AR027034A1 - Composicion para dosis oral de liberacion extendida - Google Patents

Composicion para dosis oral de liberacion extendida

Info

Publication number
AR027034A1
AR027034A1 ARP000106791A ARP000106791A AR027034A1 AR 027034 A1 AR027034 A1 AR 027034A1 AR P000106791 A ARP000106791 A AR P000106791A AR P000106791 A ARP000106791 A AR P000106791A AR 027034 A1 AR027034 A1 AR 027034A1
Authority
AR
Argentina
Prior art keywords
composition
extended release
oral extended
release dose
pharmaceutically acceptable
Prior art date
Application number
ARP000106791A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22629073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR027034(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of AR027034A1 publication Critical patent/AR027034A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe una composicion solida bicapa comprimida que comprende (a) una primer capa de liberacion inmediata que comprende una cantidad anti-alérgicaefectiva de desloratina y al menos una excipiente farmacéuticamente aceptable y (b) una segunda cap a de liberacion sostenida de una cantidad efectiva de undescongestivo nasal y un agente de liberacion sostenida farmacéuticamente aceptable donde la composicion contiene menos del 2% de productos de ladescomposicion de la desloratadina.
ARP000106791A 1999-12-20 2000-12-20 Composicion para dosis oral de liberacion extendida AR027034A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17275299P 1999-12-20 1999-12-20

Publications (1)

Publication Number Publication Date
AR027034A1 true AR027034A1 (es) 2003-03-12

Family

ID=22629073

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000106791A AR027034A1 (es) 1999-12-20 2000-12-20 Composicion para dosis oral de liberacion extendida

Country Status (39)

