AR068722A1 - Metodo para la produccion de metionina, sus derivados o precursores a partir de un proceso fermentativo - Google Patents

Metodo para la produccion de metionina, sus derivados o precursores a partir de un proceso fermentativo

Info

Publication number
AR068722A1
AR068722A1 ARP080104317A ARP080104317A AR068722A1 AR 068722 A1 AR068722 A1 AR 068722A1 AR P080104317 A ARP080104317 A AR P080104317A AR P080104317 A ARP080104317 A AR P080104317A AR 068722 A1 AR068722 A1 AR 068722A1
Authority
AR
Argentina
Prior art keywords
microorganism
production
methionine
precursors
derivatives
Prior art date
Application number
ARP080104317A
Other languages
English (en)
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of AR068722A1 publication Critical patent/AR068722A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/0101—Formyltetrahydrofolate deformylase (3.5.1.10)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Abstract

También se proporciona un microorganismo modificado de acuerdo al método descripto. Reivindicacion 1: Un método para la produccion de metionina, sus derivados, o precursores en un proceso fermentativo que comprende las siguientes etapas: cultivo de un microorganismo en un medio de cultivo apropiado que comprende una fuente de carbono y una fuente de azufre, y recuperacion de la metionina del medio de cultivo, donde, comparado con un microorganismo y/o método no modificado, el microorganismo y/o método ha sido modificado para presentar un aumento del rendimiento de la metionina/fuente de carbono con por lo menos una de las siguientes modificaciones o combinaciones, a saber: disminuyendo, en el microorganismo, la deformilacion del formal-THF, disminuyendo el consumo de PEP en el microorganismo, limitando el crecimiento y produccion de biomasa de los microorganismos modificados limitando o privando al microorganismo de uno o varios de los sustrato(s) inorgánicos en el medio de cultivo.
ARP080104317A 2007-10-02 2008-10-02 Metodo para la produccion de metionina, sus derivados o precursores a partir de un proceso fermentativo AR068722A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2007/060433 WO2009043372A1 (en) 2007-10-02 2007-10-02 Increasing methionine yield

Publications (1)

Publication Number Publication Date
AR068722A1 true AR068722A1 (es) 2009-12-02

Family

ID=39521485

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080104317A AR068722A1 (es) 2007-10-02 2008-10-02 Metodo para la produccion de metionina, sus derivados o precursores a partir de un proceso fermentativo

Country Status (16)

Country Link
US (2) US20100248311A1 (es)
EP (2) EP2205754B1 (es)
JP (1) JP5701604B2 (es)
KR (2) KR101636662B1 (es)
CN (2) CN101821401B (es)
AR (1) AR068722A1 (es)
BR (1) BRPI0818528B1 (es)
DK (2) DK2205754T3 (es)
ES (2) ES2557487T3 (es)
HR (1) HRP20160075T1 (es)
HU (2) HUE030032T2 (es)
MX (1) MX2010003609A (es)
MY (2) MY170749A (es)
PL (2) PL2573189T3 (es)
RU (1) RU2010115225A (es)
WO (2) WO2009043372A1 (es)

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Also Published As

Publication number Publication date
EP2205754B1 (en) 2015-11-04
CN101821401B (zh) 2013-10-30
WO2009043372A1 (en) 2009-04-09
KR101636662B1 (ko) 2016-07-05
WO2009043803A3 (en) 2009-06-18
HUE030032T2 (en) 2017-04-28
ES2600036T3 (es) 2017-02-06
EP2205754A2 (en) 2010-07-14
KR101586098B1 (ko) 2016-01-19
MY180720A (en) 2020-12-07
US20160160249A1 (en) 2016-06-09
KR20100075587A (ko) 2010-07-02
CN103087971B (zh) 2016-12-28
US10858679B2 (en) 2020-12-08
MY170749A (en) 2019-08-27
DK2205754T3 (en) 2015-12-21
US20100248311A1 (en) 2010-09-30
EP2573189B1 (en) 2016-08-03
HUE026672T2 (en) 2016-07-28
JP5701604B2 (ja) 2015-04-15
DK2573189T3 (en) 2016-09-26
BRPI0818528A8 (pt) 2017-09-19
ES2557487T3 (es) 2016-01-26
HRP20160075T1 (hr) 2016-02-12
WO2009043803A2 (en) 2009-04-09
PL2573189T3 (pl) 2017-01-31
MX2010003609A (es) 2010-04-30
EP2573189A1 (en) 2013-03-27
BRPI0818528B1 (pt) 2023-01-17
RU2010115225A (ru) 2011-11-10
CN101821401A (zh) 2010-09-01
PL2205754T3 (pl) 2016-04-29
BRPI0818528A2 (pt) 2016-07-26
KR20150038696A (ko) 2015-04-08
JP2010539962A (ja) 2010-12-24
CN103087971A (zh) 2013-05-08

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