ZA991489B - Oxaliplatin solution formulations and the method of use thereof. - Google Patents

Oxaliplatin solution formulations and the method of use thereof.

Info

Publication number
ZA991489B
ZA991489B ZA9901489A ZA991489A ZA991489B ZA 991489 B ZA991489 B ZA 991489B ZA 9901489 A ZA9901489 A ZA 9901489A ZA 991489 A ZA991489 A ZA 991489A ZA 991489 B ZA991489 B ZA 991489B
Authority
ZA
South Africa
Prior art keywords
solution formulations
oxaliplatin solution
oxaliplatin
formulations
solution
Prior art date
Application number
ZA9901489A
Other languages
English (en)
Inventor
Nicholas H Anderson
Stephen Brown
David A England
Ross Blundell
Martin R Gray
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10827600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA991489(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA991489B publication Critical patent/ZA991489B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA9901489A 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof. ZA991489B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9804013.2A GB9804013D0 (en) 1998-02-25 1998-02-25 Formulations

Publications (1)

Publication Number Publication Date
ZA991489B true ZA991489B (en) 1999-09-30

Family

ID=10827600

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901489A ZA991489B (en) 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof.

Country Status (28)

Country Link
US (1) US6306902B1 (fr)
EP (1) EP0943331B1 (fr)
JP (1) JP4430229B2 (fr)
KR (1) KR20010041182A (fr)
CN (1) CN1152718C (fr)
AR (1) AR015524A1 (fr)
AT (1) ATE202472T1 (fr)
AU (1) AU757101B2 (fr)
BR (1) BR9908273A (fr)
CA (1) CA2261500C (fr)
CZ (1) CZ302196B6 (fr)
DE (1) DE69900162T2 (fr)
DK (1) DK0943331T3 (fr)
ES (1) ES2161085T3 (fr)
GB (1) GB9804013D0 (fr)
GR (1) GR3036646T3 (fr)
GT (1) GT199900019A (fr)
HK (1) HK1036405A1 (fr)
HU (1) HU224611B1 (fr)
IL (1) IL137772A (fr)
MX (1) MXPA00008195A (fr)
NO (1) NO329900B1 (fr)
PL (1) PL197948B1 (fr)
PT (1) PT943331E (fr)
RU (1) RU2207857C2 (fr)
UA (1) UA70316C2 (fr)
WO (1) WO1999043355A2 (fr)
ZA (1) ZA991489B (fr)

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GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations
CA2346564C (fr) * 1998-10-14 2011-05-03 Debiopharm S.A. Conditionnement d'une preparation d'oxaliplatine
WO2001015691A1 (fr) * 1999-08-30 2001-03-08 Debiopharm S.A. Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
US7012072B2 (en) * 2000-12-12 2006-03-14 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
WO2002069959A1 (fr) 2001-03-02 2002-09-12 Debiopharm S.A. Dispositif de conditionnement d'une solution d'oxaliplatine
EP1404689A1 (fr) 2001-07-02 2004-04-07 Debiopharm S.A. Substance active a base d'oxaliplatine presentant une faible teneur en acide oxalique
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (fr) * 2002-05-31 2003-11-30 Voiceage Corporation Methode et dispositif pour l'amelioration selective en frequence de la hauteur de la parole synthetisee
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
US20050020556A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
NZ545591A (en) * 2003-08-28 2008-11-28 Mayne Pharma Ltd Acid containing oxaliplatin formulations
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ，エー．エス． 医薬組成物、その製造方法及び治療上の使用
CZ300795B6 (cs) * 2003-09-02 2009-08-12 Pliva-Lachema A. S. Farmaceutická kompozice a zpusob její výroby
US7576126B2 (en) 2003-11-25 2009-08-18 Platco Technologies (Proprietary) Limited Platinum (II) complexes, preparation and use
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
WO2005102312A1 (fr) * 2004-04-27 2005-11-03 Mayne Pharma Limited Solutions concentrees d'oxaliplatine
EP2011798B1 (fr) 2004-09-01 2011-06-29 Platco Technologies (Proprietary) Limited Préparation de complexes de platine (II)
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
ATE430564T1 (de) * 2005-03-28 2009-05-15 Dabur Pharma Ltd Stabile pharmazeutische zusammensetzungen aus antitumoralen platin-(ii)-mitteln
CA2604862A1 (fr) * 2005-04-09 2006-10-19 Vuab Pharma A.S. Procede de realisation d'une preparation a base d'oxalyplatine
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (fr) * 2005-09-05 2007-03-15 Dabur Pharma Limited Formulation stable d'oxaliplatine
CN101389637A (zh) 2006-01-30 2009-03-18 普拉托技术（私有）公司 铂(ⅱ)配合物的制备
KR100913063B1 (ko) 2006-09-13 2009-08-21 주식회사유한양행 옥살리플라틴-함유 주사용 용액
US20100093849A1 (en) * 2007-01-22 2010-04-15 Borek Zaludek Oxaliplatin pharmaceutical composition with alcoholic sugar-based buffer
EP2152239A1 (fr) * 2007-11-12 2010-02-17 Intas Pharmaceuticals Limited Composition d'oxaliplatine stable pour une administration parentérale
US20090130017A1 (en) * 2007-11-19 2009-05-21 Searete Llc Targeted short-lived drug delivery
WO2010056847A2 (fr) * 2008-11-13 2010-05-20 Taigen Biotechnology Co., Ltd. Formule lyophilisée
CN101461801B (zh) * 2008-12-26 2013-05-15 辰欣药业股份有限公司 一种奥沙利铂药物组合物及其制备方法
EP2481396A4 (fr) 2009-09-21 2014-03-05 Jw Pharmaceutical Corp Nanoparticules d'oxaliplatine et leur procédé de préparation
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
CN104523674B (zh) * 2014-12-11 2017-10-24 广州市上为医药科技有限公司 一种以奥沙利铂为主药成分的注射用组合物
KR101683635B1 (ko) 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CN104829653B (zh) * 2015-05-06 2016-03-23 山东罗欣药业集团股份有限公司 一种奥沙利铂水合物晶体及其冻干粉针剂
TWI827577B (zh) 2018-01-12 2024-01-01 南韓商梅堤梅蒂製藥有限公司 治療慢性發炎疾病的方法