Country Link
US (3) US6709676B2 (es)
EP (3) EP1674084B1 (es)
JP (2) JP5158919B2 (es)
KR (2) KR20010062543A (es)
CN (3) CN100415223C (es)
AR (1) AR027034A1 (es)
AT (2) ATE329584T1 (es)
AU (2) AU2276801A (es)
BR (1) BR0005938A (es)
CA (1) CA2329172C (es)
CO (1) CO5251421A1 (es)
CY (3) CY1105231T1 (es)
CZ (1) CZ302471B6 (es)
DE (3) DE60042904D1 (es)
DK (2) DK1674084T3 (es)
EC (1) ECSP003835A (es)
ES (2) ES2261158T3 (es)
FR (1) FR08C0004I2 (es)
HK (2) HK1034452A1 (es)
HU (1) HU227538B1 (es)
IL (1) IL140451A (es)
LU (1) LU91403I2 (es)
MX (1) MXPA00012957A (es)
MY (1) MY128658A (es)
NL (1) NL300328I2 (es)
NO (1) NO331653B1 (es)
NZ (1) NZ509034A (es)
PE (1) PE20010952A1 (es)
PL (1) PL209401B1 (es)
PT (2) PT1674084E (es)
RU (1) RU2284182C9 (es)
SA (2) SA06270068B1 (es)
SG (2) SG183573A1 (es)
SI (2) SI1674084T1 (es)
SK (1) SK287105B6 (es)
TR (1) TR200003788A2 (es)
TW (1) TWI222885B (es)
WO (1) WO2001045676A2 (es)
ZA (1) ZA200007714B (es)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287105B6 (sk) * 1999-12-20 2009-12-07 Schering Corporation Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním
AU2277101A (en) * 1999-12-20 2001-07-03 Schering Corporation Stable extended release oral dosage composition
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
JP4318899B2 (ja) * 2001-08-27 2009-08-26 第一三共ヘルスケア株式会社 抗感冒剤
JP2009132734A (ja) * 2001-08-27 2009-06-18 Daiichi Sankyo Healthcare Co Ltd 抗感冒剤
JP4320217B2 (ja) * 2002-07-10 2009-08-26 剤盛堂薬品株式会社 鼻炎用経口製剤
AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
DE602004004453T2 (de) * 2003-03-12 2007-11-08 Teva Pharmaceutical Industries Ltd. Stabile pharmazeutische zusammensetzungen mit desloratadin
WO2005046650A1 (en) * 2003-11-12 2005-05-26 Glenmark Pharmaceuticals Limited Pharmaceutical formulation containing muscle relaxant and cox-ii inhibitor
WO2005065047A2 (en) * 2003-12-23 2005-07-21 Sun Pharmaceutical Industries Limited Stable oral composition containing desloratadine
EP1859791B1 (en) * 2005-03-10 2011-12-07 Taisho Pharmaceutical Co., Ltd Sugar-coated tablet
US20110081415A1 (en) * 2005-03-10 2011-04-07 Taisho Pharmaceutical Co., Ltd Coating apparatus
US20060252830A1 (en) * 2005-05-06 2006-11-09 Brandon Stephen F Method for the treatment of magnesium and potassium deficiencies
US20060252831A1 (en) * 2005-05-06 2006-11-09 Christopher Offen Method for the treatment of magnesium and potassium deficiencies
EP1728513A3 (en) * 2005-05-20 2007-10-31 Dr. Reddy's Laboratories, Inc. Stable desloratadine compositions
US20070004671A1 (en) * 2005-05-20 2007-01-04 Agarwal Sudeep K Stable desloratadine compositions
US20070014855A1 (en) * 2005-07-12 2007-01-18 Rahul Gawande S Stable desloratadine compositions
JP5269595B2 (ja) 2005-09-09 2013-08-21 アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー １日１回投与用トラゾドン組成物
US20080103746A1 (en) * 2005-11-30 2008-05-01 Searete Llc, A Limited Liability Corporation Systems and methods for pathogen detection and response
US20080033763A1 (en) * 2005-11-30 2008-02-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems related to receiving nutraceutical associated information
US20070124219A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized nutraceutical selection and packaging
US20110145009A1 (en) * 2005-11-30 2011-06-16 Jung Edward K Y Methods and systems related to transmission of nutraceutical associatd information
US8340944B2 (en) * 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US20080052114A1 (en) * 2005-11-30 2008-02-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems and methods related to nutraceuticals
US8297028B2 (en) 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US20070289258A1 (en) * 2006-06-14 2007-12-20 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Individualized pharmaceutical selection and packaging
US8000981B2 (en) 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US20080004905A1 (en) * 2006-06-28 2008-01-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for analysis of nutraceutical associated components
US7927787B2 (en) * 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
US20070136092A1 (en) * 2005-11-30 2007-06-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
US10296720B2 (en) * 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US7827042B2 (en) * 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US7974856B2 (en) 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US20070174128A1 (en) * 2005-11-30 2007-07-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
US20080114577A1 (en) * 2005-11-30 2008-05-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational methods and systems associated with nutraceutical related assays
US20070124176A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems and methods related to nutraceutical agent selection and dosing
WO2007096733A2 (en) * 2006-02-22 2007-08-30 Orchid Chemicals & Pharmaceuticals Limited Desloratadine-containing formulation stabilized with cyclodextrin
CA2541045A1 (en) * 2006-03-24 2007-09-24 Pharmascience Inc. A descarbonylethoxyloratadine containing pharmaceutical composition
KR101464771B1 (ko) * 2006-06-01 2014-11-26 머크 샤프 앤드 돔 코포레이션 페닐에프린의 지속 방출용 약제학적 조성물
WO2007143158A2 (en) 2006-06-01 2007-12-13 Schering-Plough Healthcare Products, Inc. Sustained release pharmaceutical formulation comprising phenylephrine
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
RU2008151945A (ru) * 2006-06-01 2010-07-20 Шеринг Корпорейшн (US) Лекарственные формы с пульсирующим высвобождением и фармацевтические композиции фенилэфрина
US7718649B1 (en) * 2006-11-10 2010-05-18 Pisgah Labs, Inc. Physical states of a pharmaceutical drug substance
CN101848706A (zh) * 2007-06-01 2010-09-29 先灵-普劳健康护理产品公司 包含底物和含活性成分和聚乙烯醇的包衣的药用组合物
TWI400042B (zh) * 2007-06-08 2013-07-01 Tci Co Ltd 食品錠劑
ES2541809T3 (es) 2007-10-16 2015-07-24 Paladin Labs Inc. Composición bicapa para la liberación sostenida de acetaminofeno y tramadol
PE20091084A1 (es) * 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
EP2219612A4 (en) 2007-12-17 2013-10-30 Paladin Labs Inc CONTROLLED RELEASE FORMULATION AVOIDING IMPROPER USES
EP2367541B1 (en) 2008-12-16 2014-07-16 Paladin Labs Inc. Misuse preventative, controlled release formulation
WO2012151562A1 (en) 2011-05-04 2012-11-08 Intellikine, Llc Combination pharmaceutical compositions and uses thereof
BR102012030828A2 (pt) 2012-12-03 2014-09-16 Ems Sa Composição farmacêutica compreendendo desloratadina e prednisolona e seu uso
US10576041B2 (en) 2016-09-26 2020-03-03 The Procter & Gamble Company Extended relief dosage form
US20180187263A1 (en) 2017-01-05 2018-07-05 Iowa State University Research Foundation, Inc. Kits for diagnostic detection and prevention of feedlot bovine respiratory disease
CN109966254B (zh) * 2017-12-28 2021-06-01 广州医药研究总院有限公司 复方地氯伪麻缓释小丸及其制备方法
CN108578406A (zh) * 2018-04-18 2018-09-28 曹建华 一种用于过敏性鼻炎治疗的组合物
WO2021168133A1 (en) * 2020-02-19 2021-08-26 Nevakar Inc. Isoproterenol compositions and methods
CN113230235B (zh) * 2021-04-15 2022-11-11 海南普利制药股份有限公司 含地氯雷他定的复方缓释胶囊及其制备方法

