ATE196845T1 - Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind - Google Patents

Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind

Info

Publication number
ATE196845T1
ATE196845T1 AT96202848T AT96202848T ATE196845T1 AT E196845 T1 ATE196845 T1 AT E196845T1 AT 96202848 T AT96202848 T AT 96202848T AT 96202848 T AT96202848 T AT 96202848T AT E196845 T1 ATE196845 T1 AT E196845T1
Authority
AT
Austria
Prior art keywords
clavulanates
covered
water
polymer film
based polymer
Prior art date
Application number
AT96202848T
Other languages
English (en)
Inventor
Creighton Pierce Conley
Nigel Philip Davidson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE196845(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE196845T1 publication Critical patent/ATE196845T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT96202848T 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind ATE196845T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE196845T1 true ATE196845T1 (de) 2000-10-15

Family

ID=10754044

Family Applications (6)

Application Number Title Priority Date Filing Date
AT00204182T ATE226074T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT95917937T ATE203161T1 (de) 1994-04-23 1995-04-19 Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
AT99200891T ATE223706T1 (de) 1994-04-23 1995-04-19 Tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerüberzug versehen sind
AT96202848T ATE196845T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT0052400U AT5349U1 (de) 1994-04-23 2000-07-18 Polymerbeschichtete tablette umfassend amoxycillin und clavulanat
AT0028501U AT5350U1 (de) 1994-04-23 2001-04-11 Medikament zur oralen verabreichung

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AT00204182T ATE226074T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT95917937T ATE203161T1 (de) 1994-04-23 1995-04-19 Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
AT99200891T ATE223706T1 (de) 1994-04-23 1995-04-19 Tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerüberzug versehen sind

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT0052400U AT5349U1 (de) 1994-04-23 2000-07-18 Polymerbeschichtete tablette umfassend amoxycillin und clavulanat
AT0028501U AT5350U1 (de) 1994-04-23 2001-04-11 Medikament zur oralen verabreichung

Country Status (35)

Country Link
US (1) US6051255A (de)
EP (5) EP1093813B1 (de)
JP (1) JP3622975B2 (de)
CN (1) CN1134258C (de)
AP (2) AP564A (de)
AT (6) ATE226074T1 (de)
AU (1) AU684949B2 (de)
BG (1) BG62842B1 (de)
BR (1) BR9507502A (de)
CA (1) CA2188496A1 (de)
CZ (2) CZ294168B6 (de)
DE (5) DE69528608T2 (de)
DK (4) DK0978276T3 (de)
DZ (1) DZ1876A1 (de)
ES (4) ES2182754T3 (de)
FI (1) FI964249A7 (de)
GB (1) GB9408117D0 (de)
GR (2) GR3035031T3 (de)
HK (1) HK1050992A1 (de)
HU (1) HU228399B1 (de)
IL (1) IL113433A (de)
MA (1) MA23528A1 (de)
MY (1) MY115351A (de)
NO (1) NO310703B1 (de)
NZ (1) NZ285080A (de)
OA (1) OA10377A (de)
PL (1) PL316966A1 (de)
PT (4) PT978276E (de)
RO (1) RO116997B1 (de)
RU (1) RU2152213C1 (de)
SA (1) SA95160343B1 (de)
SI (1) SI0758235T1 (de)
SK (1) SK282594B6 (de)
WO (1) WO1995028927A1 (de)
ZA (1) ZA953236B (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
TR199800415T1 (en) * 1995-09-07 1998-05-21 Smithkline Beecham Corporation Farmas�tik form�lasyon.
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
CA2280857A1 (en) * 1997-02-14 1998-08-20 Smithkline Beecham Laboratoires Pharmaceutiques Pharmaceutical formulations comprising amoxocyllin and clavulanate
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
EP1023065A1 (de) * 1997-08-29 2000-08-02 Dsm N.V. Zusatzfreie granulate
US6326028B1 (en) 1997-10-31 2001-12-04 Monsanto Company Alginate and gellan gum as tablet coating
CA2364342C (en) 1999-04-01 2011-02-01 Dsm N.V. Agglomerates by crystallisation
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
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US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
US20120172427A1 (en) * 2009-09-18 2012-07-05 Sanofi (z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide tablet formulations with improved stability
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
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GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
NO329694B1 (no) * 1999-04-13 2010-12-06 Beecham Pharm Pte Ltd Farmasoytisk formulering og anvendelse derav, samt belagt tablett
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Also Published As

