ATE375156T1 - Benzimidazol-derivate als menschliche chymase - inhibitoren - Google Patents
Benzimidazol-derivate als menschliche chymase - inhibitorenInfo
- Publication number
- ATE375156T1 ATE375156T1 AT01901397T AT01901397T ATE375156T1 AT E375156 T1 ATE375156 T1 AT E375156T1 AT 01901397 T AT01901397 T AT 01901397T AT 01901397 T AT01901397 T AT 01901397T AT E375156 T1 ATE375156 T1 AT E375156T1
- Authority
- AT
- Austria
- Prior art keywords
- halo
- optionally substituted
- oxo
- trihalomethyl
- alk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000007533 | 2000-01-17 | ||
JP2000392303 | 2000-12-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE375156T1 true ATE375156T1 (de) | 2007-10-15 |
Family
ID=26583615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01901397T ATE375156T1 (de) | 2000-01-17 | 2001-01-17 | Benzimidazol-derivate als menschliche chymase - inhibitoren |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1249450B1 (de) |
JP (1) | JP4059671B2 (de) |
KR (2) | KR20070057276A (de) |
CN (2) | CN1198819C (de) |
AT (1) | ATE375156T1 (de) |
AU (2) | AU777813B2 (de) |
CA (1) | CA2396908A1 (de) |
CZ (1) | CZ301504B6 (de) |
DE (1) | DE60130865T2 (de) |
DK (1) | DK1249450T3 (de) |
ES (1) | ES2295128T3 (de) |
HK (1) | HK1050009A1 (de) |
IL (1) | IL150565A0 (de) |
NO (1) | NO324049B1 (de) |
NZ (1) | NZ520028A (de) |
PT (1) | PT1249450E (de) |
RU (1) | RU2263674C2 (de) |
SI (1) | SI1249450T1 (de) |
WO (1) | WO2001053291A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL358494A1 (en) * | 2001-02-22 | 2004-08-09 | Teijin Limited | Benzo[b]thiophene derivative and process for producing the same |
ATE404551T1 (de) * | 2001-05-07 | 2008-08-15 | Teijin Pharma Ltd | 3-hydroxymethylbenzo b thiophen-derivate und verfahren zu deren herstellung |
CN1520314A (zh) * | 2001-08-24 | 2004-08-11 | 帝人株式会社 | 含有食糜酶抑制剂和ace抑制剂作为有效成分的药物 |
CL2004001034A1 (es) * | 2003-05-14 | 2005-03-28 | Teijin Pharma Ltd | Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r |
EP1666067A4 (de) * | 2003-08-22 | 2009-07-22 | Teijin Pharma Ltd | Arzneimittel mit chymase-hemmer als wirkstoff |
US20080015240A1 (en) * | 2004-11-12 | 2008-01-17 | Mitsuru Teramoto | Acid Salt of Benzimidazole Derivative and Crystal Thereof |
US20090155361A1 (en) | 2005-08-18 | 2009-06-18 | Masahiko Narasaki | Tablet with multiple drug-containing sections |
CN102008392B (zh) | 2005-08-18 | 2013-07-31 | 帝人制药株式会社 | 具有准确的用量分割功能的制剂 |
TW200734321A (en) | 2005-10-27 | 2007-09-16 | Teijin Pharma Ltd | Benzo [b] thiophen derivatives and a process for producing benzo [b] thiophen derivatives |
EP1947096A1 (de) | 2005-10-27 | 2008-07-23 | Teijin Pharma Limited | 3-HYDROXYMETHYLBENZO[b]THIOPHENDERIVAT UND VERFAHREN ZU DESSEN HERSTELLUNG |
PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
UA95788C2 (en) * | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
EP2152674B1 (de) | 2007-05-22 | 2011-08-03 | Boehringer Ingelheim International GmbH | Benzimidazolonchymasehemmer |
JP5615700B2 (ja) * | 2007-05-25 | 2014-10-29 | アボット ゲーエムベーハー ウント カンパニー カーゲー | 代謝型グルタミン酸受容体2(mglu2受容体)の陽性調節剤としての複素環化合物 |
WO2008153129A1 (ja) * | 2007-06-14 | 2008-12-18 | Teijin Pharma Limited | 尿酸値低下剤 |
WO2009133964A1 (ja) * | 2008-04-28 | 2009-11-05 | 国立大学法人九州大学 | 酸化ストレス抑制剤 |
