ZA989385B - Methods for treating hypercoagulable states or acquired protein C deficiency. - Google Patents

Methods for treating hypercoagulable states or acquired protein C deficiency.

Info

Publication number
ZA989385B
ZA989385B ZA9809385A ZA989385A ZA989385B ZA 989385 B ZA989385 B ZA 989385B ZA 9809385 A ZA9809385 A ZA 9809385A ZA 989385 A ZA989385 A ZA 989385A ZA 989385 B ZA989385 B ZA 989385B
Authority
ZA
South Africa
Prior art keywords
deficiency
methods
hypercoagulable states
acquired protein
apc
Prior art date
Application number
ZA9809385A
Other languages
English (en)
Inventor
Brian William Grinnell
Daniel Lawrence Hartman
Sau-Chi Betty Yan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA989385B publication Critical patent/ZA989385B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
ZA9809385A 1997-10-20 1998-10-14 Methods for treating hypercoagulable states or acquired protein C deficiency. ZA989385B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6254997P 1997-10-20 1997-10-20
US6476597P 1997-11-07 1997-11-07

Publications (1)

Publication Number Publication Date
ZA989385B true ZA989385B (en) 2000-04-14

Family

ID=26742406

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9809385A ZA989385B (en) 1997-10-20 1998-10-14 Methods for treating hypercoagulable states or acquired protein C deficiency.

Country Status (28)

Country Link
US (7) US6037322A (xx)
EP (2) EP1449537A3 (xx)
JP (2) JP3805981B2 (xx)
KR (1) KR100798174B1 (xx)
CN (1) CN1276726A (xx)
AT (1) ATE292979T1 (xx)
AU (1) AU748417B2 (xx)
BR (1) BR9812965A (xx)
CA (1) CA2306983A1 (xx)
DE (1) DE69829721T2 (xx)
DK (1) DK0913156T3 (xx)
EA (1) EA002496B1 (xx)
ES (1) ES2239382T3 (xx)
HK (1) HK1020529A1 (xx)
HU (2) HUP0001237A3 (xx)
ID (1) ID24901A (xx)
IL (2) IL135712A0 (xx)
MY (1) MY117655A (xx)
NO (1) NO20002005L (xx)
NZ (1) NZ504026A (xx)
PL (1) PL200515B1 (xx)
PT (1) PT913156E (xx)
SI (1) SI0913156T1 (xx)
TR (1) TR200001059T2 (xx)
TW (1) TWI225404B (xx)
UA (1) UA72194C2 (xx)
WO (1) WO1999020293A1 (xx)
ZA (1) ZA989385B (xx)

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KR20040040489A (ko) 2001-10-15 2004-05-12 카이론 코포레이션 조직 인자 경로 억제제（ｔｆｐｉ）의 저용량 투여에 의한패혈증의 치료
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KR102263556B1 (ko) 2018-06-15 2021-06-10 에이비 산드빅 매터리얼즈 테크놀로지 2 상 스테인리스 강 스트립 및 그 제조 방법

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Also Published As

Publication number Publication date
MY117655A (en) 2004-07-31
SI0913156T1 (en) 2005-10-31
HU224901B1 (en) 2006-04-28
HUP0100025A2 (hu) 2001-05-28
ATE292979T1 (de) 2005-04-15
US6268344B1 (en) 2001-07-31
US6037322A (en) 2000-03-14
UA72194C2 (en) 2005-02-15
NO20002005D0 (no) 2000-04-17
US6008199A (en) 1999-12-28
WO1999020293A1 (en) 1999-04-29
PL340096A1 (en) 2001-01-15
NZ504026A (en) 2002-12-20
JP2005097313A (ja) 2005-04-14
TR200001059T2 (tr) 2000-10-23
US20010036456A1 (en) 2001-11-01
US6268337B1 (en) 2001-07-31
IL135712A0 (en) 2001-05-20
AU748417B2 (en) 2002-06-06
KR20010031217A (ko) 2001-04-16
HK1020529A1 (en) 2000-05-12
US6426071B2 (en) 2002-07-30
DE69829721T2 (de) 2006-02-09
BR9812965A (pt) 2001-03-20
HUP0001237A2 (hu) 2000-08-28
EA002496B1 (ru) 2002-06-27
CN1276726A (zh) 2000-12-13
US6489296B1 (en) 2002-12-03
PT913156E (pt) 2005-08-31
PL200515B1 (pl) 2009-01-30
CA2306983A1 (en) 1999-04-29
EP0913156A1 (en) 1999-05-06
HUP0001237A3 (en) 2002-01-28
KR100798174B1 (ko) 2008-01-24
JP2001520199A (ja) 2001-10-30
EA200000445A1 (ru) 2000-10-30
DK0913156T3 (da) 2005-06-27
US6156734A (en) 2000-12-05
EP1449537A3 (en) 2005-09-21
AU9804098A (en) 1999-05-10
TWI225404B (en) 2004-12-21
NO20002005L (no) 2000-05-16
EP0913156B1 (en) 2005-04-13
IL135712A (en) 2010-12-30
DE69829721D1 (de) 2005-05-19
ES2239382T3 (es) 2005-09-16
EP1449537A2 (en) 2004-08-25
HUP0100025A3 (en) 2003-08-28
ID24901A (id) 2000-08-31
JP3805981B2 (ja) 2006-08-09

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