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PT93772A (pt) 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
EP0464210A4 (en) 1989-12-15 1992-11-25 Tsumura & Co. Novel platinum complex and antitumor drug containing the same as active ingredient
JPH04185601A (ja) * 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
AU671605B2 (en) * 1991-11-15 1996-09-05 Smithkline Beecham Corporation Combination chemotherapy
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JPH05238936A (ja) 1992-02-27 1993-09-17 Dainippon Pharmaceut Co Ltd カルシトリオールの水性液剤
JP2673331B2 (ja) * 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
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AU5416394A (en) * 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
JP3025602B2 (ja) * 1993-05-21 2000-03-27 デビオファーム エス．アー． 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法
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ES2152412T3 (es) 1994-08-08 2001-02-01 Debiopharm Sa Preparacion farmaceuticamente estable de oxaliplatino.
ES2206478T3 (es) * 1994-11-11 2004-05-16 Debiopharm S.A. Composiciones carcinostaticas que contienen cis-oxaliplatino y otra u otras sustancias carcinostaticas compatibles.
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DK0801070T3 (da) 1996-04-10 2003-05-19 Debiopharm Sa Fremgangsmåde til fremstilling af platinforbindelse
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GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations

Also Published As

Publication number Publication date
MXPA00008195A (es) 2004-11-22
HUP0103707A2 (hu) 2002-02-28
CN1152718C (zh) 2004-06-09
BR9908273A (pt) 2000-10-24
GB9804013D0 (en) 1998-04-22
NO20004240D0 (no) 2000-08-24
RU2207857C2 (ru) 2003-07-10
GR3036646T3 (en) 2001-12-31
EP0943331A2 (fr) 1999-09-22
IL137772A (en) 2006-04-10
CN1291886A (zh) 2001-04-18
CA2261500C (fr) 2001-07-17
AU2632499A (en) 1999-09-15
JP4430229B2 (ja) 2010-03-10
UA70316C2 (uk) 2004-10-15
KR20010041182A (ko) 2001-05-15
WO1999043355A3 (fr) 1999-11-04
PT943331E (pt) 2001-12-28
AU757101B2 (en) 2003-01-30
PL343021A1 (en) 2001-07-30
CZ302196B6 (cs) 2010-12-15
CA2261500A1 (fr) 1999-08-25
AR015524A1 (es) 2001-05-02
PL197948B1 (pl) 2008-05-30
NO329900B1 (no) 2011-01-24
WO1999043355A2 (fr) 1999-09-02
DE69900162T2 (de) 2002-04-18
DE69900162D1 (de) 2001-08-02
DK0943331T3 (da) 2001-10-15
NO20004240L (no) 2000-10-18
CZ20003089A3 (cs) 2000-12-13
ATE202472T1 (de) 2001-07-15
HU224611B1 (hu) 2005-11-28
EP0943331A3 (fr) 1999-11-03
EP0943331B1 (fr) 2001-06-27
HK1036405A1 (en) 2002-01-04
HUP0103707A3 (en) 2004-07-28
ES2161085T3 (es) 2001-11-16
GT199900019A (es) 2000-08-04
JP2002504524A (ja) 2002-02-12
US6306902B1 (en) 2001-10-23

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