ATE371867T1 - Überwachung von zellen - Google Patents

Überwachung von zellen

Info

Publication number
ATE371867T1
ATE371867T1 AT03762822T AT03762822T ATE371867T1 AT E371867 T1 ATE371867 T1 AT E371867T1 AT 03762822 T AT03762822 T AT 03762822T AT 03762822 T AT03762822 T AT 03762822T AT E371867 T1 ATE371867 T1 AT E371867T1
Authority
AT
Austria
Prior art keywords
monitoring cells
cells
monitoring
chamber
microfluidic
Prior art date
Application number
AT03762822T
Other languages
English (en)
Inventor
Christopher Robin Lowe
Craig J Gershater
Colin Davidson
Original Assignee
Smart Holograms Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smart Holograms Ltd filed Critical Smart Holograms Ltd
Application granted granted Critical
Publication of ATE371867T1 publication Critical patent/ATE371867T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163—Biocompatibility
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/019—Biological contaminants; Fouling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Clinical Laboratory Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT03762822T 2002-07-09 2003-07-09 Überwachung von zellen ATE371867T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0215879.8A GB0215879D0 (en) 2002-07-09 2002-07-09 Monitoring of cells

Publications (1)

Publication Number Publication Date
ATE371867T1 true ATE371867T1 (de) 2007-09-15

Family

ID=9940123

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03762822T ATE371867T1 (de) 2002-07-09 2003-07-09 Überwachung von zellen

Country Status (9)

Country Link
US (1) US20060051733A1 (de)
EP (1) EP1535064B1 (de)
JP (1) JP2005532060A (de)
AT (1) ATE371867T1 (de)
AU (1) AU2003246931B2 (de)
CA (1) CA2491896A1 (de)
DE (1) DE60315992T2 (de)
GB (1) GB0215879D0 (de)
WO (1) WO2004005922A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004098741A2 (en) 2003-04-30 2004-11-18 Biovitesse Apparatus and method for detecting live cells with an integrated filter and growth detection device
DE102004005337A1 (de) * 2004-02-04 2005-08-25 Studiengesellschaft Kohle Mbh Mikrofluidische Chips mit immanenten hydrophilen Oberflächen
JP2005253412A (ja) * 2004-03-15 2005-09-22 Masayasu Suzuki マイクロウェルアレイチップ、その製造方法及び被検体の活性検定方法
US7160425B2 (en) * 2004-03-25 2007-01-09 Hewlett-Packard Development Company, L.P. Cell transporter for a biodevice
ITPI20040046A1 (it) * 2004-06-18 2004-09-18 Univ Pisa Bioreattore per lo studio degli effetti sulle attivita' cellulari di stimoli imposti
KR100790880B1 (ko) * 2006-07-05 2008-01-02 삼성전자주식회사 자성 비드가 결합되어 있는 소수성 다공성 중합체가 벽면에결합되어 있는 마이크로채널 또는 마이크로챔버를포함하는 미세유동장치 및 그를 이용하는 방법
WO2009157211A1 (ja) 2008-06-26 2009-12-30 国立大学法人東京大学 培養細胞の活性計測方法、マイクロチャンバ、マイクロチャンバアレイ、培養容器および培養細胞の活性計測装置
CN102439165A (zh) * 2008-06-27 2012-05-02 麻省理工学院 用于代谢工程和其它应用的微流体微滴
US20140048424A1 (en) * 2011-04-27 2014-02-20 Ohio University Methods and devices for the detection of biofilms
DE102011075762A1 (de) 2011-05-12 2012-11-15 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Analysegerät zur automatisierten Bestimmung einer Messgröße einer Messflüssigkeit
US9204821B2 (en) * 2012-05-09 2015-12-08 Isense Medical Corp. Method of and apparatus for detecting upper respiratory bacterial infection from exhaled mammalian breath and colorimetric sensor array cartridge
GB201512600D0 (en) * 2015-07-17 2015-08-26 Koniku Ltd Cell culture, transport and investigation
CN107849510A (zh) * 2015-10-22 2018-03-27 松下知识产权经营株式会社 电化学测定器件以及电化学测定系统
US11474103B2 (en) 2017-02-17 2022-10-18 Koniku Inc. Systems for detection
CN108362629B (zh) * 2018-02-09 2021-02-05 中国计量科学研究院 大肠杆菌o157:h7单个活菌的快速检测方法及试剂盒
WO2024100056A1 (en) * 2022-11-08 2024-05-16 Lumicks Ca Holding B.V. Microfluidic device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2966904B2 (ja) * 1990-08-08 1999-10-25 株式会社日立製作所 細胞の処理方法、および処理装置
US5474774A (en) * 1994-03-25 1995-12-12 Jlb, Inc. Adhesion inhibiting composition
GB9406142D0 (en) * 1994-03-28 1994-05-18 British Tech Group A sensor
US6197575B1 (en) * 1998-03-18 2001-03-06 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
WO1999067639A1 (en) * 1998-06-25 1999-12-29 Caliper Technologies Corporation High throughput methods, systems and apparatus for performing cell based screening assays
US6561208B1 (en) * 2000-04-14 2003-05-13 Nanostream, Inc. Fluidic impedances in microfluidic system
US6653124B1 (en) * 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
EP1499705A2 (de) * 2002-05-01 2005-01-26 Massachusetts Institute of Technology Mikrofermentoren für schnelles screening und analyse von biochemischen prozessen

Also Published As

Publication number Publication date
GB0215879D0 (en) 2002-08-14
DE60315992D1 (de) 2007-10-11
WO2004005922A2 (en) 2004-01-15
EP1535064A2 (de) 2005-06-01
AU2003246931A1 (en) 2004-01-23
WO2004005922A3 (en) 2004-03-11
JP2005532060A (ja) 2005-10-27
US20060051733A1 (en) 2006-03-09
AU2003246931B2 (en) 2007-01-25
EP1535064B1 (de) 2007-08-29
CA2491896A1 (en) 2004-01-15
DE60315992T2 (de) 2008-01-24

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties