ZA991489B - Oxaliplatin solution formulations and the method of use thereof. - Google Patents

Oxaliplatin solution formulations and the method of use thereof.

Info

Publication number
ZA991489B
ZA991489B ZA9901489A ZA991489A ZA991489B ZA 991489 B ZA991489 B ZA 991489B ZA 9901489 A ZA9901489 A ZA 9901489A ZA 991489 A ZA991489 A ZA 991489A ZA 991489 B ZA991489 B ZA 991489B
Authority
ZA
South Africa
Prior art keywords
solution formulations
oxaliplatin solution
oxaliplatin
formulations
solution
Prior art date
Application number
ZA9901489A
Other languages
English (en)
Inventor
Nicholas H Anderson
Stephen Brown
David A England
Ross Blundell
Martin R Gray
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10827600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA991489(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA991489B publication Critical patent/ZA991489B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA9901489A 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof. ZA991489B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9804013.2A GB9804013D0 (en) 1998-02-25 1998-02-25 Formulations

Publications (1)

Publication Number Publication Date
ZA991489B true ZA991489B (en) 1999-09-30

Family

ID=10827600

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901489A ZA991489B (en) 1998-02-25 1999-02-24 Oxaliplatin solution formulations and the method of use thereof.

Country Status (28)

Country Link
US (1) US6306902B1 (es)
EP (1) EP0943331B1 (es)
JP (1) JP4430229B2 (es)
KR (1) KR20010041182A (es)
CN (1) CN1152718C (es)
AR (1) AR015524A1 (es)
AT (1) ATE202472T1 (es)
AU (1) AU757101B2 (es)
BR (1) BR9908273A (es)
CA (1) CA2261500C (es)
CZ (1) CZ302196B6 (es)
DE (1) DE69900162T2 (es)
DK (1) DK0943331T3 (es)
ES (1) ES2161085T3 (es)
GB (1) GB9804013D0 (es)
GR (1) GR3036646T3 (es)
GT (1) GT199900019A (es)
HK (1) HK1036405A1 (es)
HU (1) HU224611B1 (es)
IL (1) IL137772A (es)
MX (1) MXPA00008195A (es)
NO (1) NO329900B1 (es)
PL (1) PL197948B1 (es)
PT (1) PT943331E (es)
RU (1) RU2207857C2 (es)
UA (1) UA70316C2 (es)
WO (1) WO1999043355A2 (es)
ZA (1) ZA991489B (es)

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AU762138B2 (en) * 1998-10-14 2003-06-19 Debiopharm S.A. Oxaliplatinum preparation packaging
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
BRPI0013613B8 (pt) * 1999-08-30 2021-05-25 Debiopharm Sa composição farmacêuticamente estável de oxaliplatina para administração parenteral.
US7012072B2 (en) * 2000-12-12 2006-03-14 Debiopharm S.A. Pharmaceutical oxaliplatinum preparation for parenteral administration and method for obtaining same
EP1368022B1 (fr) 2001-03-02 2007-06-20 Debiopharm S.A. Utilisation d'un flacon contenant une solution d'oxaliplatine
WO2003004505A1 (en) 2001-07-02 2003-01-16 Debiopharm S.A. Oxaliplatin active substance with a very low content of oxalic acid
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
US20050020556A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ,エー.エス. 医薬組成物、その製造方法及び治療上の使用
CZ300795B6 (cs) * 2003-09-02 2009-08-12 Pliva-Lachema A. S. Farmaceutická kompozice a zpusob její výroby
JP2007512318A (ja) 2003-11-25 2007-05-17 プラトコ・テクノロジーズ・(プロプライエタリー)・リミテッド 白金(ii)錯体並びに該錯体の製法及び使用
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
WO2005102312A1 (en) * 2004-04-27 2005-11-03 Mayne Pharma Limited Concentrated oxaliplatin solutions
CN101018797A (zh) 2004-09-01 2007-08-15 普拉托技术(私有)有限公司 铂(ⅱ)配合物的制备
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
AU2005329764B2 (en) * 2005-03-28 2010-08-12 Dabur Pharma Ltd. Stable pharmaceutical compositions of platinum (II) antitumour agents
CA2604862A1 (en) * 2005-04-09 2006-10-19 Vuab Pharma A.S. A process for the preparation of an oxaliplatin preparation
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
KR20080096682A (ko) 2006-01-30 2008-10-31 플라트코 테크놀로지스 (프로프라이어터리) 리미티드 백금(ⅱ) 착물의 제조법
KR100913063B1 (ko) 2006-09-13 2009-08-21 주식회사유한양행 옥살리플라틴-함유 주사용 용액
MX2009007801A (es) * 2007-01-22 2009-10-08 Pliva Lachema As Composicion farmaceutica de oxaliplatino con regulador basado en azucar alcoholico.
WO2009087660A1 (en) * 2007-11-12 2009-07-16 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
US20090130017A1 (en) * 2007-11-19 2009-05-21 Searete Llc Targeted short-lived drug delivery
WO2010056847A2 (en) * 2008-11-13 2010-05-20 Taigen Biotechnology Co., Ltd. Lyophilization formulation
CN101461801B (zh) * 2008-12-26 2013-05-15 辰欣药业股份有限公司 一种奥沙利铂药物组合物及其制备方法
JP5759464B2 (ja) 2009-09-21 2015-08-05 ジェイダブリュー ファーマシューティカル コーポレイション オキサリプラチンのナノ粒子及びその製造方法
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
CN104523674B (zh) * 2014-12-11 2017-10-24 广州市上为医药科技有限公司 一种以奥沙利铂为主药成分的注射用组合物
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CN104829653B (zh) * 2015-05-06 2016-03-23 山东罗欣药业集团股份有限公司 一种奥沙利铂水合物晶体及其冻干粉针剂
US10751365B2 (en) 2018-01-12 2020-08-25 Metimedi Pharmaceuticals Co., Ltd. Methods of treating chronic inflammatory diseases

