectronics S.R.L. Optically accessible microfluidic diagnostic device
WO2011156849A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Test module with microfluidic device having loc and dialysis device for separating pathogens from other constituents in a biological sample
US9180451B2 (en) 2010-06-28 2015-11-10 Stmicroelectronics S.R.L. Fluidic cartridge for detecting chemicals in samples, in particular for performing biochemical analyses
BR112013026451B1 (pt) 2011-04-15 2021-02-09 Becton, Dickinson And Company sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação
WO2012154306A1 (en) 2011-05-12 2012-11-15 William Marsh Rice University Bio-nano-chips for on-site drug screening
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
CN103959070B (zh) 2011-09-30 2017-05-10 贝克顿·迪金森公司 组合试剂条
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
CA2863637C (en) 2012-02-03 2021-10-26 Becton, Dickinson And Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
GB201217390D0 (en) 2012-09-28 2012-11-14 Agplus Diagnostics Ltd Test device and sample carrier
AU2013334189B2 (en) 2012-10-24 2018-08-02 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) * 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US9222623B2 (en) 2013-03-15 2015-12-29 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
WO2015103326A1 (en) * 2013-12-31 2015-07-09 Canon U.S. Life Sciences, Inc. Field deployable small format fast first result microfluidic system
US10196678B2 (en) 2014-10-06 2019-02-05 ALVEO Technologies Inc. System and method for detection of nucleic acids
US9921182B2 (en) 2014-10-06 2018-03-20 ALVEO Technologies Inc. System and method for detection of mercury
US10352899B2 (en) 2014-10-06 2019-07-16 ALVEO Technologies Inc. System and method for detection of silver
US9506908B2 (en) 2014-10-06 2016-11-29 Alveo Technologies, Inc. System for detection of analytes
US10627358B2 (en) 2014-10-06 2020-04-21 Alveo Technologies, Inc. Method for detection of analytes
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
WO2016083550A1 (en) * 2014-11-26 2016-06-02 Imec Vzw Compact glass-based fluid analysis device and method to fabricate
US11371091B2 (en) 2015-06-22 2022-06-28 Fluxergy, Inc. Device for analyzing a fluid sample and use of test card with same
WO2016209731A1 (en) 2015-06-22 2016-12-29 Fluxergy, Llc Test card for assay and method of manufacturing same
US10519493B2 (en) 2015-06-22 2019-12-31 Fluxergy, Llc Apparatus and method for image analysis of a fluid sample undergoing a polymerase chain reaction (PCR)
WO2018057647A1 (en) * 2016-09-23 2018-03-29 Alveo Technologies, Inc. Methods and compositions for detecting analytes
EP3560593B1 (en) * 2018-04-25 2024-06-05 OPTOLANE Technologies Inc. Cartridge for digital real-time pcr
EP3852927B1 (en) * 2018-09-20 2025-06-25 Cepheid System, device and methods of sample processing using semiconductor detection chips
CA3123229A1 (en) 2018-12-14 2020-06-18 Cepheid Diagnostic detection chip devices and methods of manufacture and assembly
EP3899022A4 (en) 2018-12-20 2023-03-01 Alveo Technologies Inc. PORTABLE IMPEDANCE-BASED DIAGNOSTIC TEST SYSTEM FOR DETECTING ANALYTES
TWI709993B (zh) * 2019-06-18 2020-11-11 閎康科技股份有限公司 樣本承載裝置及其操作方法
US20210379578A1 (en) * 2020-06-04 2021-12-09 Illumina, Inc. Apparatus with a sensor having an active surface
CN115990526A (zh) * 2023-03-23 2023-04-21 浙江扬清芯片技术有限公司 一种高集成度的微流控实验平台

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4993143A (en) * 1989-03-06 1991-02-19 Delco Electronics Corporation Method of making a semiconductive structure useful as a pressure sensor
US6051380A (en) * 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5429734A (en) * 1993-10-12 1995-07-04 Massachusetts Institute Of Technology Monolithic capillary electrophoretic device
US6309602B1 (en) * 1993-11-01 2001-10-30 Nanogen, Inc. Stacked, reconfigurable system for electrophoretic transport of charged materials
SE9304145D0 (sv) * 1993-12-10 1993-12-10 Pharmacia Lkb Biotech Sätt att tillverka hålrumsstrukturer
US6403367B1 (en) * 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
DE19519015C1 (de) * 1995-05-24 1996-09-05 Inst Physikalische Hochtech Ev Miniaturisierter Mehrkammer-Thermocycler
US6168948B1 (en) * 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US20020022261A1 (en) * 1995-06-29 2002-02-21 Anderson Rolfe C. Miniaturized genetic analysis systems and methods
US5849208A (en) * 1995-09-07 1998-12-15 Microfab Technoologies, Inc. Making apparatus for conducting biochemical analyses
US20020068357A1 (en) * 1995-09-28 2002-06-06 Mathies Richard A. Miniaturized integrated nucleic acid processing and analysis device and method
WO1997025531A1 (en) * 1996-01-05 1997-07-17 Berkeley Microinstruments, Inc. Micropump with sonic energy generator
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
NZ333346A (en) * 1996-06-28 2000-03-27 Caliper Techn Corp High-throughput screening assay systems in microscale fluidic devices
US6031286A (en) * 1997-02-28 2000-02-29 International Business Machines Corporation Semiconductor structures containing a micro pipe system therein
US6116863A (en) * 1997-05-30 2000-09-12 University Of Cincinnati Electromagnetically driven microactuated device and method of making the same
US6093330A (en) * 1997-06-02 2000-07-25 Cornell Research Foundation, Inc. Microfabrication process for enclosed microstructures
US6440725B1 (en) * 1997-12-24 2002-08-27 Cepheid Integrated fluid manipulation cartridge
US6012902A (en) * 1997-09-25 2000-01-11 Caliper Technologies Corp. Micropump
US6887693B2 (en) * 1998-12-24 2005-05-03 Cepheid Device and method for lysing cells, spores, or microorganisms
US6261431B1 (en) * 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
US6283718B1 (en) * 1999-01-28 2001-09-04 John Hopkins University Bubble based micropump
US6238868B1 (en) * 1999-04-12 2001-05-29 Nanogen/Becton Dickinson Partnership Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
DE69935495T2 (de) * 1999-04-29 2007-11-29 Stmicroelectronics S.R.L., Agrate Brianza Herstellungsverfahren für vergrabene Kanäle und Hohlräume in Halbleiterscheiben
US20030064422A1 (en) * 2000-01-31 2003-04-03 Mcdevitt John T. Method and system for collecting and transmitting chemical information
DE60023464T2 (de) * 2000-06-05 2006-07-20 Stmicroelectronics S.R.L., Agrate Brianza Verfahren zur Herstellung integrierter chemischer Mikroreaktoren aus Halbleitermaterial sowie integrierter Mikroreaktor
DE60034562T2 (de) * 2000-08-25 2008-01-17 Stmicroelectronics S.R.L., Agrate Brianza Ein System zur automatischen Bildanalyse von DNA Mikroarrays
EP1193214B1 (en) * 2000-09-27 2007-01-03 STMicroelectronics S.r.l. Integrated chemical microreactor, thermally insulated from detection electrodes, and manufacturing method therefor
US6653124B1 (en) * 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
US6521188B1 (en) * 2000-11-22 2003-02-18 Industrial Technology Research Institute Microfluidic actuator
US6453928B1 (en) * 2001-01-08 2002-09-24 Nanolab Ltd. Apparatus, and method for propelling fluids
US6752601B2 (en) * 2001-04-06 2004-06-22 Ngk Insulators, Ltd. Micropump
US6727479B2 (en) * 2001-04-23 2004-04-27 Stmicroelectronics S.R.L. Integrated device based upon semiconductor technology, in particular chemical microreactor
ITTO20020808A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Dispositivo integrato di analisi del dna.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7230315B2 (en) 2000-02-29 2007-06-12 Stmicroelectronics S.R.L. Integrated chemical microreactor with large area channels and manufacturing process thereof

Also Published As

Publication number Publication date
EP1400600A1 (en) 2004-03-24
US20050233440A1 (en) 2005-10-20
US20040132059A1 (en) 2004-07-08

Similar Documents

Publication Publication Date Title
ITTO20020808A1 (it) Dispositivo integrato di analisi del dna.
DE602004024068D1 (de) Bedingungsanalyseeinrichtung
NO20053993D0 (no) Kjemiske forbindelser.
ITTO20030836A1 (it) Dispositivo di allineamento.
ITTO20020809A1 (it) Micropompa, in particolare per un dispositivo integrato di analisi del dna.
DE602004026370D1 (de) Bearbeitungsvorrichtung
ITTO20020033A0 (it) Dispositivo elettro-luminescente.
BR0318430B1 (pt) dispositivo de aperto.
FI20030261A0 (fi) Iskulaite
NL1025921A1 (nl) Apparaatbeker.
DE502004000507D1 (de) Spanneinrichtung
BR0318042B1 (pt) aparelho de identificaÇço.
ITMI20030502A1 (it) Dispositivo di stiratura.
NL1026663A1 (nl) Aandrijf-inrichting.
ITMN20030024A1 (it) Dispositivo per la raccolta di rifiuti.
ITAN20020024A1 (it) Dispositivo di aspirazione per w.c.
ES1055419Y (es) Dispositivo de diatermia capacitiva.
ES1053739Y (es) Dispositivo de soporte multiple.
ITTO20030081A1 (it) Dispositivo di misura.
ITTO20020264A0 (it) Dispositivo acquastop perfezionato.
ITFI20020216A1 (it) Dispositivo per prelievi agobioptici.
ITFI20020217A1 (it) Dispositivo per prelievi agobioptici.
NL1022805A1 (nl) Kleminrichting.
ITRI20030009A1 (it) Dispositivo portatile per dialisi extracorporea.
ES1055979Y (es) Dispositivo sujeta-pales.