ATE321758T1 - Verbessertes verfahren zur herstellung von verbindungen des benzimidazoltyps - Google Patents
Verbessertes verfahren zur herstellung von verbindungen des benzimidazoltypsInfo
- Publication number
- ATE321758T1 ATE321758T1 AT02754865T AT02754865T ATE321758T1 AT E321758 T1 ATE321758 T1 AT E321758T1 AT 02754865 T AT02754865 T AT 02754865T AT 02754865 T AT02754865 T AT 02754865T AT E321758 T1 ATE321758 T1 AT E321758T1
- Authority
- AT
- Austria
- Prior art keywords
- improved method
- type compounds
- benzimidazole type
- producing benzimidazole
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Extraction Or Liquid Replacement (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202696 | 2001-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321758T1 true ATE321758T1 (de) | 2006-04-15 |
Family
ID=8180641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02754865T ATE321758T1 (de) | 2001-07-16 | 2002-07-09 | Verbessertes verfahren zur herstellung von verbindungen des benzimidazoltyps |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6919459B2 (de) |
| EP (1) | EP1409478B1 (de) |
| JP (1) | JP4320250B2 (de) |
| KR (1) | KR100914175B1 (de) |
| CN (1) | CN1235899C (de) |
| AT (1) | ATE321758T1 (de) |
| AU (1) | AU2002321204B2 (de) |
| BR (1) | BRPI0211101B8 (de) |
| CA (1) | CA2450433C (de) |
| CZ (1) | CZ304526B6 (de) |
| DE (1) | DE60210292T2 (de) |
| EA (1) | EA005773B1 (de) |
| EE (1) | EE05402B1 (de) |
| ES (1) | ES2261703T3 (de) |
| HK (1) | HK1069168A1 (de) |
| HU (1) | HU230155B1 (de) |
| IL (2) | IL159854A0 (de) |
| MX (1) | MXPA04000433A (de) |
| NO (1) | NO324257B1 (de) |
| NZ (1) | NZ530168A (de) |
| PL (1) | PL208291B1 (de) |
| SK (1) | SK287245B6 (de) |
| WO (1) | WO2003008406A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003278406A1 (en) * | 2002-10-22 | 2004-05-13 | Ranbaxy Laboratories Limited | Amorphous form of esomeprazole salts |
| CA2528993A1 (en) * | 2003-06-10 | 2004-12-23 | Teva Pharmaceutical Industries Ltd. | Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
| JP4987477B2 (ja) * | 2004-08-20 | 2012-07-25 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ベンズイミダゾール誘導体の製造方法 |
| WO2006049486A1 (en) * | 2004-11-08 | 2006-05-11 | Dishman Pharmaceuticals And Chemicals Ltd. | A PREPARATION METHOD FOR SUBSTITUTED 2-(2-PYRIDYLMETHOYLSULPHINYL)-l-H-BENZIMID AZOLES |
| EP1681056A1 (de) | 2005-01-14 | 2006-07-19 | Krka Tovarna Zdravil, D.D., Novo Mesto | Verfahren zur Herstellung von Lansoprazol |
| GB0525710D0 (en) * | 2005-12-17 | 2006-01-25 | Pliva Hrvatska D O O | An improved process for preparing of substituted 2-benzimidazolesulfoxide compounds |
| EP1801110A1 (de) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Argininsalz des Esomeprazols |
| EP1818331A1 (de) | 2006-02-14 | 2007-08-15 | EOS Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ti Caret A.S. | Verfahren zur Herstellung von 2-[{4-(3-Methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazol wesentlich frei von Sulfonverunreinigung |
| WO2007129328A2 (en) * | 2006-05-09 | 2007-11-15 | Cadila Healthcare Limited | Process for preparing 2-[pyridinyl]sulfinyl-substituted benzimidazoles |
| WO2007138468A2 (en) * | 2006-06-01 | 2007-12-06 | Wockhardt Ltd | Processes for the preparation of lansoprazole |
| WO2008017020A2 (en) * | 2006-08-03 | 2008-02-07 | Dr. Reddy's Laboratories Limited | Process for preparing proton pump inhibitors |
| EP2069329A4 (de) * | 2006-10-06 | 2010-04-07 | Reddys Lab Ltd Dr | Verfahren zur herstellung von benzimidazol-derivaten und ihren salzen |
| EP1947099A1 (de) | 2007-01-18 | 2008-07-23 | LEK Pharmaceuticals D.D. | Verfahren zur Entfernung von Lösungsmitteln in Omeprazol-Salzen |
| WO2008152462A1 (en) * | 2007-06-15 | 2008-12-18 | Emcure Pharmaceuticals Limited | A process of sulfoxidation of biologically active compounds |