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PT93772A (pt) 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
EP0464210A4 (en) 1989-12-15 1992-11-25 Tsumura & Co. Novel platinum complex and antitumor drug containing the same as active ingredient
JPH04185601A (ja) 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
AU671605B2 (en) 1991-11-15 1996-09-05 Smithkline Beecham Corporation Combination chemotherapy
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JPH05238936A (ja) 1992-02-27 1993-09-17 Dainippon Pharmaceut Co Ltd カルシトリオールの水性液剤
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JP2673331B2 (ja) * 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート(トランス―1―1,2―シクロヘキサンジアミン)白金(▲ii▼)
AU5416394A (en) * 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
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US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
KR100365171B1 (ko) 1994-08-08 2003-02-19 드바이오팜 에스.아. 약학적으로안정한옥살리플라티늄제제
DE69531722T2 (de) * 1994-11-11 2004-07-01 Debiopharm S.A. Karzinostatische Zusammensetzungen, welche Cis-Oxaliplatin und eine oder mehrere andere verträgliche Karzinostatika enthalten
FR2740686B1 (fr) * 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable
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GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations

Also Published As

Publication number Publication date
AR015524A1 (es) 2001-05-02
CA2261500A1 (en) 1999-08-25
CZ302196B6 (cs) 2010-12-15
IL137772A (en) 2006-04-10
DE69900162T2 (de) 2002-04-18
JP4430229B2 (ja) 2010-03-10
EP0943331A2 (en) 1999-09-22
GB9804013D0 (en) 1998-04-22
MXPA00008195A (es) 2004-11-22
JP2002504524A (ja) 2002-02-12
US6306902B1 (en) 2001-10-23
NO20004240L (no) 2000-10-18
WO1999043355A2 (en) 1999-09-02
HK1036405A1 (en) 2002-01-04
UA70316C2 (uk) 2004-10-15
EP0943331A3 (en) 1999-11-03
CN1291886A (zh) 2001-04-18
CA2261500C (en) 2001-07-17
CN1152718C (zh) 2004-06-09
WO1999043355A3 (en) 1999-11-04
RU2207857C2 (ru) 2003-07-10
PT943331E (pt) 2001-12-28
DE69900162D1 (de) 2001-08-02
NO329900B1 (no) 2011-01-24
NO20004240D0 (no) 2000-08-24
GR3036646T3 (en) 2001-12-31
HUP0103707A2 (hu) 2002-02-28
DK0943331T3 (da) 2001-10-15
PL197948B1 (pl) 2008-05-30
ATE202472T1 (de) 2001-07-15
ES2161085T3 (es) 2001-11-16
AU2632499A (en) 1999-09-15
PL343021A1 (en) 2001-07-30
CZ20003089A3 (cs) 2000-12-13
HUP0103707A3 (en) 2004-07-28
AU757101B2 (en) 2003-01-30
EP0943331B1 (en) 2001-06-27
GT199900019A (es) 2000-08-04
BR9908273A (pt) 2000-10-24
HU224611B1 (hu) 2005-11-28
KR20010041182A (ko) 2001-05-15

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