WO2010030500A1 (en) * | 2008-09-09 | 2010-03-18 | Boehringer Ingelheim International Gmbh | Aza-benzimidazolone chymase inhibitors |
AU2009296820B2 (en) | 2008-09-26 | 2014-03-20 | Merck Sharp & Dohme Llc | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
CN102264228A (zh) | 2008-10-22 | 2011-11-30 | 默沙东公司 | 用于抗糖尿病药的新的环状苯并咪唑衍生物 |
US8563746B2 (en) | 2008-10-29 | 2013-10-22 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
AU2009309037A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
CN102741245B (zh) * | 2009-11-18 | 2014-11-05 | 尼奥梅德研究院 | 苯并咪唑化合物及其用途 |
AU2011218830B2 (en) | 2010-02-25 | 2014-07-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
PE20140859A1 (es) | 2011-02-25 | 2014-07-25 | Merck Sharp & Dohme | Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos |
CA2872000A1 (en) * | 2012-05-04 | 2013-11-07 | Novartis Ag | Complement pathway modulators and uses thereof |
JP2015525782A (ja) | 2012-08-02 | 2015-09-07 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病性三環式化合物 |
EP2888008B1 (de) | 2012-08-22 | 2018-12-26 | Merck Sharp & Dohme Corp. | Neuartige azabenzimidazol-tetrahydrofuranderivate |
BR112015003109A2 (pt) | 2012-08-22 | 2017-08-15 | Merck Sharp & Dohme | Composto, composição, uso de um composto, e, métodos para tratar ou prevenir um distúrbio, condição ou doença e para tratar diabetes mellitus tipo 2. |
WO2014031441A1 (en) | 2012-08-22 | 2014-02-27 | Merck Sharp & Dohme Corp. | Novel benzimidazole tetrahydrofuran derivatives |
EP2887807B1 (de) | 2012-08-22 | 2019-09-18 | Merck Sharp & Dohme Corp. | Benzimidazol-hexahydrofuro[3,2-b]furanderivate als amp-aktivierte proteinkinase-aktivatoren |
WO2014031465A1 (en) | 2012-08-22 | 2014-02-27 | Merck Sharp & Dohme Corp. | Novel azabenzimidazole tetrahydropyran derivatives |
WO2014031445A1 (en) | 2012-08-22 | 2014-02-27 | Merck Sharp & Dohme Corp. | Novel benzimidazole tetrahydropyran derivatives |
US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
EP3068768B1 (de) | 2013-11-15 | 2019-07-31 | Merck Sharp & Dohme Corp. | Antidiabetische tricyclische verbindungen |
WO2015089809A1 (en) | 2013-12-19 | 2015-06-25 | Merck Sharp & Dohme Corp. | Antidiabetic substituted heteroaryl compounds |
CN111004125B (zh) * | 2019-12-24 | 2022-11-22 | 东华理工大学 | 一种缩醛或缩酮化合物的制备方法 |
CN116903541B (zh) * | 2023-08-14 | 2023-12-08 | 中国环境科学研究院 | 用于酚类污染物检测的酰基咪唑类化合物、制备方法及应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2430950A1 (fr) * | 1978-07-10 | 1980-02-08 | Delalande Sa | Nouveaux derives heterocycliques de la benzimidazole, leur procede de preparation et leur application en therapeutique |
DE2928055A1 (de) * | 1978-07-12 | 1980-01-31 | Eastman Kodak Co | Verfahren zur verbesserung der widerstandsfaehigkeit von polyesterformkoerpern gegenueber einem abbau durch u.v.- licht |
JPS62212386A (ja) * | 1986-03-14 | 1987-09-18 | Suntory Ltd | 2−ピリジルメチルベンズイミダゾ−ル誘導体 |
JPH01265089A (ja) * | 1988-04-15 | 1989-10-23 | Zeria Pharmaceut Co Ltd | 新規1−(イミダゾール−4−イル)メチルベンズイミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤 |
GB9225141D0 (en) * | 1992-12-01 | 1993-01-20 | Smithkline Beecham Corp | Chemical compounds |
US5527597A (en) * | 1995-03-01 | 1996-06-18 | Southern Mills, Inc. | Stretchable flame resistant fabric |
