BG62842B1 - Таблетки, съдържащи амоксицилин и клавулант, с полимернопокритие - Google Patents

Таблетки, съдържащи амоксицилин и клавулант, с полимернопокритие Download PDF

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Publication number
BG62842B1
BG62842B1 BG100933A BG10093396A BG62842B1 BG 62842 B1 BG62842 B1 BG 62842B1 BG 100933 A BG100933 A BG 100933A BG 10093396 A BG10093396 A BG 10093396A BG 62842 B1 BG62842 B1 BG 62842B1
Authority
BG
Bulgaria
Prior art keywords
tablet
clavulanate
amoxicillin
weight
formulation according
Prior art date
Application number
BG100933A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100933A (en
Inventor
Creighton P. Conley
Nigel P. Davidson
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG62842(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of BG100933A publication Critical patent/BG100933A/xx
Publication of BG62842B1 publication Critical patent/BG62842B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG100933A 1994-04-23 1996-10-23 Таблетки, съдържащи амоксицилин и клавулант, с полимернопокритие BG62842B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations
PCT/EP1995/001463 WO1995028927A1 (en) 1994-04-23 1995-04-19 Polymer coated tablet comprising amoxycillin and clavulanate

Publications (2)

Publication Number Publication Date
BG100933A BG100933A (en) 1997-07-31
BG62842B1 true BG62842B1 (bg) 2000-09-29

Family

ID=10754044

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100933A BG62842B1 (bg) 1994-04-23 1996-10-23 Таблетки, съдържащи амоксицилин и клавулант, с полимернопокритие

Country Status (35)

Country Link
US (1) US6051255A (de)
EP (5) EP0978276B1 (de)
JP (1) JP3622975B2 (de)
CN (1) CN1134258C (de)
AP (2) AP564A (de)
AT (6) ATE203161T1 (de)
AU (1) AU684949B2 (de)
BG (1) BG62842B1 (de)
BR (1) BR9507502A (de)
CA (1) CA2188496A1 (de)
CZ (2) CZ11376U1 (de)
DE (5) DE29522153U1 (de)
DK (4) DK0761218T3 (de)
DZ (1) DZ1876A1 (de)
ES (4) ES2152485T3 (de)
FI (1) FI964249A0 (de)
GB (1) GB9408117D0 (de)
GR (2) GR3035031T3 (de)
HK (5) HK1036404A1 (de)
HU (1) HU228399B1 (de)
IL (1) IL113433A (de)
MA (1) MA23528A1 (de)
MY (1) MY115351A (de)
NO (1) NO310703B1 (de)
NZ (1) NZ285080A (de)
OA (1) OA10377A (de)
PL (1) PL316966A1 (de)
PT (4) PT978276E (de)
RO (1) RO116997B1 (de)
RU (1) RU2152213C1 (de)
SA (1) SA95160343B1 (de)
SI (1) SI0758235T1 (de)
SK (1) SK282594B6 (de)
WO (1) WO1995028927A1 (de)
ZA (1) ZA953236B (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
WO1997009042A1 (en) * 1995-09-07 1997-03-13 Smithkline Beecham Corporation Pharmaceutical formulation
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
PL334976A1 (en) * 1997-02-14 2000-03-27 Smithkline Beecham Lab Pharmaceutic preparations containing amoxycyclin and clavulate
TR200000529T2 (tr) * 1997-08-29 2000-08-21 Dsm N.V. İçinde eksipiyan olmayan granüller
CA2307887A1 (en) 1997-10-31 1999-05-14 Monsanto Company Gellan gum tablet coating
CA2364342C (en) 1999-04-01 2011-02-01 Dsm N.V. Agglomerates by crystallisation
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
MXPA01010377A (es) * 1999-04-13 2002-10-23 Beecham Pharm Pte Ltd Metodo novedoso de tratamiento.
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
WO2002002081A1 (en) * 2000-07-05 2002-01-10 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and methods of using same
EP1330236A2 (de) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Amoxicillinhaltige arzneizusammensetzungen
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
WO2003066053A1 (en) * 2002-02-07 2003-08-14 Rutgers, The State University Antibiotic polymers
GB0203528D0 (en) * 2002-02-14 2002-04-03 Glaxo Group Ltd Process and composition
MXPA04007857A (es) * 2002-02-14 2004-10-15 Glaxo Group Ltd Composicion farmaceutica que comprende n-((1-butil -4-piperidinil) metil)-3, 4-dihidro-2h -(1, 3)oxazino (3, 2-a)indol -10-carboxamida o sal de la misma, y procedimiento para la misma que comprende granulacion en seco.
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
KR100456833B1 (ko) * 2002-08-01 2004-11-10 주식회사 대웅 아목시실린 및 클라불라네이트를 함유하는 유핵정
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
CA2406592C (en) * 2002-10-04 2003-09-30 Duchesnay Inc. Method of preparing pharmaceutical dosage forms containing multiple active ingredients
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
AU2004258944B2 (en) * 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2533292C (en) 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
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JP2007502296A (ja) * 2003-08-11 2007-02-08 アドバンシス ファーマスーティカル コーポレイション ロバストペレット
US8062672B2 (en) * 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
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DE10341264A1 (de) * 2003-09-04 2005-03-24 Grünenthal GmbH Schmelzformulierte, multipartikuläre orale Darreichungsform
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KR100780553B1 (ko) * 2005-08-18 2007-11-29 한올제약주식회사 메트포르민 서방정 및 그의 제조방법
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
PE20121478A1 (es) * 2009-09-18 2012-11-12 Sanofi Sa Formulaciones en comprimido de teriflunomida: "(4'-trifluorometilfenil) amida del acido (z)-2-ciano-3-hidroxibut-2-enoico con estabilidad mejorada
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241844A (en) 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
US4098897A (en) * 1975-04-14 1978-07-04 Beecham Group Limited Anti bacterial agents
JO984B1 (en) 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
EP0080862B1 (de) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmazeutische Zubereitung die Beta-Lactam Antibiotika enthält
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
MXPA01010377A (es) * 1999-04-13 2002-10-23 Beecham Pharm Pte Ltd Metodo novedoso de tratamiento.
EP1330236A2 (de) * 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Amoxicillinhaltige arzneizusammensetzungen

Also Published As

Publication number Publication date
GR3035031T3 (en) 2001-03-30
SI0758235T1 (en) 2001-10-31
WO1995028927A1 (en) 1995-11-02
MA23528A1 (fr) 1995-12-31
EP1093813A2 (de) 2001-04-25
HK1027024A1 (en) 2001-01-05
PT1093813E (pt) 2003-02-28
EP1243267A2 (de) 2002-09-25
PL316966A1 (en) 1997-03-03
BG100933A (en) 1997-07-31
ES2152485T3 (es) 2001-02-01
PT758235E (pt) 2001-10-31
HK1021860A1 (en) 2000-07-07
JP3622975B2 (ja) 2005-02-23
EP0978276A3 (de) 2000-04-12
FI964249A (fi) 1996-10-22
DE29522153U1 (de) 2000-04-06
CN1149829A (zh) 1997-05-14
HK1050992A1 (zh) 2003-07-18
DE69528608D1 (de) 2002-11-21
EP1093813A3 (de) 2001-05-30
SK282594B6 (sk) 2002-10-08
NZ285080A (en) 1998-05-27
SA95160343B1 (ar) 2005-05-04
AP9600868A0 (en) 1996-10-31
HUT76335A (en) 1997-08-28
DE69519093D1 (de) 2000-11-16
EP0978276B1 (de) 2002-09-11
EP0758235A1 (de) 1997-02-19
DK0978276T3 (da) 2003-01-20
EP1093813B1 (de) 2002-10-16
AT5349U1 (de) 2002-06-25
ATE223706T1 (de) 2002-09-15
EP0978276A2 (de) 2000-02-09
CA2188496A1 (en) 1995-11-02
ES2182754T3 (es) 2003-03-16
ES2161288T3 (es) 2001-12-01
DE69519093T2 (de) 2001-07-19
HU228399B1 (en) 2013-03-28
HK1036404A1 (en) 2002-01-04
DE69521799D1 (de) 2001-08-23
AP564A (en) 1996-11-21
IL113433A0 (en) 1995-07-31
DE69528608T2 (de) 2003-06-26
EP1243267A3 (de) 2002-10-30
PT978276E (pt) 2003-01-31
OA10377A (en) 2001-11-21
DE69528204D1 (de) 2002-10-17
HK1009936A1 (en) 1999-06-11
AU2406895A (en) 1995-11-16
ATE203161T1 (de) 2001-08-15
FI964249A0 (fi) 1996-10-22
EP0758235B1 (de) 2001-07-18
GR3036844T3 (en) 2002-01-31
EP0761218B1 (de) 2000-10-11
ATE196845T1 (de) 2000-10-15
CZ11376U1 (cs) 2001-07-12
PT761218E (pt) 2001-03-30
AT5350U1 (de) 2002-06-25
MY115351A (en) 2003-05-31
ES2180251T3 (es) 2003-02-01
DK1093813T3 (da) 2003-02-17
NO964488L (no) 1996-12-17
HU9602922D0 (en) 1996-12-30
RO116997B1 (ro) 2001-09-28
GB9408117D0 (en) 1994-06-15
SK135496A3 (en) 1997-05-07
DK0761218T3 (da) 2000-12-18
EP0761218A1 (de) 1997-03-12
CZ294168B6 (cs) 2004-10-13
AU684949B2 (en) 1998-01-08
DE69528204T2 (de) 2003-08-07
NO964488D0 (no) 1996-10-22
JPH09512027A (ja) 1997-12-02
CN1134258C (zh) 2004-01-14
AP9500733A0 (en) 1995-04-30
CZ309096A3 (en) 1997-04-16
DZ1876A1 (fr) 2002-02-17
ATE226074T1 (de) 2002-11-15
US6051255A (en) 2000-04-18
DE69521799T2 (de) 2002-06-13
DK0758235T3 (da) 2001-10-29
RU2152213C1 (ru) 2000-07-10
ZA953236B (en) 1995-12-27
IL113433A (en) 2003-06-24
NO310703B1 (no) 2001-08-20
BR9507502A (pt) 1997-09-02

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