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3940485A (en) 1973-12-12 1976-02-24 Levinson Harold N Treatment and pre-treatment of dysmetric dyslexia by improving sequential scanning and ocular fixation abilities and therapeutic compounds
US4008796A (en) 1974-03-26 1977-02-22 General Concrete Of Canada Limited Control method for feeding items on a conveyor
GB1548022A (en) 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
US4282233B1 (en) 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
AU570306B2 (en) 1984-02-15 1988-03-10 Schering Corporation 8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridine and its salts.
US4552899A (en) 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4783465A (en) 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
SE8404467D0 (sv) 1984-09-06 1984-09-06 Ferrosan Ab Controlled-release medical preparations
US4731447A (en) 1985-05-13 1988-03-15 Schering Corporation Process for preparing piperidylidene dihydro-dibenzo(a,d)-cycloheptenes or aza-derivatives thereof
US4804666A (en) 1985-08-14 1989-02-14 Schering Corporation Antiallergic 6,11-dihydro-11-(4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines
JPS6396126A (ja) 1986-10-13 1988-04-27 Taisho Pharmaceut Co Ltd 安定化組成物
US5089496A (en) 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
US4777170A (en) 1987-02-03 1988-10-11 Heinrich William A Method to prevent and treat the signs and symptoms of motion sickness
GB8707421D0 (en) 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
US4863931A (en) 1988-09-15 1989-09-05 Schering Corporation Antihistaminic fluoro substituted benzocycloheptapyridines
US5019591A (en) 1989-02-17 1991-05-28 Pennsylvania Research Corporation Method for treating retinopathy and other small vessel disorders associated with diabetes
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
IE68935B1 (en) 1990-06-22 1996-07-24 Schering Corp Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use
CA2098198A1 (en) 1990-12-18 1992-06-18 Ann Christie King Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
PT100502A (pt) 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol
YU48263B (sh) * 1991-06-17 1997-09-30 Byk Gulden Lomberg Chemische Fabrik Gmbh. Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
JP2646972B2 (ja) 1993-11-01 1997-08-27 日本電気株式会社 多ビットメモリ
DE4442999A1 (de) 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
US5595997A (en) 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
US7211582B1 (en) * 1994-12-30 2007-05-01 Sepracor Inc. Methods for treating urticaria using descarboethoxyloratadine
US7214683B1 (en) * 1994-12-30 2007-05-08 Sepracor Inc. Compositions of descarboethoxyloratadine
PE11399A1 (es) * 1996-10-31 1999-02-09 Schering Corp Combinacion de loratadina y un descongestionante para el tratamiento del asma
PE71699A1 (es) * 1997-02-07 1999-08-03 Sepracor Inc Composicion farmaceutica de descarboetoxiloratadina sin lactosa, no higroscopica y anhidra
US5900421A (en) 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
US5939426A (en) 1997-02-28 1999-08-17 Sepracor Inc. Methods for treating urinary incontinence using descarboethoxyloratadine
US6506767B1 (en) 1997-07-02 2003-01-14 Schering Corporation 8-chloro-6,11-dihydro-11-(4-piperidylidine)-5H-benzo[5,6]cyclohepta[1-2-b] pyridine
IL133420A (en) * 1997-08-26 2004-07-25 Aventis Pharma Inc Tablet-shaped pharmaceutical preparation containing a combination of piperidinoalkanol and antihistamines and reduces symptomatic congestion
WO1999021556A1 (en) 1997-10-29 1999-05-06 J-Med Pharmaceuticals, Inc. Antihistamine/decongestant regimens for treating rhinitis
US6132758A (en) * 1998-06-01 2000-10-17 Schering Corporation Stabilized antihistamine syrup
IL139407A0 (en) * 1998-07-10 2001-11-25 Schering Corp 8-CHLORO-6, 11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO [5,6] CYCLOHEPTA [1, 2-b] PYRIDINE ORAL COMPOSITIONS
US6423721B1 (en) * 1998-09-10 2002-07-23 Schering Corporation Methods and compositions for treating sinusitis, otitis media and other related disorders using antihistamines
US6051585A (en) 1998-12-07 2000-04-18 Weinstein; Robert E. Single-dose antihistamine/decongestant formulations for treating rhinitis
US6521254B2 (en) 1998-12-07 2003-02-18 J-Med Pharmaceuticals, Inc. Single-dose antihistamine/decongestant formulations for treating rhinitis
US6100274A (en) 1999-07-07 2000-08-08 Schering Corporation 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
US6114346A (en) * 1999-10-22 2000-09-05 Schering Corporation Treating sleep disorders using desloratadine
SK287105B6 (sk) * 1999-12-20 2009-12-07 Schering Corporation Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním
AU2277101A (en) 1999-12-20 2001-07-03 Schering Corporation Stable extended release oral dosage composition
MXPA02007558A (es) * 2000-02-03 2002-12-13 Schering Corp Tratamiento de condiciones inflamatorias alergicas.
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
EP1289945B1 (en) * 2000-05-19 2004-08-04 Alcon Inc. Aniline disulfide derivatives for treating allergic diseases
US6599913B1 (en) 2001-06-29 2003-07-29 Schering Corporation Treating allergic and inflammatory conditions
US6679463B1 (en) * 2003-06-11 2004-01-20 Kye Systems Corp. Support with multi-stage clamping mechanism
WO2005065047A2 (en) * 2003-12-23 2005-07-21 Sun Pharmaceutical Industries Limited Stable oral composition containing desloratadine
NZ552998A (en) * 2004-07-16 2010-11-26 Cipla Ltd Anti-histaminic composition