WO1999026932A1 (en) * | 1997-11-26 | 1999-06-03 | Axys Pharmaceuticals, Inc. | By amidino group substituted heterocyclic derivatives and their use as anticoagulants |
BR9912098A (pt) * | 1998-07-15 | 2001-09-25 | Teijin Ltd | Derivado de tiobenzimidazol, composição farmacêutica, e, agente preventivo e/ou terapêutico |
DE60033859T2 (de) * | 1999-06-28 | 2007-11-08 | Janssen Pharmaceutica N.V. | Hemmer des Respiratorischen Syncytial Virus |
CZ2001153A3 (cs) * | 1999-07-14 | 2001-06-13 | Teijin Ltd | Thiobenzimidazolové deriváty |
-
2001
- 2001-01-17 RU RU2002122105/04A patent/RU2263674C2/ru not_active IP Right Cessation
- 2001-01-17 CA CA002396908A patent/CA2396908A1/en not_active Abandoned
- 2001-01-17 EP EP01901397A patent/EP1249450B1/de not_active Expired - Lifetime
- 2001-01-17 KR KR1020077010650A patent/KR20070057276A/ko active IP Right Grant
- 2001-01-17 CN CNB018066623A patent/CN1198819C/zh not_active Expired - Fee Related
- 2001-01-17 NZ NZ520028A patent/NZ520028A/en unknown
- 2001-01-17 KR KR1020027009200A patent/KR100763779B1/ko not_active IP Right Cessation
- 2001-01-17 JP JP2001553765A patent/JP4059671B2/ja not_active Expired - Fee Related
- 2001-01-17 DK DK01901397T patent/DK1249450T3/da active
- 2001-01-17 IL IL15056501A patent/IL150565A0/xx not_active IP Right Cessation
- 2001-01-17 PT PT01901397T patent/PT1249450E/pt unknown
- 2001-01-17 AU AU27049/01A patent/AU777813B2/en not_active Ceased
- 2001-01-17 CN CNB2005100526041A patent/CN100415723C/zh not_active Expired - Fee Related
- 2001-01-17 WO PCT/JP2001/000271 patent/WO2001053291A1/ja active IP Right Grant
- 2001-01-17 ES ES01901397T patent/ES2295128T3/es not_active Expired - Lifetime
- 2001-01-17 CZ CZ20022442A patent/CZ301504B6/cs not_active IP Right Cessation
- 2001-01-17 DE DE60130865T patent/DE60130865T2/de not_active Expired - Lifetime
- 2001-01-17 SI SI200130792T patent/SI1249450T1/sl unknown
- 2001-01-17 AT AT01901397T patent/ATE375156T1/de not_active IP Right Cessation
-
2002
- 2002-07-16 NO NO20023415A patent/NO324049B1/no not_active IP Right Cessation
-
2003
- 2003-03-31 HK HK03102300A patent/HK1050009A1/xx not_active IP Right Cessation
-
2005
- 2005-01-14 AU AU2005200172A patent/AU2005200172B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DE60130865D1 (de) | 2007-11-22 |
CA2396908A1 (en) | 2001-07-26 |
KR20020065929A (ko) | 2002-08-14 |
WO2001053291A1 (fr) | 2001-07-26 |
DK1249450T3 (da) | 2008-02-11 |
AU2704901A (en) | 2001-07-31 |
IL150565A0 (en) | 2003-02-12 |
HK1050009A1 (en) | 2003-06-06 |
ES2295128T3 (es) | 2008-04-16 |
CZ301504B6 (cs) | 2010-03-24 |
CN1680339A (zh) | 2005-10-12 |
DE60130865T2 (de) | 2008-07-17 |
CN1418211A (zh) | 2003-05-14 |
CN100415723C (zh) | 2008-09-03 |
AU2005200172B2 (en) | 2007-08-23 |
AU777813B2 (en) | 2004-11-04 |
SI1249450T1 (sl) | 2008-04-30 |
NO20023415D0 (no) | 2002-07-16 |
RU2263674C2 (ru) | 2005-11-10 |
CN1198819C (zh) | 2005-04-27 |
EP1249450A4 (de) | 2003-04-09 |
NO20023415L (no) | 2002-07-16 |
EP1249450A1 (de) | 2002-10-16 |
KR20070057276A (ko) | 2007-06-04 |
NO324049B1 (no) | 2007-08-06 |
EP1249450B1 (de) | 2007-10-10 |
NZ520028A (en) | 2004-07-30 |
KR100763779B1 (ko) | 2007-10-05 |
PT1249450E (pt) | 2008-01-02 |
AU2005200172A1 (en) | 2005-02-10 |
JP4059671B2 (ja) | 2008-03-12 |
RU2002122105A (ru) | 2004-01-10 |
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