AP564A - Polymer coated tablet comprising amoxycillin and clavulanate. - Google Patents

Polymer coated tablet comprising amoxycillin and clavulanate. Download PDF

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Publication number
AP564A
AP564A APAP/P/1995/000733A AP9500733A AP564A AP 564 A AP564 A AP 564A AP 9500733 A AP9500733 A AP 9500733A AP 564 A AP564 A AP 564A
Authority
AP
ARIPO
Prior art keywords
tablet
amoxycillin
clavulanate
tablet formulation
formulation according
Prior art date
Application number
APAP/P/1995/000733A
Other languages
English (en)
Other versions
AP9500733A0 (en
Inventor
Creighton Pierce Conley
Nigel Philip Mccreath Davidson
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP564(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AP9500733A0 publication Critical patent/AP9500733A0/xx
Application granted granted Critical
Publication of AP564A publication Critical patent/AP564A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
APAP/P/1995/000733A 1994-04-23 1995-04-13 Polymer coated tablet comprising amoxycillin and clavulanate. AP564A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408117A GB9408117D0 (en) 1994-04-23 1994-04-23 Pharmaceutical formulations

Publications (2)

Publication Number Publication Date
AP9500733A0 AP9500733A0 (en) 1995-04-30
AP564A true AP564A (en) 1996-11-21

Family

ID=10754044

Family Applications (2)

Application Number Title Priority Date Filing Date
APAP/P/1995/000733A AP564A (en) 1994-04-23 1995-04-13 Polymer coated tablet comprising amoxycillin and clavulanate.
APAP/P/1996/000868A AP9600868A0 (en) 1994-04-23 1995-04-19 Polymer coated tablet comprising amoxycillin and clavulanate.

Family Applications After (1)

Application Number Title Priority Date Filing Date
APAP/P/1996/000868A AP9600868A0 (en) 1994-04-23 1995-04-19 Polymer coated tablet comprising amoxycillin and clavulanate.

Country Status (35)