Also Published As

Publication number Publication date
CA2329172C (en) 2005-10-25
HUP0004989A2 (hu) 2004-05-28
IL140451A0 (en) 2002-02-10
NO20006503D0 (no) 2000-12-20
NL300328I2 (nl) 2008-07-01
PT1110543E (pt) 2006-08-31
DE60042904D1 (de) 2009-10-15
WO2001045676A2 (en) 2001-06-28
HU0004989D0 (es) 2001-02-28
SA06270068B1 (ar) 2009-12-23
FR08C0004I1 (es) 2008-03-21
MXPA00012957A (es) 2003-06-19
DK1110543T3 (da) 2006-09-18
CO5251421A1 (es) 2003-02-28
ECSP003835A (es) 2002-02-25
EP1674084A2 (en) 2006-06-28
TWI222885B (en) 2004-11-01
LU91403I2 (fr) 2008-02-21
HK1090840A1 (en) 2007-01-05
PE20010952A1 (es) 2001-09-25
US20040097536A1 (en) 2004-05-20
CZ20004813A3 (cs) 2001-08-15
NZ509034A (en) 2002-09-27
NO331653B1 (no) 2012-02-13
US20100021542A1 (en) 2010-01-28
US6709676B2 (en) 2004-03-23
IL140451A (en) 2011-11-30
ES2330873T3 (es) 2009-12-16
CN101134038A (zh) 2008-03-05
SI1110543T1 (sl) 2006-10-31
EP1674084B1 (en) 2009-09-02
SK287105B6 (sk) 2009-12-07
BR0005938A (pt) 2001-11-27
CY2007031I1 (el) 2009-11-04
SA01210740A (ar) 2005-12-03
SI1674084T1 (sl) 2010-01-29
AU7244200A (en) 2001-06-21
US8187630B2 (en) 2012-05-29
FR08C0004I2 (fr) 2009-01-15
RU2284182C9 (ru) 2007-11-20
EP1110543A3 (en) 2001-08-29
HUP0004989A3 (en) 2008-04-28
CN1302605A (zh) 2001-07-11
EP1674084A3 (en) 2006-07-05
CN101134038B (zh) 2013-11-06
WO2001045676A3 (en) 2002-01-03
TR200003788A3 (tr) 2001-07-23
CY2007031I2 (el) 2009-11-04
SK19662000A3 (sk) 2001-09-11
CN101322708A (zh) 2008-12-17
AU777419B2 (en) 2004-10-14
TR200003788A2 (tr) 2001-07-23
DK1674084T3 (da) 2009-12-14
JP5158919B2 (ja) 2013-03-06
DE60028710D1 (de) 2006-07-27
PL209401B1 (pl) 2011-08-31
CN100415223C (zh) 2008-09-03
HU227538B1 (en) 2011-08-29
KR20010062543A (ko) 2001-07-07
ES2261158T3 (es) 2006-11-16
JP2001206846A (ja) 2001-07-31
PT1674084E (pt) 2009-10-19
CY1105231T1 (el) 2010-03-03
NO20006503L (no) 2001-06-21
ATE441404T1 (de) 2009-09-15
KR20080044214A (ko) 2008-05-20
HK1034452A1 (en) 2001-10-26
DE60028710T2 (de) 2007-06-14
MY128658A (en) 2007-02-28
SG183573A1 (en) 2012-09-27
US7618649B2 (en) 2009-11-17
EP2100600A1 (en) 2009-09-16
CY1109636T1 (el) 2014-08-13
EP1110543A2 (en) 2001-06-27
JP2008081509A (ja) 2008-04-10
CA2329172A1 (en) 2001-06-20
NL300328I1 (nl) 2008-03-03
ATE329584T1 (de) 2006-07-15
EP1110543B1 (en) 2006-06-14
RU2284182C2 (ru) 2006-09-27
DE122008000001I1 (de) 2008-04-17
CZ302471B6 (cs) 2011-06-08
PL344714A1 (en) 2001-07-02
US20030031713A1 (en) 2003-02-13
ZA200007714B (en) 2001-08-16
AU2276801A (en) 2001-07-03
SA01210740B1 (ar) 2006-10-31
SG149667A1 (en) 2009-02-27

