ATE534643T1 - Verbessertes verfahren zur herstellung eines optisch aktiven protonenpumpenhemmers - Google Patents
Verbessertes verfahren zur herstellung eines optisch aktiven protonenpumpenhemmersInfo
- Publication number
- ATE534643T1 ATE534643T1 AT08762768T AT08762768T ATE534643T1 AT E534643 T1 ATE534643 T1 AT E534643T1 AT 08762768 T AT08762768 T AT 08762768T AT 08762768 T AT08762768 T AT 08762768T AT E534643 T1 ATE534643 T1 AT E534643T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- optically active
- improved method
- proton pump
- pump inhibitor
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126409 proton pump inhibitor Drugs 0.000 title 1
- 239000000612 proton pump inhibitor Substances 0.000 title 1
- SUBDBMMJDZJVOS-DEOSSOPVSA-N esomeprazole Chemical compound C([S@](=O)C1=NC2=CC=C(C=C2N1)OC)C1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-DEOSSOPVSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1174CH2007 | 2007-06-07 | ||
| PCT/IB2008/001427 WO2008149204A1 (en) | 2007-06-07 | 2008-05-30 | An improved process for preparing an optically active proton pump inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE534643T1 true ATE534643T1 (de) | 2011-12-15 |
Family
ID=39877811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08762768T ATE534643T1 (de) | 2007-06-07 | 2008-05-30 | Verbessertes verfahren zur herstellung eines optisch aktiven protonenpumpenhemmers |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8492551B2 (de) |
| EP (1) | EP2152691B1 (de) |
| AT (1) | ATE534643T1 (de) |
| WO (1) | WO2008149204A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010118575A1 (en) * | 2009-04-16 | 2010-10-21 | Chengdu Organic Chemicals Co., Ltd, Chinese Academy Of Science | Racemic enantiomers resoluting |
| EP2486032A4 (de) * | 2009-10-09 | 2013-03-27 | Hetero Research Foundation | Racematspaltung substituierter 2-(2-pyridinylmethylsulfinyl)-1h-benzimidazole |
| WO2011058569A1 (en) * | 2009-11-12 | 2011-05-19 | Hetero Research Foundation | Process for the resolution of omeprazole |
| KR20120114356A (ko) | 2010-02-12 | 2012-10-16 | 에스티브 퀴미카 에스.에이. | 에스오메프라졸 나트륨염의 제조공정 |
| CN104530003A (zh) * | 2014-06-10 | 2015-04-22 | 广东东阳光药业有限公司 | 吡啶甲基亚磺酰基-1h-苯并咪唑类化合物的盐的制备方法 |
| CN106397402B (zh) * | 2016-08-30 | 2019-05-03 | 山东罗欣药业集团股份有限公司 | 一种埃索美拉唑镁晶型化合物及其制备方法 |
| CN113278008B (zh) * | 2021-07-26 | 2021-11-26 | 寿光富康制药有限公司 | 一种大颗粒三水合埃索美拉唑镁的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| SE510650C2 (sv) * | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
| CN1087739C (zh) | 1998-12-28 | 2002-07-17 | 中国科学院成都有机化学研究所 | 光学纯的苯并咪唑类抗消化性溃疡药物的包结拆分制备法 |
| WO2004002982A2 (en) * | 2002-06-27 | 2004-01-08 | Dr. Reddy's Laboratories Limited | A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof |
| ES2259269B1 (es) * | 2005-03-03 | 2007-11-01 | Esteve Quimica, S.A. | Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos. |
| KR100641534B1 (ko) * | 2005-07-28 | 2006-11-01 | 한미약품 주식회사 | 에스오메프라졸 및 그의 염의 제조방법 |
| BRPI0621832A2 (pt) * | 2006-07-05 | 2013-03-19 | Lupin Ltd | processo para a preparaÇço de enantiâmeros oticamente puros ou oticamente enriquecidos de compostos de sulfàxido |
| KR101522219B1 (ko) * | 2007-02-21 | 2015-05-21 | 시플라 리미티드 | 에소메프라졸 마그네슘 2수화물의 제조방법 |
-
2008
- 2008-05-30 AT AT08762768T patent/ATE534643T1/de active
- 2008-05-30 US US12/451,871 patent/US8492551B2/en not_active Expired - Fee Related
- 2008-05-30 WO PCT/IB2008/001427 patent/WO2008149204A1/en not_active Ceased
- 2008-05-30 EP EP08762768A patent/EP2152691B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2152691A1 (de) | 2010-02-17 |
| WO2008149204A1 (en) | 2008-12-11 |
| EP2152691B1 (de) | 2011-11-23 |
| US20100125142A1 (en) | 2010-05-20 |
| US8492551B2 (en) | 2013-07-23 |
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