Country Link
US (1) US6051255A (da)
EP (5) EP0978276B1 (da)
JP (1) JP3622975B2 (da)
CN (1) CN1134258C (da)
AP (2) AP564A (da)
AT (6) ATE203161T1 (da)
AU (1) AU684949B2 (da)
BG (1) BG62842B1 (da)
BR (1) BR9507502A (da)
CA (1) CA2188496A1 (da)
CZ (2) CZ294168B6 (da)
DE (5) DE69528204T2 (da)
DK (4) DK0761218T3 (da)
DZ (1) DZ1876A1 (da)
ES (4) ES2182754T3 (da)
FI (1) FI964249L (da)
GB (1) GB9408117D0 (da)
GR (2) GR3035031T3 (da)
HK (1) HK1050992A1 (da)
HU (1) HU228399B1 (da)
IL (1) IL113433A (da)
MA (1) MA23528A1 (da)
MY (1) MY115351A (da)
NO (1) NO310703B1 (da)
NZ (1) NZ285080A (da)
OA (1) OA10377A (da)
PL (1) PL316966A1 (da)
PT (4) PT761218E (da)
RO (1) RO116997B1 (da)
RU (1) RU2152213C1 (da)
SA (1) SA95160343B1 (da)
SI (1) SI0758235T1 (da)
SK (1) SK282594B6 (da)
WO (1) WO1995028927A1 (da)
ZA (1) ZA953236B (da)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9407386D0 (en) 1994-04-14 1994-06-08 Smithkline Beecham Plc Pharmaceutical formulation
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
DZ2028A1 (fr) * 1995-05-03 2002-10-23 Smithkline Beecham Plc Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
NZ318282A (en) 1995-09-07 2000-01-28 Smithkline Beecham Corp Pharmaceutical formulation containing amoxycillin and clavulanate in a weight ratio of 12:1 and 20:1
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407701B (de) * 1996-08-12 2001-05-25 Biochemie Gmbh Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
GB9617780D0 (en) 1996-08-24 1996-10-02 Smithkline Beecham Plc Method of treatment
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
DE69815833T2 (de) * 1997-02-14 2004-05-19 Laboratoire Glaxosmithkline S.A.S. Amoxicillin und clavulanat enthaltende arzneizubereitungen
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
AU9540898A (en) * 1997-08-29 1999-03-22 Dsm N.V. Granules free of excipients
JP2001521910A (ja) 1997-10-31 2001-11-13 モンサント カンパニー ゲランガム錠剤コーティング
AU3817300A (en) 1999-04-01 2000-08-01 Dsm N.V. Agglomerates by crystallisation
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
IE20000271A1 (en) * 1999-04-13 2001-04-04 Beecham Pharm Pte Ltd Pharmaceutical Formulations of Amoxycillin and Potassium Clavulanate
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
WO2002002081A1 (en) * 2000-07-05 2002-01-10 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and methods of using same
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
AU2001292185A1 (en) * 2000-10-12 2002-04-22 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
US20020068078A1 (en) * 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
RU2324475C2 (ru) * 2001-04-10 2008-05-20 Сан Фармасьютикал Индастриз Лимитед Состав, выделяемый в импульсном режиме в заданное время
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
WO2003066053A1 (en) * 2002-02-07 2003-08-14 Rutgers, The State University Antibiotic polymers
GB0203528D0 (en) * 2002-02-14 2002-04-03 Glaxo Group Ltd Process and composition
JP2005523276A (ja) * 2002-02-14 2005-08-04 グラクソ グループ リミテッド N−[(1−n−ブチル−4−ピペリジニル)メチル]−3,4−ジヒドロ−2h−[1,3]オキサジノ[3,2−a]インドール−10−カルボキシアミド(sb207266)またはその塩および乾燥造粒操作を含む方法
US20060083759A1 (en) * 2002-07-17 2006-04-20 Aleksander Resman Stabilization of the profile of release of active substances from a formulation
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
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US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CL2008003230A1 (es) * 2007-11-01 2009-11-27 Sanofi Aventis Healthcare Pty Ltd Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta.
UA107582C2 (uk) * 2009-09-18 2015-01-26 Таблетований препарат (4'-трифторметилфеніл)аміду (z)-2-ціано-гідроксибут-2-еноєвої кислоти з поліпшеною стійкістю
TR200909787A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
TR201000686A1 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232005A (en) * 1975-04-14 1980-11-04 Beecham Group Limited Antibacterial agents
US4441609A (en) * 1977-10-11 1984-04-10 Beecham Group Limited Pharmaceutical compositions
US4537887A (en) * 1980-09-27 1985-08-27 Beecham Group Limited Pharmaceutical formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241844A (en) 1968-08-23 1971-08-04 Beecham Group Ltd Penicillins
GB1508977A (en) 1974-04-20 1978-04-26 Beecham Group Ltd Beta-lactam antibiotic from streptomyces clavuligerus
EP0080862B1 (en) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
GB9408117D0 (en) * 1994-04-23 1994-06-15 Smithkline Beecham Corp Pharmaceutical formulations
IE20000271A1 (en) * 1999-04-13 2001-04-04 Beecham Pharm Pte Ltd Pharmaceutical Formulations of Amoxycillin and Potassium Clavulanate
AU2001292185A1 (en) * 2000-10-12 2002-04-22 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232005A (en) * 1975-04-14 1980-11-04 Beecham Group Limited Antibacterial agents
US4441609A (en) * 1977-10-11 1984-04-10 Beecham Group Limited Pharmaceutical compositions
US4537887A (en) * 1980-09-27 1985-08-27 Beecham Group Limited Pharmaceutical formulation

Also Published As

Publication number Publication date
DE69519093T2 (de) 2001-07-19
ES2152485T3 (es) 2001-02-01
HK1027024A1 (en) 2001-01-05
DE29522153U1 (de) 2000-04-06
RU2152213C1 (ru) 2000-07-10
EP1243267A2 (en) 2002-09-25
NO310703B1 (no) 2001-08-20
HK1009936A1 (en) 1999-06-11
EP0978276A3 (en) 2000-04-12
AP9600868A0 (en) 1996-10-31
MY115351A (en) 2003-05-31
EP0758235A1 (en) 1997-02-19
JP3622975B2 (ja) 2005-02-23
HU228399B1 (en) 2013-03-28
EP0978276B1 (en) 2002-09-11
SA95160343B1 (ar) 2005-05-04
PT758235E (pt) 2001-10-31
DE69528608D1 (de) 2002-11-21
ES2161288T3 (es) 2001-12-01
EP1093813A3 (en) 2001-05-30
ATE226074T1 (de) 2002-11-15
HK1021860A1 (en) 2000-07-07
ES2182754T3 (es) 2003-03-16
DE69528204T2 (de) 2003-08-07
ATE223706T1 (de) 2002-09-15
RO116997B1 (ro) 2001-09-28
AT5350U1 (de) 2002-06-25
GB9408117D0 (en) 1994-06-15
NZ285080A (en) 1998-05-27
CN1149829A (zh) 1997-05-14
DK0978276T3 (da) 2003-01-20
AU2406895A (en) 1995-11-16
DK0758235T3 (da) 2001-10-29
AU684949B2 (en) 1998-01-08
GR3036844T3 (en) 2002-01-31
CA2188496A1 (en) 1995-11-02
CN1134258C (zh) 2004-01-14
HUT76335A (en) 1997-08-28
HK1036404A1 (en) 2002-01-04
NO964488L (no) 1996-12-17
IL113433A (en) 2003-06-24
BG100933A (en) 1997-07-31
SK135496A3 (en) 1997-05-07
MA23528A1 (fr) 1995-12-31
BG62842B1 (bg) 2000-09-29
GR3035031T3 (en) 2001-03-30
DE69521799D1 (de) 2001-08-23
DK1093813T3 (da) 2003-02-17
ATE196845T1 (de) 2000-10-15
US6051255A (en) 2000-04-18
SI0758235T1 (en) 2001-10-31
AP9500733A0 (en) 1995-04-30
EP0758235B1 (en) 2001-07-18
FI964249A7 (fi) 1996-10-22
HU9602922D0 (en) 1996-12-30
EP1243267A3 (en) 2002-10-30
DE69528608T2 (de) 2003-06-26
PL316966A1 (en) 1997-03-03
JPH09512027A (ja) 1997-12-02
IL113433A0 (en) 1995-07-31
EP0978276A2 (en) 2000-02-09
DE69519093D1 (de) 2000-11-16
CZ309096A3 (en) 1997-04-16
FI964249A0 (fi) 1996-10-22
PT761218E (pt) 2001-03-30
DE69528204D1 (de) 2002-10-17
BR9507502A (pt) 1997-09-02
HK1050992A1 (en) 2003-07-18
SK282594B6 (sk) 2002-10-08
EP0761218B1 (en) 2000-10-11
DK0761218T3 (da) 2000-12-18
EP0761218A1 (en) 1997-03-12
CZ294168B6 (cs) 2004-10-13
WO1995028927A1 (en) 1995-11-02
EP1093813A2 (en) 2001-04-25
ATE203161T1 (de) 2001-08-15
DZ1876A1 (fr) 2002-02-17
EP1093813B1 (en) 2002-10-16
ZA953236B (en) 1995-12-27
PT1093813E (pt) 2003-02-28
OA10377A (en) 2001-11-21
PT978276E (pt) 2003-01-31
NO964488D0 (no) 1996-10-22
FI964249L (fi) 1996-10-22
DE69521799T2 (de) 2002-06-13
CZ11376U1 (cs) 2001-07-12
ES2180251T3 (es) 2003-02-01
AT5349U1 (de) 2002-06-25

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