DE602006018206D1 - Anordnung einer mikrofluidvorrichtung zur analyse von biologischem material - Google Patents

Anordnung einer mikrofluidvorrichtung zur analyse von biologischem material

Info

Publication number
DE602006018206D1
DE602006018206D1 DE602006018206T DE602006018206T DE602006018206D1 DE 602006018206 D1 DE602006018206 D1 DE 602006018206D1 DE 602006018206 T DE602006018206 T DE 602006018206T DE 602006018206 T DE602006018206 T DE 602006018206T DE 602006018206 D1 DE602006018206 D1 DE 602006018206D1
Authority
DE
Germany
Prior art keywords
analysis
arrangement
biological material
microfluid device
microfluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018206T
Other languages
English (en)
Inventor
Pierangelo Magni
Roberto Brioschi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STMicroelectronics SRL
Original Assignee
STMicroelectronics SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by STMicroelectronics SRL filed Critical STMicroelectronics SRL
Publication of DE602006018206D1 publication Critical patent/DE602006018206D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0638—Valves, specific forms thereof with moving parts membrane valves, flap valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE602006018206T 2006-06-23 2006-06-23 Anordnung einer mikrofluidvorrichtung zur analyse von biologischem material Active DE602006018206D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2006/000485 WO2007148358A1 (en) 2006-06-23 2006-06-23 Assembly of a microfluidic device for analysis of biological material

Publications (1)

Publication Number Publication Date
DE602006018206D1 true DE602006018206D1 (de) 2010-12-23

Family

ID=37708305

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018206T Active DE602006018206D1 (de) 2006-06-23 2006-06-23 Anordnung einer mikrofluidvorrichtung zur analyse von biologischem material

Country Status (5)

Country Link
US (1) US8808641B2 (de)
EP (1) EP2032255B1 (de)
CN (1) CN101505872B (de)
DE (1) DE602006018206D1 (de)
WO (1) WO2007148358A1 (de)

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US8021873B2 (en) 2008-07-16 2011-09-20 Boston Microfluidics Portable, point-of-care, user-initiated fluidic assay methods and systems
EP2382045A1 (de) * 2008-12-23 2011-11-02 STMicroelectronics S.r.l. Verfahren zur detektion des vorliegens von flüssigkeiten in einer mikrofluidikvorrichtung, detektionsvorrichtung und entsprechende mikrofluidikvorrichtung
IT1392842B1 (it) * 2008-12-29 2012-03-23 St Microelectronics Rousset Microreattore con canali di sfiato per rimuovere aria da una camera di reazione
US8931356B2 (en) * 2009-05-29 2015-01-13 Waters Technologies Corporation Chromatography apparatus and methods using multiple microfluidic substrates
WO2011050110A1 (en) * 2009-10-20 2011-04-28 Boston Microfluidics Methods and systems to collect and prepare samples, to implement, initiate and perform assays, and to control and manage fluid flow
JP5680950B2 (ja) * 2009-12-10 2015-03-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ マルチウェル・プレート及び蓋体
KR101266257B1 (ko) * 2010-05-18 2013-05-22 주식회사 나노엔텍 유체분석용 칩
US20110312709A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc device for detecting target nucleic acid sequences using electrochemiluminescent probes and calibration probes with detection photosensors and calibration photosensors
CA2808412C (en) * 2010-08-18 2021-10-12 Pressure Biosciences Inc. Flow-through high hydrostatic pressure microfluidic sample preparation device and related methods therefor
CN102728420B (zh) * 2011-04-13 2014-07-02 白向阳 异质倒置流式芯片及其制备方法
DE102011077101A1 (de) * 2011-06-07 2012-12-13 Robert Bosch Gmbh Mikrofluidisches System und Verfahren zum Betreiben eines solchen Systems
US9192934B2 (en) * 2012-10-25 2015-11-24 General Electric Company Insert assembly for a microfluidic device
DE102013207683A1 (de) 2013-04-26 2014-11-13 Robert Bosch Gmbh Verfahren und Vorrichtung zum Herstellen einer mikrofluidischen Analysekartusche
CN104764875B (zh) * 2015-01-27 2016-08-17 北京化工大学 唾液样品进样微流控装置
TWI581862B (zh) * 2015-06-16 2017-05-11 亞諾法生技股份有限公司 微流道裝置的夾持載具
US11371091B2 (en) 2015-06-22 2022-06-28 Fluxergy, Inc. Device for analyzing a fluid sample and use of test card with same
WO2016209735A1 (en) 2015-06-22 2016-12-29 Fluxergy, Llc Camera imaging system for a fluid sample assay and method of using same
US10214772B2 (en) * 2015-06-22 2019-02-26 Fluxergy, Llc Test card for assay and method of manufacturing same
JP6882782B2 (ja) 2015-08-04 2021-06-02 デューク ユニバーシティ 遺伝子コードされた本質的に無秩序な送達用ステルスポリマーおよびその使用方法
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
EP3199240A1 (de) * 2016-01-26 2017-08-02 ThinXXS Microtechnology AG Mikrofluidische flusszelle mit integrierter elektrode und verfahren zu ihrer herstellung
WO2017184998A1 (en) * 2016-04-22 2017-10-26 Arizona Board Of Regents On Behalf Of Arizona State University A device for high-throughput multi-parameter functional profiling of the same cells in multicellular settings and in isolation
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
WO2018067177A1 (en) * 2016-10-07 2018-04-12 Hewlett-Packard Development Company, L.P. Microfluidic chips
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US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
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Also Published As

Publication number Publication date
EP2032255A1 (de) 2009-03-11
WO2007148358A8 (en) 2008-06-19
CN101505872B (zh) 2011-12-28
US20090215194A1 (en) 2009-08-27
WO2007148358A1 (en) 2007-12-27
EP2032255B1 (de) 2010-11-10
US8808641B2 (en) 2014-08-19
CN101505872A (zh) 2009-08-12

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