| US8247568B2 (en) * | 2007-06-21 | 2012-08-21 | Matrix Laboratories Ltd | Process for the preparation of pure rabeprazole |
| EP2022789A1 (de) * | 2007-08-06 | 2009-02-11 | Farmaprojects, S.A. | Verfahren zur Herstellung eines Magensäuresekretionshemmers |
| WO2009066317A2 (en) * | 2007-08-20 | 2009-05-28 | Macleods Pharmaceuticals Limited | Process for the preparation of pantoprazole sodium |
| EP2030973A1 (de) * | 2007-08-31 | 2009-03-04 | KRKA, tovarna zdravil, d.d., Novo mesto | Verfahren zur Herstellung von 2-Sulfinyl-1H-Benzimidazolen |
| US8071781B2 (en) * | 2008-11-11 | 2011-12-06 | Syn-Tech Chem. & Pharm. Co., Ltd. | Process for preparing rabeprazole sodium |
| WO2011109308A1 (en) * | 2010-03-02 | 2011-09-09 | Seattle Genetics, Inc. | Methods for screening antibodies |
| CN104418837A (zh) * | 2013-08-19 | 2015-03-18 | 长沙市如虹医药科技有限公司 | 一种氧化硫醚成亚砜的方法 |
| CN104402867A (zh) * | 2014-11-07 | 2015-03-11 | 烟台万润精细化工股份有限公司 | 一种制备埃索美拉唑杂质h和b的方法 |
| CN104402866A (zh) * | 2014-11-07 | 2015-03-11 | 烟台万润精细化工股份有限公司 | 一种制备埃索美拉唑杂质j和k的方法 |
| CN104530006B (zh) * | 2015-01-06 | 2018-05-11 | 江苏奥赛康药业股份有限公司 | 兰索拉唑的制备方法 |
| CN104744440B (zh) * | 2015-03-12 | 2016-09-07 | 常州康丽制药有限公司 | 雷贝拉唑硫醚的回收方法 |
| CN110487918B (zh) * | 2018-05-14 | 2022-02-08 | 中国医学科学院药物研究所 | 泮托拉唑钠及其起始原料中基因毒性杂质的分析方法 |
| CN109354587B (zh) * | 2018-10-18 | 2020-09-18 | 成都天台山制药有限公司 | 泮托拉唑钠的制备方法和泮托拉唑钠 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| NZ244301A (en) * | 1991-09-20 | 1994-08-26 | Merck & Co Inc | Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds |
| KR960002912B1 (ko) * | 1993-02-19 | 1996-02-28 | 영진약품공업주식회사 | 신규한 벤즈이미다졸 유도체 |
| ES2094694B1 (es) | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion. |
| CN1053444C (zh) * | 1996-03-20 | 2000-06-14 | 常州市第四制药厂 | 奥美拉唑的一种精制方法 |
| SK283805B6 (sk) * | 1996-09-09 | 2004-02-03 | Slovakofarma, A. S. | Spôsob prípravy omeprazolu |
| SI20019A (sl) * | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
-
2002
- 2002-07-09 NZ NZ530168A patent/NZ530168A/en not_active IP Right Cessation
- 2002-07-09 HU HU0400610A patent/HU230155B1/hu unknown
- 2002-07-09 EA EA200400185A patent/EA005773B1/ru not_active IP Right Cessation
- 2002-07-09 ES ES02754865T patent/ES2261703T3/es not_active Expired - Lifetime
- 2002-07-09 DE DE60210292T patent/DE60210292T2/de not_active Expired - Lifetime
- 2002-07-09 SK SK92-2004A patent/SK287245B6/sk not_active IP Right Cessation
- 2002-07-09 AU AU2002321204A patent/AU2002321204B2/en not_active Expired
- 2002-07-09 CA CA2450433A patent/CA2450433C/en not_active Expired - Lifetime
- 2002-07-09 WO PCT/EP2002/007693 patent/WO2003008406A1/en active IP Right Grant
- 2002-07-09 BR BRPI0211101A patent/BRPI0211101B8/pt not_active IP Right Cessation
- 2002-07-09 EE EEP200400052A patent/EE05402B1/xx unknown
- 2002-07-09 CN CNB028139615A patent/CN1235899C/zh not_active Expired - Lifetime
- 2002-07-09 AT AT02754865T patent/ATE321758T1/de not_active IP Right Cessation
- 2002-07-09 CZ CZ2004-208A patent/CZ304526B6/cs not_active IP Right Cessation
- 2002-07-09 KR KR1020037015941A patent/KR100914175B1/ko active IP Right Grant
- 2002-07-09 MX MXPA04000433A patent/MXPA04000433A/es active IP Right Grant
- 2002-07-09 PL PL367006A patent/PL208291B1/pl unknown
- 2002-07-09 JP JP2003513965A patent/JP4320250B2/ja not_active Expired - Lifetime
- 2002-07-09 US US10/483,587 patent/US6919459B2/en not_active Expired - Lifetime
- 2002-07-09 EP EP02754865A patent/EP1409478B1/de not_active Expired - Lifetime
- 2002-07-09 IL IL15985402A patent/IL159854A0/xx unknown
-
2004
- 2004-01-08 NO NO20040074A patent/NO324257B1/no not_active IP Right Cessation
- 2004-01-14 IL IL159854A patent/IL159854A/en active IP Right Grant
-
2005
- 2005-02-25 HK HK05101607A patent/HK1069168A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |