ATE196845T1 - Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind - Google Patents

Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind

Info

Publication number
ATE196845T1
ATE196845T1 AT96202848T AT96202848T ATE196845T1 AT E196845 T1 ATE196845 T1 AT E196845T1 AT 96202848 T AT96202848 T AT 96202848T AT 96202848 T AT96202848 T AT 96202848T AT E196845 T1 ATE196845 T1 AT E196845T1
Authority
AT
Austria
Prior art keywords
clavulanates
covered
water
polymer film
based polymer
Prior art date
Application number
AT96202848T
Other languages
English (en)
Inventor
Creighton Pierce Conley
Nigel Philip Davidson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE196845(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE196845T1 publication Critical patent/ATE196845T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
AT96202848T 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind ATE196845T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE196845T1 true ATE196845T1 (de) 2000-10-15

Family

ID=10754044

Family Applications (6)

Application Number Title Priority Date Filing Date
AT96202848T ATE196845T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT99200891T ATE223706T1 (de) 1994-04-23 1995-04-19 Tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerüberzug versehen sind
AT95917937T ATE203161T1 (de) 1994-04-23 1995-04-19 Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
AT00204182T ATE226074T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT0052400U AT5349U1 (de) 1994-04-23 2000-07-18 Polymerbeschichtete tablette umfassend amoxycillin und clavulanat
AT0028501U AT5350U1 (de) 1994-04-23 2001-04-11 Medikament zur oralen verabreichung

Family Applications After (5)

Application Number Title Priority Date Filing Date
AT99200891T ATE223706T1 (de) 1994-04-23 1995-04-19 Tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerüberzug versehen sind
AT95917937T ATE203161T1 (de) 1994-04-23 1995-04-19 Polymer umhüllte tablette enthaltend amoxicillin und clavulanat
AT00204182T ATE226074T1 (de) 1994-04-23 1995-04-19 Verfahren zur herstellung von tabletten enthaltend amoxicillin und clavulanate, die mit einem polymerfilm auf wasserbasis versehen sind
AT0052400U AT5349U1 (de) 1994-04-23 2000-07-18 Polymerbeschichtete tablette umfassend amoxycillin und clavulanat
AT0028501U AT5350U1 (de) 1994-04-23 2001-04-11 Medikament zur oralen verabreichung

Country Status (35)

Country Link
US (1) US6051255A (de)
EP (5) EP0978276B1 (de)
JP (1) JP3622975B2 (de)
CN (1) CN1134258C (de)
AP (2) AP564A (de)
AT (6) ATE196845T1 (de)
AU (1) AU684949B2 (de)
BG (1) BG62842B1 (de)
BR (1) BR9507502A (de)
CA (1) CA2188496A1 (de)
CZ (2) CZ294168B6 (de)
DE (5) DE29522153U1 (de)
DK (4) DK0978276T3 (de)
DZ (1) DZ1876A1 (de)
ES (4) ES2182754T3 (de)
FI (1) FI964249A (de)
GB (1) GB9408117D0 (de)
GR (2) GR3035031T3 (de)
HK (5) HK1027024A1 (de)
HU (1) HU228399B1 (de)
IL (1) IL113433A (de)
MA (1) MA23528A1 (de)
MY (1) MY115351A (de)
NO (1) NO310703B1 (de)
NZ (1) NZ285080A (de)
OA (1) OA10377A (de)
PL (1) PL316966A1 (de)
PT (4) PT761218E (de)
RO (1) RO116997B1 (de)
RU (1) RU2152213C1 (de)
SA (1) SA95160343B1 (de)
SI (1) SI0758235T1 (de)
SK (1) SK282594B6 (de)
WO (1) WO1995028927A1 (de)
ZA (1) ZA953236B (de)

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* Cited by examiner, † Cited by third party
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US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
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AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
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US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
CN1194687C (zh) * 1997-02-14 2005-03-30 史密斯克莱恩比彻姆药物实验室 含有阿莫西林和克拉维酸盐的药物制剂
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ES2215628T5 (es) 1999-04-01 2011-11-28 Dsm Ip Assets B.V. Aglomerados obtenidos por cristalización.
AU767177B2 (en) * 1999-04-13 2003-11-06 Beecham Pharmaceuticals (Pte) Limited Novel method of treatment
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
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US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
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US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
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US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
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CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
CN102596184B (zh) * 2009-09-18 2015-03-11 赛诺菲 稳定性提高的(z)-2-氰基-3-羟基-丁-2-烯酸-(4’-三氟甲基苯基)-酰胺片剂制剂
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair

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GB1241844A (en) 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
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NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
EP0080862B1 (de) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmazeutische Zubereitung die Beta-Lactam Antibiotika enthält
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
AU767177B2 (en) * 1999-04-13 2003-11-06 Beecham Pharmaceuticals (Pte) Limited Novel method of treatment
EP1330236A2 (de) * 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Amoxicillinhaltige arzneizusammensetzungen

Also Published As

Publication number Publication date
AP564A (en) 1996-11-21
ATE223706T1 (de) 2002-09-15
DE69521799T2 (de) 2002-06-13
SA95160343B1 (ar) 2005-05-04
DE69519093T2 (de) 2001-07-19
EP0758235A1 (de) 1997-02-19
EP1093813A3 (de) 2001-05-30
DE69528204T2 (de) 2003-08-07
AU2406895A (en) 1995-11-16
FI964249A0 (fi) 1996-10-22
FI964249A (fi) 1996-10-22
SK135496A3 (en) 1997-05-07
JPH09512027A (ja) 1997-12-02
HK1009936A1 (en) 1999-06-11
ATE203161T1 (de) 2001-08-15
GB9408117D0 (en) 1994-06-15
AT5350U1 (de) 2002-06-25
PL316966A1 (en) 1997-03-03
CN1134258C (zh) 2004-01-14
NZ285080A (en) 1998-05-27
DK1093813T3 (da) 2003-02-17
CA2188496A1 (en) 1995-11-02
GR3036844T3 (en) 2002-01-31
EP0978276A2 (de) 2000-02-09
ATE226074T1 (de) 2002-11-15
US6051255A (en) 2000-04-18
IL113433A0 (en) 1995-07-31
EP0978276A3 (de) 2000-04-12
CZ309096A3 (en) 1997-04-16
HU228399B1 (en) 2013-03-28
PT758235E (pt) 2001-10-31
MA23528A1 (fr) 1995-12-31
SI0758235T1 (en) 2001-10-31
NO964488D0 (no) 1996-10-22
EP0758235B1 (de) 2001-07-18
RO116997B1 (ro) 2001-09-28
DE69528608D1 (de) 2002-11-21
AP9500733A0 (en) 1995-04-30
AP9600868A0 (en) 1996-10-31
WO1995028927A1 (en) 1995-11-02
AU684949B2 (en) 1998-01-08
HK1027024A1 (en) 2001-01-05
DK0978276T3 (da) 2003-01-20
ZA953236B (en) 1995-12-27
CN1149829A (zh) 1997-05-14
HU9602922D0 (en) 1996-12-30
HK1050992A1 (zh) 2003-07-18
ES2161288T3 (es) 2001-12-01
MY115351A (en) 2003-05-31
DZ1876A1 (fr) 2002-02-17
ES2152485T3 (es) 2001-02-01
AT5349U1 (de) 2002-06-25
ES2180251T3 (es) 2003-02-01
JP3622975B2 (ja) 2005-02-23
EP0761218B1 (de) 2000-10-11
BG62842B1 (bg) 2000-09-29
HK1021860A1 (en) 2000-07-07
EP0978276B1 (de) 2002-09-11
EP1243267A2 (de) 2002-09-25
DK0761218T3 (da) 2000-12-18
EP0761218A1 (de) 1997-03-12
RU2152213C1 (ru) 2000-07-10
PT978276E (pt) 2003-01-31
PT761218E (pt) 2001-03-30
DE29522153U1 (de) 2000-04-06
GR3035031T3 (en) 2001-03-30
ES2182754T3 (es) 2003-03-16
CZ294168B6 (cs) 2004-10-13
HUT76335A (en) 1997-08-28
HK1036404A1 (en) 2002-01-04
BR9507502A (pt) 1997-09-02
EP1093813A2 (de) 2001-04-25
EP1093813B1 (de) 2002-10-16
CZ11376U1 (cs) 2001-07-12
DE69521799D1 (de) 2001-08-23
NO310703B1 (no) 2001-08-20
IL113433A (en) 2003-06-24
DE69519093D1 (de) 2000-11-16
SK282594B6 (sk) 2002-10-08
OA10377A (en) 2001-11-21
EP1243267A3 (de) 2002-10-30
NO964488L (no) 1996-12-17
DE69528608T2 (de) 2003-06-26
DK0758235T3 (da) 2001-10-29
DE69528204D1 (de) 2002-10-17
BG100933A (en) 1997-07-31
PT1093813E (pt) 2003-02-28

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