Publication number Publication date
HK1027024A1 (en) 2001-01-05
AU2406895A (en) 1995-11-16
DE69528204D1 (de) 2002-10-17
BG62842B1 (bg) 2000-09-29
HU228399B1 (en) 2013-03-28
PT978276E (pt) 2003-01-31
BG100933A (en) 1997-07-31
AP564A (en) 1996-11-21
PT758235E (pt) 2001-10-31
EP0978276A2 (de) 2000-02-09
JPH09512027A (ja) 1997-12-02
EP0978276B1 (de) 2002-09-11
EP1243267A2 (de) 2002-09-25
AU684949B2 (en) 1998-01-08
HK1050992A1 (en) 2003-07-18
DE69528204T2 (de) 2003-08-07
EP0761218B1 (de) 2000-10-11
AT5350U1 (de) 2002-06-25
EP0978276A3 (de) 2000-04-12
IL113433A0 (en) 1995-07-31
FI964249A0 (fi) 1996-10-22
CA2188496A1 (en) 1995-11-02
DK1093813T3 (da) 2003-02-17
DE29522153U1 (de) 2000-04-06
EP0758235A1 (de) 1997-02-19
IL113433A (en) 2003-06-24
ES2152485T3 (es) 2001-02-01
ZA953236B (en) 1995-12-27
RO116997B1 (ro) 2001-09-28
CN1149829A (zh) 1997-05-14
HUT76335A (en) 1997-08-28
MY115351A (en) 2003-05-31
ES2182754T3 (es) 2003-03-16
DZ1876A1 (fr) 2002-02-17
DE69521799D1 (de) 2001-08-23
EP1093813A2 (de) 2001-04-25
NO964488L (no) 1996-12-17
MA23528A1 (fr) 1995-12-31
RU2152213C1 (ru) 2000-07-10
GB9408117D0 (en) 1994-06-15
ES2180251T3 (es) 2003-02-01
US6051255A (en) 2000-04-18
SK135496A3 (en) 1997-05-07
PL316966A1 (en) 1997-03-03
CN1134258C (zh) 2004-01-14
EP0758235B1 (de) 2001-07-18
SA95160343B1 (ar) 2005-05-04
GR3036844T3 (en) 2002-01-31
AP9500733A0 (en) 1995-04-30
CZ294168B6 (cs) 2004-10-13
NO964488D0 (no) 1996-10-22
CZ309096A3 (en) 1997-04-16
EP1093813B1 (de) 2002-10-16
HK1009936A1 (en) 1999-06-11
CZ11376U1 (cs) 2001-07-12
SI0758235T1 (en) 2001-10-31
AT5349U1 (de) 2002-06-25
HK1021860A1 (en) 2000-07-07
NZ285080A (en) 1998-05-27
ES2161288T3 (es) 2001-12-01
EP1243267A3 (de) 2002-10-30
ATE223706T1 (de) 2002-09-15
DE69528608T2 (de) 2003-06-26
NO310703B1 (no) 2001-08-20
GR3035031T3 (en) 2001-03-30
FI964249L (fi) 1996-10-22
ATE226074T1 (de) 2002-11-15
HU9602922D0 (en) 1996-12-30
DE69519093D1 (de) 2000-11-16
WO1995028927A1 (en) 1995-11-02
DK0978276T3 (da) 2003-01-20
BR9507502A (pt) 1997-09-02
PT1093813E (pt) 2003-02-28
OA10377A (en) 2001-11-21
FI964249A7 (fi) 1996-10-22
JP3622975B2 (ja) 2005-02-23
ATE203161T1 (de) 2001-08-15
DK0758235T3 (da) 2001-10-29
HK1036404A1 (en) 2002-01-04
DE69528608D1 (de) 2002-11-21
DE69519093T2 (de) 2001-07-19
EP1093813A3 (de) 2001-05-30
DE69521799T2 (de) 2002-06-13
AP9600868A0 (en) 1996-10-31
SK282594B6 (sk) 2002-10-08
PT761218E (pt) 2001-03-30
DK0761218T3 (da) 2000-12-18
EP0761218A1 (de) 1997-03-12

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