Similar Documents

Publication Publication Date Title
AR027034A1 (es) Composicion para dosis oral de liberacion extendida
ES2157881T3 (es) Metanosulfonato de paroxetina.
ES2552639T3 (es) Uso combinado de valsartán y bloqueantes de los canales de calcio para fines terapéuticos
CO4940403A1 (es) Formulaciones de liberacion prolongada de derivados de eri- tromicina
ES2167921T3 (es) Comprimido multiparticular perfeccionado de disgregacion rapida.
AR035500A1 (es) Uso de clorpromazina y pentamidina para la fabricacion de medicamentos, composicion farmaceutica y paquete farmaceutico que comprenden clorpromazina y pentamidina.
CO5190672A1 (es) Composicion para la dosificacion oral, de disolucion instantanea
DE60121570D1 (de) Oral anzuwendende schnell zerfallende feste darreichungsformen
CL2009001682A1 (es) Composición farmacéutica espontáneamente dispersable para administración oral que comprende n-benzoil-estaurosporina; método para incrementar los niveles de biodisponibilidad. (divisional de la solocitud 333-00).
AR035927A1 (es) Compuesto de lactama (n)-((s)-2-hidroxi-3-metilbutiril)-1-(l-alaninil)-(s)-1-amino-3-metil-4,5,6,7-tetrahidro-2h-3-benzazepin-2-ona , composicion farmaceutica que lo comprende, procedimiento para la inhibicion de la liberacion de peptido b-amiloide y/o su sintesis que lo emplea y su uso para la fabr
UY30537A1 (es) Formulaciones de flibanserina y metodo para fabricarlas
AR024228A1 (es) Una composicion farmaceutica que comprende un sensibilizador de insulina y otro agente antidiabetico
ES2109832T3 (es) Composicion dermatologica o farmaceutica, procedimiento de preparacion y utilizacion
TR200100931T2 (tr) Yeni sürekli salınımlı oral formülasyonlar
AR037930A1 (es) Formulaciones de acitromicina directamente compresibles
MX9308188A (es) Glucomanano de konjac facilmente disponible, como un excipiente de liberacion sostenida.
UY25544A1 (es) Forma de dosificación de nefazodona
AR011919A1 (es) FORMULACIoN EN COMPRIMIDOS O CÁPSULAS PARA TRAGAR DE PARACETAMOL (N-ACETIL-P-AMINOFENOL) Y PROCEDIMIENTO PARA PREPARARLA
GEP20063882B (en) Dosage regimen and pharmaceutical composition for emergency contraception
BR0112847A (pt) Uso de uma forma de dosagem sólida
AR035006A1 (es) Derivado de naftiridin-dibenzo[a,d]ciclohepteno-10-acetico, composicion farmaceutica, y el uso de dicho derivado para la fabricacion de un medicamento.
AR034142A1 (es) Una composicion farmaceutica, metodo para fabricar un medicamento en base a dicha composicion y uso de la composicion
ECSP003685A (es) Formulaciones orales de liberacion controlada
ECSP055895A (es) Producto farmacéutico de alergeno
AR039162A1 (es) Formulaciones de venlafaxina de liberacion extendida

Legal Events

Date Code Title Description
FC Refusal